61results about How to "The synthesis method is safe" patented technology

The invention discloses a preparation method of magnetic/gold nano particles. The preparation method comprises the following steps: firstly adopting a co-precipitation method to prepare the magnetic Fe3O4 nano particles; polymerizing the dopamine in-situ on the surfaces of the magnetic particles to obtain Fe3O4 nano particles modified by the poly dopamine; introducing polyphenol and amino groups to the surfaces of the Fe3O4 nano particles; absorbing the nano gold seeds on the surfaces of the modified magnetic particles through the static action; adopting the nano gold which is absorbed on the surfaces of the magnetic particles as the seed, adopting the polyphenol on the surfaces of the magnetic particles as a reducing agent, gradually adding the chloroauric acid liquid to gradually produce the gold layers on the surfaces of the magnetic particles to obtain the core-shell magnetic/gold nano particles. The nano particles have good water dispersion and strong magnetic respond performance. The diameters of the nano particles are 30-100 nanometers, the saturation magnetization is 30.1-38.7emu/g, and the nano particles are superparamagnetic. The nano particles have wide application prospect on the fields of targeted drug controlled release, thermal therapy, separation of protein and enzyme, etc.

This invention discloses a cellulose base chelated textile fiber and the synthetic method and the application. The chelated textile fiber takes the native cellulose textile fiber as the raw material. Through the duplet bond and the shrinkage glycerin compound carries on the free radical stem grafting copolymerization, we obtain the cellulose textile fiber which the epoxy activates, this epoxy activates the cellulose textile fiber and the polyethylene multi-amines respond a lot the amine chelated textile fiber, the multi-amine chelated textile fiber continues with the chloroacetic acid to respond, multi-amine multi-carboxylic acid chelated textile fiber. This kind of cellulose base chelated textile fiber has the fine trapping performance to the harmful heavy metal ion, and the synthetic method is simple, safe. the synthesis cost is low, too.

The invention belongs to the technical fields of catalysts and xylosic acid, and discloses a modified carbon nitride photocatalyst, a preparation method thereof, and a method for synthesizing xylosicacid by photocatalytic oxidation of xylose. The preparation method of the photocatalyst comprises the following steps: (1) uniformly mixing a nitrogen-containing organic matter precursor with a low-melting point chlorine-containing salt compound in a solvent, and removing the solvent to obtain a solid product; and (2) performing calcining, acid treatment, washing and drying on the solid product toobtain the modified carbon nitride photocatalyst. The modified carbon nitride photocatalyst is used for photocatalytic oxidation of xylose to synthesize xylosic acid. The method for synthesizing xylosic acid is characterized in that the photocatalytic oxidation of the xylose is carried out in an alkaline solution under an illuminating condition in the presence of the modified carbon nitride photocatalyst to obtain the xylosic acid. The photocatalyst has the advantages of good thermal stability, high catalytic activity and good recyclability. The method for successfully synthesizing xylosic acid by photocatalytic oxidation of xylose through using the photocatalyst has the advantages of good safety, non-toxicity, quick effect, low energy consumption, high yield of the xylosic acid, and easiness in realizing industrial production.

The invention provides a synthetic method for preparing alpha, beta-unsaturated ketone, and relates to the technical field of medicines, pesticides, spices and the like. The synthetic method is characterized in that under the catalysis of calcium hydroxide, in a low-concentration alcohol solution, the alpha, beta-unsaturated ketone is directly synthesized by aldehyde ketone through one-step aldol condensation. The calcium hydroxide as a catalyst used in the method is cheap and rich, and after the completion of the reaction, carbon dioxide can be introduced to remove calcium hydroxide. As the method uses the low-concentration alcohol solution, cleanness and environmental protection are achieved. Therefore, the synthetic method is eco-friendly, small in equipment corrosion, durable and more suitable for industrial production.

The invention relates to the technical field of biology, in particular to a method for biosynthesizing nano-silver through photoinduction of imperata leaf extract. The method comprises the following steps: 1) picked imperata leaves are cleaned, dried and grinded to powder; ultrapure water is added in the powder for oscillating, extracting and centrifugating to obtain supernatant; and the supernatant is frozen and dried to obtain the imperata leaf extract; and 2) the imperata leaf extract in the step 1) is taken as a reaction matrix; AgNO3 solution is added, so that the concentration of the reaction matrix in obtained mixed solution is 10-50 mg/mL, and the concentration of AgNO3 is 1-3 mM; and nano-silver particles are prepared through reaction under sunlight irradiation or LED lamp irradiation. The biosynthesizing method is safe, environment-friendly, wide in synthetic material source and fast in synthesizing speed, can finish the reaction within 90-120 minutes, and is a green, safe and efficient biosynthesizing method.

The invention provides a guanidine substituted aromatic compound modified high polymer material shown in a formula (1). The guanidine substituted aromatic compound modified high polymer material comprises a cationic high polymer skeleton and guanidine substituted aromatic compound functional groups, and the guanidine substituted aromatic compound functional groups are covalently connected to the surface of the cationic high polymer skeleton. The invention further provides a preparation method of the high polymer material and an application of the high polymer material as a nucleic acid and protein molecule transport carrier. The synthesis method has low cost and is simple; the synthesized high polymer material is low in cytotoxicity and has the good application prospect.

The invention relates to a preparation method of 4-benzyl piperazi ethyliminumacyl (formimidoyl benzol) hydrazine compounds, and specifically relates to a method for preparing a compound of the following formula I or its pharmaceutically acceptable salts or solvates, wherein, R1, R2, R3 and R4 are respectively selected from hydrogen atom, hydroxyl, halogen, C1-8 alkenyl, C1-8 alkyl and sulfonamido. The method comprises the step of: (1) in a suitable organic solvent, reacting hydrazine hydrate with the compound of formula 1a so as to obtain the compound of formula 1b; (2) with the existence of alkali, reacting 2-chloracetyl iminoiacetate hydrochloride with the compound of formula 1b in a suitable organic solvent so as to generate the compound of formula 1c; (3) in the presence of alkali and in a proper organic solvent, reacting the compound of formula 1c with the compound of formula 1d, thus obtaining the compound of formula I. The method of the invention is characterized by security, simplicity and convenient operation.

The invention relates to a preparation method of an indium antimonide nanocrystal, belonging to the technical field of a composite nanocrystal material. The product of the preparation method is the indium antimonide nanocrystal. The preparation method of the indium antimonide nanocrystal comprises steps of: mixing Sb2O3, In(NO3)3.9/2H2O, PEG200 (polyethylene glycol) with ethanediol in a 250ml three-necked flask, wherein the mixture is taken as growth solution; dissolving NaBH4 into ethidene diamine to be taken as storage solution; performing the oil bath on the growth solution until the temperature of the solution is 140 DEG C under the protective atmosphere of the nitrogen, and keeping the magnetic stirring for 30 minutes; adjusting the oil bath temperature at reaction temperature (120 DEG C-180 DEG C); fast injecting the storage solution into the growth solution (-2S) by a needle cylinder, and keeping the oil bath temperature and the magnetic stirring; sampling reaction solution within the reaction time from 5 minutes to 5 hours; and adding the alcohol with proper amount into the sampled reaction solution, and centrifuging for 20 minutes at the rotation speed of 15000rpm to separate the product (InSb). The preparation method is a liquid phase preparation method for preparing the InSb nanocrystal at a lower temperature (120-180 DEG C), wherein the method is high-efficiency, low-priced, free of catalytic agent and relatively safe; the prepared product is stable in property, and even in particle; and the preparation method can be used for providing the indium antimonide nanocrystal which is suitable for a high-speed electronic component, a magnetic component, and a far infrared-waveband photoelectric component.

The invention belongs to the field of chemical synthesis, and discloses a method for synthesizing 4-S-2', 3', 5'-O-triacetyluridine. According to the synthesis method, a compound 2', 3', 5'-O-triacetyluridine is used as a raw material, phosphorus pentasulfide and a Lawesson's reagent are combined to be used as a vulcanizing agent, 1,4-dioxane is used as a solvent for chemical reaction, and finally4-S-2', 3', 5'-O-triacetyluridine is prepared. By the method for synthesizing 4-S-2', 3', 5'-O-triacetyluridine provided by the invention, the reaction time is shortened, and moreover, the vulcanization efficiency is greatly improved. According to the synthesis method provided by the invention, the cost is reduced, the reaction aftertreatment is simple and convenient, and meanwhile, the yield ofa reaction thionucleoside compound is improved.

The invention discloses an imidazolecarboxylic acid complex and a synthesis method and application thereof. The chemical formula of the imidazolecarboxylic acid complex is [Cd(L)<1/2>.2H2O]n, wherein a ligand L is 2,2'-(1,2-phenyl)bis(1H-imidazole-4,5-dicarboxylic acid). The brand new imidazolecarboxylic acid complex is obtained by taking 2,2'-(1,2-phenyl)bis(1H-imidazole-4,5-dicarboxylic acid) as a bridging ligand and constructing a coordination polymer by means of 2,2'-(1,2-phenyl)bis(1H-imidazole-4,5-dicarboxylic acid) and metal ions Cd<2+>. According to the method, Cd(Ac)2.2H2O and 2,2'-(1,2-phenyl)bis(1H-imidazole-4,5-dicarboxylic acid) react through a hydrothermal method, the ligand and the corresponding metal ions are subjected to coordination, and then the brand new imidazolecarboxylic acid complex is obtained. The synthesis method is simple, convenient to operate, safe, mild in reaction condition, high in yield and purity and beneficial for subsequent testing.

The invention provides a synthesis method of tetracarboxylic dianhydride with a fluorinated rigid structure. According to the method, trifluoromethanesulfonic acid, trifluoroacetic acid and/or sulfuric acid is adopted to replace hydrofluoric acid to serve as a catalyst to achieve conversion from 3,4-dimethylphenol or 3,3',4,4'-tetramethyldiphenyl ether to xanthene tetracarboxylic dianhydride, so that the whole synthesis method has the advantages of being efficient, safe and controllable.

The invention relates to a synthesis method of a GQDs modified ZnO composite nanostructure gas sensitive material for detecting dimethylamine gas. The method comprises the following steps: adding GQDsin different proportions into ZnO nanosheets, and synthesizing to obtain the GQDs-modified ZnO composite nanostructure gas sensitive material, namely GQDs-ZnO. The GQDs-modified ZnO composite nanostructure gas sensitive material provided by the invention has an appropriate porous structure and a relatively high specific surface area, and the synthesis method is green, simple and safe, relativelysimple and convenient in raw material acquisition and relatively high in practical degree. When being used as a gas sensitive material, the invention shows excellent gas sensitive performance at the working temperature of 160 DEG C, shows relatively high sensitivity, relatively high linearity, excellent selectivity and relatively good repeatability on dimethylamine gas, has a gas detection lower limit of 0.1 ppm, and has huge potential in the aspect of dimethylamine gas detection.

The invention discloses a method for preparing an umeclidinium bromide intermediate compound as shown in a formula 3, and further discloses a synthesizing method of umeclidinium bromide. The synthesizing method effectively avoids unstable phenyl lithium with high price and toxicity, corresponding quinuclidine building reaction steps are omitted, reaction steps are greatly decreased, and reaction efficiency and yield are improved. The synthesizing method is shorter in reaction step, mild in operation condition, high in safety, low in environmental pollution and higher in yield, and a good basisis provided for industrial amplification of the umeclidinium bromide.

The invention relates to an environment-friendly synthesis method of nitrate, which comprises the following steps: adding organic acid and nitric acid used as catalysts into a nitration kettle according to preset percents to form a mixture, wherein the inside of the nitration kettle is in a nitrogen protective atmosphere, and the reaction temperature inside the nitration kettle is controlled at 25-50 DEG C; and dropwisely adding alkyl alcohol into the mixture to carry out nitration, thereby obtaining the nitrate. The method can effectively overcome the defects of difficulty in waste acid after-treatment, long production process, inapplicability to nitration of water-sensitive and acid-sensitive substances, higher production cost, low atomic economical efficiency, poor selectivity, difficulty in product separation, severe environmental pollution and poor adaptability to raw materials.

The invention discloses a hydrogen evolution catalyst with a nickel hydroxide layer coated elemental ruthenium structure and a preparation method thereof. The catalyst comprises nickel hydroxide and ruthenium, elemental ruthenium is anchored on the surface of foamed nickel and is coated with a nickel hydroxide layer, and ruthenium chloride hydrate and foamed nickel are added into a sodium hydroxide solution to directly synthesize the required catalyst in a homogeneous reactor in a one-step hydrothermal mode. The nickel hydroxide nano sheet and the elemental ruthenium grow on the surface of thefoamed nickel in-situ, so that the use of an additional adhesive is avoided, the good conductivity and mechanical stability are ensured, and the catalytic performance of the catalyst in an alkaline environment is improved by utilizing the synergistic effect between the bi-functional active sites of nickel hydroxide and ruthenium; when the current density of the prepared catalyst in a 1.0 M KOH electrolyte solution is 10 mA.cm<-2>, the required over potential is 27.56 mV (vs RHE).

The invention discloses a method for introducing fluorine ions into ZnMoO4 by a hydrothermal method. The method comprises the following steps: a, weighing molybdenum trioxide, dissolving themolybdenumtrioxide in deionized water, weighing zinc fluoride tetrahydrate, and adding into the obtained aqueous molybdenum trioxide solution; b, transferring a mixed solution obtained in step a into a reaction kettle, and carrying out a hydrothermal reaction for 12-24 hours at the temperature of 200-201 DEG C to obtain a yellow product; and c, repeatedly and centrifugally washing the yellow product obtained in step b with deionized water and ethanol, carrying out vacuum drying for 6-12 hours at the temperature of 50-80 DEG C, and grinding into powder to obtain ZnMoO4: F. According to the ZnMoO4: F material prepared by the invention, XPS, TG and the like prove that a certain amount of fluorine ions exist in crystal lattices, and the ZnMoO4: F material has visible light adsorption. The method disclosed by the invention exceeds the traditional method for preparing the fluorine-containing compound by using dangerous reactants such as HF and PVDF, and is a non-toxic and simple preparation method.