A thermosensitive hydrogel that can be used as a nutritional mask and its preparation method

A temperature-sensitive hydrogel and facial mask technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of difficult synthesis of cosmetic hydrogels with stable properties, human and environmental pollution and damage, and difficulties in chemical crosslinking, etc. problem, achieve good skin care effect, strong preparation ability, and simple synthesis and preparation process

Inactive Publication Date: 2014-10-08
INST OF NUCLEAR PHYSICS & CHEM CHINA ACADEMY OF
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, many commonly used cross-linking agents are toxic to the human body and the environment.
In the selection of hydrogel raw materials, natural polymer materials have become research hotspots because of their good biocompatibility, wide range of sources, large-scale regeneration, degradable by bacteria, and not easy to cause white pollution. Molecular materials such as polysaccharides and proteins are difficult to chemically cross-link, and it is difficult to synthesize stable cosmetic hydrogels
Because of the strong activity of synthetic polymers, it is easy to synthesize hydrogels under the action of cross-linking agents, so synthetic polymers are often used as raw materials for hydrogels, but a large part of synthetic polymers are toxic to the human body and the environment, and are easily harmful to the human body and the environment. cause pollution and damage

Method used

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  • A thermosensitive hydrogel that can be used as a nutritional mask and its preparation method
  • A thermosensitive hydrogel that can be used as a nutritional mask and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0043] Under normal temperature and pressure, dissolve gelatin, sodium carboxymethylcellulose, carboxylated chitosan, and collagen in water according to the components specified in Table 1, and stir to form a uniform solution or emulsion. Prepare molds of different shapes and thicknesses. The raw material solution is poured into the mold, packaged and molded, and placed in an irradiation chamber to irradiate 15 kGy to 60 kGy to synthesize a hydrogel.

[0044] figure 1 It is a photo of an application example of the present invention, a photo of a temperature-sensitive hydrogel that can be used as a nutritional mask prepared by the present invention and applied on the hand. The hydrogel manufacturing mold is round and has a thickness of 3mm.

[0045] figure 2 It is a photo of another application example of the present invention. A photo of a temperature-sensitive hydrogel that can be used as a nutritional mask prepared by the invention and applied on hands.

Embodiment 2

[0047] The method of Example 1 was repeated with the contents of each component specified in Table 1 below, but the selected components and their weight contents were different.

Embodiment 3

[0049] The method of Example 1 was repeated with the contents of each component specified in Table 1 below, but the selected components and their weight contents were different.

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Abstract

The invention provides a thermosensitive hydrogel capable of being used as a nutrition mask and a preparation method of the thermosensitive hydrogel and belongs to the field of natural polymer material biological application. According to the thermosensitive hydrogel, good-biocompatibility natural polymer materials of agar, gelatin, sodium carboxymethylcellulose, chitosan, derivatives of the chitosan, alginic acid, derivatives of the aloginic acid, collagen, hyaluronic acid, derivatives of the hyaluronic acid, glycerol and the like are used as hydrogel raw materials, proportionally dissolved in water, stirred to form a uniform solution or an emulsion, poured into a mask mold, and then placed in a 60Co-gamma industrial irradiation device to be irradiated with the adsorbed dose of 5kGy-60kGy to synthesize the thermosensitive hydrogel. The preparation method is simple, heating is not required, and the raw materials are not required to be specially treated before irradiation. The thermosensitive hydrogel is good in biocompatibility, water-soluble skin nutrition materials can be accordingly released, and good skin care effects are achieved.

Description

technical field [0001] The invention relates to a temperature-sensitive hydrogel that can be used as a nutritional facial mask and a preparation method thereof, which is a hydrogel synthesized from natural polymer materials and belongs to the field of cosmetic application of natural polymer materials. Background technique [0002] At present, the popular beauty masks in the market are mainly based on non-woven fabrics, paper, and cotton cloth, and are formed by impregnating mask liquid. They can be used directly. When using, they can be directly attached to a certain part of the body. The mask liquid acts on human skin, promotes skin blood circulation, enhances the vitality of epidermal cells, moisturizes and nourishes the skin, and achieves the effect of improving skin quality. But use non-woven fabric, paper, cotton cloth etc. as facial mask base material, except playing carrier effect, do not possess cosmetic effect. Because non-woven fabrics, paper, cotton cloth and oth...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/97A61K8/02A61Q19/00A61K8/34A61K8/65
Inventor 杨桂霞安友刘许强俞祥忠曾凡松庞元龙黄玮李宗军蒋树斌李晓燕伍晓利
Owner INST OF NUCLEAR PHYSICS & CHEM CHINA ACADEMY OF
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