483results about How to "Long retention time" patented technology

A memory device including first to fourth memory cell arrays and a driver circuit including a pair of bit line driver circuits and a pair of word line driver circuits is provided. The first to fourth memory cell arrays are overlap with the driver circuit. Each of the pair of bit line driver circuits and a plurality of bit lines are connected through connection points on an edge along the boundary between the first and second memory cell arrays or on an edge along the boundary between the third and fourth memory cell arrays. Each of the pair of word line driver circuits and a plurality of word lines are connected through second connection points on an edge along the boundary between the first and fourth memory cell arrays or on an edge along the boundary between the second and third memory cell arrays.

The present invention relates to Fc-IL-15 hybrids, which may or may not include peptide linkers between the IL-15 and the Fc portion, for methods of treatment of tumors and viral infections. The IL-15 hybrids can be Fc-IL-15 or IL-15-Fc hybrids. The Fc-IL-15 hybrids include variants, including the IL-15 and Fc variants. The hybrids preferably (but not necessarily) include peptide linkers between the IL-15 and the Fc portion. These linkers are preferably composed of a T cell inert sequence, or any non-immunogenic sequence.

The invention relates to a mosquito repelling preparation, in particular to a natural plant essential oil composition capable of directly serving as a mosquito repellent. The problems of short persistence time, a poor mosquito repelling effect, side effects on human bodies and the like of the traditional mosquito repellent are solved. The natural plant essential oil composition is prepared from the following components in percentage by weight: 5 to 10 percent of lavender oil, 2 to 8 percent of lemongrass oil, 2 to 5 percent of basil oil, 2 to 10 percent of chamomile oil, 1.5 to 5 percent of peppermint oil, 1 to 10 percent of eucalyptus oil, 2 to 10 percent of tea tree oil, 1 to 4 percent of citronella oil, 1 to 2 percent of thyme oil, 1 to 10 percent of glycerol, 1 to 20 percent of ethanol and the balance of diluent, namely deionized water. The natural plant essential oil composition naturally diffuses fragrance, has a mosquito repelling effect, is safe and nontoxic, is long in storage time, has swelling dispelling, itching relieving and sterilizing effects, does not have any side effect on the human bodies and is convenient to use. Tests show that the mosquito repelling effect can be over 90 percent averagely.

A semiconductor device capable of realizing low-voltage drivability and large storage capacity (miniaturization) by achieving large threshold voltage shifts and long retention time while at the same time suppressing variations in characteristics among memory cells is disclosed. The device includes a semiconductor memory cell having a channel region formed in a semiconductor substrate, a tunnel insulator film on the channel region, a charge storage insulator film on the tunnel insulator film, a control dielectric film on the charge storage film, a control electrode on the control dielectric film, and source/drain regions at opposite ends of the channel region. The memory cell's channel region has a cross-section at right angles to a direction along the channel length, the width W and height H of which are each less than or equal to 10 nm.

A dynamic random access memory structure having a vertical floating body cell includes a semiconductor substrate having a plurality of cylindrical pillars, an upper conductive region positioned on a top portion of the cylindrical pillar, a body positioned below the upper conductive portion in the cylindrical pillar, a bottom conductive portion positioned below the body in the cylindrical pillar, a gate oxide layer surrounding the sidewall of the cylindrical pillar and a gate structure surrounding the gate oxide layer. The upper conductive region serves as a drain electrode, the bottom conductive region serves as a source electrode and the body can store carriers such as holes. Preferably, the dynamic random access memory structure further comprises a conductive layer positioned on the surface of the semiconductor substrate to electrically connect the bottom conductive regions in the cylindrical pillars.

The invention belongs to the technical field of trace amount detection, in particular relates to a method that surfaces functionalized nanogold particles are used for potential fingerprint appearance. The invention provides the method that the different surface functionalized nanogold particles (probe) are used for the potential fingerprint appearance. The particles are the hydrophobixated nanogold particles decorated by alkyl hydrosulfide, the hydrophobixated nanogold particles protected by surface active agent cetane trimethyl ammonium bromide (CTAB), the water-soluble nanogold particles protected by the CTAB and the water-soluble nanogold particles protected by L-cysteine respectively. The probe and the ingredients in the residual sweat in the potential fingerprint generate the absorption and static functions or the condensation reaction, then an argentation is utilized to lead potential fingerprint samples to colorate in the argentation liquid, the nanogold particle signals for the ingredient identification in the fingerprint are magnified and the reduced argentum particles deposite at the grain position of the fingerprint samples to further present black, thereby forming the clear fingerprint image that can be observed by naked eyes. The method is simple, fast and high in sensitivity and has no harmful side effects.

Novel exendins with modifications at one or more of following positions: 2, 14, 27 or 28 and polyethylene glycol derivatives thereof are provided. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

Sulfur emissions from combustion of coal and other fuels are reduced by using sugar beet lime as a sorbent during the coal burning process. In various embodiments, the sugar beet lime is added onto the coal before combustion, along with the coal into the furnace, is injected directly into the fire coal, or is added into the flue gases downstream of the furnace. The relatively high calcium content of the sugar beet lime leads to efficient sulfur capture at suitably low treat levels. Excess ash is avoided in the process.

To achieve a stable reading operation in a memory cell having a gain-cell structure, a write transistor is configured, which has a source and a drain that are formed on the insulating layer, a channel formed on the insulating layer and between the source and the drain and made of a semiconductor, and a gate formed on an upper portion of the insulating layer and between the source and the drain and electrically insulated from the channel by a gate insulating film and controlling the potential of the channel. The channel electrically connects the source and the drain on the side surfaces of the source and the drain.

An one-transistor random access memory device integrated on a silicon-on-insulator (SOI) substrate has a capacitor structure buried in at least part of a capacitor trench in the SOI substrate, and a gate structure formed on the SOI substrate. A top electrode the capacitor structure is formed simultaneously with and of the same conductive material as a gate electrode of the gate structure. A capacitor dielectric layer of the capacitor structure is formed simultaneously with and of the same dielectric material as a gate dielectric layer of the gate structure.

Strip-shaped forms of administration for administering an active ingredient via the mucous membrane of the gums.

The invention provides a crosslinking hyaluronic acid gel and its preparation method. The method is characterized in that divinylsulfone is combined with polyethylene glycol for generating a novel cross-linking agent at first, the novel cross-linking agent is reacted with a hyaluronic acid molecule for producing a crosslinking hyaluronic acid gel. The crosslinking sodium hyaluronate gel obtained in the invention has good biological compatibility and longer half life period, and the particle is small and uniform, and is suitable for beautifying shaping, tissue filling, bone articular lubrication or medicine sustained-release preparation and the like.

FRAM includes a tunable gain amp serving as a local sense amp, wherein the tunable gain amp is connected to a local bit line for reading a memory cell including a pass transistor and a ferroelectric capacitor, and gain is adjusted by setting a local amp voltage for reading the memory cell more effectively with optimized gain. And a global sense amp is connected to the local sense amp for receiving a read output. When reading data, a voltage difference in the local bit line is converted to a time difference by the sense amps for differentiating high data and low data. For example, high data is quickly transferred to an output latch circuit through the sense amps with high gain, but low data is rejected by a locking signal based on high data as a reference signal. Additionally, alternative circuits and memory cell structures for implementing the memory are described.

The invention relates to a hydrogen-enriched health beverage. The hydrogen-enriched health beverage contains drinking water, and hydrogen and water soluble plant extracts containing natural small molecular group substances are added, wherein mass concentration of the water soluble plant extracts ranges from 3 to 250000ppm, and mass concentration of hydrogen ranges from 0.6 to 3ppm. A preparation method comprises following steps: A, the water soluble plant extracts containing natural small molecular group substances are extracted from plant and are added into drinking water, and an obtained solution is stirred to be uniform; B, hydrogen is added so as to obtain the hydrogen-enriched health beverage. Compared with the prior art, the preparation method is capable of realizing dissolving of the water soluble plant extracts and hydrogen at the same time, solubility of hydrogen in water is increased greatly, release of hydrogen from water is not easily caused, retention time of hydrogen in the hydrogen-enriched health beverage is prolonged, beverage oxidation is delayed, stability is improved, and shelf life is prolonged; synergistic effect of the plant extracts with hydrogen is achieved, so that health protection effect of hydrogen is improved, health protection effect and dietary therapy effect of the water soluble plant extracts are improved, and the effect achieved via combination of two ingredients is better than the sum of the effects of the two ingredients.

The invention relates to cross-linked sodium hyaluronate and a preparation method and application thereof. The cross-linked sodium hyaluronate is prepared from raw materials, including sodium hyaluronate, an inorganic salt and a cross-linking agent. The preparation method comprises the steps: dissolving a certain amount of sodium hyaluronate in an alkaline solution with the pH value of 7.5 to 9.0, then, adding a certain amount of inorganic salt into the solution, and carrying out stirring until the inorganic salt is completely dissolved; heating the solution to the temperature of 20 DEG C to 60 DEG C, then, slowly dripping a certain volume of cross-linking agent solution into the solution, carrying out stirring, and carrying out a reaction for a period of time while carrying out heat preservation; adjusting the pH to 7.1 to 7.5 with acid, carrying out balancing for 1 to 2 hours, then, carrying out precipitation with ethanol or an ethanol solution, so as to obtain lumpy solids, i.e., the cross-linked sodium hyaluronate. By the method provided by the invention, the cross-linking efficiency of the cross-linked sodium hyaluronate can be increased, the reaction yield can be increased, side reactions can be reduced, and the residual of the cross-linking agent can be reduced; the prepared cross-linked sodium hyaluronate is safe and non-toxic, is good in stability, long in in-vivo retention time and good in filling effect and is applicable to in-vivo injection.

The present invention discloses a modified exendin or pharmaceutically acceptable salts thereof, wherein the modified exendin comprises an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17 and the amino acid sequence has a higher stability than the non-modified exendin of SEQ ID No. 4. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

The invention discloses application of rhodamine B derivatives, and relates to application of rhodamine B derivatives provided with intra-molecular spiral rings and used as cell lysosome fluorescent colorants. The rhodamine B derivatives are rhodamine B derivatives with intra-molecular five-member rings; and the rhodamine B derivatives can be used as the cell lysosome fluorescent colorants and used for high-selectivity and long-term stably labeled cell lysosome. The application has the advantages that: (1) the amino-containing rhodamine B derivatives with intra-molecular five-member rings can be used as lysosome fluorescent labeling substances of cells of different types; (2) the rhodamine B derivatives have long retention time in cells and high light stability; and (3) the rhodamine B derivatives can be used for labeling and tracking intra-molecular lysosome for long time.

The invention discloses pemetrexed disodium liposome injection which is mainly made of pemetrexed disodium and a preparation method thereof, distearoyl phosphatidyl glycerol, dipalmitoyl phosphatidyl choline, PEG600, cholesterol and mannitol. The liposome injection has the advantages that the particle size of liposome is small, the liposome is uniformly distributed, the encapsulation efficiency is high, the leakage rate is low, the stability is good, the solubility of the pemetrexed disodium and the quality of injection products are improved, the toxic and side effect is reduced, and the curative effect is improved.

Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion/spheronization.