483results about How to "Long retention time" patented technology

A capacitor memory is realized, wherein a capacitor stores data and a diode controls to store data “1” or “0”. Diode has four terminals wherein first terminal serves as word line, second terminal serves as storage node, third terminal is floating, and fourth terminal serves as bit line, wherein back channel effect is suppressed adding additional ions in the bottom side of third terminal or applying negative voltage in the well or substrate. A capacitor plate couples to second terminal, which plate has no coupling region to first, third and fourth terminal. With no coupling, the inversion layer of plate in the storage node is isolated from the adjacent nodes. In doing so, the plate can swing ground level to positive supply level to write. As a result, no negative generator is required for controlling plate. Word line and bit line keep ground level during standby, and rise to supply level for read or write operation. In this manner, no holding current is required during standby, and operating current is dramatically reduced with no negative generator. Write has a sequence to clear the state of cell before writing to store data regardless of previous state. Refresh cycle is periodically asserted to sustain data. The present invention can be applied for destructive read, or for nondestructive read adding pull-down device to bit line. The height of cell is almost same as control circuit on the bulk or SOI wafer.

A memory device including first to fourth memory cell arrays and a driver circuit including a pair of bit line driver circuits and a pair of word line driver circuits is provided. The first to fourth memory cell arrays are overlap with the driver circuit. Each of the pair of bit line driver circuits and a plurality of bit lines are connected through connection points on an edge along the boundary between the first and second memory cell arrays or on an edge along the boundary between the third and fourth memory cell arrays. Each of the pair of word line driver circuits and a plurality of word lines are connected through second connection points on an edge along the boundary between the first and fourth memory cell arrays or on an edge along the boundary between the second and third memory cell arrays.

The present invention relates to Fc-IL-15 hybrids, which may or may not include peptide linkers between the IL-15 and the Fc portion, for methods of treatment of tumors and viral infections. The IL-15 hybrids can be Fc-IL-15 or IL-15-Fc hybrids. The Fc-IL-15 hybrids include variants, including the IL-15 and Fc variants. The hybrids preferably (but not necessarily) include peptide linkers between the IL-15 and the Fc portion. These linkers are preferably composed of a T cell inert sequence, or any non-immunogenic sequence.

The invention relates to a mosquito repelling preparation, in particular to a natural plant essential oil composition capable of directly serving as a mosquito repellent. The problems of short persistence time, a poor mosquito repelling effect, side effects on human bodies and the like of the traditional mosquito repellent are solved. The natural plant essential oil composition is prepared from the following components in percentage by weight: 5 to 10 percent of lavender oil, 2 to 8 percent of lemongrass oil, 2 to 5 percent of basil oil, 2 to 10 percent of chamomile oil, 1.5 to 5 percent of peppermint oil, 1 to 10 percent of eucalyptus oil, 2 to 10 percent of tea tree oil, 1 to 4 percent of citronella oil, 1 to 2 percent of thyme oil, 1 to 10 percent of glycerol, 1 to 20 percent of ethanol and the balance of diluent, namely deionized water. The natural plant essential oil composition naturally diffuses fragrance, has a mosquito repelling effect, is safe and nontoxic, is long in storage time, has swelling dispelling, itching relieving and sterilizing effects, does not have any side effect on the human bodies and is convenient to use. Tests show that the mosquito repelling effect can be over 90 percent averagely.

A semiconductor device capable of realizing low-voltage drivability and large storage capacity (miniaturization) by achieving large threshold voltage shifts and long retention time while at the same time suppressing variations in characteristics among memory cells is disclosed. The device includes a semiconductor memory cell having a channel region formed in a semiconductor substrate, a tunnel insulator film on the channel region, a charge storage insulator film on the tunnel insulator film, a control dielectric film on the charge storage film, a control electrode on the control dielectric film, and source / drain regions at opposite ends of the channel region. The memory cell's channel region has a cross-section at right angles to a direction along the channel length, the width W and height H of which are each less than or equal to 10 nm.

A dynamic random access memory structure having a vertical floating body cell includes a semiconductor substrate having a plurality of cylindrical pillars, an upper conductive region positioned on a top portion of the cylindrical pillar, a body positioned below the upper conductive portion in the cylindrical pillar, a bottom conductive portion positioned below the body in the cylindrical pillar, a gate oxide layer surrounding the sidewall of the cylindrical pillar and a gate structure surrounding the gate oxide layer. The upper conductive region serves as a drain electrode, the bottom conductive region serves as a source electrode and the body can store carriers such as holes. Preferably, the dynamic random access memory structure further comprises a conductive layer positioned on the surface of the semiconductor substrate to electrically connect the bottom conductive regions in the cylindrical pillars.

The invention belongs to the technical field of trace amount detection, in particular relates to a method that surfaces functionalized nanogold particles are used for potential fingerprint appearance. The invention provides the method that the different surface functionalized nanogold particles (probe) are used for the potential fingerprint appearance. The particles are the hydrophobixated nanogold particles decorated by alkyl hydrosulfide, the hydrophobixated nanogold particles protected by surface active agent cetane trimethyl ammonium bromide (CTAB), the water-soluble nanogold particles protected by the CTAB and the water-soluble nanogold particles protected by L-cysteine respectively. The probe and the ingredients in the residual sweat in the potential fingerprint generate the absorption and static functions or the condensation reaction, then an argentation is utilized to lead potential fingerprint samples to colorate in the argentation liquid, the nanogold particle signals for the ingredient identification in the fingerprint are magnified and the reduced argentum particles deposite at the grain position of the fingerprint samples to further present black, thereby forming the clear fingerprint image that can be observed by naked eyes. The method is simple, fast and high in sensitivity and has no harmful side effects.

The invention relates to the technical field of medicines, and in particular relates to a micro-emulsion thermosensitive gel for skin wound healing and a preparation method thereof. The micro-emulsion thermosensitive gel disclosed by the invention is composed of medicines, oil phase, a surfactant, a cosurfactant, a gel matrix and water, wherein the medicines are selected from resveratrol, paeonol and matrine. Proved by animal experiments, the prepared micro-emulsion thermosensitive gel has the characteristics of nearly no irritation to skin, safety in use, large percutaneous infiltration quantity, high percutaneous infiltration rate, long retention time of the micro-emulsion gel in the skin, high medicine concentration in the skin, good slow-release effect and good effect of promoting the healing of skin wound injury. The micro-emulsion thermosensitive gel disclosed by the invention has the advantages of simpleness in preparation method, low cost, convenience and safety in use and capability of effectively promoting the skin wound healing. According to the invention, a novel dosage form is provided for treating the skin wound.

Novel exendins with modifications at one or more of following positions: 2, 14, 27 or 28 and polyethylene glycol derivatives thereof are provided. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

Sulfur emissions from combustion of coal and other fuels are reduced by using sugar beet lime as a sorbent during the coal burning process. In various embodiments, the sugar beet lime is added onto the coal before combustion, along with the coal into the furnace, is injected directly into the fire coal, or is added into the flue gases downstream of the furnace. The relatively high calcium content of the sugar beet lime leads to efficient sulfur capture at suitably low treat levels. Excess ash is avoided in the process.

To achieve a stable reading operation in a memory cell having a gain-cell structure, a write transistor is configured, which has a source and a drain that are formed on the insulating layer, a channel formed on the insulating layer and between the source and the drain and made of a semiconductor, and a gate formed on an upper portion of the insulating layer and between the source and the drain and electrically insulated from the channel by a gate insulating film and controlling the potential of the channel. The channel electrically connects the source and the drain on the side surfaces of the source and the drain.

A capacitor memory is realized, wherein a capacitor stores data and a diode controls to store data “1” or “0”. Diode has four terminals wherein first terminal serves as word line, second terminal serves as storage node, third terminal is floating, fourth terminal serves as bit line, at least one of the terminals is formed vertically, which diode is formed from silicon, metal or compound materials. The cell is isolated from well or substrate, and the height of cell is close to that of control circuit. A capacitor plate couples to second terminal, which plate has no coupling region to first, third and fourth terminal. With no coupling, the inversion layer of plate in the storage node is isolated from the adjacent nodes. In doing so, the plate can swing ground level to positive supply level to write. As a result, no negative generator is required for controlling plate. Word line and bit line keep ground level during standby, and rise to supply level for read or write operation. In this manner, no holding current is required during standby, and operating current is dramatically reduced with no negative generator. Write has a sequence to clear the state of cell before writing to store data regardless of previous state. Refresh cycle is periodically asserted to sustain data. The present invention can be applied for destructive read, or for nondestructive read adding pull-down device to bit line.

An one-transistor random access memory device integrated on a silicon-on-insulator (SOI) substrate has a capacitor structure buried in at least part of a capacitor trench in the SOI substrate, and a gate structure formed on the SOI substrate. A top electrode the capacitor structure is formed simultaneously with and of the same conductive material as a gate electrode of the gate structure. A capacitor dielectric layer of the capacitor structure is formed simultaneously with and of the same dielectric material as a gate dielectric layer of the gate structure.

The invention discloses a micron and nanoscale cosmetic and plastic filling particle made of poly-d-lactic acid macromolecule resin and a preparation method thereof. The size of the particle is 50-0.45micron. The freeze-dried powder of the particle is suspended in water, and then is injected into a loose or wrinkled facial tissue by an injector so as to achieve the purpose of plastic surgery. The particle contains compound amino acid and is prepared by a mechanical method or an emulsification method. The mechanical method comprises the following steps: suspending the amino acid into a polymer solution, removing a mixture of the dried solvent, extruding into strips, and smashing at low temperature into micro-nano particles; and the emulsification method comprises the following steps: emulsifying an amino acid water solution into a polymer organic solution to form a first emulsion, then emulsifying the emulsion into another water solution so as to obtain a multiple emulsion, and removing the organic solvent to obtain micro-nano particles. The micro-nano particle containing compound amino acid prepared by the two methods is sieved and then suspended in the water solution with a frozen support again, and after freeze drying is finished, the product is obtained.

Strip-shaped forms of administration for administering an active ingredient via the mucous membrane of the gums.

The present invention discloses a teaching quality assessment system based on big data. The system comprises a student terminal-score analysis module, a teacher terminal-score analysis module, a school terminal-teaching quality analysis module and an education bureau terminal-teaching quality analysis module; the teacher terminal-score analysis module is configured for teachers to perform browsing and analysis of the administered class test scores; the school terminal-teaching quality analysis module is configured for school administrators to perform browsing and analysis of the administered class test scores; and the education bureau terminal-teaching quality analysis module is configured to the education bureau managers to perform browsing and analysis of the administered region school test scores. Through the analysis of test scores each time, the teaching quality assessment system based on big data can obtain each layer of score dimension reports which are displayed for each role, and carries out each comparison mode to provide reliable scientific basis for improvement of the teaching level assessment through lateral comparison and vertical comparison.

The invention discloses an anti-halitosis toothpaste containing natural drug compound components, and aims to provide a toothpaste which is capable of effectively inhibiting halitosis pathogens in the oral cavity and efficiently eliminating halitosis, takes natural Chinese herbal medicines as components for eliminating halitosis, and is safe and healthy. The anti-halitosis toothpaste containing the natural drug compound components is composed of toothpaste base materials and an active component compound, wherein the content of the active component compound is 0.601-5.9% in percentage by weight and the balance is the toothpaste base materials; and the active component compound is composed of tea polyphenol, vitamin C, zinc citrate, triclosan and sodium alginate.

A ferroelectric capacitor and a method for manufacturing the same includes a lower electrode, a dielectric layer, and an upper electrode layer, which are sequentially stacked, wherein the dielectric layer has a multi-layer structure including a plurality of sequentially stacked ferroelectric films, and wherein two adjacent ferroelectric films have either different compositions or different composition ratios. Use of a ferroelectric capacitor according to an embodiment of the present invention, it is possible to hold stable polarization states of ferroelectric domains for a long retention time, and thus data written in the ferroelectric capacitor a long time ago can be accurately written, thereby improving the reliability of a ferroelectric random access memory (FRAM).

The invention provides a crosslinking hyaluronic acid gel and its preparation method. The method is characterized in that divinylsulfone is combined with polyethylene glycol for generating a novel cross-linking agent at first, the novel cross-linking agent is reacted with a hyaluronic acid molecule for producing a crosslinking hyaluronic acid gel. The crosslinking sodium hyaluronate gel obtained in the invention has good biological compatibility and longer half life period, and the particle is small and uniform, and is suitable for beautifying shaping, tissue filling, bone articular lubrication or medicine sustained-release preparation and the like.

The invention belongs to the technical field of detection, and in particular relates to a method for applying ZnS, ZnO and functionalized nano granules thereof in revealing latent fingerprints on different surfaces. The invention provides a method for revealing latent fingerprints on surfaces including glass, plastics, metal, clad plate (lacquer wood), paper and the like by means of ZnS, ZnO and functionalized nano granules thereof, wherein ZnS is prepared by two methods of a grinding method and a solution method, while ZnO nano powder is prepared by a sol-gel method; during revealing, the method for revealing the latent fingerprints on different object surfaces is realized by means of a dry powder brushing revealing method and a wet revealing method. The method has the advantages of simplicity, quickness, easy operation, no toxic and side effects on an operator and visualized result.

FRAM includes a tunable gain amp serving as a local sense amp, wherein the tunable gain amp is connected to a local bit line for reading a memory cell including a pass transistor and a ferroelectric capacitor, and gain is adjusted by setting a local amp voltage for reading the memory cell more effectively with optimized gain. And a global sense amp is connected to the local sense amp for receiving a read output. When reading data, a voltage difference in the local bit line is converted to a time difference by the sense amps for differentiating high data and low data. For example, high data is quickly transferred to an output latch circuit through the sense amps with high gain, but low data is rejected by a locking signal based on high data as a reference signal. Additionally, alternative circuits and memory cell structures for implementing the memory are described.

The invention relates to a hydrogen-enriched health beverage. The hydrogen-enriched health beverage contains drinking water, and hydrogen and water soluble plant extracts containing natural small molecular group substances are added, wherein mass concentration of the water soluble plant extracts ranges from 3 to 250000ppm, and mass concentration of hydrogen ranges from 0.6 to 3ppm. A preparation method comprises following steps: A, the water soluble plant extracts containing natural small molecular group substances are extracted from plant and are added into drinking water, and an obtained solution is stirred to be uniform; B, hydrogen is added so as to obtain the hydrogen-enriched health beverage. Compared with the prior art, the preparation method is capable of realizing dissolving of the water soluble plant extracts and hydrogen at the same time, solubility of hydrogen in water is increased greatly, release of hydrogen from water is not easily caused, retention time of hydrogen in the hydrogen-enriched health beverage is prolonged, beverage oxidation is delayed, stability is improved, and shelf life is prolonged; synergistic effect of the plant extracts with hydrogen is achieved, so that health protection effect of hydrogen is improved, health protection effect and dietary therapy effect of the water soluble plant extracts are improved, and the effect achieved via combination of two ingredients is better than the sum of the effects of the two ingredients.

The invention relates to a porous crosslinked polystyrene microsphere which has a surface micropore and internal macropore structure. Particularly, the mean pore size of surface micropores is 18.64-22.82nm, and the mean pore size of internal macropores is 0.75-1.64 micrometers. When the porous crosslinked polystyrene microsphere with the structure serves as chromatographic column filling, the column pressure can be effectively reduced; the internal macropore structure further increases action area between a detected substance and the microsphere; the retention time is prolonged; and substance separation can be better achieved.

Novel exendins with modifications at one or more of following positions: 2, 14, 27 or 28 and polyethylene glycol derivatives thereof are provided. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

The invention relates to cross-linked sodium hyaluronate and a preparation method and application thereof. The cross-linked sodium hyaluronate is prepared from raw materials, including sodium hyaluronate, an inorganic salt and a cross-linking agent. The preparation method comprises the steps: dissolving a certain amount of sodium hyaluronate in an alkaline solution with the pH value of 7.5 to 9.0, then, adding a certain amount of inorganic salt into the solution, and carrying out stirring until the inorganic salt is completely dissolved; heating the solution to the temperature of 20 DEG C to 60 DEG C, then, slowly dripping a certain volume of cross-linking agent solution into the solution, carrying out stirring, and carrying out a reaction for a period of time while carrying out heat preservation; adjusting the pH to 7.1 to 7.5 with acid, carrying out balancing for 1 to 2 hours, then, carrying out precipitation with ethanol or an ethanol solution, so as to obtain lumpy solids, i.e., the cross-linked sodium hyaluronate. By the method provided by the invention, the cross-linking efficiency of the cross-linked sodium hyaluronate can be increased, the reaction yield can be increased, side reactions can be reduced, and the residual of the cross-linking agent can be reduced; the prepared cross-linked sodium hyaluronate is safe and non-toxic, is good in stability, long in in-vivo retention time and good in filling effect and is applicable to in-vivo injection.

The present invention discloses a modified exendin or pharmaceutically acceptable salts thereof, wherein the modified exendin comprises an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17 and the amino acid sequence has a higher stability than the non-modified exendin of SEQ ID No. 4. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

The present invention discloses a modified exendin or pharmaceutically acceptable salts thereof, wherein the modified exendin comprises an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17 and the amino acid sequence has a higher stability than the non-modified exendin of SEQ ID No. 4. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

The invention discloses application of rhodamine B derivatives, and relates to application of rhodamine B derivatives provided with intra-molecular spiral rings and used as cell lysosome fluorescent colorants. The rhodamine B derivatives are rhodamine B derivatives with intra-molecular five-member rings; and the rhodamine B derivatives can be used as the cell lysosome fluorescent colorants and used for high-selectivity and long-term stably labeled cell lysosome. The application has the advantages that: (1) the amino-containing rhodamine B derivatives with intra-molecular five-member rings can be used as lysosome fluorescent labeling substances of cells of different types; (2) the rhodamine B derivatives have long retention time in cells and high light stability; and (3) the rhodamine B derivatives can be used for labeling and tracking intra-molecular lysosome for long time.

The invention discloses pemetrexed disodium liposome injection which is mainly made of pemetrexed disodium and a preparation method thereof, distearoyl phosphatidyl glycerol, dipalmitoyl phosphatidyl choline, PEG600, cholesterol and mannitol. The liposome injection has the advantages that the particle size of liposome is small, the liposome is uniformly distributed, the encapsulation efficiency is high, the leakage rate is low, the stability is good, the solubility of the pemetrexed disodium and the quality of injection products are improved, the toxic and side effect is reduced, and the curative effect is improved.

Vaginal use compositions comprising pellets prepared from a debranched starch. Pellets may be conveniently prepared via extrusion / spheronization.