A compound composition for preventing and treating shrimp hepatocellular carcinoma and its preparation method

The combination of albendazole, ivermectin, and glycyrrhizic acid monoammonium salt has solved the treatment problem of shrimp hepatocystis disease, achieving safe and efficient prevention and control, reducing the pathogen load of shrimp hepatocystis, and ensuring aquaculture benefits.

CN122320980APending Publication Date: 2026-07-03HEBEI MEIHE PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-30
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

Current technology has not yet found a cheap, safe, and effective drug to treat shrimp hepatic cysticercosis. Furthermore, shrimp hepatic cysticercosis is highly insidious and difficult to detect in its early stages, which affects the profitability of aquaculture.

Method used

A compound composition of albendazole, ivermectin, and glycyrrhizic acid monoammonium salt is used to inhibit the synthesis of microtubule protein in insects, act on the neuromuscular junction to cause paralysis and death of insects, and combine antioxidant, anti-inflammatory and immunomodulatory effects. It is prepared into different dosage forms such as tablets, capsules and granules to suit different drug administration scenarios in aquaculture.

Benefits of technology

It significantly reduces the pathogenic load of EHP in shrimp, reduces the dosage of single-drug treatment and the risk of drug resistance, and ensures the healthy and sustainable development of aquaculture.

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Abstract

This invention relates to the field of veterinary drug technology, and proposes a compound composition for the prevention and treatment of shrimp hepatocellular carcinoma and its preparation method. The compound composition comprises the following raw materials: albendazole, ivermectin, and glycyrrhizic acid monoammonium salt. The components in the compound composition for the prevention and treatment of shrimp hepatocellular carcinoma provided by this invention work synergistically to safely control the disease and ensure the healthy and sustainable development of aquaculture.
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