32 results about "Provitamin" patented technology

The invention discloses a multi-acting-force high-strength polysaccharide-based hydrogel mask which comprises a solution A and a solution B. The solution A comprises 0.3 wt%-4.0 wt% of sodium alginate, 0.5 wt%-2.0 wt% of plant polysaccharide, 0.5 wt%-1.5 wt% of a humectant, 0.1 wt%-0.6 wt% of a barrier repairing agent and 0.5 wt%-1.0 wt% of a thickening agent, and the pH of the solution A is 4.0-6.5. The solution B comprises 50-300 mM of calcium salt, 0.1-5.0 wt% of natural polyphenol, 0.1-5.0 wt% of amino acid and polypeptide raw materials, 0.1-5.0 wt% of provitamin B5 and 0.1-1.0 wt% of sodium hexametaphosphate, and the pH value of the solution B is neutral. According to the invention, a natural polyphenol-calcium ion multiple acting force system is applied to the hydrogel mask for the first time, a three-dimensional network structure is constructed through multiple actions of physical hydrogen bonds / hydrophobic interaction and ionic bonds, the mask is endowed with super-strong adhesiveness, high tensile strength, antioxidant activity and long-acting antibacterial performance, and the hydrogel mask has great popularization and application values.

The invention relates to the technical field of vitamin production, in particular to high-efficiency vitamin production equipment which comprises a bottom plate, a crusher mounted on the bottom plate, an emulsifying tank and a control console fixedly connected to the bottom plate, a suction device assembled on the bottom plate, and a melting device assembled below the suction device. Through cooperation of structures such as the nitrogen generator and the nitrogen tank, the absorption pipe performs directional absorption on crushed materials, so that the materials are driven to flow in a closed environment and are fed into the storage tank connected with the output end of the nitrogen generator, and the materials in the storage tank are discharged through the discharge pipe mounted on one side; the tail end of the discharging pipe is connected with a first corrugated pipe, the first corrugated pipe is flexibly connected to a feeding port of the melting tank, continuous conveying of powder from the suction device to the melting device is achieved, the whole process is completed under nitrogen protection, and oxidation reaction, moisture absorption deterioration or leakage pollution of the powder in the conveying process are avoided; the stability and the transfer efficiency of the vitamin raw materials are improved.

The present invention relates to a novel provitamin B5-based lipid derivative compound, a lipid nanoparticle composition comprising same, and the like. More specifically, the novel provitamin B5-based lipid compound functions as an ionizable lipid in the formation of lipid nanoparticles and forms stable lipid nanoparticles, which can be used for delivering pharmaceutically active ingredients such as mRNA into the body.

The utility model belongs to the technical field of vitamin centrifugal purification, and discloses continuous purification equipment for vitamin B6 production, which comprises a main body, an inlet and outlet groove is arranged on the surface of the main body, a fixed support is arranged on the top surface of the main body, and a filter component for vitamin B6 raw material purification is arranged in the main body. An adjusting assembly used for adjusting the position of the filtering assembly is arranged in the in-out groove, a lifting air cylinder is arranged on the top face of the fixing support, the output end of the lifting air cylinder is fixedly connected with the adjusting assembly, the filtering assembly can be rapidly disassembled and assembled in the device, and replacement of the vitamin B6 raw material is facilitated; the adjusting assembly can adjust the positions of the symmetrical filtering assemblies, when one filtering assembly filters and purifies the raw materials in the main body, the other filtering assembly can prepare the raw materials outside the main body, and due to the design, the device does not need to stop working, and continuous filtering and purification can be carried out; the purification efficiency of the vitamin B6 is improved, and the practicability of the device is improved.

1. Name of the Design Product: Packaging Bag (TIMEE Chamomile Pro-Vitamin B5 Hydrating Mask). 2. Use of the Design Product: For the outer packaging of masks. 3. Design Key Points of the Design Product: Lies in the pattern. 4. Picture or Photograph that Best Illustrates the Design Key Points: Front View. 5. This design product is a thin product, the left view, right view, bottom view, and top view are omitted.

The present invention relates to a liquid composition containing a combination of vitamins A, D, E and K or a suitable provitamin thereof in a liquid matrix, where the total amount of said vitamins and provitamins is at least 0.2% by weight of the total compositions. The invention further relates to the use of this vitamin formulation in the treatment of an existing or impending vitamin deficiency condition concerning at least one of vitamin A, D, E or K, in particular due to vitamin maldigestion. The present invention also relates to formulations for dietary purposes, cosmetic purposes or medical purposes, in particular to dosage forms for oral administration, to formulations for parenteral administration and to topical formulations. The present invention further relates to the use of the compositions for dietary purposes, including e.g. food supplementation and food for special purposes, such as a balanced diet. The present invention further relates to the use of the compositions for medical purposes and for cosmetic purposes.

The invention discloses gynecological antibacterial gel aiming at female HPV (human papillomavirus) and a preparation process thereof. The gynecological antibacterial gel is prepared from the following raw materials in parts by weight: 1 to 5 percent of compound fungal polysaccharide, 0.1 to 1 percent of herba centellae extract, 0.1 to 1 percent of coriolus versicolor extract, 0.1 to 1 percent of green tea extract, 0.1 to 0.8 percent of fucoidan polysaccharide sulfate and 0.1 to 1 percent of ginsenoside rg3. The preservative is prepared from, by weight, 0.1%-1% of ginsenoside rg2, 0.1%-1% of betulin, 0.1%-0.5% of sophora flower bud extract, 0.1%-1% of natural silkworm antibacterial peptide, 0.5%-1% of carbomer, 0.1%-0.2% of chlorhexidine gluconate, 3% of glycerinum, 0.6% of xylooligosaccharide, 0.6% of sodium hyaluronate middle molecules, 1.5% of hydrolyzed beta-glucan, 0.6% of 98% D-panthenol, 0.6% of provitamin B5, 0.3% of vitamin C, 0.3% of sodium ascorbate and the balance deionized water. The invention relates to the technical field of gynecological treatment. The composition contains various natural plant extracts and bioactive components, can effectively improve cervical health, can realize effective integration of a microemulsion system and a water phase system during preparation, forms a uniform and stable final product, protects the active components, and ensures the curative effect and product performance.

The invention belongs to the technical field of experimental animal nutriology and sterile animal culture, and particularly relates to a vitamin compound for prolonging the survival time of sterile zebra fish and a preparation method of the vitamin compound. The vitamin compound is prepared from the following components in parts by mass: 600 to 1000 parts of vitamin A, 4000 to 6000 parts of vitamin C, 10 to 30 parts of vitamin D3, 1500 to 2200 parts of vitamin E, 80 to 120 parts of vitamin K3, 15000 to 25000 parts of compound B vitamins and sterile culture water. The preparation method comprises the following steps: dissolving the vitamin raw materials in sterile culture water, performing ultrasonic assisted dissolution, and then filtering and sterilizing to obtain the vitamin supplement. When the vitamin supplement is used for feeding the sterile zebra fish, the survival time of the sterile zebra fish can be obviously prolonged, and the expression level of growth hormone genes and insulin-like growth factor genes can be up-regulated. The application value of the sterile zebrafish in scientific research is further expanded.

The invention provides continuous flow photochemical reaction equipment and a vitamin D3 stock solution synthesis process thereof.The equipment comprises a tank body, the upper end of the tank body is communicated with a liquid adding pipe and a negative pressure connecting pipe, the lower end of the tank body is communicated with a discharging pipe, a heating cavity is formed in the side wall of the tank body, and a mounting cylinder with an upper opening and a lower opening is arranged in the tank body; a plurality of ultraviolet lamps are mounted on the front side and the rear side of each vertical mounting strip. A circulating irradiation channel is arranged between the inner wall of the heating cavity in the tank body and the outer wall of the mounting cylinder, the inner wall of one side, facing the mounting cylinder, of the circulating irradiation channel is transparent, the outer wall of the circulating irradiation channel is in contact with the inner wall of the heating cavity, the upper end of the circulating irradiation channel extends into the mounting cylinder after being bent, a gap is formed between the lower end and the bottom of the tank body, and a plurality of inclined flow deflectors which are circumferentially distributed and inclined towards the same rotating direction are connected between the lower end and the bottom of the tank body. A driving motor is arranged at the upper end of the tank body, and a power output shaft of the driving motor is connected with a stirring shaft; according to the invention, uniform illumination and photo-thermal synergy can be realized, vitamin D3 synthesis can be completed in one step, side reaction is effectively inhibited, and product purity and process economy are improved.

The invention belongs to the technical field of biomolecular markers, and particularly relates to an SNP (Single Nucleotide Polymorphism) molecular marker closely linked with a major QTL (Quantitative Trait Loci) of the provitamin A content of sweet corn kernels and application of the SNP molecular marker. The nucleotide sequence of the SNP molecular marker for regulating and controlling the provitamin A content of the sweet corn kernels is shown as SEQ ID NO: 1; the 269th basic group from the 5'end of the SEQ ID NO: 1 has C / T polymorphism. The SNP marker is used for molecular marker-assisted selection, the character of the provitamin A content of the sweet corn kernels can be predicted only by detecting the SNP basic group of a specific site, the identification method is simple, the selection efficiency is high, the selection target is clear, the method is not influenced by the environment, and a new way is provided for breeding of the sweet corn with the high provitamin A content.

Disclosed herein are plants, namely tomato plants, that have increased carotenoid content and that of beta-carotene and improved nutritional value and improved fruit yield. Also disclosed are methods and materials for producing plants with increased carotenoid content, fruit yield and nutritional value.

1. Name of the designed product: packaging bottle (PILA vitamin B5 glacier water spray). 2. Use of the designed product: used for packaging the corresponding product. 3. Design points of the designed product: in shape. 4. Picture or photo that best indicates the design points: perspective view.

The utility model relates to the field of pig fattening, and discloses a compound vitamin premixing device for piglets, which comprises a mixing barrel, a sealing cover is fixedly arranged at the top of the mixing barrel, a feed port for taking and feeding feed is arranged at the top of the sealing cover, a driving motor is fixedly arranged at the top of the sealing cover, and a feed port is arranged at the top of the driving motor. An output shaft on the driving motor is sleeved with a driving bevel gear, a vertical outer sleeve rod is rotationally installed on the sealing cover, the top of the outer sleeve rod is sleeved with a second driven bevel gear, the outer wall of the outer sleeve rod is sleeved with a rotating disc, and a material mixing rod is arranged on the outer sleeve rod; according to the device, the reverse mixing assembly is designed to be matched with the main outer sleeve rod and the mixing rods on the main outer sleeve rod, so that bidirectional stirring of vitamin raw materials is realized, agglomeration of the raw materials can be more effectively broken through in a bidirectional stirring mode, the vitamin raw materials are more uniformly distributed in the mixing process, and the mixing effect is improved.

The invention provides a vitamin A, vitamin D3 and vitamin E compound microsphere and a preparation method thereof, the compound microsphere is composed of active pharmaceutical ingredients and a carrier material, the active pharmaceutical ingredients are vitamin A (VA), vitamin D3 (VD3) and vitamin E (VE) bulk drugs, the carrier material is polylactic acid-glycolic acid copolymer (PLGA), and the weight ratio (VA: VD3: VE: PLGA) is 1: 1: 1: 7. The prepared vitamin A, D3 and E compound microspheres are uniform in particle size and narrow in particle size distribution. The water solubility, the stability and the bioavailability of insoluble medicines such as vitamin A, vitamin D3 and vitamin E are improved, long-acting slow release is realized, and the clinical curative effect is enhanced.

The present invention relates to a docosahexaenoic acid ester with an alcohol chosen among the group-B vitamins or provitamins, advantageously comprised by: nicotinyl alcohol of the following formula: 1 pantthenol of the following formula:2 and inositol of the following formula:3 or with isosorbide of the following formula:4 or isosorbide mononitrate of the following formula:5 It also relates to a method of preparation of same, a pharmaceutical composition same and the of same in the treatment or prevention of cardiovascular disease, in particular auricular fibrillation.

Disclosed herein is an improved, cost-effective scalable process for preparation of 25-OH 7-DHC ( 25-OH provitamin D3(Calcifediol).

The invention provides an in-situ slow-release gel carrier. The in-situ slow-release gel carrier comprises the following raw materials in parts by weight: 40-70 parts of egg yolk lecithin; 15 to 30 parts of tricaprylin; and 15 to 30 parts of normal propyl alcohol. According to the in-situ sustained-release gel disclosed by the invention, the egg yolk lecithin which has similar compatibility with fat-soluble vitamin D3 and can be used for better dissolving the vitamin D3 is taken as a carrier, and the prepared in-situ sustained-release gel can be used for slowly releasing the vitamin D3 under the combined action of the tricaprylin and the n-propyl alcohol, and meanwhile, the hypocalcemia of the dairy cow is prevented.

Cosmetic composition, in cream form, comprising phytokeratin; cellulose; provitamin B5; biotin; glycerin; at least one oil selected from castor oil, jojoba oil, olive oil, rosehip oil, sweet almond oil, argan oil, avocado oil or prickly pear oil; at least one floral water; and a glycerol and stearic acid ester, and its use in a cosmetic treatment of eyelashes and eyebrows.

1. Name of the designed product: packaging bottle (O'GULIA Agulia Vitamin B5 cream). 2. Use of the designed product: bottle for packaging cosmetics. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photograph best indicating the design points: perspective view.

The present application relates to a method and application of preparing a vitamin D dry powder raw material wrapped by a nano fat emulsion in the technical field of vitamin D raw material preparation, and it comprises the following steps: weighing the preparation material, the preparation material includes the following components and their mass percentages: fat-soluble vitamin D or vitamin D analog 0.5-20%, solubilizing component 1-5%, lecithin packaging material 1.5-10%, auxiliary packaging material 0.1-1%, antioxidant 0.01-0.05% and ion complexing agent 0.01-0.02%, and the remainder is excipient; the solubilizing component, fat-soluble vitamin D or vitamin D analog, lecithin packaging material, auxiliary packaging material, antioxidant and ion complexing agent are mixed to form colostrum; colostrum is homogenized by high pressure to a particle size of less than 500nm to obtain a fat emulsion vitamin D liquid; excipients are added to the fat emulsion vitamin D liquid, stirring and dissolving after filtering through a filter membrane, drying, and then crushing and sieving to obtain a nano fat emulsion wrapped vitamin D dry powder raw material. The present application can improve the stability and bioavailability of vitamin D raw materials.

The invention relates to the field of pharmacy, in particular to a production process of a vitamin K1 injection, which comprises the following steps: S1, weighing 80-120 parts by weight of vitamin K1, 650-750 parts by weight of polysorbate 80 (II), 200-220 parts by weight of propylene glycol, 25-35 parts by weight of sodium pyrosulfite, 1-3 parts by weight of activated carbon, 80-120 parts by weight of sodium acetate, 2-6 parts by weight of 36% acetic acid and 10L of water for injection; s2, concentrated preparation; s3, diluting and encapsulating; and S4, sterilizing, detecting leakage, performing light inspection and packaging. The raw materials and auxiliary materials comprise vitamin K1, polysorbate 80 (II), propylene glycol, sodium pyrosulfite and the like, and polysorbate 80 (II) is used as an emulsifier, so that the composition has the characteristics of good solubilizing effect, high stability, low toxicity and the like, the dissolving effect is remarkably improved, the vitamin K1 raw material medicine is fully dispersed, the pH value of the product is controlled within a proper range, the composition can resist terminal sterilization, and the composition does not contain components such as preservatives and the like, and is suitable for industrial production. Toxic and side effects are avoided, and the product safety is good.

Disclosed herein is an improved and efficient process for synthesis of vitamin D3 and its analogue Calcifediol from Ergosterol. Particularly, the present invention discloses the synthesis of key intermediate 3β-tert-Butyldimethylsilyloxy-22-hydroxy-23,24-bisnorchola-5,7-diene (5), and novel intermediate β-tert-Butyldimethylsilyloxy-22-iodo-23,24-bisnorchola-5,7-diene (9) by a simple and cost effective process. The industrially viable processes for preparation of said intermediate(s) results in providing provitamins with various side chains and the desired products in high yield.

The invention relates to the field of pharmacy, in particular to a composition containing vitamin D3 and provitamin D3 and a preparation method of the composition. The provitamin D3 and the vitamin D3 are simultaneously clathrated by cyclodextrin to form a water-soluble clathrate compound, and the provitamin D3 and the vitamin D3 are stabilized at a certain ratio to maintain the stability of the vitamin D3. The preparation method disclosed by the invention is simple, low in equipment requirement, simple in process and operation, suitable for large-scale production and capable of greatly reducing the production cost.

Composition consisting of 1A) 0.02-1.0 wt% guggulsterone based on the total weight of the composition, 1B) 30-90 wt% lipids based on the total weight of the composition, wherein lipids are selected from the group consisting of oils, fats, fatty acids, waxes, triacylglycerides, phospholipids, fat-like substances and / or isoprenoids, 1C) 2.0-7.0% by weight of vitamins and / or provitamins based on the total weight of the composition, wherein vitamins are selected from the group consisting of vitamin C, vitamin B1, vitamin B3, vitamin B5, vitamin B6, vitamin B2, vitamin B8, vitamin B9, derivatives thereof and / or mixtures thereof, 1D) 2.0-10.0 wt% additives based on the total weight of the composition, wherein additives are selected from the group consisting of release agents, dyes, gloss agents, emulsifiers, emulsion stabilizers, thickeners, plant extracts, stabilizers, fragrances, sugar substitutes, UV filters and / or combinations thereof, 1E) 40-60 wt% water based on the total weight of the composition, 1F) 0 wt% or 0.01 to 2.0 wt% diosgenin based on the total weight of the composition, where 1A) Guggulsterone, 1B) Lipids, 1C) Vitamins, 1D) Additives, 1E) Water and 1F) Diosgenin are different from each other, and wherein the composition contains xylitol as a 1D) additive.

The instant invention relates in general to the field of pain relief, and related methods of use, and more particularly, to topical or oral formulations for pain relief. The formulation comprises spilanthol, pellitorine, pro-vitamin B5, and optionally menthol and beta-caryophyllene. The formulations can be used to treat joint pain. The formulations can also be used to treat Alzheimer's disease and Sjogren's Syndrome.

The invention relates to an edible oil composition containing vitamin D3, 7-dehydrocholesterol and provitamin D3. Typically, according to the invention, it contains equal to or greater than 5 mg per 100 g of the composition; 10 mg; 15 mg; 20 mg; 21 mg; 22 mg; 23 mg; 23.5 mg of the raw materials; 24 mg; 24.5 mg of the raw materials; the mass of 7-dehydrocholesterol is 25 mg.

The invention relates to the technical field of biomedical materials, in particular to a skin wound and mucous membrane repairing composition using an exosome vesicle delivery technology and a preparation method and application thereof.The skin wound and mucous membrane repairing composition is prepared from, by weight, 25-35 parts of glycerinum, 5-9 parts of sodium hyaluronate, 3-7 parts of tetrahydromethylpyrimidine carboxylic acid, 1-3 parts of 1, 3-butanediol, 1-3 parts of 1, 3-butanediol, 1-3 parts of 1, 3-butanediol, 1-3 parts of 1, 3-butanediol, 1-3 parts of 1, 3-butanediol, 1 The exosome is prepared from the following components in parts by weight: 3-7 parts of 1, 2-hexanediol, 3-7 parts of p-hydroxyacetophenone, 3-5 parts of carbomer, 2-4 parts of sophocarpidine, 0.5-1.5 parts of arginine, 25-35 parts of exosome, 8-12 parts of crithmum maritimum callus culture filtrate, 15-25 parts of provitamin B5 and the balance of purified water. The exosome is used as a core repair component, has good compatibility with humanized tissue, can be rapidly absorbed by damaged tissue, and can regulate inflammatory response, promote cell proliferation and differentiation and accelerate wound healing by releasing active molecules; meanwhile, under the synergistic effect of components such as crithmum maritimum callus culture filtrate and provitamin B5, the repairing effect is further improved, and wound surface or mucosa repairing is facilitated.

The invention relates to the technical field of pet food, in particular to nutritional supplement granules for pets and a preparation method of the nutritional supplement granules. Aiming at the problems that in the prior art, the utilization rate of the euphausia superba oil is low and part of pets are allergic, the DHA algal oil and the pumpkin seed oil are added and have a synergistic effect, so that the utilization rate of the euphausia superba oil is increased, and the conditions of diarrhea, skin itch, erythema and ear infection caused by allergy are effectively relieved; meanwhile, the resistance of pets to the euphausia superba oil is reduced through wrapping of the nutritional layer; vitamin raw materials with excessive taste are prepared into taste-masking pellets to be added into the nutrition layer, the conflict psychology of pets eating the vitamin supplement is solved, the palatability can be improved by adjusting the formula of the taste-masking pellets without additionally adding the taste layer, meanwhile, the slow-release function is achieved, and the gastrointestinal pressure of the pets is relieved.

The invention relates to a transgenic breeding method capable of simultaneously improving carotenoid content, stability and bioavailability of rice endosperm. Expression cassettes of NeuroAL1, NeuroAL2, NeuroAL3 and arabidopsis thaliana tHMGR are constructed by using a rice endosperm specific promoter, all the genes are not positioned in a plastid, and after rice is transformed, transgenic rice with red seed endosperm and rich provitamin A carotenoid and fungus specific carotenoid is obtained, or the NeuroAL1 is replaced by UstiAL1, the seed endosperm color is changed into orange yellow, and the transgenic rice with rich provitamin A carotenoid and fungus specific carotenoid is transformed into fungus specific carotenoid and rich provitamin A carotenoid and fungus specific carotenoid. Compared with the traditional golden rice, the golden rice has the advantages that more provitamin A carotenoids are accumulated, and compared with the traditional golden rice, the content of the provitamin A carotenoids in the endosperm of the golden rice is higher, the light stability is higher, and the bioavailability is also higher, so that a new generation of golden rice with richer nutrition is created on the basis of a new strategy of cytoplasm de novo synthesis.

A cosmetic procedure is envisaged for the optimization of aesthetic parameters of the skin and skin appendages carried out over a period of 28 days, wherein the period of 28 days includes a first week corresponding to a menstrual phase, a second week corresponding to a follicular phase, and a third and fourth week corresponding to a luteal phase; wherein the procedure includes, during the first and fourth week, cleansing and treating the skin or skin appendages with respectively a first and a second mixture including at least polyphenolic structures contained in plant extracts, unsaponifiable substances of oils or fats, provitamins, vitamins and / or derivatives of group B; and, during the second and third week, cleansing and treating the skin or skin appendages with respectively a third and a fourth mixture including at least biomimetic structures, natural or natural origin polymers, unsaponifiable substances of oils or fats, provitamins, vitamins and / or derivatives of groups C and E, and wherein the second and fourth mixture further include Ectoine and Sodium Hyaluronate.