The invention relates to the technical field of biomedical materials, in particular to a
skin wound and
mucous membrane repairing composition using an
exosome vesicle delivery technology and a preparation method and application thereof.The
skin wound and
mucous membrane repairing composition is prepared from, by weight, 25-35 parts of glycerinum, 5-9 parts of
sodium hyaluronate, 3-7 parts of tetrahydromethylpyrimidine
carboxylic acid, 1-3 parts of 1, 3-
butanediol, 1-3 parts of 1, 3-
butanediol, 1-3 parts of 1, 3-
butanediol, 1-3 parts of 1, 3-butanediol, 1-3 parts of 1, 3-butanediol, 1 The
exosome is prepared from the following components in parts by weight: 3-7 parts of 1, 2-hexanediol, 3-7 parts of p-hydroxyacetophenone, 3-5 parts of carbomer, 2-4 parts of
sophocarpidine, 0.5-1.5 parts of
arginine, 25-35 parts of
exosome, 8-12 parts of crithmum maritimum
callus culture filtrate, 15-25 parts of
provitamin B5 and the balance of
purified water. The exosome is used as a core repair component, has good compatibility with humanized tissue, can be rapidly absorbed by damaged tissue, and can regulate
inflammatory response, promote
cell proliferation and differentiation and accelerate
wound healing by releasing active molecules; meanwhile, under the synergistic effect of components such as crithmum maritimum
callus culture filtrate and
provitamin B5, the repairing effect is further improved, and
wound surface or mucosa repairing is facilitated.