The invention discloses a non-damage artery blocking clamp for organ transplantation. The non-damage artery blocking clamp comprises a base, a sliding groove, a fixed clamping plate, a sliding block,a mounting frame, a spring, a clamping plate, a button, a mounting sleeve, a connecting handle, a movable clamping plate, extrusion pads, a shell, a through groove, a grip handle, an extension grooveand a rotating wheel. The non-damage artery blocking clamp has the beneficial effects that the movable clamping plate can move in the front-rear direction under driving of the connecting handle, and thus arteries needing to the operated can be clamped and loosened through very easy operation; a tooth groove is formed in the upper end of the clamping plate, teeth are arranged in the shell, whereinthe tooth groove and the teeth can be mutually engaged, thus the clamping plate and the shell can be fixed together very firmly, the clamping effect is guaranteed, and loosening is effectively prevented; the soft extrusion pads are pasted to the faces, mutually attached, of the fixed clamping plate and the movable clamping plate correspondingly, thus stimulation to arterial vascular walls is lowered, and damage to blood vessels is prevented; and the connecting handle penetrates through the extension groove and is overlapped on the rotating wheel capable of freely rotating, thus the connectinghandle moves more smoothly, and borne resistance is small.