The invention provides a valve stent, which comprises a stent main body arranged in a grid shape, at least a grabbing lug connected with the stent main body and a flange connected with the stent mainbody. According to the invention, the outer diameter D of the flange is larger than the diameter d of the connecting position of the flange and the stent main body, so that the lower horizontal planeof the flange is tightly attached to a heart native valve ring and valve leaflets, the edge upwarping end surface is tightly attached to the inner wall of left atrium, the upper limiting and sealing effects are achieved, and the valve stent is prevented from sliding out towards the left ventricle end; when the valve stent is compressed into a sheath, the grabbing lug is embedded into the stent main body grids connected with the grabbing lugs, so that the stent thickness of the valve stent after being pressed, held and reduced is reduced, and the valve stent can intervene into a human body through a femoral vein path so as to reduce the diameter of a conveyor catheter and reduce the conveying difficulty and the damage to blood vessels; and the grabbing lug simultaneously grabs native valveleaflet and hooks chordae tendineae to form lower limiting, so that the valve stent is prevented from being disengaged towards the left atrium end due to external force such as blood flow scouring, heart extrusion and the like.