Pressure control device for arterial perfusion of isolated vascular

Abstract

The invention discloses a pressure control device for the arterial perfusion of an isolated vascular. The device comprises a perfusate circulatory system, a gas system, and a pressure detection and control system. The perfusate circulatory system comprises a sealed pipe; the sealed pipe is connected to a pipeline which forms a circulatory pipeline with the sealed pipe; the end of the pipeline where the perfusate inflows is inserted below the liquid level of the sealed pipe; and a peristaltic pump and the isolated vascular are arranged on the pipeline. The gas system comprises an air inlet pipeand an air outlet pipe which are connected to a cavity part of the sealed pipe, wherein the air inlet pipe is connected to an air pump and a gas flow regulating valve, and the air outlet pipe is connected to an electromagnetic exhaust valve and a gas flow regulating valve. The pressure detection and control system comprises an air pressure sensor inserted into the cavity part of the sealed pipe,a control system connected to the air pressure sensor, and a display screen connected to the control system. According to the pressure control device for the arterial perfusion of the isolated vascular, the isolated vascular can be ensured to obtain sufficient nutrients when in-vitro culture; meanwhile, the dynamic pressure fluctuation of the perfusate can be maintained to be consistent with the change rule of human body pulse wave.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, and in particular relates to an arterial perfusion pressure control device and a pressure control method for isolated blood vessels. Background technique [0002] The development of artificial organs for organ transplantation is of great significance to solve the current shortage of organ transplant sources and improve human health, and it is also a key direction of biomedical development. With the advancement of science and technology and the continuous development of organ regeneration research, foreign countries have reported the in vitro construction of artificial biological hearts, artificial biological livers, artificial biological kidneys, and artificial biological lungs. These artificial organs are in their infancy, and animal transplantation has proved Can survive for a while, but clinical transplantation is not yet supported. How to optimize the culture method and further stu...

AI Technical Summary

Problems solved by technology

In this utility model, the perfusion pressure is not controlled, which will cause the continuous contraction and spasm of the tiny blood vessels, so that the medicinal liquid cannot completely and evenly enter the tissue, so that the perfusion of the deep fascia and skin cannot be achieved, and ultimately directly affect the authenticity of the experimental results

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