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90 results about "Tissue Part" patented technology

Any component of the anatomical structure consisting of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing a specific function.

InDel molecular marker of avena sativa and application of InDel molecular marker

The invention relates to the technical field of crop molecular genetic markers, and discloses an InDel molecular marker of avena nuda and application thereof.The molecular marker is a group of 314bp deletion variation and 2bp insertion variation in the 610439484-610440026 interval of the 5C chromosome position of a reference genome of an avena nuda variety OT3098, the nucleotide sequence of the deletion variation is shown as SEQ ID NO.1, the nucleotide sequence of the insertion variation is shown as SEQ ID NO.2, and the nucleotide sequence of the insertion variation is shown as SEQ ID NO.3. The nucleotide sequence of the insertion variation is 5 '-AA-3'. The molecular marker provided by the invention can realize stable detection in agarose gel electrophoresis by combining a specific primer pair (SEQ ID NO.2-3) with an optimized touchdown PCR (Polymerase Chain Reaction) program, has the advantage of being not influenced by a tissue part and a growth period, and provides an efficient and reliable technical means for oat germplasm identification, seed purity detection and molecular breeding.
Owner:CHENGDU UNIV +3

Robotic sewing system and method of use

A centrally coordinated and synchronized robotic system for robotic sewing procedures, such as bilateral spinal robotic sewing procedures, includes multiple robotic arms and a controller that can manipulate the robotic arms to position tools, end effectors, cameras, or navigation elements, such as a suturing needle and a marker or label for use in a robotic sewing procedure. The markers or labels may be placed on different tissue portions, including for example skin and surgically exposed tissue, to help guide the robotic arms and deployment of the markers to perform bilateral robotic sewing.
Owner:LEM SURGICAL AG

Bone align and joint preparation device and method

A bone displacement system includes an anchoring portion, a tool engaging portion, a compression distraction mechanism, a lateral body and a distal body. The anchoring portion has an aperture for receiving a wire to connect the anchoring portion to a proximal bone. The anchoring portion is connectable to a downwardly depending member for holding a tissue portion. The tool engaging portion is connected to the anchoring portion and is configured to connect a tool thereto. The compression-distraction mechanism is connected to the anchoring portion. The lateral body is connected to the compression-distraction mechanism and engageable with a lateral bone. The distal body is connected to the compression-distraction mechanism. The distal body has an aperture for receiving a wire to connect the distal body to a distal bone. The compression-distraction mechanism is configured to move the anchoring portion relative to the distal body.
Owner:MEDARTIS AG

Devices and methods for tissue shaving

A device for tissue shaving includes an elongated outer cannula having a tissue pinching distal end, an elongated inner shaft extending through the cannula and having a tissue shaver at a distal end. The tissue pinching distal end of the outer cannula is configured to pinch a portion of the tissue and the tissue shaver of the inner shaft is configured to be rotated and cut the pinched tissue portion via a shearing action.
Owner:KIC VENTURES LLC

A bladder tumor specimen extractor

The application discloses a bladder tumor specimen extractor which comprises an adjusting transmission assembly capable of controlling preliminary cutting, a separating assembly capable of separating a tissue part and a liquid part of the bladder tumor and an operating handle. The application belongs to the technical field of bladder tumor surgery. When the bladder tumor temporarily stays on a tissue liquid passing layer, the removed bladder tumor can be punctured by a plurality of groups of puncture heads, so that the tissue part of the bladder tumor is blocked by the tissue liquid passing layer, and the tissue liquid and the plasma part of the bladder tumor can pass through the tissue liquid passing layer and enter a liquid storage bag. After sampling is completed, medical staff can take out the liquid storage bag to sample the tissue liquid and the plasma part of the bladder tumor, and the tissue part of the bladder tumor can be sampled from the tissue liquid passing layer. The application provides a brand-new bladder tumor sampling experience, greatly reduces the possibility of tissue liquid and plasma remaining in the bladder and brings convenience to medical staff.
Owner:SHANGHAI PUDONG HOSPITAL

Novel pelvic and abdominal cavity drainage tube

The novel pelvic and abdominal cavity drainage tube comprises a main pipeline, the main pipeline comprises a suction section and a drainage section which are connected with each other, a through suction channel is formed in the suction section in the length direction, a main channel and a plurality of auxiliary channels are formed in the drainage section in the circumferential direction, and the main channel and the auxiliary channels are through in the length direction of the suction section; the projection area of the main channel is larger than that of the auxiliary channel, and strip-shaped openings are formed in the side walls, corresponding to the drainage section, of the main channel and the auxiliary channel. The auxiliary pipeline is circumferentially provided with a plurality of drainage grooves, the outer wall of the drainage section is provided with a connecting hole corresponding to the main channel, one end of the auxiliary pipeline is inserted into the main channel along the connecting hole to enable the drainage grooves to be communicated with the main channel, drainage of the groove area of the tissue part is achieved through the auxiliary pipeline, and therefore the overall drainage range of the drainage tube is enlarged; a better drainage effect is obtained; the overall size can be reduced through connection of the auxiliary pipeline and the main channel, and therefore the wound size of the human body is reduced.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Cigar tobacco tissue thickness measuring method and cutting device

The invention discloses a cigar tobacco tissue thickness measuring method and a cutting device, and relates to the technical field of tobacco tissue thickness measurement, and the method comprises the following steps: S1, carrying out screening treatment before cigar tobacco and rootstock cutting; s2, device cutting module selection and parameter setting work; s3, tobacco plant rhizome and leaf tissue structure slices are cut; s4, tissue slice electron microscope scanning and image selection work; and S5, carrying out tissue slice image part identification and division and average thickness calculation. The method solves the problems that in the prior art, in thickness measurement of different tissue structures of tobacco leaf sections, most methods or leaf surface image analysis systems are used for estimating and reading scale scales, and due to the fact that thickness distribution of tissue parts of leaves is not uniform and consistent, a traditional scale measurement method is large in error due to different selected measurement point positions, and the measurement accuracy is poor. And the average thickness of each part cannot be quickly and accurately measured.
Owner:ZHENGZHOU UNIVERSITY OF LIGHT INDUSTRY

Soft tissue implant systems, instruments, and related methods

The present disclosure relates to instruments, implant systems, and methods for joining bone and / or tissue portions. The instrument includes a handle portion; an inserter portion comprising an insertion portion and a tip portion; a guide portion comprising a medial end component and a distal end component, the guide portion extending from a distal end portion of the handle portion to a bone engagement end of the inserter portion; a passageway extending through the inserter portion from the distal end of the handle portion to the bone engagement end of the inserter portion; and a hole that extends from an exterior surface of the handle portion and the guide portion to the passageway, wherein the insertion portion and the tip portion of the inserter portion are positioned past the distal end component of the guide portion when the handle portion, the inserter portion, and the guide portion are mated.
Owner:PARAGON 28 INC

Endoscope imaging device and method, electronic equipment and storage medium

The invention discloses an endoscope imaging device and method, electronic equipment and a storage medium, and relates to the technical field of image processing. The device comprises an illumination module which is used for providing an illumination light source and comprises a plurality of narrow-band light sources with different colors, and the plurality of narrow-band light sources comprise main spectral bands forming white light; the imaging module is used for imaging the reflected light after the illumination module irradiates the target part of the patient to obtain an RGB image; the processing module is used for decomposing the RGB image into a white light image and a plurality of non-white-light narrow-band images, performing enhancement processing on the plurality of non-white-light narrow-band images, and fusing the non-white-light narrow-band images with the white light image to obtain a narrow-band enhanced target image; wherein the plurality of non-white light narrow-band images respectively represent information formed by different tissue parts for absorbing narrow-band light with different wavelengths. Therefore, on the basis of a full-narrow-band illumination light source and an image decomposition-enhancement-fusion technology, the impression of white light hue is taken into consideration on the premise that focus details are highlighted through imaging.
Owner:ZHEJIANG UE MEDICAL

Soft tissue implant systems, instruments and related methods

Implant systems and related methods for joining bone and / or tissue portions is disclosed. The implant systems include a first flexible anchor tube comprising a first annular side wall defining a first internal cavity, a first longitudinal end and a second longitudinal end, and a second flexible anchor tube comprising a second annular side wall defining a second internal cavity, a first longitudinal end and a second longitudinal end. The implant systems also comprise at least one suture that passes through the first and second side walls a plurality of times. The at least one suture extends along a pattern that prevents the second anchor tube from translating along the at least one suture and allows the first anchor tube to translate along the at least one suture toward the second anchor tube when first and second end portions of the at least one suture are tensioned.
Owner:PARAGON 28 INC

System and method for magnet detection and operational tuning

An apparatus includes a housing configured to be placed over a tissue portion of a recipient, the tissue portion overlaying an implanted device. The housing includes a cavity configured to hold a magnet therein. The apparatus further includes at least one sensor on or within the housing. The at least one sensor is configured to detect the magnet within the cavity and to generate at least one signal indicative of at least one attribute of the magnet. The apparatus further includes control circuitry within the housing. The control circuitry is configured to receive the at least one signal and, in response to the at least one signal, adjust at least one operational parameter of the apparatus.
Owner:COCHLEAR LIMITED

All-suture anchor

Provided herein are suturing systems, methods of anchoring to a bone, methods for anchoring a soft tissue to a bone, and methods of anchoring a first soft tissue portion to a second soft tissue portion. An exemplary suturing system includes an anchor and a suture inserter device. The anchor includes a plurality of anchor inserts coupled to a portion of the suture between a first end and second end of the anchor. The anchor has an insertion configuration that is substantially linear and a deployed configuration that is at least partially nonlinear. The suture inserter device includes a housing comprising a housing lumen and a housing shaft disposed therein, and an inserter fork coupled to the housing shaft. The housing shaft is axially translatable, and the inserter fork is axially translatable, via the housing shaft, between a distal position and a proximal position.
Owner:RESPONSIVE ARTHROSCOPY LLC

Clip applier

The utility model discloses a clip applier. The clip applier comprises an elastic sheet fixedly arranged on a shell; the trigger is rotatably arranged on the shell so that the trigger can rotate to one of the initial position, the clamp feeding position and the clamping closing position, the clamp feeding position is located between the initial position and the clamping closing position in the rotating direction of the trigger, the elastic piece is located on the side, away from the initial position, of the trigger, and when the trigger rotates to the clamp feeding position from the initial position, the trigger abuts against the elastic piece. The elastic piece is arranged on the shell and located on the side, away from the initial position, of the trigger, and when the trigger rotates to the clamp feeding position from the initial position, the trigger abuts against the elastic piece, so that the trigger is subjected to counter-acting force in the rotating direction of the trigger, a user is reminded of force, and the user stops pressing the trigger at the clamp feeding position in time; the ligature clip can be conveniently and accurately conveyed to a surgical tissue part, so that the success rate and efficiency of the surgery are improved, the clip applier is prevented from continuously conveying the ligature clip, and the ligature clip is prevented from being wasted.
Owner:SUZHOU YINGTUKANG MEDICAL TECH CO LTD

Implantable energized medical device, related methods and kit

PendingUS20260192106A1SurgeryMedical device
An implantable energized medical device configured to be held in position by a tissue portion of a patient, the medical device comprising: a first portion configured to be placed on a first side of the tissue portion, the first portion having a first cross-sectional area in a first plane and comprising a first surface configured to face a first tissue surface of the first side of the tissue portion, a second portion configured to be placed on a second side of the tissue portion, the second side opposing the first side, the second portion having a second cross-sectional area in a second plane and comprising a second surface configured to engage a second tissue surface of the second side of the tissue portion, and a connecting portion configured to be placed through a hole in the tissue portion extending between the first and second sides of the tissue portion, the connecting portion having a third cross-sectional area in a third plane and a third surface configured to engage the first tissue surface of the first side of the tissue portion, wherein the connecting portion is configured to connect the first portion to the second portion, wherein: the first, second, and third planes are parallel to each other, and the third cross-sectional area is smaller than the first and second cross-sectional areas, such that the first portion, second portion and connecting portion are prevented from travelling through the hole in the tissue portion in a direction perpendicular to the first, second and third planes.
Owner:IMPLANTICA PATENT LTD

Endoscope with sensor for image acquisition and tissue examination

To provide an endoscope for medical examination and / or treatment of a human or animal body or tissue sections thereof.SOLUTION: An endoscope (10) that is configured for imaging as well as for tissue analysis is disclosed. For this purpose, the endoscope (10) comprises an image sensor to which multiple optical devices are arranged in order to carry out different tasks with one and the same image sensor, particularly the task of imaging and measurement tasks concurrently or temporally graded.SELECTED DRAWING: Figure 1
Owner:ERBE ELEKTROMEDIZIN GMBH

Subtissue implant material

In certain embodiments, the present disclosure provides methods of treating diseased or damaged tissue in a patient. In some forms the methods comprise introducing a photocurable composition to the diseased or damaged tissue, the photocurable composition comprising a photoactivatable metal ligand complex, a matrix forming polymer, and an electron acceptor. Such methods may further comprise irradiating the photocurable composition through a tissue portion to induce a photocrosslinking reaction forming crosslinks between individual polymers of the matrix forming polymer within the photocurable composition.
Owner:COOK BIOTECH INC

Tissue-PEXY systems and associated devices and methods

PCT designated stageWO2025255214A9Suture equipmentsSuturing needleAnatomy
The present technology is generally directed to tissue-pexy systems including a probe and a suture thrower removably coupleable to the probe. The probe can be partially inserted into a body cavity of a patient. The suture thrower can have a tissue-receiving portion and a needle. The tissue-receiving portion can include a first concave surface defining a first recess for receiving a first tissue portion and a second concave surface defining a second recess for receiving a second tissue portion. The needle can be movable between a retracted state and an extended state. The needle can be configured to pierce through the first and second tissue portions when moving from the retracted state to the extended state. Also, the needle can be configured to pull a suture device through the first and second tissue portions when moving from the extended state to the retracted state.
Owner:ALTYX MEDICAL INC

Endoscope with integrated tissue acquisition capability

PendingUS20260248367A1EndoscopeTarget tissue
A tissue closure system includes an endoscope having first and second lumens therethrough, first and second control elements disposed within the first and second lumens, respectively, and a tissue engaging portion integral with a distal end of the endoscope. The tissue engaging portion includes a tissue acquisition assembly and a tissue closure assembly. The tissue acquisition assembly is controllable via the first control element, and the tissue closure assembly controllable via the second control element. The tissue engaging portion includes a tissue grasping portion for engaging first and second target tissue portions disposed adjacent an opening in target tissue. The tissue closure assembly is configured to pierce the target tissue, and to hold the first and second target tissue portions together to close the opening in the target tissue.
Owner:BOSTON SCIENTIFIC SCIMED INC

Tissue cutting tool

The invention belongs to the technical field of medical instruments, and provides a tissue cutting tool which comprises a cutting tool shell, and a cutting device, a camera device and a clamping device are arranged on the cutting tool shell. A to-be-cut tissue part is fixed through the tissue fixing pipe, the driving mechanism drives the linkage part to achieve movement and rotation of the cutting knife body relative to the to-be-cut tissue part, so that cutting operation of the to-be-cut tissue part is achieved, meanwhile, the camera device is further arranged, a user can conveniently achieve visual operation, and the use experience of the user is improved. The clamping device can facilitate the user to adjust the position of the camera device, so that tissue cutting is completed in a stable, accurate and efficient video environment.
Owner:GUANGZHOU CLEAN MEDICAL PROD MFG CO LTD

All-suture anchor

Provided herein are suturing systems, methods of anchoring to a bone, methods for anchoring a soft tissue to a bone, and methods of anchoring a first soft tissue portion to a second soft tissue portion. An exemplary suturing system includes an anchor and a suture inserter device. The anchor includes a plurality of anchor inserts coupled to a portion of the suture between a first end and second end of the anchor. The anchor has an insertion configuration that is substantially linear and a deployed configuration that is at least partially nonlinear. The suture inserter device includes a housing comprising a housing lumen and a housing shaft disposed therein, and an inserter fork coupled to the housing shaft. The housing shaft is axially translatable, and the inserter fork is axially translatable, via the housing shaft, between a distal position and a proximal position.
Owner:RESPONSIVE ARTHROSCOPY LLC

Repair clamp for treating valve regurgitation

The invention relates to the field of medical instruments, in particular to a repair clamp for treating valve regurgitation, a conveying device and a repair clamp detachably connected with the conveying device.The repair clamp comprises a first clamping arm, a second clamping arm and a locking mechanism, and the first clamping arm and the second clamping arm are connected and can form a clamping area; the locking mechanism comprises a restraining piece capable of being tightened, the restraining piece penetrates through the connecting structure on the repair clamp, and the restraining piece can limit relative movement of the clamping arms in the tightened state. The conveying device is detachably connected with the repair clamp and is configured to be capable of conveying the repair clamp to a target heart valve and assisting the repair clamp to be opened or closed so that a target valve leaflet tissue part can be contained in the clamping area; after being folded and used for clamping the valve leaflets, the repair clamp cannot be exposed out of the involution faces of the valve leaflets, damage caused by collision between adjacent valve leaflets and an instrument when the valve is closed is avoided, the number of the repair clamp is reduced, and the load on valve leaflet movement is relieved.
Owner:SHANGHAI ZHIKANG ARK MEDICAL TECHNOLOGY CO LTD

Fibroid ablation positioning device and methods

A method of treating a patient with a bioelectrical system is provided. The method may include inserting a probe into a first position in an anatomy of the patient, the system being provided with a plurality of electrodes; energizing a first electrode of the plurality of electrodes with a measurement level of power; determining a complex impedance in the patient's anatomy; determining whether the first position is a desired position of the probe for ablating a predetermined portion of tissue of the patient, based on the complex impedance determined; and energizing one of the plurality of electrodes with an ablation level of power, the ablation level of power being greater than the measurement level of power. An apparatus for performing BIA on a patient is also provided.
Owner:GYRUS ACMI INC

Medical systems, devices, and methods for impedance-guided tissue sample collection

A medical device includes an end effector assembly at a distal end of the medical device. The assembly comprises a pair of jaw members, a pair of electrodes including first and second electrodes, and first and second conductive wires attached to the first and second electrodes, respectively. Each jaw member includes a jaw and a tang, the jaw being transitionable between open and closed configurations for respectively receiving and collecting a tissue portion as a sample. The first and second conductive wires extend to a proximal end of the medical device and are removably connectable to a computing device configured to generate and provide electrical signals to, and determine an impedance measurement of the tissue portion based on response signals received from, the pair of electrodes contacting the tissue portion, and generate and provide a user interface indicating whether to collect the tissue portion based on the impedance measurement.
Owner:BOSTON SCIENTIFIC SCIMED INC

Clip applier

The utility model discloses a clip applier. The clip applier comprises an elastic sheet which is rotatably arranged on a shell; the trigger is rotatably arranged on the shell so that the trigger can rotate to one of the initial position, the clamp feeding position and the clamping closing position, and the rotating axis of the elastic piece is parallel to the rotating axis of the trigger. The stop rod is arranged on the trigger, the stop rod is suitable for abutting against the elastic piece to enable the elastic piece to deform in the process that the trigger rotates from the initial position to the clamp feeding position, and when the trigger rotates to the clamp feeding position, the stop rod is separated from the elastic piece to enable the elastic piece to vibrate and produce sound; in the process that the trigger rotates from the clamping position to the initial position, the stop rod is suitable for abutting against the elastic piece to drive the elastic piece to rotate so that the elastic piece can avoid the stop rod. Therefore, an obvious prompt can be given out when the clip applier conveys the clip to the forceps head, so that a user stops pressing the trigger at the clip conveying position in time, the ligature clip can be conveniently and accurately conveyed to an operation tissue part, the success rate and efficiency of an operation are further improved, the clip applier is prevented from continuously conveying the ligature clip, and waste of the ligature clip is avoided.
Owner:SUZHOU YINGTUKANG MEDICAL TECH CO LTD

Combination of augment and replacement piece for filling a bone defect

Graft for a bone defect, in particular a tibial head graft for a knee-joint endoprosthesis. It comprises a sleeve-like inner body (2) for implantation at one end of a long bone (99). An outer face of the inner body (2) is designed as a bone contact face (20) for bearing on the surrounding bone margin (97). According to the invention, an outer shell piece (3) is provided which, as a bone replacement piece, is doubled onto the outside of the inner body (2) for filling a defect at the cortical bone margin (97) and is not dimensioned peripherally, such that, in the circumferential direction, it covers only a part of the outer circumference of the inner body (2). The doubled outer shell piece (3) forms a filler piece for a bone defect (bone window 96) at the bone end. Closure of the bone window (96) is achieved, and unwanted contact between the graft and surrounding soft-tissue parts is avoided. Moreover, the graft is thus also supported in the region of the bone window (96). Parts of the bone margin (97) that are still present can thus remain intact, allowing the greatest possible preservation of naturally present bone substance.
Owner:WALDEMAR LINK GMBH & CO KG

Medical devices for impedance-guided tissue sample collection

A medical device includes an end effector assembly at a distal end of the medical device. The assembly comprises a pair of jaw members, a pair of electrodes including first and second electrodes, and first and second conductive wires attached to the first and second electrodes, respectively. Each jaw member includes a jaw and a tang, the jaw being transitionable between open and closed configurations for respectively receiving and collecting a tissue portion as a sample. The first and second conductive wires extend to a proximal end of the medical device and are removably connectable to a computing device configured to generate and provide electrical signals to, and determine an impedance measurement of the tissue portion based on response signals received from, the pair of electrodes contacting the tissue portion, and generate and provide a user interface indicating whether to collect the tissue portion based on the impedance measurement.
Owner:BOSTON SCIENTIFIC SCIMED INC

Bladder tumor specimen extractor

The invention discloses a bladder tumor specimen extractor which comprises an adjusting transmission assembly capable of controlling preliminary dicing, a separating assembly capable of separating a tissue part and a liquid part of a bladder tumor and an operating handle. The invention belongs to the technical field of bladder tumor surgery. When the bladder tumor temporarily exists on the tissue fluid passing layer, the puncture heads can puncture the taken-down bladder tumor, so that the tissue part of the bladder tumor is blocked through the tissue fluid passing layer, and the tissue fluid and plasma part of the bladder tumor can penetrate through the tissue fluid passing layer and enter the fluid storage bag; medical staff can sample tissue fluid and plasma parts of the bladder tumor by taking down the fluid storage bag, the tissue part of the bladder tumor can be sampled from the tissue fluid passing layer, brand-new bladder tumor sampling experience is provided, the possibility that the tissue fluid and the plasma are left in the bladder is greatly reduced, and convenience is brought to the medical staff.
Owner:SHANGHAI PUDONG HOSPITAL

Nerve block simulation training methods and related equipment

The present invention discloses a nerve block simulation training method and related equipment. The method includes: constructing ultrasonic simulation models of different tissue parts of the human body based on standard three-dimensional anatomical structure information and simulated ultrasonic information of different tissue parts of the human body, and associating the ultrasonic simulation models of different tissue parts with the tissue simulator through coordinate information; tracking the relative position information and relative angle information of the simulated ultrasonic probe and the tissue simulator, and generating corresponding simulated ultrasonic images through the ultrasonic simulation model; tracking the position information and angle information of the simulated nerve block puncture needle in the tissue simulator, taking the intersection of the coordinate range of the puncture needle and the coordinate range of the simulated ultrasonic probe section, obtaining the coplanar coordinate range of the puncture needle and the simulated ultrasonic probe section, and converting the point-to-point into the simulated puncture needle ultrasonic image. It solves the problem that the simulated puncture site is limited, the clinical situation cannot be truly simulated, the efficiency of the transformation of simulation teaching to clinical practice is reduced, and the application value of actual clinical cases is lacking.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

All-suture anchor

Provided herein are suturing systems, methods of anchoring to a bone, methods for anchoring a soft tissue to a bone, and methods of anchoring a first soft tissue portion to a second soft tissue portion. An exemplary suturing system includes an anchor and a suture inserter device. The anchor includes a plurality of anchor inserts coupled to a portion of the suture between a first end and second end of the anchor. The anchor has an insertion configuration that is substantially linear and a deployed configuration that is at least partially nonlinear. The suture inserter device includes a housing comprising a housing lumen and a housing shaft disposed therein, and an inserter fork coupled to the housing shaft. The housing shaft is axially translatable, and the inserter fork is axially translatable, via the housing shaft, between a distal position and a proximal position.
Owner:RESPONSIVE ARTHROSCOPY LLC

Composite material, preparation method thereof and application of composite material in preparation of bone tissue repair material

The invention relates to the field of gene therapy, and discloses a composite material, a preparation method thereof and application of the composite material in preparation of bone tissue repair materials, the composite material comprises a porous scaffold and an active component loaded on the porous scaffold; wherein the porous scaffold comprises a multi-arm polyethylene glycol-polyester block copolymer and an inorganic mineral substance; wherein the active component comprises a nucleic acid drug and a carrier for delivering the nucleic acid drug; wherein in the multi-arm polyethylene glycol-polyester block copolymer, the molar ratio of a monomer structure of a multi-arm polyethylene glycol unit to a monomer structure of a polyester chain segment is 1: (50-10000). The composite material disclosed by the invention can support and fill a tissue part, can slowly release the encapsulated gene nano-carrier, can improve the stability of the gene and the efficiency of entering cells, enables the gene to be continuously expressed in the cells, and plays a long-term effective role in disease treatment and tissue regeneration.
Owner:CHINA PETROLEUM & CHEMICAL CORP +1