External synthetic traditional Chinese medicine composition for treating osteomyelitis, sinus tract and intractable ulcer and preparation method thereof

By using low-temperature ultrasonic extraction and multi-dosage form preparation of traditional Chinese medicine combinations such as honeysuckle, the formulation and preparation problems of external Chinese medicine preparations for the treatment of osteomyelitis, sinus tracts and refractory ulcers have been solved, achieving stronger and more stable therapeutic effects, and making them suitable for wound care during infection and repair periods.

CN122140825APending Publication Date: 2026-06-05张红亮
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Patent Information

Application Number
CN202610397691.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-03-30
Publication Date
2026-06-05

AI Technical Summary

Technical Problem

Existing topical Chinese medicine preparations for treating osteomyelitis, sinus tracts, and refractory ulcers suffer from problems such as limited formulation, single dosage form, outdated preparation process, insufficient permeability, and low safety and standardization, resulting in limited therapeutic effects and risks of irritation and allergies.

Method used

Using a combination of traditional Chinese medicines such as honeysuckle, dandelion, violet, phellodendron bark, sophora flavescens, red peony root, angelica sinensis, and borneol, a topical synthetic traditional Chinese medicine composition suitable for osteomyelitis, sinus tracts, and refractory ulcers was prepared through low-temperature ultrasonic extraction, centrifugal purification, and multi-dosage form preparation processes. The composition includes powder, ointment, and liquid, avoiding the destruction of heat-sensitive components by high temperatures and improving permeability and stability.

Benefits of technology

It achieves an integrated treatment effect of anti-inflammatory, antibacterial, tissue regeneration and repair, with stronger and more stable efficacy, suitable for long-term use, avoiding the use of hormones and antibiotics, and is mild in nature, suitable for wound care during the infection and repair stages.

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Abstract

The invention relates to the technical field of traditional Chinese medicine external preparations, in particular to an external synthetic traditional Chinese medicine composition for treating osteomyelitis, sinus tract and intractable ulcers and a preparation method thereof.The external synthetic traditional Chinese medicine composition is prepared from, by weight, 10-15 parts of honeysuckle, 10-15 parts of dandelion, 10-12 parts of herba violae, 6-10 parts of cortex phellodendri, 6-10 parts of radix sophorae flavescentis, 5-8 parts of radix paeoniae rubra, 5-8 parts of angelica sinensis and 1-4 parts of borneol; the ointment is suitable for an infection period and a repair period, realizes integration of inflammation diminishing, bacteriostasis, granulation promoting and repair, adopts low-temperature ultrasonic extraction, avoids high-temperature damage of thermosensitive components, has a stronger and more stable drug effect, contains red peony root, Chinese angelica, frankincense, myrrh and other components for promoting blood circulation and removing blood stasis, can promote penetration of drugs into deep tissues, has a remarkable effect on sinus tract and osteomyelitis wound surfaces, is externally applied with pure traditional Chinese medicines, and has no toxic or side effect. Hormone and antibiotics are not added, the property is mild, and long-term use is facilitated.
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