71 results about "Cashmere goat" patented technology

The invention provides a grazing-supplementary feeding combined regulation and control method for promoting sustainable and efficient production of fattening Alba cashmere goats. The method specifically comprises the steps that the goat breeding scale is determined; grouping the goats; determining a goat grazing regulation and control mode; and determining a goat supplementary feeding regulation mode. According to the method, the grazing area, the everyday grazing duration and the grazing and returning time points of the fattening Alba cashmere goats are optimized and regulated, so that the energy additionally consumed by the goats due to defending against cold and excessive migration is reduced, and the ecological negative effect caused by excessive trampling and forage grass ingestion of the goats is also reduced; and sustainable grazing utilization of the grassland can be realized.

The invention belongs to the technical field of genetic breeding, and particularly relates to an SNP marker influencing a fine cashmere goat and application thereof.The SNP marker comprises a first marker and / or a second marker, and the first marker and / or the second marker influence the fine cashmere size of the cashmere goat; the first marker is located at the 48854986 position on the No.6 chromosome of the down producing goat genome and mutates from G to A, and the second marker is located at the 76025546 position on the No.14 chromosome of the down producing goat genome and mutates from T to C.

The invention belongs to the technical field of animal gene engineering, and particularly relates to a down producing goat lncRNA, an interference vector and application of the interference vector to regulation and control of down producing goat hair follicle development, the down producing goat lncRNA is lncRNA TCONS-00237214 and is used for regulating and controlling down producing goat hair follicle development; the nucleotide sequence of the lncRNA TCONS-00237214 is as shown in SEQ ID NO. 1 (sequence identifier number 1). According to the invention, the hair papilla cells are selected for subsequent experimental verification, and the cell cycle, cell proliferation and cell migration of the hair papilla cells are detected by constructing an interference lncRNA TCONS-00237214 stable transformation hair papilla cell line. Results of the invention show that melatonin can regulate and control expression of lncRNA TCONS-00237214, participate in cell cycle transformation, promote proliferation and migration of hair papilla cells and inhibit apoptosis of the hair papilla cells, thereby affecting generation and development of hair follicles.

The invention provides a method for detecting genes related to early growth traits of Inner Mongolia down producing goats based on copy number variation (CNV). The method comprises the following steps: acquiring whole genome re-sequencing data of 461 Inner Mongolia down producing goats; the method comprises the following steps: detecting autosomal CNV by using CNV native software, and screening out 26,003 non-redundant CNV which covers 1, 015.4 Mb (38.97%) of an autosomal genome; gWAS analysis is carried out on the basis of CNV, 11 CNVs obviously related to early growth traits (birth weight CSZ, weaning weight DRZ, daily gain ADG before weaning and 12-month-old weight ZWT) are identified, and two CNVs influence ADG and DRZ at the same time; seven key candidate genes (ZN845, SOX15, FGF11, GPS2, DVL2, SPRY4 and STAT2) are analyzed and identified through bioinformatics, and GO and KEGG function enrichment analysis is utilized to find that the genes participate in biological pathways such as cell proliferation, differentiation and protein phosphorylation. The invention provides a theoretical basis for molecular marker-assisted breeding of Inner Mongolia down producing goats, and has important scientific value and application prospect.

The invention belongs to the field of functional feeds, and discloses a preparation method of a coarse cereal feed for sheep, which comprises the following steps: crushing one or two coarse cereals of buckwheat, broom corn millet, millet and sorghum, and mixing the crushed coarse cereals with raw materials such as enzymolysis soybean meal and alfalfa meal; adding a compound bacteria solution containing lactobacillus plantarum, lactobacillus acidophilus and saccharomyces boulardii for anaerobic fermentation; the nano zinc oxide and the yucca extract are further strengthened to improve the oxidation resistance and ammonia reduction capacity of the feed; and finally, granulating and spraying a sodium alginate-chitosan coating. Through coarse cereal combination optimization, soybean meal enzymolysis pretreatment and composite flora fermentation synergistic effect, the feed protein utilization rate, the fiber degradation rate and the animal production performance are remarkably improved. Experiments show that the milk fat content of the saanen milk goats fed with the feed is increased by 15-23%, the daily gain of the Alba cashmere goats is increased by 25-35%, the feed conversion ratio is optimized to 11.2-12.3: 1, and compared with the prior art, the feed has outstanding nutrition balance and application pertinence.

The present invention relates to the field of genetic engineering technology, and specifically discloses the application of an lncRNA inhibitor in the preparation of a fibroblast proliferation promoter. The lncRNA is lncRNA MSTRG.12349.1, and the only active ingredient in the lncRNA inhibitor is the interfering sequence of the lncRNA, and the interfering sequence is lncRNA MSTRG.12349.1-sh1. The interfering sequence lncRNA MSTRG.12349.1-sh1 provided by the present invention effectively improves the proliferation ability of fibroblasts by increasing the proportion of cells in the S phase of the cell cycle, and promotes the occurrence and development of secondary hair follicles in the embryonic period of cashmere goats.

The invention belongs to the technical field of animal breeding, and particularly relates to application of a detection reagent of a molecular marker related to the hair length character of a down producing goat. The molecular marker is located at 155, 344, 701-155, 346 and 600 positions on a No.1 chromosome of a goat genome, and the nucleotide sequence of the molecular marker is as shown in SEQ ID NO. 1. It is found that the wool length of an individual with a normal molecular marker area is larger than that of an individual with a deletion molecular marker area, and therefore the cashmere goat variety with the large wool length can be bred by detecting deletion mutation of the molecular marker on the chromosome 1 of the goat genome.

The invention belongs to the technical field of biotechnology and livestock breeding, and particularly relates to a detection method for YAP1 gene insertion or deletion markers of Shaanbei white cashmere goats and application of the detection method. The method comprises the following steps: by taking whole genome DNA (Deoxyribose Nucleic Acid) of a to-be-detected Shaanbei white cashmere goat as a template, carrying out PCR (Polymerase Chain Reaction) amplification on partial fragments of a 5'upstream regulation region of a YAP1 gene, then carrying out agarose gel electrophoresis, and realizing rapid and accurate detection on insertion or deletion polymorphism on a No.15 chromosome (NC030822.1: rs645491525, g.7590812175908122 and NC030822.1: rs653744801 and g.7589798575898001) of a specific site of the YAP1 gene according to an electrophoresis result. A correlation analysis result shows that the YAP1 gene is remarkably related to the growth traits of the northern Shaanxi white cashmere goat, and can be applied to goat molecular marker-assisted selective breeding, so that the establishment of an excellent goat genetic resource group is accelerated.

The present invention relates to the use of a composition comprising one or more proteins from cashmere goat milk as cosmetic, medicament and / or dietary supplement.

The invention relates to the technical field of veterinary diagnosis, discloses a down producing goat pneumonia early diagnosis system and an application method thereof, and aims to solve the problems of insufficient accuracy, timeliness, convenience and continuity in existing down producing goat pneumonia early diagnosis. The system comprises a physiological parameter acquisition unit, an environmental parameter acquisition unit, a data preprocessing unit, a feature extraction unit, a pneumonia diagnosis model unit, a decision early warning unit and a central processing unit. The method comprises the steps of collecting multi-modal data in real time, performing early diagnosis by a deep learning model after preprocessing and feature extraction, and generating early warning according to a result. According to the technical scheme, the physiological and environmental parameters of the down producing goats are comprehensively and continuously monitored in real time, the accuracy and reliability of early diagnosis are improved through deep learning, automatic early warning is achieved, the diagnosis period is shortened, and the morbidity and economic loss are reduced.

The application belongs to the technical field of animal breeding, and particularly relates to application of a detection reagent of a molecular marker related to a long hair trait of a cashmere goat. The molecular marker is located at 155,344,701-155,346,600 on a goat chromosome 1, and a nucleotide sequence thereof is shown as SEQ ID NO. 1. It is found by the application that the length of wool of an individual with a normal type of the molecular marker region is greater than the length of wool of an individual with a deletion type of the molecular marker region, and thus a cashmere goat breed with long wool can be selected by detecting a deletion mutation of the molecular marker on the goat chromosome 1.

The invention relates to the technical field of livestock breeding intellectualization, and discloses an intelligent breeding system and method for full-barn feeding cashmere goats. The method comprises the following steps: collecting position coordinates and attitude information of down producing goats in a breeding house, and collecting environmental parameters of a plurality of position points; identifying a sheep flock subset with a local aggregation situation according to the position coordinates, and synchronously obtaining environmental parameters associated with the geographic position of the subset; deducing an expected behavior evolution trend of the sheep flock subset under the action of the environmental parameters in combination with the attitude information and the associated environmental parameters; judging whether the distribution of the whole cashmere goats needs to be subjected to global intervention or not according to the trend; when it is judged that intervention is needed, the movement guiding priority of each cashmere goat is calculated; and generating a differentiated path guide strategy for each goat based on the priority and executing the strategy to adjust the distribution state of the down producing goats in the shed. According to the invention, active prediction and personalized accurate guidance of sheep flock behaviors are realized, and the intelligent level of breeding management and animal welfare are improved.

The utility model discloses a feed mixing device for down producing goats. The down producing goat feed mixing device comprises a stirring bin, supports are arranged on the two sides of the stirring bin, a motor is installed on the supports, a first screw rod and a second screw rod are symmetrically arranged on the inner wall of the stirring bin, and a third screw rod is arranged at the lower end of the first screw rod and the lower end of the second screw rod; the first screw rod, the second screw rod and the third screw rod are rotationally connected with the inner wall of the stirring bin respectively and can be driven by a motor, and the directions of left threads and right threads of the first screw rod, the second screw rod and the third screw rod are opposite respectively. According to the down producing goat feed mixing device, the first screw rod, the second screw rod and the third screw rod are arranged to achieve the function of smashing and stirring forage at the same time, herdsmen can use common forage such as straw to feed the forage needed by cattle and sheep in one step, and the time and cost for manufacturing the forage are saved.

The application provides sgRNA which specifically targets the Rosa26 safe site of a cashmere goat and application of using CRISPR / Cas9 to complete site-directed knockout and site-directed integration of an EGFP gene. The application firstly uses a bioinformatics method to predict the complete sequence of the Rosa26 site, then designs two sgRNA aiming at the site, constructs a targeting vector based on the CRISPR / Cas9 system, verifies the guiding efficiency of the sgRNA, simultaneously constructs a homologous integration EGFP gene vector, co-transfects the sgRNA and the homologous integration vector into cashmere goat fetal fibroblasts, and obtains a cell strain of the Rosa26 site site-directed integration of the EGFP gene. The efficiency of the sgRNA of the application in specifically guiding Cas9 to cut the Rosa26 site reaches about 40%, effectively reduces the off-target phenomenon existing in the CRISPR / Cas9 system, and further reduces the mutation of non-target gene sequences caused by non-specific cutting. The Cas9 / gRNA expression vector can realize the specific knockout or knock-in of the Rosa26 site at the cell, embryo or even individual level, so as to study the expression of specific genes and provide technical support for the cultivation of new goat breeds.

The present invention provides an sgRNA specifically targeting a cashmere goat safety site H11 and an application of site-directed knockout and site-directed integration of an EGFP gene mediated by a CRISPR / Cas9 system. The present invention first predicts the complete sequence of the H11 site (SEQIDNO.1) using a bioinformatics method, and then designs two sgRNAs (SEQIDNO.2 and 3) for the H11 site, and the DNA sequence of the sgRNA sequence transcribed is shown in SEQIDNO.4 or 5. A targeting vector based on the CRISPR / Cas9 system is constructed, and then the guiding efficiency of the sgRNA is verified by TA cloning sequencing, and a homologous integration EGFP gene vector is constructed at the same time, and finally the screened sgRNA (Cas9 / gRNA co-expression vector) and the homologous integration vector (H11-EGFP) are simultaneously transfected into cashmere goat fetal fibroblasts to obtain a cell line of the H11 site site-directed integration of the EGFP gene. The sgRNA of the present invention can specifically recognize the H11 site of cashmere goats, guide the Cas9 endonuclease to efficiently cut the site, and the targeting efficiency is above 50%, which can effectively reduce the off-target phenomenon in the CRISPR / Cas9 system, thereby reducing the mutation of non-target gene sequences caused by non-specific cutting. By constructing a Cas9 / gRNA expression vector, the specific modification (knockout or knock-in) of the H11 site can be achieved at the cell, embryo, or even individual level, thereby studying the expression of specific genes and providing technical support for the breeding of new breeds of goats.

According to the isolated culture identification and key marker detection method for the down producing goat hair follicle stem cells, trypsin and EDTA are used for jointly digesting skin tissue, and high-activity cells are efficiently obtained; a culture medium containing various growth factors is adopted for culture, and cell proliferation and stemness maintenance are promoted. And identifying and integrating morphological observation, growth curve determination and clone formation experiment to accurately judge the characteristics of the cells. Immunofluorescent staining and real-time fluorescent quantitative PCR are applied to key marker detection, and expression of markers such as CK15, CD34 and beta1 integrin is detected with high sensitivity. The method is high in separation efficiency, accurate in identification and sensitive in marker detection, can provide sufficient high-quality cells for the research on the hair follicle stem cells of the cashmere goat, assists in deeply understanding the biological characteristics and the regulation mechanism of the cells, and is of great significance for improving the yield and quality of cashmere and promoting the development of related biotechnologies.

The utility model provides a portable down producing goat oestrus detector. Comprising an inserting rod, a machine core shell is installed behind the inserting rod, a grip is installed behind the machine core shell, a liquid storage cavity is installed on the machine core shell, and a liquid conveying pipe is connected to the liquid storage cavity. By arranging the liquid storage cavity, the liquid conveying pipe, the liquid conveying plate, the connecting pipe, the mounting plate, the micro water pump, the liquid flow channel and the liquid outlet hole, the automatic lubricating function of the front end of the inserting rod can be achieved, the liquid outlet hole enables lubricating liquid to evenly cover the front end of the inserting rod, then a lubricating film with a certain thickness is formed at the front end of the inserting rod, friction force is effectively reduced, and the service life of the inserting rod is prolonged. The device is simple in structure and convenient to use, pain caused by friction is weakened, non-uniformity of traditional manual smearing is avoided, mucous membrane injury risks caused by friction are remarkably reduced, the situation that the down producing goats are subjected to stress collision is reduced, and the device is small in size, high in integration degree and excellent in portability at the same time.

The present application relates to the field of cosmetic technology, and discloses a preparation process of cashmere goat bone-derived elastin and application thereof in cosmetics. The process comprises: defatting cashmere goat bone particles; using composite rumen microbial flora to perform bionic fermentation to destruct bone matrix and expose active sites; adopting neutral protease and specific elastase to perform stepwise directional enzymolysis; performing hydrophilic modification through transglutaminase catalysis of covalent anchoring of polyglutamic acid and elastin polypeptide; and finally, performing multi-stage membrane interception purification and drying. The present application realizes complete retention of the natural cross-linking structure of elastin under mild conditions, significantly improves water solubility, biological activity and transdermal permeability of the elastin, solves the problems of structural damage and pollution caused by traditional chemical methods, and provides a green path for high-value utilization of cashmere goat by-products.

The invention discloses a simple device for increasing the cashmere yield of cashmere goats.The simple device for increasing the cashmere yield of the cashmere goats.The simple device for increasing the cashmere yield of the cashmere goats.The simple device for increasing the cashmere yield of the cashmere goats.The simple device comprises a breeding shed, a feeding frame is fixedly connected to the surface of the breeding shed, a sliding groove is formed in the surface of the feeding frame, and a sliding plate is slidably connected to the inner wall of the sliding groove; when the motor is started, an output shaft of the motor rotates to drive a first belt wheel to rotate, then a belt is driven to drive a second belt wheel to rotate, then a rotating shaft is driven to rotate on the inner wall of the sliding groove, the belt moves to drive a fixing block to move, and then the sliding plate is driven to slide on the inner wall of the sliding groove. And when feed is put into the breeding shed from the outside of the breeding shed and is transmitted into the breeding shed, the safety of a breeder is guaranteed, and the breeder can feed a flock of sheep more easily.

This invention relates to the field of intelligent livestock farming technology, and discloses a fully automated intelligent feeding method for cashmere goat farming. The method includes: monitoring environmental parameters of the cashmere goat activity area and obtaining corresponding physiological parameters to construct an environmental-physiological dynamic correlation model; determining, based on the model, a data acquisition command to trigger feeding decisions when environmental parameters change; periodically acquiring multi-dimensional observation data containing spatiotemporal information of different subgroups within the area according to the command; extracting behavioral segments representing individual behavior from the data, analyzing their attributes, and classifying them into different feeding decision stages; allocating dynamic feed ratios to subgroups corresponding to each behavioral segment based on the feeding decision stage and a preset feed ratio library; and integrating the ratios of each subgroup to generate a global feeding plan. This invention achieves fully automated intelligent feeding from environment-driven to precise behavior recognition.

The utility model provides an anti-freezing device for breeding down producing goats in a high altitude area. Comprising a water tank; the device is characterized in that one end of the water tank is fixedly connected with a water supplementing tank, the other end of the water tank is fixedly connected with a control box, the top of the water supplementing tank is provided with a locking set, the lower end of the locking set is fixedly connected with a connecting line, the lower end of the connecting line is fixedly connected with a floating ball, and the lower end of the floating ball is fixedly connected with a connecting rod. A conical plug is fixedly connected to the lower end of the connecting rod, an external water pipe is arranged at the bottom end of the water supplementing tank, heating boxes are arranged on the two sides of the water tank, and a temperature controller is arranged at the bottom in the water tank. The goat water heater has the advantages that when the water temperature reaches the set temperature suitable for drinking of goats, the temperature controller cuts off the circuit to stop heating of the heating pipe, the working principle similar to that of a water dispenser can not only achieve the purpose of preventing water from freezing, but also prevent the water temperature from being too high, and meanwhile more electric energy is saved.

The application discloses a kind of northern Shaanxi white cashmere goat muscle satellite cell separation and purification method, the present application uses northern Shaanxi white cashmere goat fetus dorsal longest muscle tissue as test material, by aseptic pretreatment, tissue block inversion adherent culture, primary subculture culture Combination of compound technology of hierarchical differential adherent purification, stably obtain the 5th generation muscle satellite cell.The present application optimizes and adapts culture system and purification process, overcomes the defects of low cell yield, serious interference of mixed cells, activity and poor purity of traditional preparation method.At the same time, the present application also adopts RT-PCR molecular identification and immunofluorescence staining combined with multi-level verification method, from gene and protein level Bidirectional verification cell specificity and differentiation potential, accurately determine the biological properties of cell.The present application process is simple, good stability and repeatability, can efficiently prepare northern Shaanxi white cashmere goat muscle satellite cell, provides important technical support for cashmere goat germplasm resource conservation, muscle development mechanism and muscle regeneration related research.

The invention belongs to the technical field of animal nutrition and feed, and particularly relates to a feed composition, a method for improving fattening performance and meat quality of down producing goats and application, corn straw is used for replacing 40-60% of high-quality forage grass in basic daily ration of the down producing goats, and artemisia ordosica crude polysaccharide accounting for 0.08-0.12% of the total dry matter weight of the daily ration is added; experimental results show that the feed composition can significantly improve the average daily gain (up to 45.25%) of the down producing goats, reduce the feed conversion ratio (up to 27.32%), and improve the apparent digestibility of nutrient substances, the rumen fermentation function and nitrogen metabolism; meanwhile, the slaughter performance can be improved, the meat quality can be improved, physiological and biochemical indexes of blood can be adjusted, and immunity and metabolic health can be enhanced; efficient utilization of corn straw resources is achieved, the problem of shortage of high-quality roughage is solved, and remarkable economic and ecological benefits are achieved.

This invention belongs to the field of animal genetic engineering technology, specifically relating to a cashmere goat circRNA, an interference vector, and their application in regulating cashmere goat hair follicle development. The cashmere goat circRNA is circ-0000987; the base sequence of circ-0000987 is shown in SEQ ID NO.1, and it is used to regulate cashmere goat hair follicle development. This invention reveals for the first time the inhibitory effect of circ-0000987 on the proliferation of cashmere goat papillary cells. The results of this invention show that circ-0000987 plays a proliferative inhibitory role in cashmere goat papillary cells, inhibiting their activity by negatively regulating cell proliferation-related pathways; and participating in the transition of hair follicles from the anagen to catagen phase by inhibiting cell proliferation and promoting apoptosis.

The invention relates to the technical field of feed for down producing goats, in particular to a feed raw material for conditioning meat quality of down producing goats. The feed is prepared from the following raw materials in parts by weight: 85-98 parts of green feed, 15-20 parts of corn straw, 10-15 parts of modified attapulgite, 10-15 parts of mixed fermentation bacterial liquid, 5-8 parts of organic acid, 3-5 parts of liquorice, 5-21 parts of a vitamin additive, 8-15 parts of an amino acid additive, 2-8 parts of biotin and 3-9 parts of modified lignin. The prepared feed significantly improves the breeding benefits of the down producing goats through scientific application of feed additives. The growth of the down producing goats can be effectively promoted and the feeding cost can be reduced through a nutrition synergistic effect. In the aspect of meat quality improvement, the meat color and tenderness are remarkably improved; and the dripping loss of the meat is reduced by enhancing the oxidation resistance.

The invention discloses an insemination device for artificial insemination of down producing goats, relates to the technical field of goat breeding, and aims to solve the problems that the goats are easily frightened and struggled, the insemination efficiency is reduced and disordered excretion is caused when the goats are manually fixed, the goats are difficultly, naturally, comfortably and automatically fixed by the conventional insemination device, and the excretion is remained outside the device to cause pollution. The artificial insemination platform comprises a platform assembly, a protection assembly connected with the platform assembly, two sliding doors, a protective fence and a slope. When the device is used, the body and the two rear legs of a goat can be lifted in an integral supporting mode, and the situation that the goat struggles excessively in the insemination process and hurts people is avoided; meanwhile, the insemination success rate can be guaranteed by limiting the rear legs of the goats, in addition, when the goats are ready for insemination and are ready for driving after insemination, the platform assembly can be cleaned, excrement residues are reduced to the maximum extent, and therefore the service life of the device is guaranteed.

The invention provides a Chinese herbal medicine composition for preventing and treating coccidiosis of northern Shaanxi white cashmere goats and a preparation method and application thereof, and belongs to the technical field of Chinese herbal medicines. The Chinese herbal medicine composition comprises the following components in parts by weight: 10-20 parts of sweet wormwood, 8-16 parts of cape jasmine, 4-8 parts of rheum officinale, 8-16 parts of rhizoma atractylodis, 6-12 parts of radix bupleuri, 10-20 parts of oriental wormwood, 4-8 parts of astragalus membranaceus, 4-8 parts of liquorice, 5-12 parts of sophora alopecuroide and 4-9 parts of antifebrile dichroa. Natural Chinese herbal medicines such as artemisia apiacea and astragalus membranaceus produced in the northern Shaanxi region are developed and utilized, so that the problem of high incidence rate of coccidiosis of the northern Shaanxi white cashmere goats is solved, and the characteristics of medicinal value and no medicine residue of the artemisia apiacea and the astragalus membranaceus are utilized; when the feed additive is used for feeding the Shaanbei white cashmere goats, the problem of chemical medicine residues in animal products can be solved, the immunity of the goats is improved, and the coccidiosis morbidity of the goats is reduced.

The present application belongs to the technical field of livestock breeding, and particularly relates to a breeding ecological shed for cashmere goats, comprising a shed, a footboard, a manure leakage tank and a dredging device, the dredging device comprising a main plate, a driving structure and a plurality of dredging assemblies, the dredging assembly comprising a guide head, in the present application, when the guide head is located directly above the manure leakage tank, the guide head will be in contact with the goat manure blocked in the manure leakage tank in the process of moving downward, at the same time, the goat manure blocked in the manure leakage tank will exert a reverse force on the guide head, as the anti-deviation sleeve continues to slide downward, the impact spring will be gradually compressed, at this time, the elastic potential energy of the impact spring gradually increases, when the elastic potential energy accumulated by the impact spring reaches a certain degree, the elastic force generated by the impact spring is sufficient to overcome the resistance formed by the goat manure blockage, at this time, the impact spring starts to stretch and pushes the cross limiting sliding block downward, so that the guide head extends through the goat manure to the lower side of the manure leakage tank.

According to the optimal algorithm framework method for genome selective breeding of the villus sheep, standardized phenotype data are collected in a unified environment, genotyping with the SNP density not lower than 500,000 is adopted, strict quality control standards and Beagle high-precision interpolation are combined, and the genotype data integrity and accuracy are remarkably improved. According to the method, a structured database containing individual IDs, pedigree, phenotypes, genotypes and quality control logs is constructed, version management and programmed calling are supported, and systematic management and long-term accumulation of breeding data are achieved. According to the framework, the genome prediction accuracy is improved, early seed selection and recessive excellent character improvement are realized, the generation interval is shortened, the genetic progress is accelerated, and the framework has good generalizability and industrial application prospects and is suitable for efficient genetic improvement of main villus sheep varieties such as villus goats and fine-wool sheep.

The cashmere goat fleece fixing device comprises a hurdle, one end of the hurdle is a closed mechanism, and the other end of the hurdle is an open mechanism. Two vertical plates are symmetrically and fixedly arranged at the part, close to the closed end, of the barrier frame; two movable seats are symmetrically and adjustably arranged at the part, close to the opening end, of the barrier frame, and two groups of adjusting mechanisms used for adjusting the positions of the two movable seats are arranged on the barrier frame; fixed clamping jaws with semicircular sections are fixedly arranged on the opposite sides of the two vertical plates and the two movable seats correspondingly, and movable clamping jaws with semi-arc sections are hinged to the portions, close to the fixed ends of the fixed clamping jaws, of the fixed clamping jaws; the free end of each fixed clamping jaw and the free end of the corresponding movable clamping jaw are jointly provided with a locking mechanism. The down producing goat fixing device can effectively fix down producing goats conveniently and quickly when the down producing goats are fleeced, and can meet the fixing requirements of the down producing goats with different body types.