30 results about "Local irradiation" patented technology

1. The name of this design product: red light therapy device. 2. Application of this product design: for whole body or local irradiation beauty treatment. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key points of the design: Design 1 Stereoscopic Drawing 1. 5. Designate Design 1 as the base design.

The method and device for mapping the local irradiation flux of laser target shooting based on phase plate positioning belong to the field of laser target shooting experiments. The present invention aims to solve the problem that the flux data in the existing optical element damage test analysis only uses the average flux as the result, and cannot achieve the correspondence between the target surface beam flux and the damage point. The present invention includes a calibration step for obtaining an affine transformation matrix and a step for performing a laser target shooting experiment to obtain the local irradiation flux of the target material. A phase plate is inserted between the lens and the target material in the target shooting experiment optical path, an array of damage points is formed on the rear surface of the target material, and an affine transformation matrix is ​​constructed. The phase plate is removed and the laser target shooting experiment is performed using the original experimental optical path; the near-field image of the target shooting laser beam is mapped to the target material damage image according to the affine transformation matrix, and the near-field image of the target shooting laser beam and the target material damage image are superimposed to obtain the position of the phase mark point corresponding to the target material damage point; and then the local irradiation flux of the laser target shooting at the location of each damage point on the target material is obtained.

The invention discloses a method and device for regulating and controlling the nonvolatile and reversible refractive index of a silicon nitride optical waveguide, and the method comprises the steps: carrying out the local irradiation of a to-be-regulated and controlled silicon nitride optical waveguide in a silicon nitride photon chip through an optical system, and forming a quasi-circular light spot or a quasi-rectangular light spot; moving the quasi-circular light spot or the quasi-rectangular light spot along the silicon nitride optical waveguide to be regulated and controlled; and the length and the amplitude of the refractive index change of the silicon nitride optical waveguide are regulated and controlled by utilizing the moving distance of the light spot and the irradiation dose. The refractive index of the silicon nitride optical waveguide is regulated and controlled through an optical means, additional blanking, metal connection and shielding design are not needed, additional loss caused by phase change materials, metal and the like is avoided, the cost is reduced to a certain extent, and the method has high adaptability and economical efficiency.

The invention discloses an ultrahigh space-time resolution detection imaging method and system, and relates to the technical field of optics, and the method comprises the following steps: carrying out the photon space-time dynamic modulation of multi-wavelength short-short pulse laser, and enabling the number of photons in a single-pulse local irradiation field to be in a single-photon / few-photon state; the patterned photons subjected to photon space-time dynamic modulation are distributed and miniaturized to a sample containing fluorescent molecules for double / multi-photon excitation under few-photon irradiation, and double / multi-photon fluorescence is collected; through a high temporal-spatial resolution detection means, spectral information, life information and spatial position information of dual / multiphoton fluorescence are obtained, fluorescence information in a field of view is reconstructed, and super-resolution imaging and positioning of the whole field of view are completed. According to the invention, large-view-field, high-frame-frequency and super-resolution fluorescence detection imaging can be realized, and opportunities are provided for solving the major scientific problem of optical diffraction limit and realizing super-resolution fluorescence microscopy technology innovation.

The invention relates to the field of biology and medicine, and discloses application of dapam nitrile in prevention and / or treatment of radioactive intestinal injury. The inventor of the invention finds that dapam nitrile can protect radioactive intestinal injury induced by ionizing radiation local irradiation, including improvement of tissue pathological injury, promotion of intestinal crypt cell regeneration, inhibition of intestinal cell apoptosis, improvement of intestinal cell pyroptosis and reduction of serum inflammatory factor level; therefore, the compound can be used as a potential medicine for preventing and / or treating radioactive intestinal injury.

A disc-type mouse local irradiation device relates to the field of mouse targeted irradiation experiment devices, is provided with a base, and is characterized in that a circular baffle plate is fixedly mounted on the base through a support frame, at least three irradiation notches which are through up and down are arranged on the circular baffle plate in a circular array, a support sleeve is arranged on the base on the periphery of the circular baffle plate, and the support sleeve is sleeved on the circular baffle plate. A circular upper cover plate is arranged on the supporting sleeve above the circular shielding plate, an adjusting sliding groove is formed in the position, opposite to the irradiation notch, of the upper side of the upper cover plate, a window adjusting plate is arranged in the adjusting sliding groove, a positioning bolt is arranged on the window adjusting plate, and an anesthetic gas inlet and an anesthetic gas outlet are formed in the supporting sleeve. The device has the advantages of simplicity and convenience in operation, the same distance between a plurality of mice and a radiation source, small irradiation dose error, good mouse anesthesia effect and the like.

The invention discloses a water-soluble stimuli-responsive o-quinone pyridinium salt prodrug as well as a preparation method and application thereof, and belongs to the technical field of medical chemistry. The prodrug disclosed by the invention can be subjected to structural fracture under the action of stimulating factors, active quinone drugs are selectively released, and non-targeted toxicity is reduced; in combination with a local irradiation mechanism of radiotherapy, the synergistic enhancement effect of the drug effect and radiation is realized, and the tumor killing efficiency is improved; the pyridinium structure improves the hydrophilicity and cellular uptake efficiency of the molecule, and can further access a tumor targeting group.

The invention relates to the technical field of radioactive injury effect research, in particular to a radioactive eye injury model establishment method which comprises the following specific steps: S1, setting a plurality of experimental groups; the experimental group at least comprises a model group receiving different doses of ionizing radiation irradiation and a control group not receiving effective dose of radiation irradiation; s2, selecting an experimental animal, shaving and cleaning the target eye area of the animal needing to be irradiated, and anesthetizing the animal; s3, generating ionizing radiation of a preset type and energy by using a radioactive source, and performing local irradiation on the animal eye target area according to the preset total irradiation dose of each model group; s4, after irradiation is completed, the animals are nursed; the reaction of the animal after irradiation is observed, and scoring is carried out. The effectiveness of the established radioactive eye injury model can simulate typical expressions of eye injury under radiation irradiation of different doses, and a reliable animal model is provided for follow-up research of the generation mechanism of radioactive eye injury and evaluation of prevention and treatment measures.

The invention provides a construction device and a construction method of a radioactive intestinal injury animal model, which are characterized in that a backscattering layer is placed below a mouse body, a dose construction layer covers the mouse body, and the radioactive intestinal injury animal model is established by irradiation of a linear accelerator. The method mainly solves the problem that the high-energy X-ray dose build-up area effect affects non-uniform local irradiation dose distribution of the abdominal cavity of the mouse, a standard irradiation scheme is established by comprehensively considering the high-energy X-ray dose build-up area effect and the backscattering effect, the dose distribution of the abdominal cavity of the mouse irradiated by the scheme is more uniform, and the irradiation efficiency is improved. The induced intestinal injury shows recoverable acute injury and chronic intestinal injury characteristics, and can be used for screening and testing medicines for relieving the intestinal injury caused by radiotherapy.

The invention belongs to the technical field of short-range radar signal processing, and provides a pulse Doppler short-range radar signal processing simulation method based on a multi-scattering-point model. The working process of a pulse Doppler system short-range radar is simulated on the basis of the short-range body target local irradiation radar detection condition, and a body target scattering source model capable of generating echoes is approximately constructed by using a multi-scattering-point structure; partial rigid body target reflection point echoes irradiated by the transmitted signal are calculated, and echo signals in the same range gate range are superposed to form a total echo signal of a body target; carrying out demodulation filtering processing on the echo signal containing noise, and then carrying out target detection by using frequency domain constant false alarm detection and time domain threshold detection so as to obtain target starting point information; according to the technical scheme provided by the invention, the influence of target surface details on the effective echo signal amplitude can be ensured, and meanwhile, the calculation efficiency of short-range radar signal simulation and target starting point information is considered.

The invention relates to a method for producing a motor vehicle body part (2), characterized in that it comprises the following steps: depositing at least one opaque coating on at least a portion of a face (6) of a body (3) of said body part (2), said body (3) being made of a transparent or translucent plastic material; and-removing the opaque coating by means of a laser beam locally irradiating the opaque coating in order to achieve a set of microperforations (8, 10) of the opaque coating, the irradiation path (12, 16, 22) of the laser beam being formed exclusively by a continuous substantially linear trajectory (12 ', 16', 22 ').

The application discloses a kind of ultra-high space-time resolution detection imaging method and system, it is related to optical technology field, including the following steps: to multi-wavelength short pulse laser photon space-time dynamic modulation, make single pulse local irradiation field photon number in single photon / few photon state;The patterned photon distribution microshrink after photon space-time dynamic modulation is carried out on the sample containing fluorescent molecule under few photon irradiation two / multi-photon excitation, collects two / multi-photon fluorescence;Through high space-time resolution detection means, obtain the spectral information, life information and spatial position information of two / multi-photon fluorescence, reconstruct the fluorescence information in field of view, complete the entire field of view ultra-resolution imaging and positioning.The application can realize large field of view, high frame frequency, ultra-resolution fluorescence detection imaging, for solving the major scientific problem of "optical diffraction limit", realize ultra-resolution fluorescence microscopy technology innovation provides opportunity.

The present invention relates to the fields of biology and medicine, and discloses the use of Dapansutrile (OLT1177) in the prevention and / or treatment of acute radiation-induced lung injury. The inventors of the present invention have found that Dapansutrile can prevent and / or treat acute radiation-induced lung injury in mice induced by local irradiation with ionizing radiation, including reducing the lung coefficient, alleviating pulmonary edema, inhibiting the aggregation of pulmonary macrophages, and reducing the secretion of serum inflammatory factors. Therefore, it can be used as a potential drug for the prevention and / or treatment of acute radiation-induced lung injury.

The present invention relates to a method for the controlled selective irradiation of a target area on the surface of a given product or living organism, to enable the localized irradiation of this target area in order to obtain a target effect. This method is implemented by a system comprising an emitting device, at least one measurement and analysis device, and a control device. This method comprises the steps of: - real-time measurement and recording of the actual principal energy at the level of the target area; - analysis and recording of the actual effect obtained at the level of this target area; and - real-time control of the emitting device by the control device, taking into account the measurement of the actual principal energy and the analysis of the actual effect, which are compared respectively to a predetermined energy threshold associated with the target area and to the expected target effect, so that,If the predetermined energy threshold is not reached but the target effect is achieved, irradiation of the target area is stopped. Figure for the abbreviation: 1,

The present invention provides a blood vessel detection method and device, comprising the following steps: irradiating light around and / or locally in a target area to form an irradiation area; obtaining a pickup image of the pickup area, with a specified spacing distance set between the pickup area and the irradiation area; synchronously moving the irradiation area and the pickup area, scanning the target area using the pickup area, and obtaining a development image of the target area. The technical solution of the present invention is adopted, by projecting light sources and capturing images on two adjacent and non-overlapping areas respectively, avoiding the method of directly capturing the light reflection on the skin surface, reducing the noise signal reflected by the epidermis, and improving the signal-to-noise ratio, so as to obtain a dark area after backscattering, and then the position and direction of deep blood vessels with high contrast can be observed.

The invention relates to the field of biology and medicine, and discloses application of suramin sodium in prevention and / or treatment of radioactive intestinal injury. The inventor of the invention discovers that suramin sodium is used for treating radioactive intestinal injury induced by ionizing radiation local irradiation, including improvement of intestinal tissue injury, promotion of intestinal crypt cell regeneration, inhibition of intestinal cell apoptosis and reduction of serum inflammatory factor level, so suramin sodium can be used as a potential medicine for treating radioactive intestinal injury.

The invention belongs to the technical field of UV curing, and particularly relates to a UV curing lamp structure which comprises a lamp holder, a lamp panel, a light-transmitting plate and a reflective mirror. A mounting cavity is formed in the bottom of the lamp holder, and the multiple sets of lamp panels are arranged in the mounting cavity and connected with a power source independently or in parallel. The light-transmitting plate is arranged at the bottom of the mounting cavity and seals the mounting cavity, and a lamplight cavity is formed between the light-transmitting plate and the lamp panel; the reflective mirror is arranged at one end of the lamplight cavity and connected with an adjusting mechanism, and the adjusting mechanism is used for adjusting the included angle between the reflective mirror and the lamp panel. Therefore, the UV curing lamp can realize local irradiation of a product, and can be adjusted through the reflective mirror according to different light intensities of the UV lamp, so that UV curing irradiation of different positions and different requirements of the product is met.

The utility model relates to curtain wall detection technical field, concretely is a curtain wall environment simulation test box. The test box is through the arc guider that sets up in the box body and the sliding seat and adjusts xenon lamp irradiation angle, the fixed frame surface and the lateral portion are equipped with the lifting plate that can vertically lift and the translation plate that can horizontally move, the both staggered arrangement controls the xenon lamp light illumination coverage range through independent drive, realizes local irradiation simulation. The box body side wall is equipped with the water inlet pipe with ordinary shower nozzle and atomizing shower nozzle, and the top ventilation pipe is configured with a fan and a heating pipe, which cooperates to simulate wind, rain, temperature and humidity environment. The drain pipe is used for draining water. The scheme solves the problem of local light simulation missing, improves the environmental factor coordination, and enhances the test authenticity.

The application provides a method for constructing a nasopharyngeal carcinoma tumor-bearing rat model with increased nasal cavity secretion, and the rat model is constructed by subcutaneous injection of murine nasopharyngeal carcinoma cells (FAT) and local irradiation by X-ray irradiation. The rat model constructed by the method has both the tumor-bearing state of nasopharyngeal carcinoma and the side effect state of increased nasal cavity secretion after radiotherapy, and the immune system still exists, and is suitable for the research on the effect and mechanism of drugs, especially traditional Chinese medicines, for exerting a therapeutic effect by immunity.

The present application relates to the field of biology and medicine, and discloses application of tranilast in prevention and / or treatment of radiation-induced intestinal injury. The inventors of the present application find that tranilast protects against radiation-induced intestinal injury induced by local irradiation of ionizing radiation, including improving the survival rate of mice, improving histopathological injury, promoting regeneration of intestinal crypt cells, and reducing the level of serum inflammatory factors, and thus can be used as a potential drug for preventing and / or treating radiation-induced intestinal injury.

The invention discloses cobalt-60 irradiation efficient sterilization equipment, and belongs to the field of irradiation sterilization, the cobalt-60 irradiation efficient sterilization equipment comprises a box body and a box door arranged on one side of the box body, cobalt-60 irradiation devices are fixedly installed on the inner top wall and the inner side wall of the box body, a motor is fixedly connected to the bottom of the box body through a supporting frame, a reciprocating screw rod is fixedly installed at the output end of the motor, and a motor is fixedly installed on the reciprocating screw rod. A fixing cylinder is fixedly installed on the inner bottom wall of the box body, a lifting rod is slidably arranged in the fixing cylinder through a sliding assembly, and the end, away from the motor, of the reciprocating lead screw penetrates into the lifting rod. The cobalt-60 irradiation devices are arranged on the top wall and the side wall in the box body, cobalt-60 gamma rays irradiate to-be-irradiated objects on the placing plate, all parts of the objects on the placing plate can uniformly receive ray irradiation in cooperation with lifting and rotating movement of the placing plate, the problem that the local irradiation dose is insufficient or too high is effectively solved, and the irradiation efficiency is improved. The sterilization efficiency and the sterilization effect are greatly improved.

The invention relates to a method for manufacturing a motor vehicle body part (2), characterized in that it comprises the following steps: - deposition of at least one opaque coating on at least a portion of a face (6) of a main body (3) of the body part (2), the main body (3) being made of transparent or translucent plastic, and - creation of a series of micro-perforations (8, 10) in the opaque coating by removing the opaque coating using a laser beam locally irradiating the opaque coating, an irradiation path (12, 16, 22) of the laser beam consisting solely of successive substantially straight path lines (12', 16', 22'). Figure 2

The method for manufacturing a vehicle component (2) comprises a step of applying a paint layer (6) on a transparent or translucent component (4), and a step of locally irradiating the paint layer (6) with laser radiation (10) in order to etch the paint layer (6) in part of its thickness according to a predetermined pattern.

The invention provides a technology for manufacturing a window glass with a resin member for a vehicle. The technology enables the temporary fixation of the member to be more easily carried out in a manufacturing method of a window glass with a resin member. A method for manufacturing a vehicle window glass with a resin member includes an arrangement step for arranging a resin member on a vehicle window glass via an adhesive, and a first curing step for locally irradiating a non-adhesive surface of the resin member with infrared rays to cure a local portion of the adhesive.

The invention discloses a laser targeting local irradiation flux mapping method and device based on phase plate positioning, belongs to the field of laser targeting experiments, and aims to solve the problem that in existing optical element damage test analysis, flux data only takes average flux as a result, and target surface beam flux cannot correspond to damage points. The method comprises a calibration step for obtaining an affine transformation matrix and a step for carrying out a laser targeting experiment to obtain local irradiation flux of a target material, a phase plate is inserted between a lens of a targeting experiment light path and the target material, array damage points are formed on the rear surface of the target material, the affine transformation matrix is constructed, the phase plate is removed, and the target material local irradiation flux is obtained. Performing a laser targeting experiment by using the original experiment light path; mapping the target shooting laser beam near-field image to the target material damage image according to the affine transformation matrix, and superposing the target shooting laser beam near-field image and the target material damage image to obtain the position of the phase mark point corresponding to the target material damage point; and obtaining the local irradiation flux of laser targeting at the position of each damage point on the target material.

The invention discloses a method for observing local death of cyanobacteria cells by using a UV device, and relates to the technical field of cell research, and the method comprises the following steps: culturing cyanobacteria cells to a logarithmic phase to obtain a cyanobacteria sample; preparing an observation device; dropwise adding a cyanobacteria sample to the surface of the solidified culture medium, and air-drying and fixing; locally irradiating a sample area below the opening through a UV light source; sealing the sample through a cover glass and a second silicone rubber film sheet, and transferring the marking line to the cover glass; and observing the death process of cyanobacteria cells. Local precise UV stress of cyanobacteria protonema is realized by customizing a shading plate with a local opening, in-situ long-time stable observation is guaranteed by matching agar fixation and a sealed chamber design, and a continuous fluorescence microscopic imaging technology is combined; and the accurate visual tracking of the death time sequence, spatial distribution and death signal transmission process of different cells on the single protonema is realized.

This invention relates to the field of power regulation technology and discloses a far-infrared power regulation method and system based on biological characteristic data. The method involves: collecting surface temperatures of the target area in four directions (front, back, left, and right) and calculating the average surface temperature, maximum directional deviation, and heat concentration direction; calculating the far-infrared power regulation coefficient and generating a far-infrared local irradiation driving signal; when the heat concentration direction is the front or back direction, positively superimposing the electric field phase deflection onto the driving phase of the left and right electrode pairs; when the heat concentration direction is the left or right direction, negatively superimposing the electric field phase deflection onto the driving phase of the left and right electrode pairs, causing the combined effect direction of the cross-fields in the four directions to deviate from the heat concentration direction. Compared to existing single power regulation strategies, this invention has stronger spatial homogenization control capabilities for surface temperature and a more comprehensive active safety mechanism in complex control scenarios.

The invention provides a radioactive separation resin life prediction method and system based on machine learning, and relates to the technical field of radioactive waste liquid treatment.The method comprises the steps that real-time online monitoring data of radioactive separation resin in the operation process is obtained, the real-time on-line monitoring data comprises local adsorption capacity, local temperature and local irradiation dose acquired from three point locations, namely an upper point location, a middle point location and a lower point location, which are axially distributed on the resin column; on the basis of real-time online monitoring data, calculating to obtain a microstructure degradation quantitative index of the resin under the current working condition through the constructed microstructure degradation agent model; and performing feature fusion on the real-time online monitoring data and the microstructure degradation quantitative indexes to construct a fusion feature set. According to the invention, continuous, stable and safe operation of the radioactive waste liquid treatment and nuclide separation system is ensured.

The invention relates to the technical field of jaundice phototherapy, in particular to a portable neonatal jaundice phototherapy and body position adjustment integrated device which comprises a base and a placement box, and a phototherapy mechanism is arranged on the base; the phototherapy mechanism comprises a frame, the back wall of the frame is slidably connected with a closing plate, the frame is slidably connected with a plurality of moving frames, the moving frames are made of rubber and have shape plasticity, the moving frames are fixedly connected with mounting frames, the mounting frames are made of rigid materials, and the mounting frames are fixedly connected with the frame. The blue light lamp has the beneficial effects that the blue light lamp gets rid of the position constraint of a traditional preset connecting piece, rapid adjustment in the non-stop state is achieved, and no matter a lamp set is temporarily additionally arranged to strengthen local irradiation or a faulty lamp body is replaced, the operation is convenient, and the cost is low. The phototherapy jaundice removing can be efficiently completed without interrupting the phototherapy process, and the stability of the phototherapy jaundice removing efficiency is guaranteed.

A technical solution is presented for imaging an object containing a luminescent substance. A corresponding method (500) is based on a refinement loop. In each iteration of the refinement loop, a different spatial pattern (516-518, 524; 536-540, 546) is determined, a local illumination corresponding to the spatial pattern is applied to the object (520, 526; 542, 548), a component image is acquired in response to the local illumination (522, 528; 544, 550), and the component images are combined (530; 552) into a combined image. A corresponding system (100) is also presented. Furthermore, a computer program (400) and a corresponding computer program product are presented. A diagnostic method, a surgical method, and a therapeutic method based on the same solution are also presented.