39 results about "Animal anesthesia" patented technology

A wireless veterinary anesthesia monitoring system which provides a wireless anesthesia monitoring platform configured to locate veterinary anesthesia equipment and wireless veterinary surgical monitoring equipment in a single constructional form useful in the anesthesia and surgical monitoring of animals.

A veterinary anesthesia monitor system useful in establishing, maintaining, and reporting upon the anesthesia gas mixture delivered to or exhaled by a patient.

The invention relates to the technical field of medicines, and concretely relates to a blood dialysate detection method, and an application thereof in the pharmacokinetics-pharmacodynamics of a pulseactivating injection. The method comprises the following steps: preparing a conscious rat in-vivo microdialysis sampling device collected blood dialysate, analyzing the drug concentration of active ingredients in the blood dialysate by high performance liquid chromatography-triple quadrupole mass spectrography, and detecting the drug effect index NO in the blood dialysate by high performance liquid chromatography-fluorescence detection technique. A conscious rat in vivo microdialysis technique adopted in the invention overcomes the influences of animal anesthesia and blood loss on the pharmacokinetic and pharmacodynamic behaviors, is successfully used in the studying of the plasma concentration-time and drug effect-time relationships of the pulse activating injection against rat myocardialischemia, and can be used to establish a pharmacokinetic-pharmacodynamic combination model. A study result shows that when an appropriate blood endogenous biomarker is selected as a drug effect index, the conscious animal in vivo microdialysis sampling technique becomes an ideal tool for pharmacokinetic-pharmacodynamic combination studying.

The invention discloses a fixed anesthesia device for veterinary medicine, which comprises a rear fixing frame, a front fixing frame, a neck fixing sleeve and a drug feeding device. The lower end of the rear fixing frame is provided with a rear supporting leg, and a first A fixed sleeve, the left side of the front fixed frame is fixed with a connecting rod through a fixed pin, the lower end of the front fixed frame is provided with a front support leg, the front support leg is provided with a second fixed sleeve, and the upper end of the neck fixed sleeve is provided with The second rope is tied. The right side of the drug feeding device is provided with a blower, and the left side of the blower is connected with an atomizer. With fastening device. The veterinary fixed anesthesia device of the present invention solves the inconvenience of veterinarians to anesthetize larger animals, has a wide range of applications, avoids damage to animals caused by injection, and avoids harm to medical staff after being shocked, and has a good anesthesia effect. efficient.

The invention discloses a cerebrospinal fluid collection method. The method comprises the following steps: (1) carrying out animal anesthesia; (2) carrying out shaving and disinfection of a lumbar region of the back of an animal; (3) coating the puncture part of the animal with a wound towel; (4) carrying out puncture on the lumbar region of the back of the animal; (5) when a syringe needle punctures a subarachnoid space of the animal and generates a fall feeling, stopping inserting the syringe needle; (6) connecting an injector and collecting animal cerebrospinal fluid; and (7) pulling out the syringe needle after operation is ended, pressing the puncture part with a dry cotton ball, putting the animal back to a cage, and monitoring the animal until the animal is sober from anesthesia and the action is normal. The cerebrospinal fluid of the animal is collected through a lumbar puncture method; and the cerebrospinal fluid collection method is small in wound to the animal, simple and fast to operate and low in demands on equipment, materials and places.

A valve is provided for controlling the flow of gas through an anesthesia or respiratory breathing circuit. The valve includes a valve body having a first port, a second port, and a third port. The third port includes a flow restrictor for restricting the flow of gas through the third port. A valve closing member is provided that is moveable between an open position where gas can flow through the third port, and a closed position. In the closed position, gas is prevented from flowing through the third port.

The invention belongs to the technical field of experimental devices and discloses an experimental animal anesthetizing and killing device and a use method thereof. The experimental animal anesthetizing and killing device is provided with an anesthetizing box body, wherein an animal inlet is welded above the anesthetizing box body, the left side of the anesthetizing box body is welded with two gasinlet pipes, the two gas inlet pipes are respectively provided with an air sucking pump and an anesthetic gas pump which are respectively provided with an air tank flow meter and an anesthetic gas flow meter. The tail ends of the gas inlet pipes are respectively connected with an air tank and an anesthetic gas tank through pistons; the right side of the anesthetizing box body is welded and provided with a gas inlet pipe, the gas outlet pipe is welded and connected with a gas sucking pipe, and a fan is installed on the gas sucking pump through screws. The right side of the gas sucking pump isprovided with a gas collecting port, and the gas collecting port is connected with a gas collecting tank through the gas outlet pipe. The experimental animal anesthetizing and killing device adjusts the content of anesthetic gas, improves the anesthetizing speed and relieves the pain of an experimental animal according to the actual situation of the experimental animal. After an experiment is completed, residual anesthetic gas is blown out and collected by sucking air, and air pollution is reduced.

A veterinary anesthesia monitor system useful in establishing, maintaining, and reporting upon the anesthesia gas mixture delivered to or exhaled by a patient.

The invention discloses a traditional Chinese medicine composition for animal anesthesia and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal material slices in parts by weight: 5 to 30 parts of flos daturae, 4 to 13 parts of flos rhododendri, 7 to 15 parts of radix aconiti carmichaeli, 1 to8 parts of semen hyoscyami, 3 to 7 parts of venenum bufonis and 2 to 5 parts of rhizoma acori tatarinowii. The preparation method comprises the following steps: after pulverizing the six medicinal material slices through an ultrafine pulverizer, immersing the medicinal materials for 3h by utilizing warm water with the temperature of 60 DEG C, and filtering by utilizing double-layer filter paper; then boiling a concentrated solution extracted through ethanol for three times and sterilizing; centrifuging and taking supernatant; regulating the supernatant to be isotonic by utilizing 0.9 percent sodium chloride and making the volume constant; regulating the pH (Potential of Hydrogen) to 6.8 to 7.0; filtering by utilizing a micropore filter membrane and sterilizing; sterilely filling to form medicinal injection for later use. The traditional Chinese medicine composition disclosed by the invention has relatively good calming, pain easing and anesthetic actions and has an obvious inhibition effect on a central nervous system, and the effective rate reaches 66.7 percent to 93.3 percent; the traditional Chinese medicine composition has high safety performance, basically has no toxic and side effects and no residues, is suitable for clinical popularization and application, and can be industrially produced in a large scale.

The invention relates to the field of animal anesthesia tools, in particular to a flying type animal anesthesia injection equipment. The invention provides a flying animal anesthesia injection equipment, and aims to solve the problems that an anesthesia gun cannot guarantee accurate injection depth and cannot shoot an animal to cause attack of the animal to a human body. The invention discloses a flying type animal anesthesia injection equipment which comprises a working box body, a flying carrier used for controlling the working box body to move is fixedly arranged on the working box body, a working cavity is formed in the working box body, and an injection equipment capable of moving and controlling anesthetic filling and releasing through a piston mechanism is arranged in the working cavity.

The method comprises the following steps: detecting whether the veterinary anaesthesia machine enters a leakage self-inspection state, and if the veterinary anaesthesia machine enters the leakage self-inspection state, displaying a guide interface; displaying guide information corresponding to the currently selected test ventilation mode in the information display area; detecting whether a mode switching instruction, a leakage self-checking instruction or a guiding instruction input by a user is received or not; switching the test ventilation mode based on the mode switching instruction, and replacing the content displayed in the information display area with guidance information corresponding to the switched test ventilation mode; starting gas leakage self-inspection based on the leakage self-inspection instruction, obtaining a leakage self-inspection result, replacing the guide information in the information display area with self-inspection result information, and detecting whether a mode switching instruction input by the user is received again; and replacing the guiding interface with a preset operation interface based on the guiding instruction. Through the guidance method, the user can be effectively guided to complete the operation steps when the system performs self-inspection.

The invention relates to a method for anaesthetizing animals before slaughter, by the anaesthetic action of gases or gas mixtures,method operating in “batch” mode in which the live animals, preferably put together in one or more cages, are placed in a lock chamber for treatment where the animals are brought into contact with anaesthetic gas, following a cycle comprising several steps characterized by different contents of anaesthetic gas, characterized in that at least one of the steps is carried out using gas recovered from the lock chamber and stored in at least one capacity (2, No. 1, No. 2 etc.) for temporary storage having a variable volume.

The invention discloses a target area adjustable type batch animal ionizing radiation local irradiation fixing and shielding device. The device comprises an animal fixing part and a ray shielding part, wherein the animal fixing part comprises an animal anesthesia fixing table, and the ray shielding part comprises a ray shielding table; an anesthesia induction box and a batch animal fixing box arearranged on the table top of the animal anesthesia fixing table; a transverse adjusting and controlling shielding device, an up-down adjusting and controlling shielding device and a transverse-longitudinal scale division plate are arranged on the table top of the ray shielding table; the transverse adjusting and controlling shielding device blocks redundant rays in the horizontal direction, and afirst gap with the adjustable size and position in the direction perpendicular to the ground is exposed; the up-down adjusting and controlling shielding device blocks redundant rays in the direction parallel to the ground, and a second gap with the adjustable size and position in the direction parallel to the ground is exposed; a rectangular area, namely an irradiation field, is formed at the intersection of the two gaps; through stepped connection, leakage caused when the rays pass through the transverse arrangement position of a shielding block is blocked, and incomplete blocking is avoided;and the position and area of the irradiation area are flexible, adjustable and accurate in irradiation.

The invention discloses an animal experiment anesthesia toxic gas utilization treatment and purification device. The device comprises an animal anesthesia chamber with an animal throwing opening in the top. A diethyl ether concentration measuring instrument and a horizontal metal grid net used for bearing animals are installed in the animal anesthesia chamber. A diethyl ether volatilization chamber is arranged below the metal grid net in the animal anesthesia chamber; a diethyl ether dispenser is arranged outside the animal anesthesia chamber; the diethyl ether dispenser is communicated with the diethyl ether volatilization chamber through an ascending pipe with a diethyl ether inlet control valve; the diethyl ether volatilization chamber is further communicated with an air inlet pipelinewith an air inlet control valve, a plurality of diethyl ether exhaust ports are formed in the animal anesthesia chamber and located above the metal grid mesh, the diethyl ether exhaust ports are connected to a gas collecting pipe through pipelines with diethyl ether outlet control valves, the gas collecting pipe is communicated with a purification treatment tank, and a draught fan is arranged on the communicating pipeline. The system device can ensure that diethyl ether gas can be fully utilized in the whole process and cannot be diffused to the external environment, and the problems in animalanesthesia teaching experiments at present are thoroughly solved.

The invention provides an operation tray for fixing murine. The operation tray comprises a chassis; the chassis is provided with in-place grooves; a dirt receiving box is arranged at the end of the chassis; retention bands are arranged on the in-place grooves; the retention bands are provided with magic tapes; dirt discharge grooves are arranged at the lower parts of the in-place grooves; and thedirt discharge grooves are communicated with the dirt receiving box. According to the operation tray for fixing murine, which is provided by the invention, by designing the dirt discharge groove and adirt receiving groove, excrements, such as urine, faeces and the like, of murine during anesthesia can be timely collected, and the possibility of accidental infection on an animal after an experiment is reduced; by designing fixing bands convenient to fix and disassemble, the animal during anesthesia can be rapidly fixed or taken down, so that excessive injection of an animal anaesthetic can beavoided, and safety of the experiment is promoted; and by designing the in-place grooves, the operation tray can be suitable for the body shape of murine better, and an operator does not need to worryabout unnecessary damage or influence on the operation progress, which is caused by movement of the body of murine.

The invention relates to the technical field of experimental animals, and in particular to a device for fixing whole body tissue by perfusion of an animal heart. The device for fixing the whole body tissue by perfusion of the animal heart comprises a pressure pump, a buffer bottle, a washing liquid bottle and a fixing liquid bottle; the pressure pump is connected with the air inlet end of the buffer bottle through an air guide pipe; the air inlet end of the washing liquid bottle and the air inlet end of the fixing liquid bottle are connected with the air outlet end of the buffer bottle separately through corresponding air supply pipes; and the air outlet end of the washing liquid bottle and the air outlet end of the fixing liquid bottle are connected with liquid outlet pipes. By using thedevice, animal whole body tissue cells can be quickly and efficiently fixed synchronously through animal anesthesia and animal thoracotomy; and meanwhile, more complete tissue proteins and nucleic acid molecules can be obtained simultaneously to provide high-quality experimental specimens for later experiments.

The invention discloses a preparation method of an animal model with high expression of genes transfected through an endotracheal pathway in lung tissues. The preparation method comprises the following steps: (1) constructing a recombinant virus vector carrying a vascular endothelial growth factor A, and adjusting a virus titer to 0.5 to 2x10<11>PFU / mL; and (2) anesthetizing an animal, hanging andfixing the animal, irradiating the neck of the animal, opening the oral cavity of the animal, inserting a tracheal catheter, injecting viruses into lung tissues of the animal through the tracheal catheter, connecting the animal with a breathing machine until the animal is awake, and finally pulling out the tracheal catheter. The invention constructs an animal model that achieves targeted transfection of a recombinant adenovirus vector in the lung tissue of newborn rats through an intratracheal route, the adenovirus vector is transfected into the trachea with a suitable amount of virus and theefficiency of transfection to other organs other than the lung is low, and transfection targeting is improved.

The invention discloses an animal anesthesia mask assembly and relates to the technical field of animal operation auxiliary equipment. The animal anesthesia mask assembly includes a mask body, an air inlet and an air outlet, both of which are in communication with the inside of the mask body, and the air inlet is configured to introduce gas mixed with anesthetic components into the mask body, It also includes a mouth stick, which is separated from the mask body, and one end of the mouth stick can be inserted into the mouth of the animal through the through hole arranged on the mask body and fixed by the teeth of the animal. The animal anesthesia mask assembly proposed by the present invention has simple structure and convenient operation, and can keep the posture and posture of the animal's head still during the operation.

The invention discloses a construction method of a glaucoma-ciliary cyclitis syndrome animal model and the animal model, and the construction method comprises the following steps: 1) animal anesthesia: anesthetizing an animal, and keeping eyeballs of the animal to be slightly convex; 2) eye anesthesia: performing surface anesthesia on the left eye and / or the right eye of the animal as a tested eye; and 3) virus infection: injecting the MCMV gene recombinant virus expressing the EGFP into the anterior chamber through the cornea center of an animal test eye, and establishing an animal model infected by the MCMV. According to the construction method of the animal model of the glaucoma-ciliary cyclitis syndrome, the mouse cytomegalovirus is injected into the anterior chamber of the eye of the mouse, the PSS animal model is constructed, and an effective animal model is provided for exploration of pathogenesis of the PSS.

The invention discloses an anesthetic gas recovery device for an animal anesthesia machine. The anesthetic gas recovery device comprises a device body, the device body comprises a bottom shell, a top cover, a connecting opening, an access pipe, a filter element device, an exhaust fan and a support frame, the bottom shell is arranged at the bottom of the device body, the top of the bottom shell is connected with the top cover in a threaded manner, and the connecting opening is arranged at the top of the top cover. The top of the connecting opening is connected with one end of the connecting pipe through threads, an exhaust fan and the filter element device are arranged in the bottom shell, the exhaust fan is located at the bottom of the filter element device, and two sets of supporting frames which are symmetrically distributed at equal intervals are welded to the side edge of the bottom of the bottom shell. The anesthetic gas recovery device is provided with the filter element device, the filter element device can efficiently filter anesthetic gas, and the anesthetic gas recovery device is small in size, convenient to carry by a worker, simple in structure and convenient to disassemble and clean by the worker, so that the anesthetic gas filtering effect is improved.

The invention belongs to the field of animal anesthesia, and particularly relates to an animal anesthesia machine. Comprising a bottom plate, a stand column is fixedly connected to the top end of the bottom plate, a cross beam is fixedly connected to the top end of the stand column, an anesthesia loop block is fixedly connected to one side of the outer wall of the cross beam, a switching valve is arranged on one side of the outer wall of the anesthesia loop block, and a soda lime box is fixedly connected to the bottom end of the anesthesia loop block. An anesthesia loop block is connected into the module, then a conventional circulating breathing loop pipe is connected into an air inlet port and an air outlet port of the module, a non-rebreathing type direct anesthesia mode can be achieved, when the direct current module is used, the breathing loop pipe applied in the rebreathing type circulating anesthesia mode can be shared, and the purpose that under low air resistance, the direct current module can be used for direct anesthesia is effectively achieved. The invention relates to non-rebreathing type direct anesthesia of a low dead space of a small animal.

The invention relates to a working system suitable for acupuncture point stimulation in small animal experiments. The working system comprises a miniature oxygen generator, an anesthesia system, an anesthetic flow control support, an air outlet and return pipe, a tail gas recovery processing tank and an electro-acupuncture stimulator; the output end of the miniature oxygen generator is connected with the input end of the anesthesia system, the output end of the anesthesia system is connected with the input end of the anesthetic flow control support, the output end of the anesthetic flow control support is connected with a first end of the air outlet and return pipe, and a second end of the air outlet and return pipe is connected with the tail gas recovery processing tank; a third end of the air outlet and return pipe supplies oxygen to the animal, and the electro-acupuncture stimulator is connected with acupuncture points of an animal. According to the invention, a low-concentration gaseous anesthesia technology is adopted, it is guaranteed that the anesthesia level of animals is continuous and constant in the whole experiment process, the potential influence of the stress state caused by manual binding and constraint on the experiment result is avoided, the acupuncture stimulation time is controllable, and the animals can rapidly wake up and freely move after the experiment is finished.

The anesthesia breathing system comprises a driving gas mechanism, a fresh gas mechanism and an anesthesia breathing machine, the fresh gas mechanism is used for feeding fresh gas with anesthetic gas into the anesthesia breathing machine, and the anesthetic breathing machine is used for feeding the fresh gas with the anesthetic gas into the anesthesia breathing machine. The driving gas mechanism is used for pushing fresh gas in the anesthesia respirator to a patient; wherein the fresh gas mechanism comprises an oxygen generator and a gas storage tank, the oxygen generator is used for preparing oxygen, the gas storage tank is connected between the oxygen generator and the anesthesia respirator, and the gas storage tank is used for storing the oxygen prepared by the oxygen generator and supplying the oxygen to the anesthesia respirator. According to the anesthesia breathing system disclosed by the invention, the gas storage tank is arranged between the oxygen generator and the anesthesia breathing machine, and the gas storage tank stores oxygen prepared by the oxygen generator, so that the situation that the rescue opportunity of a patient is missed due to insufficient gas supply of the oxygen generator when the anesthesia breathing machine needs to quickly supply oxygen is prevented.

The invention discloses an experimental device for animal anesthesia, and relates to the technical field of animal experimental anesthesia. The experimental device for animal anesthesia comprises a box body, wherein one side of the top of the box body is penetrated with a toothed slot plate; the top of the toothed slot plate is fixedly connected with a baffle plate; the bottom of the toothed slotplate is fixedly connected with a connecting plate; two sides of the bottom of the connecting plate are fixedly connected with a fixing block; and the bottom of the fixing block is fixedly connected with a sliding slot. The experimental device for animal anesthesia can adjust the direction of spraying anesthetic liquid from top to bottom and from left to right, and animals of different sizes can be anesthetized, so that the anesthetic device can be used more widely; Before the animals are completely anesthetized, animals are easy to move, and the anesthetic nozzle can follow the animals for anesthesia, thus saving the time of anesthesia, greatly improving the work efficiency, atomizing the anesthetic liquid, enabling the animals to be anesthetized to absorb the anesthetic liquid more quickly, accelerating the anesthetic efficiency of the animals, and better protecting the internal structure of the device.

The invention discloses a dose-adjustable inhalation continuous anesthesia device for small and medium-sized animals, and belongs to the technical field of animal anesthesia. The anesthesia device comprises a double-ball air supply device, an anesthetic gasification device, an anesthetic supplement device, an anesthesia tube, a fixing device, and an anesthetic exhaust gas absorption device. The double-ball air supply device, the anesthetic supplement device and the anesthesia tube are all connected with the anesthetic gasification device. The anesthesia tube has a transparent valve. The transparent valve allows a front leg of a small and medium-sized animal to enter the anesthesia tube without being easily withdrawn. The anesthetic gasification device is provided with an anesthetic and a non-volatile liquid which is miscible with the anesthetic. By controlling the concentration of anesthetic gas entering the anesthesia tube, the animal is kept under anesthesia by continuously inhalingthe anesthetic gas within a certain concentration range, so that the animal can be kept anesthetized during an experiment, and is not over- or too lightly anesthetized, so that the experiment can be carried out better. The anesthesia device is simple to manufacture, convenient to operate, economical and practical, and convenient for popularization and application.

The invention relates to a portable inhalation animal anesthesia device and use methods thereof. The device comprises a breathing mask, a volatilizer, an induction anesthesia box, and airway tube. Theuse methods include: used alone or in conjunction with anesthesia machine. When the device is used alone, volatile anesthetic drugs is added into the induction anesthesia box and the volatile device,and animal is placed into the induction anesthesia box to perform induction anesthesia. The breathing mask is connected to the volatilizer through the airway tube, and the induction anesthetized animal is taken out of the induction anesthesia box. The breathing mask is mounted to muzzle and nose of the animal. The animal continues to inhale the gas mixed with the anesthetic under the action of the vaporizer to maintain the continuous anesthesia. When the device is used in conjunction with an anesthesia machine, the interface that the anesthesia machine output anesthesia gas is connected to the breathing mask with the airway tube, and the induction anesthesia box is connected to the anesthesia machine in the same way. The breathing mask is put on muzzle and nose of the animal. The animal is kept continuous anesthesia state by keeping inhaling anesthesia gas.

The invention discloses a model animal anesthesia-free directional embedding method and system, the system comprises a zebra fish micro-fluidic chip and a droplet array chip, the zebra fish micro-fluidic chip comprises a micro-fluidic chip substrate and a cover plate; the micro-fluidic chip substrate and the cover plate are connected in a non-permanent combination manner. The micro-fluidic chip can realize the preparation of the zebra fish capsule only by simple cooling, and the obtained zebra fish capsule has the same activity as non-fixed zebra fish, and has high survival rate. The zebra fish anesthesia-free directional embedding medicine screening system is simple to construct, small in size, convenient to use, low in cost and free of assistance of peripheral equipment, the medicine screening experiment dosage is reduced from mL level to mu L level, and high throughput, multiple phenotypes and low consumption in the real sense are achieved.

The invention belongs to the technical field of animal treatment, particularly relates to a trachea cannula special for animals and matched with an animal respiration anesthesia machine, and aims to solve the problem that a tracheal catheter for animal anesthesia is not tightly connected with a cannula, the following scheme is provided: the trachea cannula comprises a respiration anesthesia machine body and a catheter body connected to the respiration anesthesia machine body, one end of the catheter body is fixedly connected with a sleeve, the inner wall of the sleeve is provided with threads and connected with a connector through the threads, one end of the connector is provided with a rubber head, the inner wall of the catheter body is provided with an inner tube, the space between the inner tube and the catheter body is filled with filling liquid, an air bag is arranged on the circumferential outer wall of a cannula body, and a connecting pipe is fixedly connected into the air bag. By arranging the connector and the rubber head, after the connector extends into the inner wall of the sleeve, the rubber head is extruded, so that the rubber head is tightly attached to the threaded end of the inner wall of the sleeve, and gas is prevented from leaking from the joint of the catheter body and the cannula body.