49 results about "Radiation proctitis" patented technology

The invention discloses an American cockroach medicinal composition for curing ulcers or ulcerative inflammation. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and montmorillonite powder. The weight part ratio of the American cockroach extract to the montmorillonite powder is equal to 0.8-1.2:0.5-6. A preparation method of the American cockroach medicinal composition for curing the ulcers or the ulcerative inflammation comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and has obvious effects of effectively curing diseases such as oral ulcers, recurrent aphthous ulcers, oral lichen planus, oral mucosal injury (behcet disease, herpes simplex, leukoplakia, discoid lupus erythematosus, hand-foot-and-mouth disease, scalds, chemotherapy, radiotherapy and the like) caused by various reasons, reflux esophagitis, eophageal ucers, radiation esophagitis, ulcerative colitis, radiation proctitis, and diarrhea, and hematochezia with mucosal injury, and the like.

The invention relates to a Chinese medicinal composition for treating radiation proctitis. The composition is characterized by consisting of the following medicaments: 4 to 6 grams of phellodendron, 2 to 4 grams of atractylodes rhizome, 6 to 8 grams of dried rehmannia root, 4 to 6 grams of dendrobe, 2 to 4 grams of dwarf lilyturf root, 6 to 8 grams of pilose asiabell root, 6 to 8 grams of Chinese yam, 4 to 6 grams of tuckahoe, 4 to 6 grams of suberect spatholobus stem, 4 to 6 grams of Chinese angelica, 2 to 4 grams of pseudo-ginseng, 4 to 6 grams of agrimony, 4 to 6 grams of red peony root, 2 to 4 grams of gallnut, 4 to 6 grams of fructus amomi, 4 to 6 grams of red halloysite, 4 to 6 grams of myrobalan and 4 to 6 grams of liquorice. The composition has the advantages of clearing heat and detoxifying, strengthening spleen and eliminating dampness, removing stasis and dredging collaterals, inducing astringency and arresting discharge. Diseases are dialectically treated according to different symptoms in clinic. The Chinese medicinal composition is suitable for treating acute and chronic radiation proctitis.

The invention belongs to the technology field of traditional Chinese medicine, in particular to an enema for the treatment of radioactive rectitis, which can solve the problem that the prior art has no ideal drug and effective method for the radioactive rectitis. The enema for the treatment of the radioactive rectitis is prepared by the raw materials with the following weight ratio of 3 to 6g of sanchi, 3 to 6g of catechu, 5 to 10g of donkey-hide glue, 10 to 30g of common bletilla pseudobulb, 15 to 45g of garden burnet root, 6 to 9g of rhubarb and 15 to 30g of hairyvein agrimonia herb and bud. The enema of the invention can significantly ease mucous bloody stool, diarrhea, abdominal pain, tenesmus, anal burning pain and bearing-down pain and other clinical symptoms, improve the positive of fecal occult blood test, the colonoscopy mucous membrane lesions and the radiation injuries and improve the quality of lives of the patients; and the enema has low recurrence rate, reliable efficacy, stable function, no toxicity or side effects, thus being the more satisfied drug for the treatment of the radioactive rectitis.

The invention discloses a Chinese traditional medicine composition for oral administration to treat radiation proctitis, belonging to a field of Chinese traditional medicine. The raw medicinal materials comprising the effective components of the composition are prepared with the weight proportion as follows: 30-60g agrimony, 20-30g humulus scandens, 10-15g ginseng, 20-30g yam, 15-30g Coix seed, 15-30g hedyotis diffusa willd, 15-30g Garden Burnet, 6-10g cinnamon, 3-6g panax notoginseng, 10-15g allium macrostemon Bunge, 15-24g white peony root, 10-15g ebony, 10-15g catechu, 10-15g toasted hedgehog skin and 6-10g liquorice. All the materials are prepared to be soup for warm administration twice a day in the morning and in the afternoon. All the materials in the invention are compatible to play a role of invigorating spleen and kidney, clearing intestines and removing dampness, dispelling diarrhea and stopping diarrhea with a remarkable clinical curative effect, while at the same time, the composition adopts a pure Chinese traditional medicine preparation, which has a low incidence of adverse reactions.

The invention relates to a traditional Chinese medicine used for treating radiation proctitis. The traditional Chinese medicine is characterized in that: the medicine is prepared from raw medicines of: 8 to 10g of cape jasmine, 6 to 8g of lightyellow sophora root, 6 to 10g of philippine violet herb, 8 to 10g of figwort, 6 to 8g of reed rhizome, 6 to 8g of upright ladybell root, 6 to 8g of largehead atractylodes rhizome, 8 to 10g of common anemarrhena, 6 to 9g of rehmannia dride rhizome, 6 to 9g of hairyvein agrimonia herb, 8 to 10g of ligusticum, 6 to 8g of turkey-tail, 6 to 8g of ophicalcite, 6 to 8g of red halloysite, 6 to 8g of callicarpa pedunculata, 6 to 8g of potentilla discolor bunge, 6 to 8g of common andrographis herb, 6 to 8g of ligusticum chuanxiong hort, and 4 to 6g of licorice. The purposes of the traditional Chinese medicine are heat clearing, detoxicating, yin nourishing, pathogen eliminating, bleeding relieving with astringents, wound healing, and pain relieving. With the traditional Chinese medicine, tumor patients can smoothly finish radiotherapy tasks. The traditional Chinese medicine has advantages of simple formulation, convenient application, good curative effect, low price, and no toxic or side-effect. The traditional Chinese medicine is applied clinically according to differentiated symptoms, and is suitable for patients of acute and chronic radiation proctitis. When in use, there is an announcement that: when bleeding is not occurred or is stopped after treating, the application of hairyvein agrimonia herb is stopped.

The invention discloses an enema for treating radiation proctitis. The radiation proctitis belongs to categories of diarrhea and dysentery of traditional Chinese medicine. The causes of the radiation proctitis are insufficient of healthy qi, downward flow of damp-heat, asthenia in origin and asthenia in superficiality, and the radiation proctitis and the causes interact as both cause and effect. Consequently, the enema is made of traditional Chinese medicine narcissus, salvia chinensis, meadowrue root and rhizome, semen cassia, Chinese toona root-barks, trollflowers, beautyberry leaves, Japanese thistle herbs, lotus leaves, pagoda tree pods, mulberries, bighead atractylodes thizome, longan seeds and honey which have the functions of clearing away heat and toxic materials, subsiding a swelling and stopping bleeding, and replenishing qi and enriching blood. Through clinical tests of a hospital, total effective rate of a treatment group is 91.3% and is superior to that, which is 78.3%, of a control group. The enema for treating radiation proctitis has no side effect and is worth of clinical popularization and application.

The invention provides traditional Chinese medicine composition used for treating radiation proctitis and a preparation method thereof. The traditional Chinese medicine composition is composed of radix astragali, parched white atractylodes rhizome, radix angelicae sinensis, radix rehmanniae, fried radix paeoniae alba, radix pulsatillae, dandelion, fried smoked plum, elecampane, betel nuts, rhizoma coptidis, and radix glycyrrhizae. On the basis of the formula, the invention provides a medicine formula capable of intensively treating radiation proctitis with a symptom of hematochezia, namely, 20 parts of charred sanguisorba, 10 parts of bletilla striata, 10 parts of setose thistle, and 10 parts of field thistle are added in the traditional Chinese medicine composition. On the basis of the formula, the invention further provides a medicine formula capable of intensively treating radiation proctitis with a symptom of diarrhea, namely, 10 parts of fructus aurantii and 10 parts of Mangnolia Officinalis are added in the traditional Chinese medicine composition. On the basis of the formula, the invention further provides a medicine formula capable of intensively treating radiation proctitis with a symptom of stomachache, namely, 10 parts of rhizoma corydalis and 15 parts of red radix polygoni multiflori are added in the traditional Chinese medicine composition. The traditional Chinese medicine composition has the advantages of being capable of treating radiation proctitis quickly and effectively and is better in therapeutic effect than combination of Chinese traditional medicine and western medicine and pure western medicine.

The invention discloses a Chinese medicinal preparation for treating chronic radiation proctitis. The traditional Chinese medicine considers that the radiation proctitis is caused by body irradiation of the radioactive rays as fire toxin evil invasion, so that the body fluid is lost, the stomach and intestine are hot and phlegm stagnation exists, and for treating the disease, the medicine for clearing heat and promoting dieresis, promoting blood and removing stasis and removing the harm in intestine can be used. Therefore, calathodes, souliea vaginata, japanese claw fern herb, wilson barberry, patrinia, verbena, gynostemma pentaphylla, rhizoma polygonati, bighead atractylodes rhizome, Chinese holly root, beautyberry leaf, securidaca inappendiculata hassk and licorice are decocted with water into decoction. The total effective rate is 96.4% shown by clinical trials in the hospital and is obviously superior to that of the control group.

The invention discloses a Chinese medicinal enema for treating cervical cancer chronic radiation proctitis. The Chinese medicine thinks that radioactive ray is evil of toxic heat, the heat evil is stagnated in the rectums, the invaginated large intestine fights with qi and blood, the qi movement is disordered, the intestinal collaterals are injured and the conduction is abnormal, so that the symptoms of hemafecia and difficult defecation occur. Therefore, the Chinese medicinal enema is prepared by selecting Chinese medicaments with the functions of clearing away heat and toxic materials, astringing to stop bleeding, anti-swelling and promoting granulation, tonifying qi and spleen as the raw materials, such as potentilla chinensis, radix tinosporae, archangiopteris, tortuous knotweed root, white pomegranate petal, limonitum, ferrugineous ask bark, natsu gumi, puberulous glochidion branchlet and leaf, calathodes, silverweed cinquefoil root, honeysuckle root, bighead atractylodes rhizome and gorgon fruit; and the Chinese medicaments are prepared into the enema in a drug preparing laboratory of our hospital. By clinical experiments, the total effective rate reaches 97.8%, adverse response is avoided, and the cervical cancer chronic radiation proctitis does not recur after following up for half a year.

The invention provides a traditional Chinese medicine composition for treating radiation proctitis, which is quick to take effect, good in effect and free from toxic and side effects and a preparation method thereof. The traditional Chinese medicine composition for treating radiation proctitis comprises the following raw material medicines by weight: 10-15g of Astilbe chinensis, 6-9g of dutchmanspipe root, 6-8g of Angelica sinensis, 12-15g of Ligusticum wallichii, 6-8g of Adenophora stricta, 10-15g of white hyacinth Bean, 6-8g of Rhizoma Atractylodis Macrocephalae, 9-15g of brookside astilbe, 9-15g of Bergenia crassifolia, 12-15g of medlar, 10-12g of Eclipta prostrate, 4-6g of liquorice, 10-15g of radix paeoniae alba, 15-30g of hairyvein agrimony, 15-20g of Cucurbitaceae, 15-18g of red umbilicaria, 9-12g of polygonum cillinerve ohwi, 5-10g of colla corii asini, 6-8g of pseudo-ginseng, 8-10g of radix scrophulariae, 10-15g of Scutellaria baicalensis and 9-12g of corydalis tuber. The preparation method of the traditional Chinese medicine composition comprises the following steps of: weighing the raw material medicines except pseudo-ginseng and colla corii asini; placing the raw material medicines in a marmite; adding 800ml of water to soak the raw material medicines; soaking for 60 minutes; decocting for 30 minutes by soft fire; filtering and obtaining a medicine liquid; then, adding 600ml of water, decocting for 20 minutes by soft fire, and obtaining a medicine liquid; grinding pseudo-ginseng and colla corii asini to fine powder, and then mixing the medicine liquids to obtain the composition.

The invention discloses a traditional Chinese medicine preparation for treating radiation proctitis. According to the traditional Chinese medicine, the main pathogenesis of a radioactive damage is excessive toxic heat; and the pathogenesis is heat toxin accumulation in yin portion, bad predestination of liver and kidney, and deficiency and damage of qi. Therefore, the traditional Chinese medicines of Chinese snapweed stem and leaf, henry hemsleya root, Japanese mazus herb, golden cypress, humifuse euphorbia herb, beautyberry leaf, henry clematis root, caudate sweetleaf leaf, procumbent indian mallow root, silverweed cinquefoil root, astragalus membranaceus and red halloysite are selected to be decocted into decoction. By our clinical trials, the total effective rate is 95.2%; and the indexes such as stomachache, defecate frequency, stool property, abnormal defecation, mucous stool and the like are obviously improved, and superior to those of a control group.

The invention belongs to the technology field of traditional Chinese medicine, in particular to an enema for the treatment of radioactive rectitis, which can solve the problem that the prior art has no ideal drug and effective method for the radioactive rectitis. The enema for the treatment of the radioactive rectitis is prepared by the raw materials with the following weight ratio of 3 to 6g of sanchi, 3 to 6g of catechu, 5 to 10g of donkey-hide glue, 10 to 30g of common bletilla pseudobulb, 15 to 45g of garden burnet root, 6 to 9g of rhubarb and 15 to 30g of hairyvein agrimonia herb and bud. The enema of the invention can significantly ease mucous bloody stool, diarrhea, abdominal pain, tenesmus, anal burning pain and bearing-down pain and other clinical symptoms, improve the positive of fecal occult blood test, the colonoscopy mucous membrane lesions and the radiation injuries and improve the quality of lives of the patients; and the enema has low recurrence rate, reliable efficacy, stable function, no toxicity or side effects, thus being the more satisfied drug for the treatment of the radioactive rectitis.

The invention discloses a traditional Chinese medicine preparation for treating radiation proctitis. According to the traditional Chinese medicine, the main pathogenesis of a radioactive damage is excessive toxic heat; and the pathogenesis is heat toxin accumulation in yin portion, bad predestination of liver and kidney, and deficiency and damage of qi. Therefore, the traditional Chinese medicines of Chinese snapweed stem and leaf, henry hemsleya root, Japanese mazus herb, golden cypress, humifuse euphorbia herb, beautyberry leaf, henry clematis root, caudate sweetleaf leaf, procumbent indian mallow root, silverweed cinquefoil root, astragalus membranaceus and red halloysite are selected to be decocted into decoction. By our clinical trials, the total effective rate is 95.2%; and the indexes such as stomachache, defecate frequency, stool property, abnormal defecation, mucous stool and the like are obviously improved, and superior to those of a control group.

The invention relates to a Chinese medicinal preparation for treating radiation proctitis, and the Chinese medicinal preparation is characterized by comprising the following medicaments in parts by weight: 8 to 10 parts of American ginseng, 6 to 8 parts of astragalus, 8 to 10 parts of Chinese angelica, 8 to 12 parts of figwort root, 8 to 10 parts of rehmannia root, 6 to 8 parts of bark of tree peony, 8 to 10 parts of medicine terminalia fruit, 4 to 6 parts of round cardamom, 6 to 8 parts of smoked plum, 6 to 8 parts of pseudo-ginseng, 4 to 6 parts of bletilla striata, and 6 to 8 parts of tuckahoe. After being selected, mixed and soaked in water, the raw material medicaments are decocted, the decoction containing 200ml in each dosage is taken 100ml orally twice a day, 10 days is taken as a course of treatment, and the decoction is taken for three courses of treatment. The Chinese medicinal preparation has the advantages of reinforcing vital energy and nourishing yin, clearing heat and promoting fluid, enriching blood and promoting blood circulation, as well as astringing to arrest bleeding. The Chinese medicinal preparation can be used for clinical treatment based on an overall analysis of illness and condition of a patient according to different symptoms, has the advantages of convenient material drawing, easy preparation, economy and low price, as well as no toxic or side effect, and is suitable for treating patients suffering from acute and chronic radiation proctitis.

The invention discloses medicine liquor for treating cervical cancer complication radiation proctitis through coloclysis. The medicine liquor is prepared from the following traditional Chinese medicinal materials in parts by weight: 21-29 parts of pomegranate bark, 9-15 parts of eclipta, 7-12 parts of the root bark of shaggy-fruited dittany, 5-10 parts of Chinese tamarisk twig, 7-12 parts of madder, 9-15 parts of rhizoma cibotii, 12-20 parts of the root of Chinese pulsatilla, 9-15 parts of amur corktree bark, 9-15 parts of herba siegesbeckiae, and 9-15 parts of hairyvein agrimony. The medicine liquor has multiple effects of astringing, relieving pain, stopping bleeding, diminishing inflammation and protecting intestinal mucosa, and is particularly suitable for treating the patients suffering from radiation proctitis; the preparation of the compound clysis fluid is simple, and low in cost.

The invention discloses a gastric ulcer composition containing an extract of periplaneta americana and a preparation method thereof. The gastric ulcer composition comprises, by mass, 0.1-20 parts of water-soluble extract of periplaneta americana, 3-15 parts of semen oroxyli, 10-50 parts of caulis perillae acutae, 10-30 parts of ossa sepiae, 10-60 parts of radix paeoniae alba, 10-60 parts of rhizoma corydalis, 10-30 parts of pericarpium citri reticulatae, 10-50 parts of poria cocos, 10-50 parts of radix puerariae, 5-25 parts of panax notoginseng, 3-15 parts of radix glycyrrhizae, 0.15-1 part ofmagnesium stearate, 20-50 parts of starch and 30-40 parts of dextrin. The gastric ulcer composition is easy to prepare and has a remarkable effect on effective treatment of diseases such as acute andchronic body surface ulcer (diabetes ulcer), hemorrhoids, fistula sinus, rapid repair of damage to the digestive tract mucosa due to insertion of a catheter after surgery, esophageal ulcer, radiationesophagitis, ulcerative colitis, radiation proctitis, diarrhea with mucosal damage and blood in the stool.

The invention provides a traditional Chinese medicine composition for treating radiation proctitis and a preparation method. The traditional Chinese medicine composition is quick in effect taking, good in effect and free of side effects and comprises an oral medicine and an enema medicine. The oral medicine comprises the following raw material medicines, by weight, astilbe chinensis, angelica sinensis, netmeg, codonopsis pilosula, white hyacinth beans, atractylodes macrocephala, betel nuts, honeysuckle, medlar, eclipta prostrate, liquorice, radix paeoniae alba, agrimonia pilosa ledeb, bergenia scopulosa, ginger, donkey-hide glue, pseudo-ginseng, cinnamons, corydalis yanhusuo, golden cypress, roots of kudzu vine, coptidis rhizome and scutellaria baicalensis. The enema medicine comprises the following raw material medicines, by weight, purslane, roots of Chinese pulsatilla, gallnuts, ash barks, pericarpium granati, dahurian patrinia herbs, sanguisorba officinalis, caulis akebiae, caraway and iris tectorum.

The invention belongs to the technical field of preparation of traditional Chinese medicine compositions, and relates to a composition mainly prepared from natural Chinese herbal medicine for treating acute radiation proctitis. The composition is mainly prepared from the root of kudzu vine, scutellaria baicalensis, sow thistle roots, licorice roots, betel nut, bitter gourds, pomegranate bark, bighead atractylodes rhizome, purslane, dendrobe, okra and fig fruits. All the raw materials are cleaned, dried and cut into blocky granules, the raw material granules are weighed according to the weight matching ratios, the granules are mixed and placed into a marmite, rice vinegar is added, the granules are fried with a slow fire to be slightly yellow, the temperature is decreased to room temperature, the granules are ground into powder, and the powder is placed into a hollow capsule and sealed for use. The composition is scientific and reasonable in formula, simple in preparation technology, convenient to take and obvious in effect, has no side effect and has the good treatment effect on acute radiation proctitis.

The invention relates to a traditional Chinese medicine extract for treating acute radiation proctitis. The traditional Chinese medicine extract is prepared from, by weight, 6-9 parts of bletilla rhizome extract, 6-10 parts of Rhizoma Atractylodis Macrocephalae extract, 4-6 parts of Anemone chinensis extract, 6-8 parts of white peony root extract, 3-5 parts of dahurian angelica root extract, 10-15 parts of white hyacinth bean extract, 6-10 parts of Changium smyrnioides extract and 4-6 parts of licorice root extract. The traditional Chinese medicine extract has the efficacy of clearing heat and detoxifying, invigorating spleen, nourishing yin and harmonizing the stomach, activating tissues, promoting the stomach and intestine functions and restoring radiation injuries, has the advantages of fast action, high treatment effect, and no toxic or side effects, and is effective to acute and chronic radiation proctitis.

The invention discloses an enema for the treatment of radiation proctitis, and the enema is composed of panax notoginseng, pear peels, the roots of kudzu vine, sanguisorba officinalis, chickweed, radix paeoniae alba, fructus mume, herba violae, melaleuca leucadendron, agrimonia pilosa ledeb, radix codonopsis, clitocybe gigantean, atractylodes macrocephala koidz, fructus gardeniae, rhizoma atractylodis, caulis spatholobi, dendrobium, malabar spinach, coriolus versicolor, rhizoma corydalis, and radix glycyrrhizae. The enema can be used for significantly easing the clinical symptoms such as mucosanguineous feces, diarrhea, abdominal pain, tenesmus, anal causalgia and bearing-down pains and the like, improving positive stool occult bloods, intestinal mucosal lesions and radiation damages, and improving the living quality of patients; and the enema is low in recurrence rate, reliable in curative effect, stable in function, and has no toxic and side effect, so that the enema is a relatively satisfactory medicament for the treatment of radiation proctitis.

The invention discloses a traditional Chinese medicine formula and enema method for treating acute radiation proctitis. The traditional Chinese medicine formula comprises an orally-taken formula and an enema formula; the enema method comprises the steps that retention enema is performed with 250 ml of a traditional Chinese medicine preparation in the enema formula, enema liquid is contained in a 250-ml saline bottle in a sealing mode, a disposable infusion tube is inserted into the saline bottle, and the tail end of the infusion tube is connected with a disposable anal tube; a patient is told that excrement is emptied, a left lateral position is adopted, gas in the tubes is exhausted firstly, the anal tube coated with liquid paraffin oil is inserted into the anus by 12-15 cm and fixed with adhesive tape, and a regulator is switched on to regulate the dripping speed to be 75 drips per minute; after the medicine is infused into the intestinal tract, a knee-chest position is kept for 20-30 minutes, the left lateral position and a right lateral position are each kept for 30-40 minutes, a horizontal position is kept for 30-40 minutes, one preparation is used in one day, and seven days serve as a treatment course.

The invention relates to the field of traditional Chinese medicine formulas, in particular to traditional Chinese medicine decoction for treating radiation proctitis. The decoction is characterized by being prepared from, by weight, 12-20% of scutellaria baicalensis, 4-8% of coptis chinensis, 12-16% of semen coicis, 2-4% of atractylodes macrocephala koidz, 6-8% of poria cocos, 3-6% of hyacinth beans, 6-8% of fructus amomi, 6-8% of kudzu vine roots, 3-5% of costustoot, 5-7% of radix paeoniae alba, 3-5% of codonopsis pilosula, 3-7% of fructus psoraleae, 2-4% of nutmeg, 3-6% of betel nuts, 6-8% of fructus aurantii, 3-5% of red halloysite, 2-4% of sanguisorba officinalis and 3-4% of honey-fried licorice roots. The crude medicine materials are soaked in water, decocted and subjected to residue removal to obtain filter liquor. Material cost is low, compliance is high, and no side effect exists. The decoction can clear heat and dry dampness, purge fire for removing toxin, strengthen spleen and stop diarrhea, manage Qi and activate blood, achieve detumescence and promote granulation, and cool blood for hemostasis.

The invention discloses medicine composition for treating radiation proctitis after radiation therapy for treating cervical cancer. The liquid medicine is prepared from raw traditional Chinese medicine materials in parts by weight as follows: 7-15 parts of roots of fructus schisandrae sphenantherae, 11-20 parts of silene adenantha Franch., 10-25 parts of flos sophorae, 6-10 parts of galanga galangal seeds, 22-40 parts of chestnut pericarp, 6-10 parts of fineleaf schizonepeta herb, 9-20 parts of humifuse euphorbia herb, 6-20 parts of Chinese honeylocust spine and 11-20 parts of poederia scandens. The medicine composition for treating chronic radiation proctitis through enema has a definite curative effect and is safe and reliable.

The invention belongs to the technical field of medicines and in particular relates to a pharmaceutical composition for treating radiation proctitis. The problem in the prior art that an ideal medicine for the radiation proctitis does not exist is solved. The pharmaceutical composition takes a compound comprising the following formula as an effective pharmaceutical ingredient, wherein the structural formula is as shown in the description. In the formula, R1 is independently selected from H, alkyl or halogens; and R2 is independently selected from H, alkyl or -OH. The pharmaceutical compositionfor treating radiation proctitis disclosed by the invention can achieve effects of obviously relieving clinical symptoms such as mucous bloody stool, diarrhea, abdominal pain, anal burning pain and bearing-down pain and the like, improving positive fecal occult blood, colonoscopy mucosa lesions and radiation damage and improving the living quality of patients, is low in recurrence rate, reliablein curative effects, stable in effects and zero in toxic or side effect, and is a satisfactory drug for treating the radiation proctitis.

The invention belongs to the technical field of radiation medicine, and particularly relates to a method for establishing a rat delayed radiation proctitis model. According to the method, the optimalirradiation dose and the optimal irradiation mode for the successful establishment of the rat radiation proctitis model are screened out, and the rat model for the delayed radiation proctitis is established. The research result shows that 15 weeks after single local irradiation of 15.0Gy gamma rays, the rat rectum mucosa has inflammatory cell infiltration, fiber tissue hyperplasia also appears, and the secretion amount of inflammatory cytokines IL-2 and IL-6 of the rectum tissue is remarkably increased, which indicates the successful establishment of the radiation proctitis model. According tothe technical scheme provided by the invention, by establishing the rat delayed radiation proctitis model, an experimental basis is provided for the intensive study on the treatment means of the delayed radiation proctitis.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating radiation proctitis and a preparation method thereof.The traditional Chinese medicine composition is prepared from rhizoma coptidis processed with wine, radix scutellariae slices, radix rehmanniae recen, baked ginger, rhizoma atractylodis macrocephalae fried with bran, carbonized sanguisorba root, the root of Chinese pulsatilla, rhizoma bletillae, the root of kudzu vine, astragalus membranaceus, carbonized hair, honey-fried licorice root, radix paeoniae alba and rhizoma nelumbinis charcoal. According to the principle of clearing heat, promoting diuresis, detoxifying, cooling blood, dispersing blood stasis and stopping bleeding in traditional Chinese medicine, the pathological states of internal exuberance of fire-heat toxins and burns intestinal collaterals are comprehensively conditioned. Clinical research proves that the medicine can improve the traditional Chinese medicine syndrome score of patients suffering from stomachache, diarrhea, mucous bloody stool type rectum mucosa edema, hyperemia, bleeding and even ulceration and ulceration caused by radiotherapy, has practical popularization and application value, and is worthy of popularization and application. Therefore, the problems that the existing western medicine for treating radiation proctitis can only temporarily relieve symptoms, cannot repair intestinal mucosa injury and is easy to cause drug resistance and intestinal flora imbalance are solved.

The invention discloses a radiation proctitis causal prediction method and system fused with multi-modal information. The method comprises the following steps: acquiring and preprocessing multi-modal medical data of a patient; multi-modal high-dimensional joint features are extracted through a deep network; a depth generation decoupling model is constructed, and the joint features are decoupled into independent intrinsic pathogenic mechanism characterization and exogenous hybrid interference characterization; and based on a causal inference theory, blocking the influence of the hybrid characterization on prediction by applying intervention, and calculating a radiation proctitis causal prediction value only by using the intrinsic pathogenic mechanism characterization. According to the method, through causal characterization decoupling and causal intervention prediction, hybrid bias caused by heterogeneous data is effectively eliminated, shortcut learning of the model is avoided, and the generalization ability, robustness and technical reliability of the model in complex clinical environments such as cross-center and multi-device environments are improved.

The invention discloses a traditional Chinese medicine formula for radiation proctitis treating and nursing, belonging to the field of traditional Chinese medicine. The formula comprises the following bulk drugs of effective composition of herbs in parts by weight: 72 to 99 parts of garden burnet, 71 to 97 parts of rhizoma smilacis glabrae, 69 to 94 parts of Ledebouriella seseloides Wolff, 64 to 89 parts of Mangnolia officinalis, 63 to 86 parts of fructus aurantii, 60 to 83 parts of semen coicis, 55 to 80 parts of radices stellariae dichotomae, 53 to 77 parts of hairyvein agrimony, 48 to 75 parts of radix paeoniae alba, 47 to 72 parts of white atractylodes rhizome, 44 to 68 parts of dried tangerine or orange peel, 39 to 64 parts of golden cypress, 39 to 63 parts of sophora flower, 36 to 60 parts of dutchmanspipe root, 33 to 55 parts of angelica sinensis, 28 to 52 parts of rhizoma sparganii, 27 to 52 parts of safflower carthamus, 22 to 48 parts of fructus amomi and 20 to 46 parts of liquorice. A great amount of clinical verifications prove that the traditional Chinese medicine formula has the good effects of clearing away heat and toxic materials, invigorating spleen to remove dampness, removing stasis and dredging collaterals, and inducing astringency and can be widely used for treating acute and chronic radiation proctitis patients.

The invention discloses medicine composition for treating radiation proctitis after radiation therapy for treating cervical cancer. The liquid medicine is prepared from raw traditional Chinese medicine materials in parts by weight as follows: 7-15 parts of roots of fructus schisandrae sphenantherae, 11-20 parts of silene adenantha Franch., 10-25 parts of flos sophorae, 6-10 parts of galanga galangal seeds, 22-40 parts of chestnut pericarp, 6-10 parts of fineleaf schizonepeta herb, 9-20 parts of humifuse euphorbia herb, 6-20 parts of Chinese honeylocust spine and 11-20 parts of poederia scandens. The medicine composition for treating chronic radiation proctitis through enema has a definite curative effect and is safe and reliable.