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Chinese medicinal composition for treating radiation proctitis

A technology of radiation proctitis and composition, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as poor effect, combined rectocervical fistula or rectovaginal fistula, and blood in the stool

Inactive Publication Date: 2012-09-12
肖玉芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the acute stage, symptoms such as abdominal distension, diarrhea, and blood in the stool can be seen in 1 to 2 weeks after radiotherapy. In the late stage, blood in the stool may occur after 6 months to several years of radiotherapy, and even combined rectocervical fistula or rectovaginal fistula. cause great pain and inconvenience
At present, hormones and symptomatic therapy are basically used in China to relieve symptoms, but the effect is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Embodiment 1: a kind of traditional Chinese medicine composition for treating radiation proctitis, it is characterized in that taking raw material drug by following proportioning: Phellodendron 4~6g, Atractylodes atractylodis 2~4g, Rehmannia glutinosa 6~8g, Dendrobium 4~6g, Ophiopogon japonicus 2~4g, Codonopsis 6~8g, Yam 6~8g, Poria cocos 4~6g, Caulis Spatholobus 4~6g, Angelica 4~6g, Panax notoginseng 2~4g, Agrimony 4~6g, Radix Paeoniae Rubra 4~6g, Galla chinensis 2~4g, Amomum 4~6g, Chishizhi 4~6g, Myrobalan 4~6g, Licorice 4~6g.

Embodiment 2

[0010] Embodiment 2: a kind of Chinese medicine composition for the treatment of radiation proctitis is characterized in that the raw materials are weighed according to the following proportions: Phellodendron 6g, Atractylodes 2g, Rehmannia glutinosa 6g, Dendrobium 4g, Ophiopogon japonicus 4g, Codonopsis 6g, Chinese yam 6g, Poria 4g, Caulis Spatholobus 4g, Angelica 4g, Panax notoginseng 2g, Agrimony 4g, Radix Paeoniae Rubra 4g, Galla gall 2g, Amomum 4g, Chishizhi 4g, Myrobalan 4g, Licorice 4g.

[0011] Summary of clinical efficacy

[0012] 1. General information: 72 patients with radiation proctitis were selected for radiotherapy, aged 38-73 years old, with an average of 60.1 years old, and the course of disease was within 2 months, with an average of 6-15 days.

[0013] 2. Diagnostic criteria: history of abdominal radiation therapy, clinical manifestations: stool with pus, mucus, and exfoliated necrotic tissue, rectal examination: intestinal wall congestion, swelling in reddi...

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PUM

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Abstract

The invention relates to a Chinese medicinal composition for treating radiation proctitis. The composition is characterized by consisting of the following medicaments: 4 to 6 grams of phellodendron, 2 to 4 grams of atractylodes rhizome, 6 to 8 grams of dried rehmannia root, 4 to 6 grams of dendrobe, 2 to 4 grams of dwarf lilyturf root, 6 to 8 grams of pilose asiabell root, 6 to 8 grams of Chinese yam, 4 to 6 grams of tuckahoe, 4 to 6 grams of suberect spatholobus stem, 4 to 6 grams of Chinese angelica, 2 to 4 grams of pseudo-ginseng, 4 to 6 grams of agrimony, 4 to 6 grams of red peony root, 2 to 4 grams of gallnut, 4 to 6 grams of fructus amomi, 4 to 6 grams of red halloysite, 4 to 6 grams of myrobalan and 4 to 6 grams of liquorice. The composition has the advantages of clearing heat and detoxifying, strengthening spleen and eliminating dampness, removing stasis and dredging collaterals, inducing astringency and arresting discharge. Diseases are dialectically treated according to different symptoms in clinic. The Chinese medicinal composition is suitable for treating acute and chronic radiation proctitis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating radiation proctitis. Background technique [0002] As we all know, radiation therapy is one of the main methods to treat malignant tumors, and it is the main complication of radiotherapy for gynecological malignant tumors and male prostate malignancies. The pathogenesis is mainly that the proliferation of intestinal epithelial cells is inhibited by radiation, and the arterioles of the intestinal submucosal are damaged, causing obliterative endarteritis and venous endarteritis, and intestinal mucosal erosion, ulceration or bleeding may occur. In the acute stage, symptoms such as abdominal distension, diarrhea, and blood in the stool can be seen in 1 to 2 weeks after radiotherapy. In the late stage, blood in the stool may occur after 6 months to several years of radiotherapy, and even combined rectocervical fistula or rectovaginal fistula. causing great pain and inconvenien...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/00A61K35/64A61K33/26
Inventor 肖玉芹王天松
Owner 肖玉芹
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