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39 results about "Endarteritis" patented technology

Inflammation of the arterial intima.

Cefathiamidine monocrystal

The invention relates to cefathiamidine monocrystal, a preparation method, use and a composition thereof. The cefathiamidine monocrystal disclosed by the invention is prepared by comprising the following steps of: adding three solvents, namely ethanol, water and acetone, into a clean conical flask in any sequence according to any proportion, wherein the volume ratio of ethanol, water to acetone is (4-10):1:(0.05-3.67), during, before or after adding various solvents, adding cefathiamidine, dissolving at room temperature, and preparing cefathiamidine solution with the concentration of 0.05-0.5 g / ml; sealing by using a plastic film, and pricking a plurality of small holes on the plastic film; storing at 0-15 DEG C; and beginning to generate tiny crystals after about 48 h, and then obtaining cefathiamidine monocrystal after above 96 h. The preparation method disclosed by the invention is simple and convenient for operation and simple in equipment; the prepared monocrystal is good in stability; the cefathiamidine monocrystal composition disclosed by the invention is a composition composed of monocrystal and pharmaceutically acceptable carriers, preferably injection; the cefathiamidine monocrystal disclosed by the invention can be used for preparing medicines for treating respiratory tract infection, biliary tract infection, urinary tract infection, wound and surgical infection, skin and soft tissue infection, gynaecological infection, ear-nose-throat infection, endocarditis, blood poisoning, pneumonia and meningitis.
Owner:GUANGZHOU BAIYUNSHAN PHARM CO LTD

Chinese herbal medicine preparation for curing endometrial disease, infertility and habitual abortion

The invention relates to a Chinese herbal medicine preparation for curing the endometrial disease, the infertility and the habitual abortion. The Chinese herbal medicine preparation is prepared through decocting the following Chinese herbal medicines with water: angelica sinensis, astragalus membranaceus, rubus idaeus, ciliatenerve knotweed root, spiranthes sinensis ames, polygonum perfoliatum, kalimeris indica root, herba lycopi, achyranthes aspera, ginseng, rubus pluribracteatus, rubus parvifolius root, rhizoma polygonat, solanum lyratum, cyperus rotundus, cistanche, daughters red, crneate lespedeza, Chinese rose, galium aparine, achyranthes root, sagina subulata, gold rattan, crowndaisy chrysanthemum, herba leonuri, sargentgloryvine stem, semen cuscutae, semen euryales and the like. The Chinese herbal medicine preparation is beneficial for the recovery of the physical function and the organ function, has no any toxic or side effects, achieves more than 93% of effective rate in treating the female infertility and the habitual abortion, achieves more than 94% of effective rate in treating the endometritis and the pelvic inflammation, achieves more than 89.4% of effective rate in treating the cervical hypertrophy, the cervical erosion, the xeromenia, the inflammatory mass, the uterine fibroid, the ovarian cyst and other gynecological diseases, and achieves more than 94.1% of effective rate in treating sterility due to oligozoospermia and the necrospermia.
Owner:屈力军

Preparation method of ornidazole gastric floating tablets and use thereof

The invention discloses a preparation method and applications of gastric floating tablets containing ornidazole, belonging to a novel technical field of medicament and relating to a novel medicament form of ornidazole. 1. The gastric floating tablets are used to treat a plurality of diseases caused by bacteroides fragilis, bacteroides distasonis, bacteroides oval window, etc.; (2) oral cavity infections: pericoronitis, periapical periodontitis, pericoronitis, acute ulcerouse gingivitis etc.; (3) gynae infections: endometritis, myometritis, oviduct or ovarian abscess, pelvic cavity soft tissue infection, haemophilis vaginitis etc.; (4) surgical infections: wound infection, abscess of epidermis, bedsore ulcerouse infection, cellulites, gas gangrene etc.; (5) brain infections: meningitis, brain abscess; (6) septicaemia and severe general infections etc. 2. The gastric floating tablets are used to prevent infections before an operation and treat anaerobic infections after an operation. 3. The gastric floating tablets are used to treat urogenital canal trichomonas and giardia lamblia infections, such as trichomoniasis etc. 4. The gastric floating tablets are used to treat alimentary system amebiasis, such as amebic dysentery, amoebic liver abscess etc. The new medicament form is characterized in that the surface thereof is hydrated into gel after contacting with gastric juice at body temperature so as to cause volume expansion because the gastric floating tablets contain a plurality of hydrophilic macromolecule materials. Weight of the tablets is less than floating force of the gastric juice, so the tablets float on the gastric juice so as to prolong time in a stomach.
Owner:BEIJING HOPE HUGE PHARM SCI

A kind of perfusion agent for treating dairy cow endometritis and preparation method thereof

The invention relates to a perfusion agent for treating cow endometritis, and further relates to a preparation method for the perfusion agent. Components of each 100 L of the perfusion agent comprise: 5-10 kg of povidone iodine; 5-10 kg of borneol; 0.1-0.5 kg of a suspending agent, the balance of polyethylene glycol-400. The perfusion agent is prepared through the following method: (1) respectively weighing the povidone iodine, the borneol and the suspending agent, then uniformly mixing to obtain a mixture I for later use; (2) adding 40-60 L of the polyethylene glycol-400 to the mixture I while stirring; after uniformly stirring, placing the resulting mixture containing the polyethylene glycol-400 in a grinder to carry out grinding for twice until the drug emulsion fineness is 200 mum to obtain a mixture II; (3) further adding the polyethylene glycol-400 to the mixture II until the total volume is 100 L, uniformly stirring and packing. According to the present invention, the perfusionagent adopts the combination method of the traditional Chinese drug and the western medicine, provides a significant therapeutic effect for the cow endometritis; and the drug resistance is difficult to be generated and the perfusion agent is easy to be used.
Owner:ZHENGZHOU BARY ANIMAL PHARMA

Preparation and method of biosensor for detecting concentration of hot calcium in milk produced by dairy cow

The invention discloses a preparation method of a biosensor for detecting the concentration of hot calcium in milk produced by a dairy cow. The preparation method comprises the following steps: carboxylation of a single-walled carbon nanotube (SWNT): placing the single-walled carbon nanotube in a mixed solution of concentrated nitric acid and concentrated sulfuric acid in a volume ratio of 1: 3 for 6 hours; washing the SWNT with enough Milli-Q purified water until the pH value of the water is neutral; putting the treated SWNT into a vacuum furnace, and heating for 60 minutes at the temperature of 80 DEG C; dissolving 1 mg of SWNT and performing ultrasonic treatment to uniformly disperse into 2 mL of a dimethylformamide solution. The biosensor disclosed by the invention has the advantages that by using the biosensor disclosed by the invention, the milk cow blood calcium content can be effectively detected, and compared with the existing milk cow blood calcium detection method, the biosensor disclosed by the invention has the advantages of high precision and high detection speed, provides powerful data reference for monitoring diseases such as milk cow rumen air blowing, abomasal displacement, endometritis and mastitis caused in production. The blood calcium content of the dairy cow can be effectively monitored for a long time by using the biosensor.
Owner:INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI

Screening method, cell model and application of anti-cow endometritis drug

The invention provides a method for in vitro screening and detection of anti-cow endometritis drugs, which is to induce an inflammatory reaction in cow endometrial epithelial cells cultured in vitro, and then add the drug to be tested, and detect the inflammatory protein in the cells relative to the internal reference Changes in protein expression accurately reflect the anti-inflammatory activity of the drug to be tested: if the relative expression of the inflammatory protein decreases, the drug to be tested has anti-inflammatory activity, and the relative decrease in expression is the relative anti-inflammatory activity of the drug to be tested; otherwise Then there is no anti-inflammatory activity; wherein, the inflammatory protein is an integrin-linked kinase. The method for screening and detecting the anti-cow endometritis drug in vitro of the present invention can realize simple and rapid screening and detection of the anti-cow endometritis activity of the drug to be tested in vitro. When multi-well plates are used, high-throughput screening and detection can be achieved, and the screening and detection results have important reference value for the modern clinical application and modern development of traditional Chinese medicine.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Method for screening anti-endometritis drugs in dairy cows, cell model and application

The invention provides a method for in vitro screening and detecting anti-endometritis drugs in dairy cows. The method for in vitro screening and detecting the anti-endometritis drugs in the dairy cows comprises the steps that after in vitro cultured dairy cow endometrial epithelial cells are induced to have an inflammatory reaction, drugs to be detected are added, and the anti-inflammatory activity of the drugs to be detected is accurately reflected by detecting the expression change of inflammatory proteins in cells relative to internal reference proteins; if the relative expression quantityof the inflammatory proteins is reduced, the drugs to be detected has anti-inflammatory activity, and the multiple of the relative expression quantity is the magnitude of the relative anti-inflammatory activity of the drugs to be detected; otherwise, the anti-inflammatory activity does not exist; and the inflammatory proteins are integrin linked-kinase. According to the method for in vitro screening and detecting the anti-endometritis drugs in the dairy cows, the anti-endometritis activity in the dairy cows of the drugs to be detected can be simply, conveniently and rapidly screened and detected in vitro. When a multi-hole board is used, high throughput screening and detection can be realized, and a screening and detection result has important reference value for modern clinic applicationand modernization development of traditional Chinese medicines.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS

Chinese herbal medicine preparation for curing endometrial disease, infertility and habitual abortion

The invention relates to a Chinese herbal medicine preparation for curing the endometrial disease, the infertility and the habitual abortion. The Chinese herbal medicine preparation is prepared through decocting the following Chinese herbal medicines with water: angelica sinensis, astragalus membranaceus, rubus idaeus, ciliatenerve knotweed root, spiranthes sinensis ames, polygonum perfoliatum, kalimeris indica root, herba lycopi, achyranthes aspera, ginseng, rubus pluribracteatus, rubus parvifolius root, rhizoma polygonat, solanum lyratum, cyperus rotundus, cistanche, daughters red, crneate lespedeza, Chinese rose, galium aparine, achyranthes root, sagina subulata, gold rattan, crowndaisy chrysanthemum, herba leonuri, sargentgloryvine stem, semen cuscutae, semen euryales and the like. The Chinese herbal medicine preparation is beneficial for the recovery of the physical function and the organ function, has no any toxic or side effects, achieves more than 93% of effective rate in treating the female infertility and the habitual abortion, achieves more than 94% of effective rate in treating the endometritis and the pelvic inflammation, achieves more than 89.4% of effective rate in treating the cervical hypertrophy, the cervical erosion, the xeromenia, the inflammatory mass, the uterine fibroid, the ovarian cyst and other gynecological diseases, and achieves more than 94.1% of effective rate in treating sterility due to oligozoospermia and the necrospermia.
Owner:屈力军

Traditional Chinese medicine composition for preventing sheep endometritis as well as preparation method and application thereof

The invention belongs to the technical field of traditional Chinese medicines in the breeding industry, and discloses a traditional Chinese medicine composition for preventing sheep endometritis as well as a preparation method and application thereof. The traditional Chinese medicine composition for preventing sheep endometritis is prepared from the following raw material in parts by weight: 14-17parts of philippine flemingia root, 9-12 parts of cherokee rose root, 9-12 parts of motherwort, 9-12 parts of Chinese angelica, 7-10 parts of szechuan lovage rhizome, 9-12 parts of heartleaf houttuynia herb, 7-10 parts of coptis, 3-6 parts of astragalus and 3-6 parts of liquorice. According to the traditional Chinese medicine composition for treating sheep endometritis and the preparation methodthereof, related experiments show that the traditional Chinese medicine composition has the functions of clearing away heat and drying dampness, activating blood circulation to dissipate blood stasisand warming kidney to strengthen primordial qi and can effectively relieve inflammatory reaction, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The composition can be used for preventing sheep endometritis caused by escherichia coli infection.
Owner:GANSU AGRI UNIV

Traditional Chinese medicine composition for treating endometritis and preparation method thereof

The invention relates to a traditional Chinese medicine composition for treating endometritis and a preparation method thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 7.69 parts of picriafel-terrae lour, 11.54 parts of elephantopus scaber, 7.69 parts of radix angelicae sinensis, 11.54 parts of millettia dielsiana, 11.54 parts of zanthoxylum nitidum, 11.54 parts of membranaceous beautyleaf root, 11.54 parts of persimmon leaves, 11.54 parts of herba thlaspis and 15.38 parts of ficus simplicissima lour. The method for preparing the traditional Chinese medicine composition comprises the following steps: carrying out alcohol extraction on the picriafel-terrae lour, the elephantopus scaber, the herba thlaspis and the ficus simplicissima lour, and carrying out aqueous extraction on the herb residue after the alcohol extraction and the rest five components. The effect of the traditional Chinese medicine composition provided by the invention is verified by a manner of putting foreign bodies in uterine to prepare a rat endometritis model. The traditional Chinese medicine composition provided by the invention has the effect on treating gynecologic inflammation, in particular on treating endometritis; and the effect is better than the prior art.
Owner:GUANGXI WUZHOU PHARMA GRP

Preparation method of traditional Chinese medicine microecological preparation for preventing and treating dairy cow endometritis

A method for preparing a traditional Chinese medicine microecological preparation for preventing and treating dairy cow endometritis, which is prepared according to the following method: superfinely pulverize motherwort, safflower, peach kernel, honeysuckle, pulsatilla, echinacea, gynostemma, astragalus, and licorice, add water to a boil, Keep warm on low heat, cool and filter, collect the filtrate, add sugar to boil, cool down to room temperature, inoculate the probiotics fermented by Lactobacillus, Kombucha and yeast, and give the probiotics to cows in proportion. The traditional Chinese medicine microecological preparation of the present invention has the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, sterilizing and reducing inflammation, etc., is rich in active substances of Chinese herbal medicine, active small peptides, lactic acid and probiotics, has good therapeutic effect, and replaces traditional antibiotic treatment methods. The preparation method of the present invention is simple, easy to use, free of drug residue, free of any toxic and side effects, high in live drug content, suitable for industrial production, and has a good market prospect, and also has a good effect on endometritis infertility in dairy cows. treatment effect.
Owner:石家庄博瑞正诚饲料有限公司
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