65 results about "Mucosal lesions" patented technology

An oral care composition and method of using are provided for treating and preventing malodors or disease conditions of the oral cavity in warm-blooded animals, including humans. When applying an oral care effective amount of the oral care composition of the present invention to the mucosal tissue of the oral cavity, the gingival tissues of the oral cavity, and/or surface of the teeth. The application can be as a liquid for bathing, rinsing or gargling, or lather generated by brushing the teeth for a sufficient time. After rinsing, gargling or brushing, the composition of the present invention should be swallowed to achieve effective reduction of various organisms, diseases and malodors. An oral care effective amount can also prevent and heal mouth sores and canker sores.

Serum compositions for application to endothelial tissue are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be used to treat conditions of the mouth such as dry mouth and mouth sores.

A device and method for the treatment of mouth sores or ulcers, such as canker sores. The device includes a vacuum bulb connected to a treatment tip via a fluid-tight conduit. The device allows for a vacuum to be applied to the area of a canker sore by positioning of the tip and actuation of the vacuum bulb. Through gentle application of a vacuum to the area afflicted with a canker sore, the sensitivity of the afflicted area is diminished and the healing process is significantly improved. The device preferably includes disposable applicator tips.

The invention relates to a method for analyzing molecular typing based on gastric mucosal lesion proteomics, different gastric mucosal lesion proteomics molecular subtype characteristics and correlation between the molecular typing and the subtype characteristics and the gastric mucosal lesion progress. A protein marker database related to gastric cancer and gastric mucosal lesion progress is established by calculating the relationship between protein expression and gastric mucosal tissue pathological state, proteome molecular subtype and gastric mucosal lesion progress, and a gastric mucosallesion sample disease progression risk scoring system is established. According to the invention, a molecular epidemiological research means is combined with bioinformatics analysis and machine learning, microscopic and macroscopic gastric cancer cause risk factors are integrated, a gastric mucosal lesion molecular typing framework and a progress risk prediction model are established, and a foundation is laid for finally constructing a comprehensive and systematic gastric cancer prevention strategy.

The invention discloses lactobacillus fermentum capable of regulating intestinal tract Claudin-1 and application of the lactobacillus fermentum, and belongs to the technical field of microorganisms. According to the lactobacillus fermentum CCFM1058 provided by the invention, the barrier function of intestinal mucosa can be effectively improved; compared with a colitis group, the lactobacillus fermentum CCFM1058 has the advantages that the expression level of the Claudin-1 protein gene is increased by nearly two times, and the colonic mucosal lesion is repaired. The level of lactobacillus fermentum CCFM1058 for improving the Claudin-1 is obviously better than that of a lactobacillus fermentum strain CECT5716 of a model strain. Therefore, the lactobacillus fermentum CCFM1058 with the function of regulating the Claudin-1 to protect the intestinal mucosa barrier has a wide application prospect in the fields of foods and microecological preparations.

The present invention provides a Chinese medicine compound for curing gastric and duodenal ulcer, made from the raw materials with weight portions such as yanhusuo, dandelion, nutgrass flastedge, mastic gum, alum and liquorice, and a preparation method of capsule, tablet, pill, granule, powder, dropping pill and oral liquid of the compound. The present invention has the functions of obvious sterilization and bacteriostasis on helicobacter pylori, reduction of gastric juice amount, gastric free acid and total acidity, and pepsin output, as well as pain alleviating and inflammation resisting, so the present invention has the functions of inhibiting stress type, ostium pyloricum deligation, acetic acid and ethanol ulcer, as well as pain alleviating and inflammation resisting. In addition, the present invention can reduce the stimulus factors of chronic gastricism, gastric ulcer and gastratrophia lesions, improve the symptoms of patients with gastric ulcer and play a promoting role in repairing and improving gastric mucosal lesion.

The invention provides a special medical purpose formula food compound with a digestive tract immunoregulation function and a preparation method thereof, and belongs to the field of special food. Thespecial medical purpose formula food compound is prepared from L-glutamine, oligopeptide, protein peptide, probiotics and stachyose. The preparation method of the compound comprises the following steps of crushing, screening, premixing, blending, inert gas filling, sub-packaging and packaging. The compound and food or special food or a pharmaceutically acceptable carrier or accessory can be made into an oral preparation. The preparation can be powder or tablets or capsules or granules or oral liquid. The compound can be applied for preparing food or special food or medicines which have a protection effect on gastric mucosal lesions and can adjust intestinal flora.

The invention discloses bunge cherry seed Chinese medicinal decoction for treating constipation. The Chinese medicinal decoction is prepared from the following Chinese herbal medicines in part by weight: 180 to 300 parts of bunge cherry seed, 180 to 300 parts of fructus cannabis, 140 to 220 parts of cassia seed, 140 to 220 parts of vietnamese sophora root and 140 to 220 parts of coix seed; the Chinese herbal medicines have the effects of clearing heat and lubricating bowels; the Chinese medicinal decoction has a good therapeutic effect on sthenia constipation and an obvious curative effect of relieving dry stool, abdominal swelling, flushed face and general fever, vexation and dry mouth or mouth sores and scanty dark urine; and the Chinese medicinal decoction has the advantages of no toxic or side effect and obvious effect, and pain of patients is radically relieved.

The invention relates to a composition for treating a gastric ulcer combined gastrointestinal bleeding. The composition comprises the following active components in parts by weight: 8-25 parts of ginsenoside Re, 10-30 parts of ginsenoside Rg3 and 5-20 parts of ginsenoside Rh1. The composition has the effects of obviously improving the gastric mucosal lesion and gastric mucosal lesion, promoting the blood coagulation and stopping bleeding, and is capable of effectively treating and/or preventing gastrointestinal diseases of the gastric ulcer combined gastrointestinal bleeding and the like.

The invention discloses a preparation method of a chenopodium quinoa willd extract and application of the chenopodium quinoa willd extract in preparation of medicines and foods for preventing gastric mucosal injury. Experiments prove that the chenopodium quinoa willd extract has the effect of repairing gastric mucosal lesion, and the curative effect is exact.

The present invention relates to methods for improving the detection of pathologies in the colon and method of flagging the mucosal lesions in the colon.

The present invention relates to the use of the nutrition supplement known as vitamin B12 (cobalamin) to treat or prevent mucosal lesions. It relates particularly to treatment of mucosal lesions and prevention of development of recurrent mucosal lesions by the repeated administration over a period of time of vitamin B12 where a subject has normal, or above normal, serum vitamin B12 levels. Compositions (medicaments), including friendly carriers (e.g. chewing gum), and kits, for vitamin B12 delivery to mucosal lesions or other injuries are also provided.

The invention provides a composition with a gastric mucosal lesion protection effect, which is prepared from the following components in parts by weight: 50 to 70 parts of hericium erinaceus extract, 40 to 60 parts of morchella esculenta extract, 30 to 50 parts of rhizoma bletillae extract, 20 to 40 parts of fingered citron extract, 260 to 340 parts of sea buckthron oil and 10 to 30 parts of beewax. Compared with the prior art, according to the theory of traditional Chinese medicine, aiming at the pathogenesis of insufficiency of qi in spleen and stomach and unsmooth qi and blood, the hericium erinaceus extract, the morchella extract, the rhizoma bletillae extract and the fingered citron extract creatively form the traditional Chinese medicine composition, and the hericium erinaceus extract in the formula strengthens the spleen and stomach, is particularly suitable for spleen and stomach meridians and serves as a monarch drug. Toadstool harmonizes stomach, promotes digestion, reduces phlegm and regulates qi; the rhizoma bletillae has the effects of inducing astringency, promoting tissue regeneration, eliminating stagnation and removing stasis, promoting digestion, relieving stasis, promoting tissue regeneration, eliminating rotting, regulating qi and removing stasis, and is used as a ministerial drug together, so that the bleeding volume of gastric mucosa is increased, oxygen supply is promoted, the resistance is enhanced, the blood circulation of the gastric mucosa is smooth, and the qi and blood of a body are smooth. The fingered citron is an adjuvant drug, has the effects of promoting the circulation of qi, tonifying the liver, warming the stomach, tonifying the spleen, arresting vomiting and the like, is soft in nature, does not lack strength, treats the liver and the spleen without hurting the body resistance, is flexible and appropriate in the formula, and plays good assistant and assistant roles.

The invention discloses a traditional Chinese medicine composition which is mainly prepared from the following traditional Chinese medicine monomers including puerarin, berberine, baicalein, glycyrrhizic acid and magnolol. Experimental results show that rat colitis treated by the traditional Chinese medicine composition is obviously relieved, the weight loss, bloody stool, diarrhea and disease activity index (DAI) score is reduced, the colon length is shortened, and the colon mucosal lesion index (CMDI) score and histological score are reduced, so that the traditional Chinese medicine composition disclosed by the invention has good effects of resisting ulcerative colitis and damp-heat syndrome diarrhea, and has a wide application prospect in the research aspect of related medicines. Besides, the problems of unclear components and unclear mechanisms of a traditional Chinese medicine compound in the past are solved through a traditional Chinese medicine monomer formula, the limitation toresearch and application is broken through, and a new thought and help are provided for subsequent research, development, optimization and innovation of traditional Chinese medicines.

The invention belongs to the field of medicines and daily chemicals, and particularly relates to a group of novel polypeptides and application thereof in preparation of medicines for treating/or preventing skin wounds or mucous membrane injury. The novel polypeptide provided by the invention can be combined with an epidermal growth factor receptor EGFR to play a biological effect, and can be used for preparing medicines or daily chemical products for treating/or preventing skin or mucous membrane diseases, acute and chronic gastrointestinal diseases, tumors and other related diseases.

The invention discloses Jinjusiqing tea, which is prepared from 7 to 10 parts of honeysuckle flowers, 5 to 8 parts of chrysanthemum flowers, 2 to 6 parts of herba menthae, 4 to 8 parts of herba taraxaci, 3 to 8 parts of flower of Chinese scholartree, 1 to 4 parts of stevia rebaudiana and 5 to 9 parts of Pu'er tea in parts by weight. The tea provided by the invention is prepared from honeysuckle flowers, chrysanthemum flowers, herba menthae, herba taraxaci, flower of Chinese scholartree, stevia rebaudiana and Pu'er tea through work procedures of enzyme deactivation, stir-frying drying, crushing, mixing, bag charging and the like. After people brew the ta by hot water and drink the tea, the effects of clearing away heat and toxic materials, reducing internal heat, relieving throat discomfortand nose and mouth sores, clearing away liver heat, improving eyesight, relieving constipation, treating hypertension, hyperlipidemia and hyperglycemia, beautifying the skin, keeping young, resistingbacteria, diminishing inflammation, resisting viruses, preventing flue and enhancing immunity can be achieved, so that the health care and health preservation effects of the tea are improved; the market competitiveness is improved.

The invention discloses a ureteral stent tube capable of relieving mucosal lesion. The stent tube is a hollow hose and comprises a tube body, bent sections and blunt thickening sections; the two endsof the tube body are provided with bent sections respectively. The annular diameter of the bent section is smaller, and the bent section is of a disc-shaped structure; the free end of each bent section is provided with a blunt thickening section, the outer diameter of each blunt thickening section is larger than that of each bent section; each blunt thickening section is of a spherical structure,and the end of each blunt thickening section is of a spherical structure, so that a series of side effects can be avoided; the tube body, the bent sections and the blunt thickening sections are identical in inner diameter, and the bent sections and the tube body are identical in outer diameter. According to the invention, tube pushing is not needed, the operation process is simplified, the steps are reduced in the implantation process, and the pain of a patient can be reduced; meanwhile, the two ends of the stent tube are arranged to be of a blunt structure, in the pushing-in process and afterthe stent tube is placed on the human body, stimulation to the renal pelvis and the bladder mucosa can be reduced at the ends, and the phenomena of hematuresis and the like caused by mucous membraneinjury and bleeding are avoided.

The present invention provides evidence of post-vaccination immunologic changes in target HPV induced cervical intraepithelial neoplasias that suggest the induction of clinically relevant tissue-localized immune responses, despite modest detectable responses in circulating T lymphocytes. The inventive methods allow for identification of immunological responses to HPV immunotherapies, and means for monitoring responses during clinical trials and treatment regimens.

The invention discloses a composition with an auxiliary protection function on gastric mucosal lesion and application of the composition, and belongs to the technical field of health care products. According to the composition disclosed by the invention, the hericium erinaceus extract, the broccoli seed extract, the turmeric extract and the radix aucklandiae extract are compounded and matched, so that compared with existing commercially available products or similar compositions, the composition disclosed by the invention has a remarkable synergistic gastric mucosal lesion protection effect; animal model experiments and human body trial feeding experiments prove the efficacy of the product. The product is mild and stable in property, does not obviously stimulate the stomach after being used, and can be effectively applied to preparation of medicinal and edible products. The invention also provides application of the composition in preparation of a product with an auxiliary protection function on gastric mucosal lesion.

The invention provides a health-preserving and health-care foot patch which comprises a non-woven packing bag and a powdered drug filled in the non-woven packing bag, wherein the powdered drug comprises bamboo vinegar powder and a mixed extract of folium artemisiae argyi, fructus evodiae, clove, cassia twigs and angelica dahurica; the mixed extract in each of the non-woven packing bags is preparedby crushing, high-pressure soaking, boiling, extracting, pre-forming, drying into a paste and powdering of 3-5 g of folium artemisiae argyi, 3-5 g of fructus evodiae, 3-5 g of clove, 3-5 g of cassiatwigs and 3-5 g of angelica dahurica. According to the invention, through performing high-pressure soaking on medicinal materials in mixed liquid of yellow wine and water, not only is the boiling timeeffectively shortened, but also the full extraction of active ingredients is facilitated; when in use, the health-preserving and health-care foot patch is attached to a Yongquan acu-point of a foot and is absorbed by foot skin, so that the peripheral circulation can be effectively promoted, the fatigue is improved, the pressure is relieved, and insomnia and dreamful sleep, mouth sores and other sub-health phenomena caused by pressure can be alleviated in an auxiliary manner; the health-preserving and health-care foot patch is simple to use and convenient to carry, and the preparation processis simple and easy to operate.

The present invention discloses a ziziphus jujuba multi-enzyme paclitaxel oral spray preparation method, which comprises: selecting 8-12 parts by weight of ziziphus jujuba compound enzyme, 0.01-0.02 part by weight of paclitaxel, 90-100 parts by weight of an aloe gel solution, and 0.8-1.2 parts by weight of peppermint essence as raw materials, pouring the four components into a high speed mixer, uniformly mixing, pumping into an ozone sterilization device through a micro beverage pump, carrying out a sterilization treatment, filling, and sealing. According to the present invention, the ziziphus jujuba multi-enzyme paclitaxel oral spray prepared through the method does not have toxic-side effects, and provides treatment effects on various symptoms caused by oral cancer, esophageal cancer, stomach cancer, mouth sores, periodontitis, ozostomia, pharyngitis, indigestion, gastric distention, gastric acid deficiency, and multi-enzyme deficiency.

The invention discloses an oral care solution for a tumor chemotherapy patient. The oral care solution comprises, by weight, 4-6 parts of octane, 7-8 parts of tea polyphenol, 1-4 parts of carboxybutylchitosan, 6-8 parts of cnidium, 2-3 parts of nervilia fordii, 1-2 parts of ascorbic acid, 1-2 parts of phenoxyethanol, 4-6 parts of a nitrofurazone solution and 20-30 parts of water. The oral care solution has an inhibitory effect on various microorganisms, has an anti-oxidation effect, can be used for treating mouth sores, can be used for treating infections and suppressing headache, has a sweettaste, is easy to accept, can effectively prevent oral malodor, oral ulcers and throats swelling and pain, and can significantly improve oral breath.