The invention discloses a medicine solution for enema for prevention of radiation rectal injury of cervical carcinoma patient. The medicine solution comprises the following active ingredients: pseudo-ginseng, pear peel, the root of kudzu vine, garden burnet, chickweed, white paeony root, smoked plum, herba violae, melaleuca leucadendron, hairyvein agrimony, codonopsis pilosula, clitocybe gigantean, white atractylodes rhizome, jasmine, rhizoma atractylodis, caulis spatholobi, dendrobe, basella alba, liquorice, trollflower, beautyberry leaf, mulberry, longan seed, puberulous glochidion branchlet and leaf and radix tinosporae, wherein the method for preparing the medicine solution comprises the steps of adding proper water in each active ingredient, boiling for two times with warm fire, condensing to 150-300 ml, and filtering through a gauze to obtain the medicine solution retention enema.