Composite probiotics capable of performing dual-way regulation on constipation

A compound probiotics, two-way regulation technology, applied in the direction of drug combination, medical preparations containing active ingredients, digestive system, etc., can solve the problems of low product performance, easy to lose activity, etc., to remove intestinal waste and ensure live bacteria Quantitative, rapid regulation of the effect of the intestinal microenvironment

Inactive Publication Date: 2019-04-02
吉林禾未来功能产品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since live bacteria are easy to lose activity during processing, transportation and storage, the marked value of many preparations on the market is far greater than the actual value, and the performance of the product itself is low

Method used

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  • Composite probiotics capable of performing dual-way regulation on constipation
  • Composite probiotics capable of performing dual-way regulation on constipation
  • Composite probiotics capable of performing dual-way regulation on constipation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 compound probiotics X1

[0024] Comprising the following components by mass percentage:

[0025] Lactobacillus acidophilus 18wt%; Lactobacillus reuteri 22wt%; Bifidobacterium lactis 18wt%; Bifidobacterium infantis 11wt%; Bifidobacterium longum 4wt%; 5 wt% of Lactobacillus lysosus; the remainder is xylooligosaccharides.

[0026] Detection process: According to national standards, the number of viable bacteria is detected by plate culture counting method. Choose to make 10 -6 and 10 -8 For the homogeneous sample solution of the dilution degree, draw 0.1mL of the homogeneous sample solution for each dilution degree and place it on 2 MRS agar plates, and use an L-shaped rod to coat the surface. Count all the colonies on the plate after anaerobic culture at 36°C±1°C for 48h±2h.

[0027] Test result: total number of live bacteria 1.2×10 9 CFU / g.

Embodiment 2

[0028] Embodiment 2 compound probiotics X2

[0029] Lactobacillus acidophilus 22wt%; Roy's lactobacillus 18wt%; Bifidobacterium lactis 20wt%; Bifidobacterium infantis 11wt%; Bifidobacterium longum 6wt%; 5 wt% of Lactobacillus lysosus; the remainder is xylooligosaccharides.

[0030] Detection process: According to national standards, the number of viable bacteria is detected by plate culture counting method. Choose to make 10 -6 and 10 -8 For the homogeneous sample solution of the dilution degree, draw 0.1mL of the homogeneous sample solution for each dilution degree and place it on 2 MRS agar plates, and use an L-shaped rod to coat the surface. Count all the colonies on the plate after anaerobic culture at 36°C±1°C for 48h±2h.

[0031] Test result: total number of live bacteria 1.0×10 9 CFU / g.

Embodiment 3

[0032] Embodiment 3 compound probiotics X3

[0033] Lactobacillus acidophilus 21wt%; Lactobacillus reuteri 18wt%; Bifidobacterium lactis 22wt%; Bifidobacterium infantis 10wt%; Bifidobacterium longum 5wt%; 5 wt% of Lactobacillus lysosus; the remainder is xylooligosaccharides.

[0034] Detection process: According to national standards, the number of viable bacteria is detected by plate culture counting method. Choose to make 10 -6 and 10 -8 For the homogeneous sample solution of the dilution degree, draw 0.1mL of the homogeneous sample solution for each dilution degree and place it on 2 MRS agar plates, and use an L-shaped rod to coat the surface. Count all the colonies on the plate after anaerobic culture at 36°C±1°C for 48h±2h.

[0035] Test result: total number of viable bacteria 1.4×10 9 CFU / g.

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Abstract

The invention relates to composite probiotics capable of performing dual-way regulation on constipation. The composite probiotics comprise the following components in percentage by mass of 18-22wt% oflactobacillus acidophilus, 18-22wt% of lactobacillus reuteri, 18-22wt% of bifidobacterium lactis, 8-11wt% of bifidobacterium infantis, 4-6wt% of bifidobacterium longum, 4-6wt% of bifidobacterium adolescentis, 4-5wt% of lactobacillus plantarum, 4-5wt% of lactobacillus rhamnosus and the balance of xylooligosaccharide. According to the composite probiotic products, the final viable count can achieve10<9>-10<10>CFU/g, the content of viable bacteria is high, and the dual-way regulating effect is notable.

Description

technical field [0001] The invention belongs to the technical field of microbial preparations, in particular to a compound probiotic capable of bidirectionally regulating constipation. Background technique [0002] The gut microbiome is critical to maintaining human health. The human body's vitamin synthesis, promotion of growth and development, material metabolism and immune defense function all play an important role. It is a necessary factor for maintaining human health and a mirror reflecting the stability of the internal environment of the body. [0003] The irrational use and abuse of antibiotics is one of the main causes of intestinal microecological disturbance. Due to unreasonable application, the pattern of mutual restriction between intestinal bacterial populations or communities is disturbed, and drug-resistant strains are produced at the same time, which multiply rapidly, causing the balance of intestinal microecology to be destroyed. The addition of compound ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61K35/745A61P1/10
CPCA61K35/745A61K35/747A61P1/10A61K2300/00
Inventor 王振东连鑫
Owner 吉林禾未来功能产品有限公司
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