14results about How to "Reduce diarrhea" patented technology

The invention belongs to the technical field of medicines, and provides application of Nintedanib and a plant-derived cyclic peptide and radix pseudostellariae cyclic peptide B combined medicine in preparation of a medicine for treating pulmonary fibrosis, the Nintedanib and the plant-derived cyclic peptide and radix pseudostellariae cyclic peptide B combined medicine can play a synergistic effect, and the inhibition effect on the pulmonary fibrosis process is remarkably improved. The toxic and side effects of diarrhea and intestinal mucosa injury caused by nintedanib are reduced, and a good choice is provided for clinical treatment of pulmonary fibrosis.

The invention provides a sow feed added with puffed rice and a preparation method of the sow feed. The sow feed comprises the following components in parts by weight: 30-50 parts of puffed rice, 10-20 parts of soybean meal, 10-20 parts of wheat bran, 2-6 parts of sugar / beet pulp polypeptide, 20-30 parts of mixed forage powder, 2-6 parts of pea fibers, 2-6 parts of pennisetum purpureum dietary fibers, 5-15 parts of manioc waste, 4-10 parts of a haematococcus extract, 2-8 parts of a cercis chinensis extract, 1-4 parts of a composite strain, 0.1-0.6 part of temperature-resistant phytase and 0.5-0.9 part of myristic acid. According to the present invention, the production method is simple, and the prepared sow feed can improve the lactation yield of sows, increase the number of immune globulins in milk, improve the immunity of piglets, improve the intestinal microbiological structure and the intestinal morphology of the piglets, reduce the diarrhea of the piglets, improve the immunity of the piglets, improve the immunity of the piglets, improve the immunity of the piglets, and improve the immunity of the piglets. The growth and development of piglets are promoted.

The invention relates to the field of feed raw materials, and discloses a feed plant enzymolysis protein with a strong food calling effect and a preparation method thereof, the preparation method comprises the following steps: S1, dispersing and reducing viscosity: reducing the viscosity of a protein powder raw material through shearing force generated by high-speed rotation of a dispersing disc; step S2, enzymolysis of polysaccharide substances: plant protein powder is added into a reaction kettle in which water is added in advance, then polysaccharide enzymes are added, and enzymolysis is performed; step S3: proteolysis: adding sodium carbonate to adjust pH, adding compound protease into the reaction kettle, and performing enzymolysis; and S4, conveying the wet material to a spray drying tower for spray drying. According to the method, the pea powder syrup protein powder, the wheat protein powder and the soybean concentrated protein powder are used as raw materials, through dispersion, enzymolysis and spray drying, flavor substances are generated, the bitter taste is eliminated, the palatability of plant protein is remarkably improved, the strong food calling performance is shown in feeding experiments of piglets and cats, and the method is few in steps, mild in reaction condition and low in cost.

The invention provides a traditional Chinese medicine additive for improving the survival rate of piglets and a preparation method and application thereof, and belongs to the technical field of feed additives. The traditional Chinese medicine additive provided by the invention is Qibai tonifying powder and comprises the following raw materials in parts by weight: 20-30 parts of radix astragali, 15-25 parts of rhizoma atractylodis macrocephalae, 10-20 parts of pericarpium citri reticulatae, 10-15 parts of radix saposhnikoviae, 15-25 parts of folium cortex eucommiae, 10-15 parts of malt, 10-15 parts of cortex magnoliae officinalis, 5-10 parts of poria cocos, 5-10 parts of rhizoma dioscoreae and 5-10 parts of folium perillae. The Qibai tonifying powder provided by the invention improves the immunity of piglet organisms, promotes digestion and absorption, enhances the anti-stress ability of piglets and reduces piglet diarrhea through the synergistic effect of invigorating spleen and tonifying qi, strengthening superficies and resisting evil and strengthening tendons and bones, thereby achieving the purpose of increasing the survival rate of piglets.

The invention provides kitten formula milk powder produced by a dry method, and relates to the technical field of pet formula food. The formula milk powder for kittens is prepared from goat milk powder, whey protein powder, grease powder, compound minerals, compound vitamins, choline, taurine, docosahexaenoic acid powder and arachidonic acid powder, and the compound minerals contain sodium, potassium, copper, magnesium, iron, zinc, manganese, calcium, phosphorus, iodine and selenium. The compound vitamins contain vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, nicotinic acid, folic acid and biotin. According to the invention, the defects in the prior art are overcome, dry production of the milk powder is realized through compounding of multiple components and embedding of grease, and growth and development of kittens are further promoted on the basis of effectively ensuring nutritional ingredients.

The invention discloses a traditional Chinese medicine composition for treating inflammatory bowel disease as well as a preparation method and application thereof, and belongs to the technical field of medicines. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 15-17 parts of radix pulsatillae, 10-12 parts of cortex fraxini, 10-12 parts of wine-processed rhizoma coptidis, 30-32 parts of cortex phellodendri, 15-17 parts of radix paeoniae alba, 10-12 parts of radix angelicae sinensis, 10-12 parts of radix aucklandiae and 10-12 parts of liquorice root. The traditional Chinese medicine composition provided by the invention is prepared from natural medicines, has low side effects, and provides a new choice for rehabilitation treatment and prevention of patients with inflammatory bowel diseases.

This invention provides a fermented milk yogurt for infants, which, by weight, consists of the following ingredients: 300-450 parts fermented milk, 80-120 parts compound fresh fruit puree, 20-40 parts concentrated fruit juice, 10-20 parts compound dietary fiber, 15-30 parts protein components, and 5-15 parts cereal powder. This invention introduces five specific proportions of compound probiotics for fermentation, including *Bifidobacterium animalis* subsp. *lactobacterium* HN019, *Lactobacillus fermentum* CECT5716, *Lactobacillus rhamnosus* HN001, *Bifidobacterium breve* M-16V, and maltodextrin. These five strains produce a significant synergistic effect, not only shortening the fermentation time and increasing the number of live bacteria in the fermented milk, but also forming a more complete intestinal flora barrier in infants, effectively promoting nutrient absorption and reducing the incidence of diarrhea and constipation in infants.

The invention discloses a humic acid adhesive and a preparation method thereof.The humic acid adhesive is prepared from, by weight, 70-80 parts of sodium humate, 10-15 parts of calcium chloride and magnesium chloride saturated solution, 10-15 parts of amino acid and 900-1100 parts of water.The humic acid adhesive is wide in raw material source and simple in preparation process, the sodium humate serves as a molecular basis, and the humic acid adhesive is prepared from the sodium humate, the calcium chloride and magnesium chloride saturated solution, the amino acid and the water. Sodium humate molecules are continuously polymerized to form reticular macromolecules through bridging and Maillard reaction, and feed raw materials such as starch and protein are wrapped and bonded in the feed granulation process, so that the hardness of feed particles can be remarkably improved, the pulverization rate can be reduced, and the production cost can be reduced. The humic acid adhesive with the mass ratio of 0.1-0.2% is applied to preparation of the feed, the obtained humic acid adhesive feed can be rapidly decomposed in animal intestines, the burden of the animal intestines and digestion is not increased, and the humic acid adhesive feed is an animal-friendly adhesive.

The invention relates to application of a furostanol dioscin compound shown in a general formula (I) in preparation of a selective SGLT-2 (sodium-glucose cotransporter 2) inhibition medicine, and further relates to a medicine composition containing the compound. The compound and the pharmaceutical composition containing the compound can treat diseases such as diabetes mellitus and / or heart failure by selectively inhibiting SGLT-2. # imgabs0 #

The invention relates to a composition for enhancing the treatment efficiency of mesenchymal stem cells and application, and belongs to the technical field of cell drug treatment. The composition for enhancing the treatment efficiency of the mesenchymal stem cells comprises a PARP inhibitor and an inflammatory factor. Mesenchymal stem cells are pretreated by the composition to obtain the mesenchymal stem cells with enhanced treatment efficiency, and the mesenchymal stem cells are used for preparing drugs for treating immune diseases characterized by abnormal inflammatory reaction. The PARP inhibitor is combined with the inflammatory factor to treat the mesenchymal stem cells, so that the intracellular signal transduction and transcriptional activator protein 1 (STAT1) phosphorylation level can be improved, and the expression of immunosuppressive factor indoleamine dioxygenase 1 (IDO1) and programmed cell death ligand 1 (PD-L1) can be increased, thereby enhancing the immune regulation function of the stem cells; and a gain effect of treating immune diseases with abnormal inflammatory reaction as a main characteristic is realized.

The invention relates to the technical field of traditional Chinese medicines, in particular to application of a traditional Chinese medicine composition in preparation of a medicine for preventing and treating virus infectious diarrhea. The traditional Chinese medicine composition comprises one or a combination of more than two of 1-100 parts of mangnolia officinalis, 1-100 parts of scorched betel nut, 1-100 parts of roasted amomum tsao-ko, 1-100 parts of ephedra, 1-100 parts of semen armeniacae amarae, 1-100 parts of notopterygium root, 1-100 parts of ginger, 1-100 parts of pogostemon cablin, 1-100 parts of eupatorium, 1-100 parts of rhizoma atractylodis, 1-160 parts of poria cocos, 1-120 parts of bighead atractylodes rhizome, 1-100 parts of gypsum, 1-100 parts of scorched hawthorn fruit, 1-100 parts of scorched medicated leaven, 1-100 parts of scorched malt, 1-100 parts of earthworm, 1-100 parts of cynanchum paniculatum, 1-100 The traditional Chinese medicine composition can obviously improve the treatment effect, the relieving rate of abdominal pain and diarrhea symptoms of a subject is also obviously improved, and the traditional Chinese medicine composition has clinical popularization value.

The application provides a feed processing method of expired instant noodles and belongs to the technical field of feed.The expired fried instant noodle cake is crushed, and then subjected to enzymolysis by lipase; then subjected to enzymolysis by composite enzyme, and then subjected to aerobic solid state fermentation by adding a seasoning bag and composite probiotic preparation, ultraviolet irradiation, liquid anaerobic fermentation by composite probiotic preparation micro-voltage transient pulse light irradiation; the fermented material is filtered to obtain supernatant, and the supernatant is a composite organic acid feed additive rich in organic acid and probiotic; the filter residue is uniformly mixed with sodium chloride and rice husk powder, and then extruded and granulated to prepare biological feed rich in bacterial protein and nucleotides.The application fully utilizes the substances such as carbohydrates, oils and fats and table salt in instant noodles, and converts them into composite organic acid feed additive rich in organic acid and probiotic and biological feed rich in bacterial protein and nucleotides, so that the health of livestock and poultry is promoted and high efficiency is achieved.

The invention discloses application of orange peel hydrolat in preparation of feed, feed additives and drugs. Relates to the technical field of plant extracts. The influence of the orange peel hydrolat on the growth performance, diarrhea rate, organ index, blood routine, serum antioxidant index and liver and jejunum structures and functions of the broiler chickens is researched, and the result shows that the growth performance of the broiler chickens can be remarkably improved and the incidence rate of diarrhea can be reduced by adding a certain dosage of orange peel hydrolat into the feed; meanwhile, the level of inflammatory factors is reduced, the level of immune factors and the activity of antioxidant enzymes are improved, inflammatory response and oxidative stress are reduced, and liver tissue and intestinal mucosa are protected, so that the integrity and functions of the liver and the intestinal tract are recovered. The results show that the broiler bacterial diarrhea can be effectively improved by adding a certain dose of orange peel hydrolat into the feed, and the mechanism of the orange peel hydrolat may be mainly related to the activation of the intestinal immune system and the reduction of inflammatory response.

This invention discloses a method for preparing soft-particle starter feed based on low-temperature curing and microencapsulation, belonging to the field of livestock and poultry feed preparation technology. The method includes basic raw material pretreatment, low-temperature curing, mixing and blending, soft-particle molding, drying and cooling, and screening and packaging steps. The core lies in employing a process of "low-temperature curing + double-layer microencapsulation + soft-particle molding," combined with an excipient system composed of modified chitosan, sodium alginate, and attapulgite solution. Low-temperature curing preserves heat-sensitive nutrients and kills harmful microorganisms; double-layer microencapsulation enables targeted release of core functional components, ensuring their activity; soft-particle molding balances palatability and intestinal protection; and the various components of the excipients synergistically improve feed stability, probiotic colonization rate, and digestibility.