4 results about "Living sample" patented technology

Systems and methods are provided for automated incubation of large numbers of tumor organoids or other volumetric biological samples cultured from cells or other tissues. Label-free, non-destructive imaging of the samples is performed quickly and at high temporal resolution (e.g., once per day or more), allowing interventions (like the addition or subtraction of substances like water, glucose, buffers, or pharmaceuticals) to be applied to each sample based on the images, facilitating closed-loop per-sample control of sample growth. This can lead to improved incubation outcomes, like increased rates of generation of live samples and control of sample size or other sample properties. Image and other incubation data obtained via such automated incubation processes can be used to train machine learning models to plan interventions for the samples, further increasing incubation success rates and allowing for the incubation of rare and / or novel samples, for which reliable incubation protocols do not yet exist.

The invention relates to a running water type live insect detection device and a detection method, which can realize automatic running water type live insect detection on the premise of not damaging insects as far as possible, provide a living sample basis for researches on behavior habits, growth and development and the like of the insects, help to deeply understand insect ecology and provide a reliable basis for accurate pest control. The running water type live insect detection system which is independently designed has good functionality and practicability. All important parts of the device are designed to be movable and detachable, the coupling of part connection is greatly improved through the structural design, the overall structure is more reasonable, and the overall operation efficiency of the system is effectively improved. The insect pest monitoring device has high realizability in the aspects of overall manufacturing and assembling, large-scale production, popularization and application are facilitated, the insect pest monitoring device can be rapidly put into actual agricultural production and insect pest monitoring work, and powerful support is provided for agricultural intelligent development.

This invention discloses a four-dimensional Raman monitoring system and dynamic quantitative method for environmental microplastics in vivo, belonging to the field of environmental ecological monitoring and analysis technology. The system includes a confocal spectroscopy acquisition module, a controller, and a data processing module. It acquires the three-dimensional coordinates of live samples through coordinated spatial scanning and simultaneously acquires Raman signals to construct four-dimensional spectral data. A multidimensional convolutional instance segmentation network is used to process the four-dimensional Raman spectral data, identifying and classifying endogenous biological matrices and exogenous multi-mixed microplastics in vivo, outputting voxel-level semantic classification results, and then quantitatively calculating the absolute retention volume and abundance of microplastics in the organism. This invention overcomes the shortcomings of existing technologies in label-free quantification under complex biological backgrounds, achieving in-situ accurate identification of mixed microplastics in vivo, and providing a standardized quantitative monitoring method for assessing the bioaccumulation, metabolic patterns, and ecotoxicological effects of environmental microplastics.

The utility model relates to the technical field of zooplankton sorting, and discloses a zooplankton living body sample automatic sorting device which comprises a box body, partition plates are fixedly connected to the two sides of the inner wall of the box body, a sorting cavity is formed in an inner cavity, located between the partition plates, of the box body, and collecting cavities are formed in the box body and located on the two sides of the sorting cavity. A filtering assembly is mounted in an inner cavity of the sorting cavity and is used for filtering a living body sample; according to the automatic sorting device for zooplankter living body samples, a first filter plate is used for filtering, zooplankter living bodies stay in an inner cavity of a sorting cavity, along with filtering, the concentration of the living bodies in the inner cavity of the sorting cavity is increased, at the moment, the first filter plate moves upwards, so that the living bodies and water are driven to move upwards, and in the process, a pressing plate slides towards an inner cavity of a sleeve plate; the collecting cavity is opened, then high-concentration living bodies above the first filter plate can enter the inner cavity of the collecting cavity along with water, separation is easy and convenient, extra force is not applied to the living bodies, and the survival rate of the living bodies is increased.