72results about How to "Increase penetration depth" patented technology

The invention discloses a composite reinforcement type suction barrel device based on microorganism induction and a use method thereof. The composite reinforcement type suction barrel device based on microorganism induction comprises a suction barrel model system, a microorganism cement reinforcement system and a test monitoring system. The suction cylinder model system comprises a suction cylinder, a grouting pipeline and hydraulic equipment, and the grouting pipeline is laid on the inner wall of the suction cylinder and used for injecting microorganism cement grout; the hydraulic equipment is connected to the suction barrel and used for controlling lifting and pressing-in of the suction barrel. The microbial cement reinforcement system comprises liquid storage equipment and negative pressure equipment, and the liquid storage equipment is connected to the grouting pipeline and used for storing and providing microbial cement grout for the grouting pipeline; the negative pressure equipment is connected to the suction barrel and used for applying negative pressure to the interior of the suction barrel in the grouting process, and permeation of microorganism cement grout is promoted. The test monitoring system is used for testing mechanical parameters of a soil body, monitoring the suction barrel and carrying out a loading test on the suction barrel.

The invention provides an NIR-IIb / c rare earth nanoparticle fluorescent probe as well as a preparation method and application thereof. The fluorescent probe sequentially comprises a core, an active shell and an inert shell from inside to outside, wherein the core comprises Tm < 3 + > ions and Er < 3 + > ions, and the active shell comprises Er < 3 + > ions, Yb < 3 + > ions and Ce < 3 + > ions. The fluorescent probe provided by the invention has an efficient energy transfer system, not only has bright luminescence in an NIR-IIb wave band (1500-1700 nm), but also has luminous intensity increased by dozens of times in an NIR-IIc wave band (1700-1900 nm) compared with that of a traditional probe. The hydrophilic modification method of the probe is also improved, and the biocompatibility of the probe is improved by a multi-layer polymer cross coating method, so that the probe still has good luminescence property in an organism, and the penetration depth and resolution of biological tissues during imaging are improved.

The invention belongs to the field of personal care, and particularly relates to a glycoside derivative flexible liposome and a preparation method and application thereof, the glycoside derivative flexible liposome comprises a main shell material, a humectant, a wrapped raw material, an auxiliary shell material, a preservative and a solvent; the main shell material is phosphatidylcholine, and the auxiliary shell material is polyquaternium-51; the preservative is any one or more of 1, 2-hexanediol, p-hydroxyacetophenone, methylparaben, phenoxyethanol and caprylyl glycol; the moisturizing agent is butanediol; the wrapped raw material is hydroxypropyl tetrahydrofurantriol; the solvent is deionized water. According to the invention, the permeability and penetration depth of the glassine and the concentration of the glassine at a target position are improved by utilizing a flexible liposome wrapping technology, the bioavailability of the glassine is improved, and the addition amount is reduced under the condition of realizing the same tightening and anti-wrinkle effects, so that the cost is reduced.

The invention provides a cast iron sand mold coating and a preparation method thereof, and relates to the field of casting sand mold coatings. The cast iron sand mold coating is composed of the following raw materials: a fireproof filler, a liquid carrier, a suspending agent, a binder and an auxiliary agent. The raw materials comprise, by weight, 65-70% of the fireproof filler, 19-25% of the liquid carrier, 2-4% of the suspending agent, 4.4-5.5% of the binder and 2.4-3% of the auxiliary agent; the refractory filler is composed of magnesia powder, zircon powder and graphite powder; the magnesia powder is composed of light magnesia powder and heavy magnesia powder. According to the cast iron sand mold coating and the preparation method thereof, the problems that an existing shielding type coating is thin in anti-sulfuration coating thickness, poor in anti-sulfuration coating stability, general in anti-sulfuration effect and large in gas forming amount can be effectively solved, poor spheroidization and casting defects of castings are effectively avoided, the production cost is reduced, and the stability of the castings is improved.

The invention relates to a method for reinforcing unearthed water-saturated decayed bone keratin cultural relics, in particular to a method for reinforcing unearthed water-saturated decayed bone keratin cultural relics by using three-dimensional net-shaped hydroxyapatite, which comprises the following steps: 1) dehydrating the bone keratin cultural relics in an environment with constant temperature and humidity; (2) adding a calcium source solution into the surface of the obtained dehydrated bone keratin cultural relic, and carrying out dehydration treatment in an environment with constant temperature and humidity; (3) a phosphorus source solution is added to the surface of the dehydrated bone keratin cultural relic obtained in the step (2), and dehydration treatment is conducted again in the environment with the constant temperature and humidity; and 4) repeating the steps 2) to 3) for multiple times. Compared with the prior art, the calcium source and the phosphorus source are used for reinforcing the bone keratin cultural relics, three-dimensional net-shaped hydroxyapatite is generated in cracks of the bone keratin cultural relics, the reinforcing effect is effectively improved, safe dehydration and reinforcing of the unearthed water-saturated rotten bone keratin cultural relics are achieved, and the risk that the cultural relics disintegrate due to excessive water loss or excessive water replenishing is avoided.

The invention provides a transcranial light adjusting method and system based on a laser light source and transmitting energy through an optical fiber bundle, relates to the technical field of physiotherapy, and mainly comprises a power supply, a controller, a laser, an optical fiber coupler, the optical fiber bundle, a lens group and the like. The optical fiber coupler couples laser output by the laser into the incident end of the optical fiber bundle; the emergent end of the optical fiber bundle is set as one or more sub optical fiber bundles, and the tail end of each sub optical fiber bundle is selectively butted with one lens group; when the emergent end of the optical fiber bundle is provided with a plurality of sub optical fiber bundles, the plurality of sub optical fiber bundles are respectively and correspondingly arranged at the back of the prefrontal lobe, the belly of the prefrontal lobe, the temporal lobe, the apical lobe and other physiotherapy positions which are effective for light; and when the tail ends of the plurality of sub-optical fiber bundles are not butted with the lens group, the emergent end of each sub-optical fiber bundle is set as an optical fiber array, and the optical fiber array is embedded into the light supply effective head position and is in contact with the scalp, so that the absorption rate and the reflectivity of the hair to near-infrared light are reduced.

The utility model belongs to the technical field of glue curing equipment, and discloses a deep UV (ultraviolet) glue curing device, which is characterized in that a conveying device is mounted at the upper end of a support frame, a curing oven is fixedly connected with the support frame, the conveying device penetrates through the middle of the curing oven, and the curing oven comprises an upper shell and a lower shell; a first ultraviolet curing light source is installed on the inner side of the upper shell through a fixing base, and a second ultraviolet curing light source is installed on the inner side of the lower shell through a fixing base. The first ultraviolet curing light source and the second ultraviolet curing light source are respectively connected with a power regulator through a connecting line, and the power regulator is connected with a control panel through a connecting line. By adopting the double-layer light source, the power regulator and the control panel, the penetrating power and the irradiation uniformity of ultraviolet rays are improved, and the accurate control on the irradiation intensity is realized, so that the curing effect of deep glue is improved, and the product quality is improved.

The invention belongs to the technical field of luminescent materials, and discloses an up-conversion nano material as well as a preparation method and application thereof. The up-conversion nano material comprises a core, the element composition of the core is NaErF4: Nd, Yb and Ce, and the molar weight of Nd accounts for 2%-15% of the total molar weight of rare earth elements of the core; the core is coated with a middle shell, the element composition of the middle shell is NaYF4: Yb, and the molar weight of Yb accounts for 20%-100% of the total molar weight of rare earth elements of the middle shell; the outer part of the middle shell is coated with a passivation shell, and the element composition of the passivation shell is NaYF4. According to the up-conversion nano material, through fine ion doping and a unique energy transfer mechanism, efficient up-conversion blue and ultraviolet light emission of Er < 3 + > can be achieved; the preparation method of the up-conversion nano material is simple in process, easy to operate, low in cost, short in period and suitable for mass production.

The invention relates to an efficient coal gangue aggregate modification method and device based on a microbial mineralization technology. The method comprises the following steps: selecting a mineralized microbial strain: selecting a mixed bacterium of bacillus pasteurii and bacillus coelii as the mineralized microbial strain; forming a microbial mineralization system; pretreating the coal gangue; dynamic mineralization treatment: immersing the coal gangue aggregate into a microbial mineralization system, placing a coal gangue aggregate suspension, and ensuring that the bottom of the coal gangue aggregate is suspended; maintaining the mineralizing solution in a circular flow state, so that the mineralizing solution can be in full contact with the surface of the aggregate and permeate into internal pores, and maintaining the circular flow state of the mineralizing solution for 5-10 days; and cleaning and drying. According to the method, continuous circulating flow of the mineralizing solution on the surface of the coal gangue aggregate and in internal pores is achieved through the power circulating system, formation of a biological membrane in the static soaking process is effectively avoided, the penetration depth and deposition uniformity of the mineralizing solution are improved, and the method has good industrial application prospects.

The invention discloses a moisturizing anti-wrinkle polypeptide composition as well as a preparation method and application thereof, and relates to the technical field of daily chemical materials. The invention discloses a preparation method of a moisturizing and anti-wrinkle polypeptide composition, which comprises the following steps: uniformly stirring meadowfoam seed oil, caprylic acid / capric acid / succinic triglyceride and polypeptide liposome to obtain the moisturizing and anti-wrinkle polypeptide composition, wherein the polypeptide liposome is prepared by taking a combination of soybean lecithin, modified cholesterol and cholesterol as a capsule material and taking acetyl hexapeptide-8, snake venom peptide and a blue copper peptide compound as a core material through an ethanol injection method. The modified cholesterol is obtained by modifying cholesterol, the modified cholesterol is added into the capsule material, the defects that an existing liposome material is prone to aggregation and leakage, poor in stability and the like are effectively overcome, and the prepared material is good in stability, capable of being slowly released, high in skin retention amount and capable of being more easily absorbed by skin cells; the function of obviously delaying skin aging is realized.

The invention discloses a fused ring tin porphyrin photosensitizer with high singlet oxygen sensitization efficiency and photothermal effect, and relates to the technical field of biological medicine. The invention provides a structural general formula and a preparation method of a fused ring tin porphyrin photosensitizer. According to the invention, the photosensitizer is endowed with strong absorption capacity in an NIR region through an isoquinoline fused ring on the periphery of porphyrin, < 1 > O2 sensitization activity and photothermal effect of the photosensitizer under light excitation are promoted through metal tin coordination in a parent nucleus, and an efficient photodynamic / photothermal synergistic killing effect on 4T1 cells of a mouse breast cancer cell line under NIR light irradiation is realized; the problems of poor light stability, reduced photosensitive activity and the like in the prior art are effectively solved.

The invention discloses a gas-driven electric shock needle type electric shock bomb which comprises a bomb shell, a bomb body, a launching assembly, a power supply assembly, an electric shock assembly and a needling assembly. The cartridge case is in a rotary body shape, the cartridge body is arranged in the cartridge case, the cartridge body is a three-step cylinder and comprises a first cylinder, a second cylinder and a third cylinder from top to bottom, the needling assembly is arranged on the upper end face and the side face of the first cylinder, the electric shock assembly is arranged in the first cylinder, the power supply assembly is arranged in the second cylinder, and the launching assembly is arranged in the third cylinder; the needling assembly comprises an air pushing needle, the section of a needle body of the air pushing needle is rectangular, a needle tip part is an inclined cutting edge, and the length of the air pushing needle is adjustable; the ballistic performance in the projectile body is stable by applying a high-low pressure launching technology; insurance of the pneumatic push rod and the conductive push rod before ammunition goes out of the chamber is achieved through the insurance block; after the safety is relieved, the gunpowder gas pushes the gas push rod and the conductive push rod to realize gas push needle movement and electric shock module work; the space dislocation anti-pulling needle on the projectile body can cause secondary electric shock when the target touches the electrode.

The present invention relates to the technical field of food processing, and discloses a temperature and vacuum pressure adjustable poultry egg pickling reactor, which comprises: a storage mechanism used for storing poultry eggs and injecting a pickling liquid in a closed environment to pickle the poultry eggs, the storage mechanism comprises a reaction container and a plurality of groups of partition plates, the partition plates are slidably connected to the interior of the reaction container, and the reaction container is used for storing the poultry eggs; the reaction container is used for storing pickling liquid, and the partition plate is used for storing poultry eggs; the pressure regulating mechanism is arranged on the outer side of the storage mechanism and used for controlling the air pressure in the storage mechanism, so that the interior of the storage mechanism is continuously and repeatedly converted between negative pressure and normal pressure; the temperature control mechanism is arranged on the outer side of the storage mechanism and is used for adjusting the temperature of the pickling liquid in the storage mechanism. Through temperature and pressure regulation and decentralized design, the pickling uniformity and efficiency are improved, loading and unloading of poultry eggs are simplified, operation damage is avoided, bacterial reproduction is effectively inhibited, and various pickling requirements are met.

The invention provides nano microspheres for targeted delivery of siRNA based on SFTSV-Gn and application of the nano microspheres, and belongs to the technical field of antiviral drugs. SiRNA is optimally designed, a nano microsphere delivery system is a nano compound formed by assembling optimally designed siRNA and cell-penetrating nano arginine, and the nano microspheres are used as a delivery carrier of siRNA to protect siRNA from enzymatic degradation, so that the siRNA delivery efficiency is improved, and the siRNA delivery efficiency is improved. And the target cells can be promoted to uptake, the replication of new bunyavirus RNA (Ribonucleic Acid) can be effectively inhibited, the injury of liver and lung tissues can be improved, and the survival rate can be increased. In addition, the surface-modified nano-microspheres have the advantages of high targeting, deep penetration, non-invasiveness and the like, and have wide application prospects in the antiviral field.

This invention discloses a snapshot-type hyperspectral three-dimensional skin imaging method and device, belonging to the field of biomedical imaging technology. The method includes: constructing a snapshot-type spectral-light field coupled imaging system containing a light source and an acquisition model; achieving full-domain skin illumination with broadband illumination; synchronously coupling and acquiring spectral and three-dimensional spatial information through the synergistic action of a lens group and a hyperspectral sensor to generate spectral coupled light field data; establishing a correlation dataset between the spectral coupled light field image and the hyperspectral light field image; training a spectral reconstruction network and solving the data; reconstructing the hyperspectral light field image and obtaining multi-view images through macro-pixel sampling; using a light field super-resolution network to improve image resolution; selecting the optimal skin penetration band image for stereo matching to obtain a target band depth map; and fusing the high-resolution center-view images from each channel with the target band depth map to complete the generation of a hyperspectral three-dimensional image. This invention achieves single-exposure hyperspectral three-dimensional imaging of the superficial skin layer.

The utility model provides a device of adding anti -caking agent before static atomization coupling type fluidized bed in potassium chloride production, including vibration feeder and static atomizer, and vibration feeder includes feeder body, is provided with vibration motor on feeder body, and feeder body is connected with support frame through composite damping system, still be provided with opening on feeder body, and static atomizer includes the multi -hole nozzle corresponding to the opening setting. According to the device of adding anti -caking agent before static atomization coupling type fluidized bed in potassium chloride production of the utility model, not only can the anti -caking agent be evenly sprayed on the salt particle surface, but also can ensure that the salt particle is fully loose in the conveying process, and further improve the uniform distribution effect of anti -caking agent addition.

The molecular weight and the emission wavelength of the dye are balanced through a reasonable strategy, a series of compact organic small molecule dyes with the emission wavelength from a visible light window to a second near-infrared window are obtained, the universality is good, and the good blood brain barrier crossing capacity is achieved. According to the invention, a low-molecular-weight flexible conjugated polyene chain is creatively selected as a pi electron bridge, so that the extension of a pi conjugated system can be effectively realized, the small molecular weight of the dye can be maintained, and moreover, the conjugated polyene chain is used for prolonging a pi-conjugated structure to enhance an ICT effect, so that the dye has a good application prospect. The red shift of the emission wavelength can be realized while the molecular weight is kept small. Therefore, on the basis of the p-hydroxybenzylidene-imidazolinone chromophore, an ICT effect is synergistically enhanced through an integrated molecular design strategy, a series of small-molecular-weight fluorescent dyes with a D-pi-A1 or D-pi-A1-pi-A2 structure are constructed, the maximum wavelength can reach 1200 nm or above, the blood-brain barrier permeability of the dye as a probe is ensured, and the fluorescent dye can be used for detecting the blood-brain barrier permeability of the probe. The method can be applied to in-vivo in-situ brain imaging.

This invention belongs to the field of rare-earth luminescent materials and optical sensing technology, specifically disclosing an upconversion temperature probe excited by NIR-I, its preparation method, and its application. The probe includes a matrix core material, which is a fluoride crystal; and dopant ions, specifically holmium ions (Ho) doped into the matrix core material. 3+ Ho 3+ As the sole luminescent center, it is excited by a near-infrared I light source with a wavelength of 880-920 nm to generate Ho. 3+ Characteristic green upconversion luminescence and red upconversion luminescence. This invention employs the aforementioned NIR-I excited upconversion temperature probe, its preparation method, and its application, utilizing Ho... 3+ The unique energy level competition mechanism of ions enables high-sensitivity temperature measurement over a wide temperature range, and the temperature measurement signal is unaffected by fluctuations in excitation power.

The invention discloses a salt-light alkali-reducing cultivation method for cotton in saline-alkali soil, and relates to the technical field of cotton planting. Comprising the following steps: deeply ploughing a cotton field, applying a base fertilizer, and irrigating to make entropy to obtain a to-be-sown cotton field; cotton sowing is carried out by adopting a direct-seeding plastic film mulching method and a machine-harvested cotton planting mode, the sowing depth is controlled to be 2.5-3.5 cm, the soil covering width is 5-7 cm, the soil covering thickness is 0.5-1 cm, the one-grain rate is larger than or equal to 95%, and the hole rate is smaller than or equal to 3%; after-sowing management is conducted in the cotton seedling stage, timely intertillage is conducted, and meanwhile leaf fertilizer is sprayed according to the cotton cotyledon stage to the two-leaf stage, the 3-4-leaf stage and the 4-leaf stage; performing water and fertilizer management in a cotton bud stage, performing intertillage, and performing foliage dressing at the same time; in the cotton flowering and boll-forming period, water dripping fertilizer is conducted according to the entropy condition, topping is conducted in good time, meanwhile, fertilizer is applied to regulate and control the plant type, and fertilizer is applied according to the premature senility trend and the snooze growth vigor; disease, pest and weed control is carried out in the sowing period. The cultivation method is suitable for saline-alkaline cotton fields in Xinjiang and is an effective means for increasing the cotton yield and improving soil conditions.

The application provides a suspension agent containing pyriproxyfen and clothianidin, which comprises pyriproxyfen 3-8%, clothianidin 30-40%, clove extract 1-1.5%, and astragalus polysaccharide 0.5-1% according to percentage by weight; and the weight ratio of the clove extract and the astragalus polysaccharide is 3:2. The suspension agent provided by the application has good wetting property, strong soil permeability, can improve the effective utilization rate of the liquid medicine, and improves the drug efficacy.

The invention discloses a dose distribution optimization device and method for a bidirectional large-angle focusing VHEE beam, and relates to the technical field of electron beam transmission. Quadrupole lenses are arranged at intervals along the beam emission direction; the front n-2 quadrupole lenses enlarge the envelope of the beam; the size of the (n-1) th quadrupole lens in the transverse focusing direction can accommodate the envelope of the beam; when the beam passes through the nth quadrupole lens, envelope is subjected to defocusing action, the beam output requirement is just met, and the bidirectional large-angle focusing VHEE beam of the beam is output; and different target dose distributions are obtained by adjusting the magnetic field gradients of the last two quadrupole lenses. According to the invention, two quadrupole lenses closest to an outlet hole are both taken into consideration, so that the dose distribution effect is further optimized; and a larger focusing angle can be obtained by adopting bidirectional large-angle focusing, so that the dose before the focus is more dispersed, and the dose at the focus is more prominent.

The invention relates to the field of concrete waterproof materials, in particular to an inorganic silicon deep permeable crystallization waterproof agent and a preparation process. The invention discloses an inorganic silicon deep permeable crystallization waterproof agent, which is prepared from the following raw materials in parts by mass: 40 to 60 parts of active sodium silicate, 20 to 35 parts of nano composite particles, 10 to 15 parts of aluminate cement, 1 to 3 parts of coagulation accelerator, 5 to 15 parts of dispersing agent, 3 to 5 parts of thickening agent, 0.1 to 0.3 part of preservative and 40 to 65 parts of deionized water. According to the inorganic silicon deep permeable crystallization waterproof agent and the preparation process provided by the invention, the finally prepared waterproof agent not only has excellent waterproof and anti-corrosion properties, but also can further improve the penetration depth, temperature resistance and aging resistance of the inorganic silicon waterproof agent in concrete; therefore, the waterproof agent has good long-term waterproof performance, can adapt to various application environments, and has very excellent application prospects.

The application relates to the technical field of industrial control systems, in particular to a multi-data real-time acquisition control system for wheat moistening, which comprises a segmented water injection control unit, which is used for controlling a water injection actuator according to a segmented water injection proportioning scheme, so as to inject water into wheat in a stirring or turning material state in multiple small-dose interval modes; and a moisture content calculation unit, which is used for introducing a moisture content index, collecting second data in the segmented water injection and wheat moistening standing stages, analyzing moisture distribution differences and time change trends of the wheat at different positions according to the second data, and calculating the moisture content index of the current batch of wheat according to a moisture content evaluation model. The moisture content index of the current batch of wheat is calculated according to the moisture content evaluation model, and the threshold value judgment unit compares the moisture content index with a preset moisture content target threshold value; when the threshold value is reached, a wheat moistening completion instruction is automatically output; and when the threshold value is not reached, an adjustment strategy is generated according to a moisture content index deviation and a multi-parameter change.

The invention relates to the technical field of medical instruments, in particular to a low-intensity pulsed ultrasound instrument for relieving ulcerative colitis inflammation and application of the low-intensity pulsed ultrasound instrument for relieving ulcerative colitis inflammation, low-intensity pulsed ultrasound can effectively reduce inflammatory response of the whole body in intervention treatment and relieving of ulcerative colitis, the conditions of weight loss, loose and loose excrement and stool bleeding are improved, and the treatment effect of ulcerative colitis is improved. The traditional Chinese medicine composition can be used for treating ulcerative colitis, improving the disease activity index (DAI) and improving the life quality of a patient in the acute attack period, has the advantages of no trauma, few side effects, high penetration depth and easiness in home operation of the patient, and provides brand-new effective treatment equipment for ulcerative colitis.

The application belongs to the technical field of hazardous waste pollution control, and discloses a synergistic penetration stable-effect fly ash selenium-fixing composite chelating agent and application thereof. The chelating agent is composed of the following components in percentage by mass: piperazine compound 10-30%, ferrous sulfate 15-35%, penetrating agent 3-12%, and borax-sodium hydroxide buffer 40-70%. In preparation, ferrous sulfate is dissolved in the buffer at room temperature, then the piperazine compound is added and stirred, and finally the penetrating agent is added, heated to 40-50 DEG C, and stirred for preservation, to obtain a red-brown transparent liquid with pH 9.5-11.5. The application realizes efficient and stable fixation of various forms of selenium in fly ash through the multi-mechanism synergy of penetrating agent reinforced diffusion of the medicament in fly ash micropores, a stable alkaline environment maintained by the buffer system, and Fe 2+ reduction precipitation and piperazine chelation adsorption, and the selenium leaching concentration of the treated fly ash is ≤0.1 mg / L, meeting the standard and having long-term stability.

The invention discloses a tension leg platform suction pile anchoring foundation and an offshore construction method, and relates to the technical field of ocean engineering. The base structure is fixed to the top of the mud entering steel structure. The base structure is of a double-wall cylindrical structure, a ballast tank is arranged in the base structure, and a ballast system is arranged in the ballast tank; a drainage pipeline is further arranged in the base structure and communicates with the interior of the mud inlet steel structure and the water suction pump. A lug plate structure is arranged on the side wall of the base structure; the mud entering steel structure is of a single-layer wall cylindrical structure, and the cylindrical opening direction of the mud entering steel structure is opposite to the cylindrical opening direction of the base structure; and a to-be-mounted counterweight is placed in the upper opening structure of the base structure. The technical problem that a traditional suction pile anchoring foundation is not suitable for a tension leg type floating platform including a floating wind power platform due to the fact that the axial pulling resistance capacity is limited by a suction barrel structure type, an installation mode and soil conditions is solved.

The application provides a medical waste high-temperature steam permeation control treatment method, relates to the field of harmless treatment of medical waste, and comprises the following steps: loading medical waste in a treatment cabin and performing vacuumization on the treatment cabin, so that the pressure in the treatment cabin is reduced to a first target negative pressure value; saturated steam is injected into the treatment cabin, and a multi-stage gradient pressure increasing program is performed, so that the working pressure of the treatment cabin is maintained in a slightly positive pressure state in which a slightly positive pressure offset of the target sterilization pressure is increased; the target sterilization temperature in the slightly positive pressure state is maintained to perform basic heat penetration, and the treatment cabin is subjected to periodic pressure pulse cycle treatment; the target sterilization temperature in the slightly positive pressure state is maintained to perform final sterilization, the treatment cabin is subjected to vacuum drying and air injection into the treatment cabin for cooling, and the treatment cabin is opened to unload the treatment product.

The invention discloses a near-infrared two-region fluorescent molecule and a preparation method thereof. The 4, 8-bis [5-(2-ethylhexyl)-2-thienyl-3-(2-ethylhexyl)-2-thienyl]-dithiadiazole near-infrared two-region fluorescent molecular contrast agent is prepared by using the method, and is based on 4, 8-bis [5-(2-ethylhexyl)-2-thienyl-3-(2-ethylhexyl)-2-thienyl]-dithiadiazole. The fluorescent molecule is formed by coupling reaction of a near-infrared second-region fluorescent molecule taking 2, 8-bis [5-bromo-3-(2-ethylhexyl)-2-thienyl]-dithiadiazole as an electron acceptor structural unit and 2-ethylhexyl-5-trimethyltin thiophene Stille, so that the obtained fluorescent molecule has high penetration depth and high-resolution fluorescence imaging capability in a near-infrared second region (NI R-I, 1000-1700 nm).

The invention provides a composite infiltrated layer as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out zinc impregnation treatment on a steel matrix by utilizing a zinc impregnation agent; and the steel matrix subjected to zinc impregnation treatment is subjected to swing laser melting treatment, and the abrasion-resistant and corrosion-resistant composite infiltrated layer is obtained. According to the method, laser melting with different swing tracks is carried out, so that the molten pool forms a vortex along the swing path of the laser, a more stable and uniform zincizing layer is formed on the surface of the zincizing steel and iron material, grains are further refined after remelting, and the hardness and wear resistance of the surface of the steel and iron material are improved.

The application discloses a long-afterglow nano carrier and a preparation method and application thereof, and belongs to the field of biomedical materials. The long-afterglow nano carrier comprises a near-infrared luminescent center, an organic mesoporous silica layer and an autophagy inhibitor; the organic mesoporous silica layer is coated on the outer layer of the near-infrared luminescent center, and the autophagy inhibitor is loaded in the mesopores of the organic mesoporous silica layer; the near-infrared luminescent center comprises a transition metal element; the organic mesoporous silica layer is prepared by co-condensation of an organic silane precursor and an inorganic silicon precursor, wherein the organic silane precursor is an organic silane containing a tetrasulfide bond, and the inorganic silicon precursor is a silicate compound. The carrier can specifically respond to excessively high concentration of hydrogen peroxide in a tumor microenvironment, and accurately release the loaded autophagy inhibitor; the release process can be observed by positioning with the aid of a high signal-to-noise ratio afterglow signal, thereby providing guidance for subsequent drug release, and finally realizing efficient radiotherapy sensitization.