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447 results about "Alimentary tracts" patented technology

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

Livestock feed proportioning method based on livestock growth

The invention discloses a livestock feed proportioning method based on livestock growth, and relates to the technical field of feed proportioning, and the livestock feed proportioning method comprises the following steps: collecting the body temperature and motion track data and environmental temperature and humidity data of livestock individuals, monitoring the concentration of amino acids in digestive tracts, preprocessing the collected data, and generating a standardized biological data set; analyzing the compensation amount of vitamins and trace elements according to the metabolic fingerprint spectrum, and constructing a multi-objective optimization function in combination with an individual growth curve; solving the multi-objective optimization function through a quantum annealing algorithm, and matching local raw material inventory data of block chain evidence storage to generate an optimization strategy; and executing the optimization strategy and detecting the mixing uniformity, and when the mixing uniformity index exceeds a preset mixing uniformity threshold, starting the compensation device to adjust the optimization strategy. According to the invention, through a cooperation mechanism of dynamic nutritional requirement identification and multi-constraint optimization, the precise regulation and control capability of livestock breeding is significantly improved.
Owner:ZHONGJI HI TECH (BEIJING) BIOTECHNOLOGY CO LTD

Angiotensin converting enzyme inhibitory peptide as well as screening method and application thereof

The invention belongs to the field of bioactive peptides. The invention provides an angiotensin converting enzyme inhibitory peptide as well as a screening method and application thereof. The amino acid sequence of the inhibitory peptide is GKGLW and / or GDGLKW. According to the screening method of the ACE inhibitory peptide, the soybean protein is taken as a raw material, and the ACE inhibitory peptide is prepared and screened by adopting a targeted alkaline protease and chymotrypsin double-enzymolysis technology, so that rapid screening of the ACE inhibitory peptide is realized, and an experimental basis is provided for the structure-function relationship of the ACE inhibitory peptide. The inhibitory peptide provided by the invention has strong antihypertensive activity, high safety and no toxic or side effect. Digestive tract stability determination shows that the inhibitory peptide has good gastrointestinal tract stability in gastrointestinal tract digestion, and can still keep good activity after entering blood.
Owner:EAST CHINA NORMAL UNIV

Fatty acid composition and application thereof in preparation of products for improving intestinal health

The invention relates to the technical field of feed products, in particular to a fatty acid composition and application thereof in preparation of products for improving intestinal health. The fatty acid composition comprises arachidonic acid, docosahexaenoic acid, eicosapentaenoic acid, butyric acid and lauric acid, or a precursor substance capable of releasing the fatty acid in the digestive tract, and the mass of the fatty acid composition is calculated according to the mass of the arachidonic acid, the mass of the docosahexaenoic acid, the mass of the eicosapentaenoic acid, the mass of the butyric acid and the mass of the lauric acid. The additive is prepared from the following components in parts by weight: 7-10 parts of arachidonic acid, 3-7 parts of docosahexaenoic acid, 3-7 parts of eicosapentaenoic acid, 2-5 parts of butyric acid and 1-3 parts of lauric acid. The composition can effectively relieve inflammation and diarrhea, regulate intestinal flora and improve intestinal health, and drug resistance is not prone to being generated.
Owner:CABIO BIOTECH (WUHAN) CO LTD +1

Fat-reducing nutritional composition capable of improving metabolism and preparation method of fat-reducing nutritional composition

The invention relates to the technical field of nutritional supplements. A traditional fat reducing method mainly comprises dieting, high-intensity exercise, medicine weight losing and the like. However, dieting may lead to malnutrition; high-intensity sports are difficult to insist, and sports injury is easily caused; in order to solve the technical problems, the invention discloses a fat-reducing nutritional composition capable of improving metabolism, and the fat-reducing nutritional composition can be used for solving the technical problems of severe side effects such as tachycardia, insomnia and the like caused by medicine weight loss. The composition comprises the following components in parts by weight: 13-21 parts of a bitter gourd extract, 15-31 parts of a garcinia cambogia extract, 13-17 parts of oat fibers, 17-23 parts of whey protein powder, 7-9 parts of linseed oil, 6-14 parts of a green tea extract, 9-15 parts of a calcium supplement and 15-19 parts of a purple perilla seed extract, and can provide energy for a user, supplement immune globulin, lactoferrin and a calcium source, improve the immunity of the user and improve the immunity of the user. The body metabolism level and immunocompetence are improved, absorption of fat in digestive tracts can be effectively inhibited, storage of fat in the body is reduced, fat consumption is promoted, and the fat reducing effect is achieved.
Owner:SHENYANG FOOD & SCULPTING INFORMATION CONSULTING SERVICE CO LTD

Animal combined lactobacillus D27 as well as screening method and application thereof

The invention discloses animal combined lactobacillus D27 as well as a screening method and application thereof, and relates to the technical field of microorganisms, and the key points of the technical scheme are as follows: the animal combined lactobacillus D27 is preserved in China General Microbiological Culture Collection Center (CGMCC) on May 9, 2024, and the preservation number is CGMCC No.30561. The animal combined lactobacillus D27 has the advantages that the animal combined lactobacillus D27 can be used for screening the animal combined lactobacillus D27; the animal combined lactobacillus D27 provided by the invention is a strain with excellent performance screened from the digestive tract of the calf, has the characteristics of stronger acid resistance, cholate resistance, strong adhesiveness, high lactic acid production and the like, and provides an excellent strain resource for the development of probiotics for preventing and treating calf diarrhea.
Owner:FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Visual digestive tract catheterization system integrating front-end driving and active steering

InactiveCN120899547ADomestic articlesFeeding-tubesGastrointestinal intubationEpiglottis
The invention discloses an integrated front-end driving, active steering and visual digestive tract catheterization system, which belongs to the field of medical apparatus and instruments, and comprises a guide arm comprising a pull wire and an elastic arm, the guide arm is provided with a first end and a second end deviating from each other, and one end of the pull wire is fixedly connected to the first end; the lens is arranged at the first end; the driving part comprises a first annular balloon, a second annular balloon and a cylindrical balloon, and the first annular balloon and the second annular balloon are fixedly connected to the two sides of the cylindrical balloon in the axial direction respectively; when the annular balloon is full, the outer wall expands in the radial direction; when the cylindrical balloon is full, the outer wall extends in the axial direction; the fixing sleeve comprises a flexible sleeve and a connecting base which are fixedly connected, the connecting base is connected with the second end of the guide arm and the first annular balloon, and the end, deviating from the connecting base, of the flexible sleeve penetrates through the driving part and extends in the direction deviating from the guide arm. Through the arrangement, the front end of the nasointestinal tube can be guided and driven at the epiglottis of the nasal cavity and the upper and lower digestive tracts.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Targeted drug delivery capsule robot based on soluble film

The invention discloses a targeted drug delivery capsule robot based on a soluble film. The targeted drug delivery capsule robot comprises a soft capsule shell, a magnetic control module, a camera module, a drug storage cavity, a release channel and the soluble film covering an outlet of the release channel. The capsule robot has the advantages that by means of the transparent design of the soft capsule shell, the intuition and safety of the drug delivery process are guaranteed, the targeted drug delivery mechanism is located at one end of the capsule robot, drug release is controlled by a soluble film, accurate response can be conducted according to the environmental conditions (such as pH value, temperature or enzyme concentration) of different parts of the digestive tract, and the targeted drug delivery mechanism is suitable for being applied to the digestive tract. Therefore, targeted release of the drug is realized. Due to the linkage design of the magnetic control system and the oscillation module, the capsule robot can be rapidly positioned to a target area in a complex alimentary canal environment, and the accuracy and reliability of targeted drug delivery are improved. Compared with a traditional medicine release mode, the structure remarkably reduces medicine waste and systemic side effects, and meanwhile the efficient treatment requirement of minimally invasive medical treatment is met.
Owner:CHINA UNIV OF MINING & TECH

Probiotic granules capable of improving intestinal functions as well as preparation method and application of probiotic granules

The invention belongs to the technical field of probiotic particles, and particularly relates to probiotic particles for improving intestinal functions as well as a preparation method and application of the probiotic particles. The probiotic particles capable of improving the intestinal function comprise a probiotic core, a first embedding layer, a second embedding layer and a third embedding layer, the probiotic inner core is prepared from plant lactobacillus, bifidobacterium animalis, lactobacillus acidophilus, bifidobacterium longum, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus fermentum, lactobacillus helveticus, streptococcus thermophilus, plant lactobacillus, lactobacillus helveticus and lactobacillus rhamnosus. According to the present invention, the twelve probiotics are contained, and the latest three-layer embedding technology is adopted so as to enhance the storage property and the digestive tract tolerance, such that the product can maintain the beneficial bacterium activity for a long time without refrigeration, and the product is suitable for the crowd with the alteration of the intestinal flora.
Owner:JIANG TENG MEDICAL SCI & TECH CO LTD

Isoquinoline drugs and their use in improving or treating gastrointestinal tumors

The present application relates to the technical field of small molecule drugs, in particular to a isoquinoline drug and its application in improving or treating digestive tract tumors, and aims to provide a compound, a pharmaceutical composition containing the compound and its application in treating colorectal cancer and gastric cancer, and provides a 3,13-position substituted berberine derivative, the drug itself has less toxicity and does not affect the growth of normal human cells, and has a good application prospect in the development of novel antitumor drugs, especially in the development of anti-digestive tract tumor drugs.
Owner:HEFEI JUNYIDA BIOMEDICAL TECHNOLOGY CO LTD

Follow-up visit management system for patients with inflammatory bowel diseases

The invention discloses a follow-up visit management system for an inflammatory bowel disease patient, and relates to the technical field of medical management. Comprising a patient management module which is in dynamic butt joint with a hospital information system, synchronizes patient data and endoscopic examination results in real time through an HL7 protocol, and establishes an electronic file containing an inflammatory bowel disease specificity tag; the diagnosis and treatment result module is used for storing structured data with temporal markers, including medication time sequences recorded by three groups of timestamps, administration routes and drug categories, auxiliary examination results accompanied with digestive tract pathological section images and hidden space feature vectors extracted from the images through a convolutional neural network; and the diet module is used for carrying out multi-level classification on diet photos uploaded by the patient through an image recognition unit based on MobileNetV3, and outputting food types and intake estimated values. According to the invention, by integrating the multi-dimensional data of the patient, the disease development trend is predicted, and personalized follow-up visit management is provided.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT-SEN UNIV GUANGXI HOSPITAL

Recombinant lactobacillus plantarum oral vaccine for preventing and controlling ASFV mucosal infection as well as preparation method and application of recombinant lactobacillus plantarum oral vaccine

The invention relates to the technical field of biological genetic engineering, in particular to construction of recombinant lactobacillus plantarum of an African swine fever virus antigen, and the method comprises the following steps: constructing a lactobacillus plantarum shuttle vector containing different ASFV antigen genes; and referring to a genome sequence of a Chinese isolate CADCHN09 of ASFV disclosed in GenBank. The method has the advantages that an inducer is not needed, antigen protein is efficiently expressed, the dendritic cell (DC) binding peptide for enhancing immune cell uptake and processing is subjected to fusion expression, the oral immunization mode is simple, mucosal immunity is stimulated, and ASFV infection is effectively prevented and controlled; probiotics, namely lactobacillus plantarum, which naturally exist in animal intestinal tracts and can be colonized and copied in digestive tracts for a long time are used as a carrier; key epitopes of proteins such as nucleocapsid protein p72, outer envelope protein CD2v, inner envelope protein p54, p22, pE199L and pE248R, which play an important role in adsorption, internalization, endocytosis and membrane fusion of ASFV, are preferably fused with dendritic cell binding peptide and then are displayed on the surface of lactobacillus plantarum.
Owner:HENAN TRILLION-ZHONGYUAN BIO-TECH CO LTD

Methods of treating eosinophilic esophagitis

PendingUS20250170057A1Organic active ingredientsAntipyreticUpper gastrointestinalEosinophil
The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and / or while the patient is lying down.
Owner:ELLODI PHARM LP

Method for measuring content of amino acid in chyme in digestive tract of livestock and poultry

The invention belongs to the technical field of detection methods, and provides a method for determining the content of amino acid in chyme in digestive tracts of livestock and poultry, which comprises the following steps: mixing a sample and a peroxyformic acid solution, and reacting to obtain an oxidation system; mixing the oxidation system, a hydrochloric acid solution and a chelating agent solution, and hydrolyzing to obtain a hydrolysis system; mixing the hydrolysis system and alkali liquor, then adjusting the pH value, and then mixing with acid liquor to obtain liquid to be detected; centrifuging the to-be-measured liquid, filtering, injecting a filtering system and the mixed amino acid standard liquid into an automatic amino acid analyzer, and measuring. According to the method, a certain amount of disodium ethylene diamine tetraacetate is added to chelate heavy metals in chyme in digestive tracts of livestock and poultry, and meanwhile, the heavy metals and redundant impurities are removed by adopting the steps of centrifuging, filtering and the like, so that the accuracy of amino acid detection is ensured, and the addicability of digestible amino acid content in daily ration is better. The hydrolysate is treated by adopting simple steps such as pH regulation and centrifugation, so that the operation process is simplified, and the operation error is reduced.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Application of pediococcus pentosaceus in preparation of products for improving pork quality and intestinal flora

PendingCN120188846ABacteriaAnimal feeding stuffBiotechnologyTibetan pig
The invention provides application of pediococcus pentosaceus in preparation of a product for improving pork quality and intestinal flora, and relates to the technical field of animal feeding. The pediococcus pentosaceus disclosed by the invention is pediococcus pentosaceus LL2018368, is separated from the digestive tract of a Diqing Tibetan pig and is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.18709. The pediococcus pentosaceus disclosed by the invention has the advantages that the pediococcus pentosaceus can be used for preparing the pediococcus pentosaceus; the pediococcus pentosaceus LL2018368 is added into drinking water of the Du-Si pigs, the influence of the pediococcus pentosaceus LL2018368 on archaea, meat quality, tissue fat-soluble vitamins and excrement metabolite composition in the excrement of the Du-Si pigs is studied, and the result shows that the pediococcus pentosaceus LL2018368 enables the species of the archaea in the excrement to tend to be consistent, so that the content of the archaea in the excrement of the Du-Si pigs in the excrement of the Du-Si pigs in the excrement of the Du-Si pigs is increased. The contents of vitamin A and all-trans-retinol in kidney tissues are increased, and the probiotic functions of amino acid and fat metabolism related bacteria and enzymes are improved.
Owner:YUNNAN ANIMAL SCI & VETERINARY INST

Extendable gastrointestinal stent and its use

The application provides an extendable digestive tract cannula and application thereof, and relates to the technical field of medical devices. The application comprises a first cannula, a second cannula and a degradable material. Opposite ends of the first cannula are a proximal end and a distal end, respectively. The first cannula is sleeved with the second cannula, and a double-layer structure is formed at the distal end of the first cannula. The double-layer structure is fixed by the degradable material. When the degradable material degrades, the second cannula moves towards the end face of the distal end of the first cannula. By setting the movable second cannula, the second cannula moves backward after the degradable material degrades, so that the length of the digestive tract cannula is extended. Since the length of the digestive tract cannula is increased, the area of intestinal absorption is also increased, the compensatory absorption function of the intestine at the distal end of the digestive tract cannula is weakened, the isolation effect of chyme and the intestine is improved, and the digestion and absorption effect of the intestine can be reduced for a long time.
Owner:HANGZHOU TANGJI MEDICAL TECH CO LTD

Lactobacillus salivarius and application thereof in regulating flora balance of digestive tract of mutton sheep

The invention relates to the technical field of probiotics, in particular to lactobacillus salivarius and application of the lactobacillus salivarius in regulating flora balance of digestive tracts of mutton sheep. The invention provides a lactobacillus salivarius KS1018, and the preservation number of the lactobacillus salivarius KS1018 is CCTCC (China Center for Type Culture Collection) NO: M 2025020. The lactobacillus salivarius KS1018 is a strain which is separated from dolang sheep rumen fluid and has the characteristics of high temperature resistance, acid resistance and cholate resistance, and has the advantages of low immunogenicity and high safety when being applied to mutton sheep. Due to the high-temperature-resistant characteristic, high stability can be kept in the feed mixing and processing process, and the application effect is further improved. The acid-resistant and cholate-resistant characteristics can reduce the influence of the digestive tract on the activity of the feed additive, so that the feed additive effectively plays a role in the digestive tract of the ruminant. The strain is good in palatability after being fed, and can effectively regulate digestive tract flora of ruminants, restore digestive tract flora balance and improve the disease-resistant potential of the ruminants.
Owner:CHINA AGRI UNIV

A nasogastric feeding device for digestive tract care with anti-reflux function

The present invention discloses a nasogastric feeding device for nursing the digestive tract with anti-backflow, which relates to the field of nasogastric feeding technology, including a feeding device and a hose, wherein the feeding device includes a driving rod and a housing, the upper and lower ends of the housing are respectively provided with end caps and a sleeve, a pressing plate and a mesh plate are installed inside the housing, a cavity is formed between the end cap and the sleeve, a four-way pipe is installed on the end cap, an air pump and a control valve are installed inside the four-way pipe, the pressing plate and the mesh plate are provided with a driving rod, and the four ports of the four-way pipe are respectively connected to the external environment, the cavity, the air pump and the space inside the housing. The present invention performs air extraction before food processing to prevent the liquid food from carrying a large amount of air into the patient's stomach during the infusion period, thereby preventing the patient from experiencing bloating. At the same time, the hose is provided with an anti-backflow mechanism to prevent the phenomenon of gastric fluid backflow due to the patient's body posture.
Owner:盐城市第三人民医院

Digestive tract tumor endoscopic image intelligent auxiliary diagnosis and grading system

The invention discloses an intelligent auxiliary diagnosis and grading system for gastrointestinal tumor endoscopic images, which belongs to the technical field of medical image processing and computer-aided diagnosis and comprises a multi-modal image preprocessing and segmentation module, a lesion feature extraction and diagnosis module, a grading and depth evaluation module and a closed-loop feedback optimization module. The system receives white light, a narrow band and an amplified endoscopic image, adaptive segmentation is performed to obtain a lesion area, mucous membrane morphology, capillary and gland features are extracted, Paris classification, Vienna classification and infiltration depth evaluation are realized, and segmentation parameters are subjected to closed-loop optimization according to classification confidence. And intelligent auxiliary support is provided for early diagnosis and treatment decision of gastrointestinal tumors.
Owner:JIANGSU CANCER HOSPITAL

Preparation method of enzyme preparation microcapsule with intestinal tract slow release function

The invention discloses a preparation method of an enzyme preparation microcapsule with an intestinal tract slow release function. According to the method, coating wall materials in a specific proportion are adopted, the coating wall materials comprise 10-12 parts of Arabic gum, 4-8 parts of gelatin, 3-6 parts of whey protein, 8-16 parts of beta-cyclodextrin and 5-10 parts of trehalose, the coating wall materials are mixed with 10-15 parts of an enzyme agent, and the enzyme preparation microcapsule is prepared through a spray drying technology. The enzyme preparation microcapsule has excellent thermal stability and gastric juice tolerance, can maintain more than 90% of enzyme activity under the condition of 90 DEG C, and still maintains more than 65% of enzyme activity after being treated in simulated gastric juice for 4 hours. In addition, the enzyme preparation microcapsule has an intestinal directional slow-release function, the enzyme activity is quickly released after entering the intestinal tract for 15 minutes, and the peak value is reached after the enzyme preparation microcapsule enters the intestinal tract for 60 minutes. The method effectively improves the stability and bioavailability of the enzyme preparation in feed processing and animal digestive tract environment, and has good application prospect and market value.
Owner:HUNAN MACKENWAY TECH CO LTD

Enhanced hydrogel composition, and preparation method therefor and use thereof

An enhanced hydrogel composition, and a preparation method therefor and the use thereof. According to the composition, a hydrogel is formed by means of a physical cross-linking mechanism using the chelation between calcium ions and an alginic acid raw material, with the assistance of a carboxymethyl cellulose raw material to reduce the sensitivity of the chelation. The hydrogel retains a high water absorption rate of media; meanwhile, the elastic modulus of the hydrogel is significantly enhanced by means of the introduction of silicon dioxide. The method for preparing the composition comprises: dispersing the carboxymethyl cellulose raw material, the alginic acid raw material, and the silicon dioxide in a solution, mixing same uniformly, drying the mixture to obtain a material A, and then mixing the material A with a calcium source to obtain the composition. Further provided is the use of the composition in the preparation of a space-occupying product in the digestive tract.
Owner:QINGDAO TANGJI SHUKANG TECHNOLOGY CO LTD

Super-resolution reconstruction method for optimizing alimentary canal air-barium double contrast radiography image

The invention relates to the technical field of medical image processing, in particular to a super-resolution reconstruction method for optimizing an alimentary canal air-barium double contrast contrast image. Comprising the following steps: acquiring a low-resolution image sequence of digestive tract air-barium double contrast radiography acquired by an image acquisition module; dynamically capturing a long-distance dependency relationship between position image elements in the low-resolution image sequence through a self-attention mechanism, and generating a feature representation reflecting context association between sequence images; based on the feature representation and local detail features in a single image in the low-resolution image sequence, generating a high-resolution image sequence containing more suspected focus detail information; and optimizing the details of the alimentary canal air-barium double contrast contrast image according to the high-resolution image sequence so as to assist in displaying the alimentary canal organ mucosa plica microstructure and the cavity form, thereby completing the super-resolution reconstruction of the alimentary canal air-barium double contrast contrast image optimization. The method obviously improves the image quality of digestive tract air-barium double contrast radiography.
Owner:TIANJIN FUXUN TECH DEV CO LTD

Gastrointestinal endoscopy specimen collection device

The present invention discloses a digestive tract endoscope specimen collection device, comprising a catheter, a collecting tube provided at one end of the catheter, a shearing assembly provided in the collecting tube, the shearing assembly comprising a fixing groove provided on the inner side of one end of the collecting tube, a rotating card provided with an internal meshing gear in the fixing groove, a plurality of fixing columns evenly provided at one end of the collecting tube, a rotating card provided with a gear on the fixing column, a shearing knife connected to the outer side of the gear, the internal meshing gear meshing with all the gears at the same time, the catheter being connected to the internal meshing gear through a control assembly, and a clamping assembly provided in the collecting tube; the shearing assembly provided in the present invention can seal and store the specimen while the device is cutting and collecting the specimen, and the first traction rope is pulled outward, at this time the first traction rope will pull outward the control board connected to its free end, so that the shearing knife will jointly shear the specimen, and when the shearing is completed, the specimen will be directly stored in the collecting tube, and at this time the clamping assembly can be driven to clamp the specimen and take it out.
Owner:中国人民解放军总医院第八医学中心

Natto peptide sea cucumber polysaccharide lipidosome capable of synergistically improving cardiovascular health and preparation method and application of natto peptide sea cucumber polysaccharide lipidosome

The invention discloses a natto peptide sea cucumber polysaccharide liposome for synergistically improving cardiovascular health and a preparation method and application thereof, belongs to the field of active peptide delivery systems, and aims to solve the stability problem of natto oligopeptide in gastrointestinal digestive tracts. The phytosterol and the vitamin E are filled between phospholipid double layers of the liposome to support a gap between the phospholipid double layers, and the ratio of the phytosterol to the vitamin E is (1-3): 1, so that the natto oligopeptide liposome has the effects that the storage of the natto oligopeptide and the stability of the natto oligopeptide in gastrointestinal and digestive tracts can be improved, the bioavailability of the natto oligopeptide liposome is improved, and the bioavailability of the natto oligopeptide liposome is improved. The traditional Chinese medicine composition has synergistic effects in the aspects of anticoagulation, thrombolysis and blood fat reduction, and has a good cardiovascular protection effect.
Owner:DALIAN SHENLAN PEPTIDE TECH R & D CO LTD

Proteus mirabilis bacteriophage PF05, and bacteriophage composition and application thereof

The invention belongs to the technical field of bacteriophages, and discloses a proteus mirabilis bacteriophage PF05, a bacteriophage composition thereof and application of the proteus mirabilis bacteriophage PF05, the proteus mirabilis bacteriophage PF05 is preserved in China General Microbiological Culture Collection Center (CGMCC) on March 22, 2024, the preservation address is No. 3, No.1 yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC NO.9687. The preservation number is CGMCC (China General Microbiological Culture Collection Center) The bacteriophage is resistant to high temperature, wide in lysis spectrum, high in storage stability and good in gastric acid tolerance, can keep activity in the stomach for a long time, and has a good prevention and treatment effect on infection of proteus mirabilis in the intestines and the stomach. The compound can be prepared into medicines, environment disinfectants, feeds, water additives and the like for preventing and treating proteus mirabilis for application, not only effectively prevents and treats propagation of proteus mirabilis, but also has the effects of reducing the death rate of chicken flocks, reducing digestive tract infection of the chicken flocks, avoiding diarrhea of the chicken flocks and improving the resistance of the chicken flocks, and has a very good market application prospect.
Owner:QINGDAO PHAGEPHARM BIO TECH CO LTD

Breath analyzer devices and breath test methods

The present invention provides an improved breath analyzer and breath test method to determine the presence of disease in humans, including but not limited to, the bacterium H. pylori in a subjects digestive tract. In certain embodiments, the present invention provides a universal breath testing platform and methods of testing for diseases of the gastrointestinal tract, the liver, the kidneys, and the lungs, along with testing for cancer, infections, and metabolic diseases.
Owner:RIGAS ANASTASIA

Interventional therapy device for gastrointestinal hemorrhage

InactiveCN120284374AWound clampsGastrointestinal bleedingOuter Cannula
The invention is applicable to the technical field of medical instruments, and provides an interventional therapy device for alimentary canal hemorrhage, which comprises an outer sleeve and a guide wire arranged in the outer sleeve, and further comprises a plurality of hemostatic clips, each hemostatic clip comprises a cylindrical body, a ball head is fixed at one end of each cylindrical body, and the other end of each cylindrical body is rotatably connected with two clamping jaws; a guide cavity is formed in the cylindrical body in the length direction, a guide block is slidably connected into the guide cavity, a tension spring is fixed to the end, close to the ball head, of the guide block, and the tail end of the tension spring is fixed into the guide cavity; when a plurality of hemostatic clips are sequentially connected end to end, the two clamping jaws on one hemostatic clip clamp the ball head on the adjacent hemostatic clip, so that the two adjacent hemostatic clips are in ball joint. A plurality of hemostatic clips can be placed in the outer sleeve at a time, a plurality of hemostatic clips can be used in sequence, the outer sleeve and the guide wire do not need to be repeatedly pulled out from a biopsy duct of an endoscope during use, then the surgical efficiency is improved, and surgical operation steps are simplified.
Owner:JINGGANGSHAN UNIV AFFILIATED HOSPITAL

A foreign body extraction device for digestive internal medicine and a manufacturing method thereof

The present application relates to gastrointestinal endoscope accessory technical field, specifically provide a kind of foreign body extraction device for gastroenterology and its manufacturing method, device includes main air pipe and respectively communicated at both ends of main air pipe air bag cup and positive and negative pressure air pump;Air bag cup includes air bag cup framework and membrane structure;Air bag cup framework includes cup body, cup mouth air bag, support air bag, clamping air bag;The upper end of cup body is provided with suction port, and the lower end is communicated with main air pipe, and at least two opposite ends of cup body are provided with inflation port respectively;Suction port is provided with negative pressure valve, and inflation port is provided with positive pressure valve;Support air bag is supported between cup mouth air bag and cup body, and the inside of support air bag located in membrane structure is communicated with clamping air bag.The way of foreign body extraction gastrointestinal tract by negative pressure adsorption, compared with traditional jaw structure, without considering the gap between foreign body and gastrointestinal wall, without adjusting angle or orientation, with the characteristics of high operating efficiency, convenient operation.
Owner:JINGZHOU SECOND PEOPLES HOSPITAL

Digestive endoscopy report generation method and device based on multi-modal large language model

The invention relates to the technical field of computer vision and medical image processing, and discloses a digestive endoscopy report generation method and device based on a multi-modal large language model. The method specifically comprises the following steps: for a plurality of upper gastrointestinal endoscopy images, extracting a first image feature through a visual encoder to perform anatomical part identification; extracting a second image feature from the first image feature by using a self-attention mechanism to perform background gastric mucosa classification; generating description about digestive tract diseases through a large language model, and under the guidance of the description, extracting third image features from the first image features to perform digestive tract disease classification; the constructed text instruction about report generation and the third image feature are combined and then input into a multi-mode decoder, and a digestive endoscopy report is generated. According to the method, a plurality of upper gastrointestinal endoscopy image analysis tasks can be processed at the same time, and a digestive endoscopy report which does not depend on a fixed template and has rich context content can be generated with high efficiency and high accuracy.
Owner:TONGJI UNIV +1

Digestive tract drug delivery system

The invention relates to the technical field of medical devices, in particular to a digestive tract drug delivery system which comprises an intervention module, a drug delivery module and a drug delivery module. Comprising a closing unit and a dosing unit; the parameter acquisition module consists of a first image acquisition unit and a second image acquisition unit which are used for acquiring an image of a point to be applied with medicine, and a third image acquisition unit which is used for acquiring an ultrasonic image of the point to be applied with medicine; and the drug administration control module is used for determining that the operation mode of the drug administration module is a closed mode or a non-closed mode and preliminarily judging whether the closing of the closing unit meets a preset standard according to a closing characteristic value. According to the invention, the precision and safety of administration are improved.
Owner:CHIFENG COLLEGE AFFILIATED HOSPITAL

Preparation and application of phytobacterium plantarum DPUL-Y42 microcapsule and coated microcapsule

The invention discloses preparation and application of a phytobacterium plantarum DPUL-Y42 microcapsule and a coated microcapsule, and belongs to the technical field of microorganisms. The preparation method comprises the following steps: embedding probiotic plant lactobacillus DPUL-Y42 into wall materials of sodium alginate or sodium alginate and chitosan by utilizing a microcapsule technology to prepare a microcapsule, and culturing to prepare a coated microcapsule; the survival rate of the plant lactobacillus DPUL-Y42 in the plant lactobacillus DPUL-Y42 microcapsule and the plant lactobacillus DPUL-Y42 envelope state microcapsule in acid solutions with different pH values, simulated gastric juice, simulated intestinal juice, different temperature conditions and freeze-drying conditions is obviously improved, the resistance of thalli to the digestive tract environment can be effectively enhanced, and the thalli are released at a proper position, so that the survival rate of the plant lactobacillus DPUL-Y42 in the plant lactobacillus DPUL-Y42 microcapsule and the plant lactobacillus DPUL-Y42 envelope state microcapsule is improved. And the probiotic effect is exerted.
Owner:DALIAN POLYTECHNIC UNIVERSITY