Airway and esophagus reflux protection monitoring system based on fluorescence imaging

Abstract

The invention relates to the technical field of medical instruments, and discloses an airway and esophagus reflux protection monitoring system based on fluorescence imaging. The existing non-invasive monitoring method has the problems that equipment wearing is unstable, a light window is easy to pollute and the like, so that the monitoring accuracy is influenced. The system comprises an in-vitro imaging module, a fluorescent diaphragm and a necklace. The in-vitro imaging module is worn on the anterior neck of a patient to detect a fluorescence signal; the fluorescent diaphragm is swallowed by a patient, consists of a pepsin response layer and a pH sensitive indication layer, and can emit a fluorescent signal according to the pH value change of gastric juice; the air bag is arranged in the elastic band of the necklace, the connecting base can stably abut against the lower portion of the laryngeal knot after inflation, and the cleaning assembly is arranged on the connecting base and can automatically clean an in-vitro imaging module light window. The system realizes efficient and accurate monitoring of airway and esophageal reflux, provides a reliable basis for clinical diagnosis, and is suitable for monitoring airway and esophageal reflux conditions.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an airway-esophageal reflux protection monitoring system based on fluorescence imaging. Background Art

[0002] In the medical field, airway esophageal reflux is a common pathological phenomenon that can lead to a series of serious health problems, such as aspiration pneumonia, chronic cough, and asthma. Accurate monitoring of airway esophageal reflux is important for early diagnosis of the disease, formulation of treatment plans, and assessment of patient prognosis.

[0003] Currently, clinical monitoring of airway-esophageal reflux mainly relies on invasive or non-invasive methods. Invasive methods, such as esophageal pH monitoring, can provide relatively accurate reflux data, but require patients to wear a catheter for a long time, causing great discomfort to patients and potentially causing complications such as infection and bleeding. Non-invasive methods, such as multi-channel intraluminal impedance-pH monitoring, although reducing patient pain, are complex in equipment, cumbersome in operation, and high in cost, limiting their widespread clinical application.

[0004] Furthermore, existing non-invasive monitoring methods often make it difficult to maintain a stable and comfortable fit during the monitoring process. This can affect monitoring data due to factors such as changes in patient position and device displacement, thereby reducing monitoring accuracy. Furthermore, key components such as the optical window of monitoring equipment are susceptible to contamination during long-term use, affecting monitoring effectiveness. Existing cleaning methods often require manual labor, which is not only inefficient but also difficult to ensure thorough cleaning. Summary of the Invention

[0005] The purpose of the present invention is to solve the shortcomings of the existing non-invasive monitoring methods in the prior art, which often make it difficult to wear the monitoring equipment stably and comfortably during the monitoring process, resulting in the monitoring data being affected by factors such as changes in patient position and equipment displacement, thereby reducing the accuracy of monitoring. A fluorescence imaging-based airway and esophageal reflux protection monitoring system is proposed.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions:

[0007] An airway-esophageal reflux protection monitoring system based on fluorescence imaging, comprising:

[0008] an external imaging module configured to be worn on the front of the patient's neck and detect fluorescent signals;

[0009] A fluorescent membrane, swallowed by a patient, comprises a pepsin-responsive layer and a pH-sensitive indicator layer disposed on the outer wall of the pepsin-responsive layer, wherein the pH-sensitive indicator layer emits a fluorescent signal in response to changes in the pH value of gastric fluid, and the pepsin-responsive layer dissolves under the action of pepsin to release the pH-sensitive indicator layer;

[0010] The collar includes a connecting base and an elastic band, one end of the elastic band being fixedly connected to one side of the connecting base and the other end being detachably plugged into the connecting base. The elastic band is provided with an air bag connected to an inflatable ball via a pipe. The air bag is configured to be inflated to firmly press the connecting base below the patient's Adam's apple.

[0011] In which, the in vitro imaging module is detachably arranged on one side of the connecting seat, and the connecting seat is provided with a positioning hole corresponding to the light window of the in vitro imaging module. The connecting seat is also provided with a cleaning component. When the in vitro imaging module is installed, the cleaning component is used to automatically clean the light window to ensure accurate reception of the fluorescent signal.

[0012] As a further improvement of the above technical solution:

[0013] The cleaning assembly includes a accommodating cavity opened on one side of the connecting seat, a side panel detachably arranged on one side of the accommodating cavity, and a mounting seat integrally formed on one side of the side panel. The mounting seat is provided with two rotating shafts that rotate through bearings, one of which is fixed with and wrapped with a cleaning cloth, and the other end of the cleaning cloth is fixedly connected to the other rotating shaft. The rotating shaft located above cooperates with one end of the elastic band to drive the rotating shaft to rotate and rewind the cleaning cloth during the insertion of the elastic band, thereby realizing the movement of the cleaning cloth.

[0014] A positioning block is integrally formed on the outer side of the side plate, and the other end of the elastic band is fixedly connected with an inserting block which is plugged into the positioning block.

[0015] One end of the rotating shaft located above extends into the positioning block and is provided with a gear through a one-way bearing sleeve. A rack engaged with the gear is fixed on one side of the insert block to drive the gear to rotate when the insert block is inserted into the positioning block, thereby driving the rotating shaft to reel in the cleaning cloth.

[0016] Four mounting holes are provided on one side of the connecting seat, and a sliding column is slidably arranged in the mounting hole. A spring is provided on the outer wall of the sliding column. The two ends of the spring respectively contact the connecting seat and the sliding column. The outer ends of the corresponding two sliding columns are fixedly connected to the same connecting strip, which is plugged into the in vitro imaging module.

[0017] Insertion strips are welded on both sides of the in vitro imaging module. Sleeve rods are inserted into the outer walls of the insertion strips. The two sleeve rods are welded to the two connecting strips respectively.

[0018] The two connecting strips are each provided with a protrusion on one side away from each other, and the protrusion is configured to facilitate manual pulling to disassemble the in vitro imaging module.

[0019] The inner ring of the airbag is connected to a breathable plate through a plurality of support bars. The breathable plate is configured to firmly press against the neck when the airbag is inflated and provide breathability.

[0020] The pepsin response layer of the fluorescent membrane is made of a polyfluorene-NDI complex, and the pH-sensitive indicator layer contains bromocresol purple dye. The pepsin response layer degrades within 30 minutes when the pepsin concentration is greater than 0.5 mg / mL, releasing 1050-1350 nm near-infrared fluorescence.

[0021] The in vitro imaging module includes a dual-band NIR light source, a NIR-II CMOS sensor, an optical filtering system, a microprocessor, a wireless transmission module and a battery. The dual-band NIR light source is configured to emit 850nm and 1300nm light, and the NIR-II CMOS sensor has a response band of 1000-1700nm, which is used to capture and analyze fluorescence signals in real time to monitor reflux.

[0022] Beneficial effects:

[0023] In the present invention, the airway esophageal reflux protection monitoring system based on fluorescence imaging utilizes the pH-sensitive indicator layer of the fluorescent diaphragm to emit a fluorescent signal of a specific wavelength according to the pH value change of the gastric juice. The design of the pepsin response layer ensures the stable presence of the fluorescent diaphragm in the stomach, and gradually dissolves to release the pH-sensitive indicator layer, thereby ensuring the accuracy and durability of the fluorescent signal. The in vitro imaging module can accurately reflect the airway esophageal reflux situation in real time by accurately detecting these fluorescent signals, providing doctors with a reliable diagnostic basis;

[0024] In the present invention, the airway-esophageal reflux protection monitoring system based on fluorescence imaging has a collar that adopts a combined design of an elastic band and a connecting seat. The airbag in the elastic band is inflated by an inflatable ball, which can firmly fix the connecting seat below the patient's Adam's apple. This not only ensures the stable wearing of the external imaging module, but also improves the patient's wearing comfort through the elastic cushioning effect of the airbag. At the same time, the design of the breathable plate and support strip further enhances the stability and breathability of the airbag, ensuring comfort for long-term wearing.

[0025] In the present invention, the airway-esophageal reflux protection and monitoring system based on fluorescence imaging uses a cleaning component to drive the rotation of the rotating shaft by the plugging action of the elastic band during the installation of the external imaging module, thereby achieving automatic cleaning of the light window, avoiding the tediousness and uncertainty of manual cleaning, ensuring the cleanliness of the light window, and further guaranteeing the accurate reception and monitoring quality of the fluorescence signal;

[0026] In the present invention, the airway esophageal reflux protection monitoring system based on fluorescence imaging is characterized in that the external imaging module is connected to the connecting strip on the connecting seat by plugging the insert and the sleeve rod, thereby achieving fast and convenient installation and removal. At the same time, the protrusion design on the connecting strip facilitates the patient or medical staff to remove the external imaging module by pulling the protrusion, further improving the ease of use of the system.

[0027] In the present invention, by integrating a fluorescent diaphragm and an extracorporeal imaging module, combined with an adjustable collar design and an automated cleaning component, efficient and accurate monitoring of airway esophageal reflux is achieved. The fluorescent diaphragm can emit fluorescent signals in response to changes in the gastric environment, and the extracorporeal imaging module captures and analyzes these signals in real time, providing a reliable basis for clinical diagnosis. The elastic band and airbag design of the collar ensure the stable wearing and comfort of the monitoring equipment, and the introduction of the cleaning component effectively avoids light window contamination and ensures the accuracy of the monitoring data. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 This is a schematic structural diagram of the use process of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0029] Figure 2 This is a schematic diagram of the fluorescent diaphragm structure of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0030] Figure 3 This is a schematic diagram of the in vitro imaging module and collar installation structure of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0031] Figure 4 This is a partial cross-sectional structural diagram of a connector of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0032] Figure 5 This is a schematic structural diagram of an in vitro imaging module of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed in the present invention;

[0033] Figure 6 This is a schematic diagram of the side panels and winding roller structure of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0034] Figure 7 This is a schematic diagram of the winding roller structure of the airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed by the present invention;

[0035] Figure 8 This is a schematic diagram of the partial cross-sectional structure of a collar of an airway-esophageal reflux protection monitoring system based on fluorescence imaging proposed in the present invention.

[0036] In the figure: 1. collar; 2. in vitro imaging module; 200. light window; 3. fluorescent diaphragm; 300. pH-sensitive indicator layer; 301. pepsin response layer; 4. inflatable ball; 10. connecting seat; 11. elastic band; 12. air bag; 13. breathable plate; 14. cleaning cloth; 15. mounting hole; 16. sliding column; 17. spring; 18. connecting strip; 19. protrusion; 20. positioning hole; 21. insert; 22. sleeve rod; 23. accommodating cavity; 24. side panel; 25. positioning block; 26. mounting seat; 27. rotating shaft; 28. gear; 29. insert; 30. rack; 31. support bar. DETAILED DESCRIPTION

[0037] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0038] In one embodiment: refer to Figures 1-8 A monitoring system includes: an in vitro imaging module 2, a fluorescent membrane 3, and a collar 1.

[0039] The in vitro imaging module 2 is worn on the front of the patient's neck through the collar 1 to detect the fluorescence emitted by the fluorescent membrane 3 swallowed by the patient. The fluorescent membrane 3 is a double-layer structure:

[0040] Pepsin-responsive layer 301: 50 μm thick, made of polyfluorene-NDI complex. When exposed to pepsin (concentration > 0.5 mg / mL), it degrades within 30 minutes and releases near-infrared fluorescence at 1050-1350 nm.

[0041] pH sensitive indicator layer 300: Coated on the outer wall of response layer 301, containing bromocresol purple dye (thickness 20 μm). It turns yellow when pH < 5.0 and purple when pH > 6.8, used to indicate that the membrane has entered the duodenum.

[0042] Physical parameters: 5mm diameter, bendability >150°, ISO 10993 biocompatibility certified.

[0043] When the fluorescent membrane 3 enters the stomach, the pH sensitive indicator layer 300 will emit fluorescence of a specific wavelength according to the pH value of the gastric juice, and the pepsin response layer 301 is used to gradually dissolve under the action of pepsin, releasing the pH sensitive indicator layer 300, ensuring the accuracy and durability of the fluorescent signal.

[0044] The collar 1 consists of an elastic band 11 and a connector 10. One end of the elastic band 11 is fixedly connected to one side of the connector 10, while the other end plugs into the connector 10 via a connector, making it easy for the patient to wear and adjust the tightness. An airbag 12 is located within the elastic band 11, connected to an inflatable ball 4 via a tube. During wear, the patient presses the inflatable ball 4 to inflate the airbag 12, thereby firmly securing the connector 10 below the Adam's apple and preventing the external imaging module 2 from moving or falling off.

[0045] The external imaging module 2 is detachably mounted on one side of the connector 10. A positioning hole 20 corresponding to the light window 200 is provided on one side of the connector 10 to ensure that the light window 200 of the external imaging module 2 can be accurately aligned with the patient's neck area to receive the fluorescent signal emitted by the fluorescent diaphragm 3.

[0046] The in vitro imaging module 2 includes the following core components:

[0047] Dual-band NIR light source: 850nm LED (10mW / cm 2 )+1300nm VCSEL laser (5mW / cm 2 ), pulse modulation (1kHz);

[0048] NIR-IICMOS sensor: InGaAs array (640×512 pixels), response band 1000-1700nm, quantum efficiency >80% @1300nm;

[0049] Optical filtering system: bandpass filter (1050-1600nm) to suppress background light interference;

[0050] Microprocessor: ARM Cortex-M7+FPGA, real-time image processing capability;

[0051] Wireless transmission: BLE 5.0+Wi-Fi 6, supporting 1080p@30fps streaming transmission;

[0052] Battery: solid-state lithium battery (3.7V / 800mAh), battery life ≥8 hours;

[0053] Shell: medical-grade titanium alloy (weight <40g), curved to fit the front of the neck;

[0054] Optical window: Sapphire glass lens, transmittance >95%@1000-1600nm.

[0055] A cleaning assembly for use with the in-vitro imaging module 2 is also provided on one side of the connector 10. The cleaning assembly includes a receiving cavity 23 formed on one side of the connector 10. A side panel 24 is connected to the receiving cavity 23 via magnets or bolts. A mounting seat 26 is integrally formed on one side of the side panel 24, plugging into the receiving cavity 23. Two rotating shafts 27 are rotatably mounted on one side of the mounting seat 26 via bearings. A cleaning cloth 14 is secured to and wound around one of the rotating shafts 27. The other end of the cleaning cloth 14 is fixedly connected to the other rotating shaft 27.

[0056] This application can be used in the field of medical devices, and can also be used in other fields applicable to this application.

[0057] In another embodiment: Figures 1-8 , an airway esophageal reflux protection monitoring system based on fluorescence imaging, which is applied to the field of medical devices. The inner circle of the airbag 12 is connected to the air permeable plate 13 through multiple support bars 31. The design of the air permeable plate 13 not only ensures the stability of the airbag 12, but also allows air circulation, thereby improving the patient's wearing comfort.

[0058] During the installation of the in vitro imaging module 2, the other end of the elastic band 11 is fixedly connected to an insert block 29 that plugs into the positioning block 25. One end of the rotating shaft 27 located above extends into the positioning block 25 and is provided with a gear 28 through a one-way bearing sleeve. A rack 30 that cooperates with the gear 28 is fixedly provided on one side of the insert block 29. When the elastic band 11 is plugged in, the rack 30 engages with the gear 28, driving the rotating shaft 27 to rotate, thereby driving the cleaning cloth 14 to move and clean the light window 200, ensuring accurate reception of the fluorescent signal. The rotating shaft 27 will not be driven to rotate during the removal of the insert block 29. At the same time, there is resistance between the rotating shaft 27 and the mounting seat 26, and it will not rotate in the absence of external force.

[0059] One side of the connector 10 has four mounting holes 15, within which slide posts 16 slide. Springs 17 are sheathed around the outer walls of the slide posts 16. The ends of the springs 17, through the connector 10, respectively, contact the inner wall of one side of the mounting holes 15 and one end of the slide posts 16. A connecting bar 18, which plugs into the in-vitro imaging module 2, is fixed to the outer ends of two corresponding slide posts 16.

[0060] Inserts 21 are welded to both sides of the in-vitro imaging module 2, and sleeve rods 22 are inserted into the outer walls of the inserts 21. The two sleeve rods 22 are welded to the two connecting bars 18, respectively. When installing the in-vitro imaging module 2, the inserts 21 are inserted into the sleeve rods 22. Simultaneously, the connecting bars 18 retract inward under the action of the springs 17, firmly securing the in-vitro imaging module 2 to the connecting base 10. Both connecting bars 18 have protrusions 19 on their sides facing away from each other, making it easier for patients or medical personnel to remove the in-vitro imaging module 2 by pressing on the protrusions 19.

[0061] During use, the patient swallows the fluorescent membrane 3. When the fluorescent membrane 3 enters the esophagus, the outer side of the pH sensitive indicator layer 300 will adhere to the inner wall of the esophagus.

[0062] Place the connecting base 10 on the cricoid cartilage below the Adam's apple, pass the elastic band 11 around the back of the neck, and insert the insert block 29 into the positioning block 25. During the insertion process, the rack 30 can be used to drive the gear 28 to rotate, which can drive the upper rotating shaft 27 to rotate and rewind the cleaning cloth 14, so that the unused cleaning cloth 14 moves to the side of the mounting base 26.

[0063] Then press the inflation ball 4 to inflate the airbag 12, so that the airbag 12 expands, which can make the air permeable plate 13 contact the neck and fix the connecting seat 10;

[0064] Then pull the two protrusions 19 outward. The movement of the protrusions 19 can drive the connecting strip 18 to move outward and drive the sliding column 16 to compress the spring 17. Place the in vitro imaging module 2 on one side of the connecting seat 10 so that the insertion strip 21 corresponds to the sleeve rod 22, and then insert the insertion strip 21 into the sleeve rod 22. At this time, the light window 200 will rub against the cleaning cloth 14. Use the cleaning cloth 14 to clean the light window 200. After insertion, the light window 200 corresponds to the positioning hole 20. Release the two protrusions 19. The sliding column 16 can reset and move under the action of the spring 17, and drive the connecting strip 18 closer to the connecting seat 10, so that the insertion strip 21 and the sleeve rod 22 can be used to drive the in vitro imaging module 2 closer to the connecting seat 10, and fix the in vitro imaging module 2 on one side of the connecting seat 10. At this time, the installation is completed.

[0065] The drawings in this application are for illustrative purposes only. The sizes and shapes of the components shown are not intended to be limiting, but are merely for illustrative purposes. In actual implementation, the components may be appropriately configured and adjusted based on specific needs and actual conditions.

[0066] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

Claims

1. An airway-esophageal reflux protection monitoring system based on fluorescence imaging, characterized in that: include: an external imaging module (2) configured to be worn on the front of the patient's neck and detect fluorescent signals; A fluorescent membrane (3) is swallowed by a patient and comprises a pepsin-responsive layer (301) and a pH-sensitive indicator layer (300) disposed on the outer wall of the pepsin-responsive layer (301), wherein the pH-sensitive indicator layer (300) emits a fluorescent signal in response to a change in the pH value of gastric fluid, and the pepsin-responsive layer (301) dissolves under the action of pepsin to release the pH-sensitive indicator layer (300); A collar (1) comprises a connecting seat (10) and an elastic band (11), one end of the elastic band (11) being fixedly connected to one side of the connecting seat (10), and the other end being detachably plugged into the connecting seat (10), an air bag (12) being provided in the elastic band (11), the air bag (12) being connected to an inflatable ball (4) via a pipe, and the air bag (12) being configured to press the connecting seat (10) firmly against the lower part of the patient's Adam's apple by inflating; The in vitro imaging module (2) is detachably arranged on one side of the connecting seat (10), the connecting seat (10) is provided with a positioning hole (20) corresponding to the light window (200) of the in vitro imaging module (2), and the connecting seat (10) is further provided with a cleaning component, and when the in vitro imaging module (2) is installed, the cleaning component is used to automatically clean the light window (200) to ensure accurate reception of the fluorescent signal.

2. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 1, characterized in that: The cleaning assembly comprises an accommodating cavity (23) provided on one side of the connecting seat (10), a side plate (24) detachably provided on one side of the accommodating cavity (23), and a mounting seat (26) integrally formed on one side of the side plate (24). The mounting seat (26) is provided with two rotating shafts (27) rotatably through bearings, a cleaning cloth (14) is fixed on and wound around one of the rotating shafts (27), and the other end of the cleaning cloth (14) is fixedly connected to the other rotating shaft (27). The rotating shaft (27) located above cooperates with one end of the elastic band (11) to drive the rotating shaft (27) to rotate and reel in the cleaning cloth (14) during the insertion process of the elastic band (11), thereby realizing the movement of the cleaning cloth (14).

3. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 2, characterized in that: A positioning block (25) is integrally formed on the outer side of the side plate (24), and the other end of the elastic band (11) is fixedly connected with an inserting block (29) inserted into the positioning block (25).

4. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 3, characterized in that: One end of the rotating shaft (27) located above extends into the positioning block (25) and is provided with a gear (28) through a one-way bearing sleeve. A rack (30) meshing with the gear (28) is fixedly provided on one side of the insert block (29) so that the gear (28) is driven to rotate when the insert block (29) is inserted into the positioning block (25), thereby driving the rotating shaft (27) to reel in the cleaning cloth (14).

5. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 1, characterized in that: One side of the connecting seat (10) is provided with four mounting holes (15), a sliding post (16) is slidably provided in the mounting hole (15), an outer wall of the sliding post (16) is provided with a spring (17), two ends of the spring (17) respectively contact the connecting seat (10) and the sliding post (16), and the outer ends of the corresponding two sliding posts (16) are fixedly connected to the same connecting bar (18), and the connecting bar (18) is plugged into the in vitro imaging module (2).

6. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 5, characterized in that: Insertion strips (21) are welded to both sides of the in vitro imaging module (2), sleeve rods (22) are inserted into the outer walls of the insertion strips (21), and the two sleeve rods (22) are welded to the two connecting strips (18) respectively.

7. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 5, characterized in that: The two connecting strips (18) are both provided with protrusions (19) on the sides away from each other. The protrusions (19) are configured to facilitate manual pulling to disassemble the external imaging module (2).

8. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 1, characterized in that: The inner ring of the airbag (12) is connected to a breathable plate (13) through a plurality of support bars (31). The breathable plate (13) is configured to firmly press against the neck when the airbag (12) is expanded and provide breathability.

9. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to any one of claims 1-8, characterized in that: The pepsin response layer (301) of the fluorescent membrane (3) is made of a polyfluorene-NDI complex, and the pH sensitive indicator layer (300) contains bromocresol purple dye, wherein the pepsin response layer (301) degrades within 30 minutes when the pepsin concentration is greater than 0.5 mg / mL, releasing 1050-1350 nm near-infrared fluorescence.

10. The airway-esophageal reflux protection monitoring system based on fluorescence imaging according to claim 1, characterized in that: The in vitro imaging module (2) includes a dual-band NIR light source, a NIR-II CMOS sensor, an optical filtering system, a microprocessor, a wireless transmission module and a battery, wherein the dual-band NIR light source is configured to emit 850nm and 1300nm light, and the NIR-II CMOS sensor has a response band of 1000-1700nm, and is used to capture and analyze fluorescence signals in real time to monitor reflux conditions.

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