The invention discloses blueberry bubbling freshening sugar for relieving vision fatigue and a preparation method of the blueberry bubbling freshening sugar, and relates to the technical field of freshening sugar and processing of the freshening sugar. The freshening sugar is prepared from the following components in parts by weight: 27-35 parts of resistant dextrin, 1-3 parts of lutein ester, 3-7parts of blueberry extract, 20-30 parts of maltitol, 0.5-1.5 parts of tartaric acid, 0.1-0.4 parts of sodium bicarbonate, 0.5-1 part of magnesium stearate, 0.3-0.7 parts of aspartame, 0.2-1 part of sucralose, 0.5-1 part of beta-carotene, 0.1-0.5 parts of fruit flavor and 0.1-0.6 parts of traditional Chinese medicine additives. The freshening sugar keep bubbling in the mouth and bring tactile stimulation, and the consumption experience of the freshening sugar is improved; the added blueberry extract contains rich anthocyanin which can protect vision, relieve vision fatigue symptoms such as blurred vision, dry eyes and eye swelling together with lutein ester; the traditional Chinese medicine additives are synergistic with beta-carotene and the like, vision fatigue, dry eyes and the like canbe effectively relieved for people with excessive eye use, and accordingly, additional value of the freshening sugar is increased on the basis of breath freshening.