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Method for extracting multiple active nutrient contents from sea cucumber processing liquid and application of method

A technology of nutritional ingredients and processing fluids, which is applied in the field of orally disintegrating tablets, can solve the problems of inability to cause, bad taste and flavor, etc., and achieve the effects of less damage, easy absorption, and mild reaction conditions

Active Publication Date: 2015-03-25
YINGSHANG TIANHAO FOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the tablets are swallowed or chewed, and the taste and flavor of the products are not good enough to arouse people's interest in taking them, especially for some people with dysphagia, such as the elderly, children, patients who have been bedridden for a long time, and other weak groups, it is unacceptable.

Method used

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  • Method for extracting multiple active nutrient contents from sea cucumber processing liquid and application of method

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Experimental program
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Effect test

Embodiment approach 1

[0035] Collect 50 kg of the working fluid from the sea and filter with a 200-mesh nylon mesh to obtain the filtrate. Add 1g of neutral protease, stir until fully dissolved, and enzymatically react at 40°C for 12h. After enzymolysis, it was incubated at 80°C for 15 minutes to inactivate the protease. The processing liquid is coarsely filtered, the pore size of the mixed cellulose coarse filter membrane is 0.45um, 50kg of distilled water is added to the processing liquid, the modified cellulose ultrafiltration membrane with a molecular cut-off of 30KD is used for ultrafiltration, and 75kg of filtrate is retained . The filtrate was added to a rotary evaporator, the temperature was set to 40°C, and the vacuum rotary evaporator was stopped when the volume reached 500 ml. The concentrated solution was subjected to a second coarse filtration through a mixed cellulose coarse filtration membrane with a pore size of 0.22um. The dextran gel G-10 column was used for desalination. The elu...

Embodiment approach 2

[0037] According to the ratio: 30 parts of the extract of Embodiment 1, 59 parts of mannitol, 10 parts of cross-linked polyvinylpyrrolidone, 1 part of peppermint flavor.

[0038] Add the materials to a rotary mixer and mix for 20 minutes, add 5% of edible ethanol, granulate by a one-step granulator, and add the granules to the tablet press to make a round tablet to obtain an oral cavity containing a variety of active nutrients Disintegrating tablets.

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Abstract

The invention relates to a method for extracting multiple active nutrient contents from sea cucumber processing liquid. The method comprises the following steps: raw material collection, primary filtration, enzymolysis, rough filtration, ultrafiltration, concentration, secondary rough filtration, desalination, fermentation, centrifugation, secondary enzymolysis, secondary centrifugation, third rough filtration, secondary ultrafiltration, secondary concentration and spray drying. The invention further relates to application of the method in orally disintegrating tablets. Compared with the prior art, the method has the advantages that a prepared sea cucumber extract contains multiple nutrient contents, and the total content of sea cucumber polypeptide, small proteins, sea cucumber mucopolysaccharide and sea cucumber glycosides reaches 80%-90%; in the whole technological process, reaction conditions are mild, no organic solvent is used, nutrient contents are hardly damaged, and molecules of the extracted sea cucumber extract are relatively small; after the sea cucumber extract is fermented by using beneficial bacteria, the nutrient contents in the sea cucumber extract are easily absorbed by human bodies, and almost no peculiar smell exists; furthermore, the technological process is very suitable for the industrial expanded production.

Description

Technical field [0001] The invention relates to a sea cucumber comprehensive utilization technology, in particular to an easily absorbed fermented sea cucumber nutrient extraction method, and an orally disintegrating tablet prepared by using it as an effective ingredient. Background technique [0002] Sea cucumbers (holothurians) belong to the class Echinodenmata (Holothunoidea). There are about 1,100 sea cucumber species in the world. China is the first country in the world to eat sea cucumbers. As early as in "The History of Foreign Objects in Sea Water" by Wei Shenying of the Three Kingdoms, there was a record of using sea cucumbers as a cooking ingredient: The abdomen, without mouth, has thirty feet like hairpins, and the larger one is more than a foot long.” The medicinal value of sea cucumbers in the Ming Dynasty was gradually discovered. The "Food Materia Medica" edited by Yao Kecheng records: "Sea cucumbers sit in the southeast sea. Like insects, black color, and many pu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P21/06C08B37/00C07J71/00A23L1/29A23L33/00
Inventor 马潘蕾郑立涌单丽辉段人钰姜颜石佳于韦
Owner YINGSHANG TIANHAO FOOD
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