Composition of composite potassium peroxymonosulfate disinfection tablet and preparation method thereof

A technology of potassium peroxymonosulfate and potassium monopersulfate, applied in the directions of disinfectants, botanical equipment and methods, chemicals for biological control, etc., can solve inconvenience in use, inaccurate measurement of powder products, and prolonged storage period and other problems, to achieve the effect of drug synergy, convenient disintegration and dissolution, and accurate dosage

Active Publication Date: 2010-09-15
镇江威特药业有限责任公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the invention is to propose a composition and preparation process of a compound potassium hydrogen persulfate disinfection tablet, to solve the problems of inaccura

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Dry the potassium monopersulfate compound salt at 40-50°C for 2 hours, pass through 30 mesh for later use; dry the adhesive at 40-80°C for 3 hours, take 60-100 mesh powder for later use; filler and lubricant , calcium oxide and peroxide were dried at 40-80°C for 3-4 hours according to the species, and passed through 30-mesh and 80-mesh sieves respectively for later use. The composition of composite potassium hydrogen persulfate disinfection tablet is as follows:

[0028] Potassium monopersulfate compound salt 10-12 (parts by weight, the same below)

[0029] Filler 55-70.0

[0030] Adhesive 15-25.0

[0031] Lubricant 8-12.0

[0032] Typically, 10.0 potassium monopersulfate compound salt, 60.0 filler, 20.0 binder, and 10.0 lubricant are weighed, mixed evenly, and pressed into tablets of required specifications with a tablet machine.

[0033] Fillers are sodium sulfate, sodium carbonate, sodium bicarbonate, trisodium bicarbonate, tetrasodium pyrophosphate, sodium tripo...

Embodiment 2

[0038] Potassium monopersulfate compound salt 20.0-30.0

[0039] Filler 30-50.0

[0040] Adhesive 1.0-10.0

[0041] Lubricant 0.01-2.0

[0042] Sodium percarbonate, calcium peroxide or sodium perborate 1-2

[0043] Fillers are sodium sulfate, sodium carbonate, sodium bicarbonate, trisodium bicarbonate, tetrasodium pyrophosphate, sodium tripolyphosphate, sodium silicate, citric, malic and tartaric acids, sodium perborate monohydrate, sodium bicarbonate , one of starch, dextrin, glucose;

[0044] The binder is one of cellulose, polyvinylpyrrolidone, and gelatin;

[0045] The lubricant is one of magnesium stearate, talcum powder, micro silica gel, sodium benzoate and polyethylene glycol;

[0046] Add calcium oxide 0.5-1; and add sodium percarbonate, calcium peroxide, calcium percarbonate or sodium perborate 1.

Embodiment 3

[0048] Potassium monopersulfate compound salt 50.0-70.0

[0049] Filler 20-40

[0050] Adhesive 1.0-10.0

[0051] Lubricant 0.01-2.0

[0052] Fillers are sodium sulfate, sodium carbonate, sodium bicarbonate, trisodium bicarbonate, tetrasodium pyrophosphate, sodium tripolyphosphate, sodium silicate, citric, malic and tartaric acids, sodium perborate monohydrate, sodium bicarbonate , one of starch, dextrin, and glucose; the binder is one of cellulose, polyvinylpyrrolidone, and gelatin;

[0053] The lubricant is one of magnesium stearate, talcum powder, micro silica gel, sodium benzoate and polyethylene glycol;

[0054] Add calcium oxide 0.5-1, add sodium percarbonate, calcium peroxide, calcium percarbonate or sodium perborate 2.

[0055] Dry the potassium monopersulfate compound salt at 40-50°C for 2 hours, pass through 30 mesh for later use; dry the adhesive at 40-80°C for 3 hours, take 60-100 mesh powder for later use; filler and lubricant , calcium oxide and peroxide wer...

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PUM

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Abstract

The invention discloses acomposite potassium peroxymonosulfate disinfection tablet which comprises 10.0-70.0 parts by weight of potassium monopersulfate, 1.0-65.0 parts by weight of fillers, 1.0-20.0 parts by weight of adhesives and 0.01-10.0 parts by weight of lubricant, wherein the fillers is formed by one or more then one of sodium sulfate, sodium chloride, potassium chloride, sodium carbonate, sodium bicarbonate, phosphate, inorganic acid, organic acid, starch, dextrin, glucose, solid emulsifier, xylitol and a metal ion complexing agent, the adhesives comprise cellulose, polyvinylpyrrolidone and gelatin; the lubricant is formed by one or more than one of magnesium stearate, talcum powder, micro-powder silica gel, sodium benzoate and polyethylene glycol; in addition, sodium percarbonate, calcium percarbonate, sodium perborate or calcium peroxide 1-2 are added. The invention is convenient to use, has the advantages of quick disintegration and dissolution, can significantly increase the effect of the disinfection tablet and can adjust pH value.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a composite potassium hydrogen persulfate disinfectant tablet. Background technique [0002] With the rapid development of today's society, the density of human living is high, and various infectious bacteria are rampant, endangering the safety of human society. Disinfection is an effective way for people to prevent various infectious bacteria. Disinfectants are widely used in the fields of sanitation and epidemic prevention, pharmaceutical and food production, livestock and poultry breeding, etc. . [0003] Potassium monopersulfate compound salt (molecular formula 2KHSO5·KHSO4·K2SO4) is composed of potassium monopersulfate, potassium hydrogensulfate and potassium sulfate. It is a white granular powder that can flow freely. It is easy to dissolve in water and decompose in water. Release oxygen and potassium sulfate without producing harmful substances. Potassium monopersulfate compound salt ha...

Claims

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Application Information

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IPC IPC(8): A01N25/34A01N59/02A01N59/00A01N59/06A01N59/14A01P1/00
Inventor 黄文江杨庆张建新戴荣贵孔令娣
Owner 镇江威特药业有限责任公司
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