The invention discloses a medicine for resisting altitude stress and production equipment, and relates to the field of medicine for resisting altitude stress. The medicine for resisting altitude stress is prepared from the following components in parts by weight: 10-20 parts of rhodiola crenulata powder, 5-10 parts of dried ginger powder, 8-10 parts of tomato powder, 5-10 parts of soybean powder, 5-10 parts of brown powdered sugar, 10-15 parts of plum powder, 2-5 parts of coenzyme Q10, 1-2 parts of selenium, 3-5 parts of a vitamin mixture and 2-4 parts of amineral matter mixture. Selenium can activate main antioxidant enzyme-glutathione anti-peroxidase in cells, soybean meal and pea meal can increase protein intake, when people enter plateau areas, protein metabolism of organisms is enhanced, sufficient high-quality protein must be eaten, and by matching with the rhodiola crenulata powder for medicine preparation, the effect of the medicine for resisting altitude stress is improved; and meanwhile, the plum powder and the brown powdered sugar are added, the sweet taste is increased through the brown powdered sugar, the sour taste is increased through the plum powder, the taste of the medicine can be adjusted, the medicine is convenient to take, and large-scale application and popularization are facilitated.