Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Evaluation method for diet protein intake of chronic kidney disease patient

A chronic kidney disease and protein technology, applied in the field of medicine, can solve problems such as poor accuracy, difficulty in taking specimens, and poor patient compliance

Active Publication Date: 2017-11-17
GUANGDONG GENERAL HOSPITAL
View PDF2 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Among them: GU(mg / min)=Curea(ml / min)(BUN(mg / ml),Curea(ml / min)=[Uurea(mg / ml) / BUN(mg / ml)]×[urine output( ml) / time (min)] (Note: GU is urea generation rate; Curea is urea clearance rate; Uurea is urine urea nitrogen concentration; BUN is blood urea nitrogen); this formula calculates the relevant biochemical indicators that need to be detected simultaneously in blood and urine , because of too cumbersome clinical application is not common
[0011] In summary, the above-mentioned methods have shortcomings such as tediousness, long detection time, poor accuracy, difficulty in specimen collection, or poor patient compliance. At present, there is an urgent need for a method that can be used for outpatient follow-up, simple blood draw or single urination to estimate DPI. Methods

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Evaluation method for diet protein intake of chronic kidney disease patient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0027] The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0028] Implementation object and time: recruit patients with chronic kidney disease stage 3 (CKD3) in stable condition, and plan to enroll 108 cases. Each patient was followed up for 7 days and is expected to be completed within 1 year.

[0029] Diet plan: In a low-protein diet, the daily dietary protein intake is about 0.7 grams / kg body weight, the daily dietary calorie intake is about 30 kcal / kg body weight, the daily salt intake is less than 6 grams, and the daily phosphorus intake is 0.8- 1.0 grams, the total daily calcium intake is less than 1500 mg (including meals and drugs).

[0030] Main indicators: blood urea nitrogen (BUN) and creatinine (sCr), serum albumin, transferrin, prealbumin, C-reactive protein, morning random urine urea nitrogen (UUN) and creatinine (Cr), urine albumin / creatinine Ratio (ACR), urine protein / creatin...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an evaluation method for diet protein intake (DPI) of a chronic kidney disease (CKD) patient. Through research of relationships between a fasting serum blood urea nitrogen / creatinine ratio (BUN / Cr) and a single-time urine urea nitrogen / creatinine ratio (UUN / Cr) of a CKD third-phase patient with a stable illness state, and the diet protein intake (DPI), a DPI simple calculation formula based on the fasting serum BUN / Cr and / or random urine UUN / Cr is established. According to the final calculation formula, it is expected that a traditional method for evaluating the DPI through subsistence of the urine within 24 hours can be replaced by a biochemical detection result of a single-time blood or urine in clinical follow-up. Defects such as complexity, long detection time, poor accuracy, difficult sample subsistence or low patient compliance in the traditional method are overcome. Clinically, the method can be used for clinical follow-up, simple blood drawing or single-time urination, thereby evaluating the DPI. The method can be used for managing the diet protein intake of the CKD patient well, fast and conveniently.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an evaluation method for dietary protein intake of patients with chronic kidney disease. Background technique [0002] The currently commonly used methods for evaluating dietary protein intake (DPI) mainly include dietary survey, 24-hour urine measurement of urea nitrogen, urea nitrogen expression rate, protein equivalent, and protein decomposition rate. Among them, 1) dietary survey: dietary survey as An important tool in nutrition research, most patients review their 24-hour diet or record their own diet for 3 to 7 days, and use the conversion of common food nutrients to calculate protein intake; this method requires experienced physicians or nutritionists. Time-consuming, highly subjective, and prone to errors. Some studies believe that this method tends to overestimate the patient’s real protein intake. Therefore, it is difficult for doctors to complete dietary s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G06F19/00G01N31/00G01N33/50G01N33/68
CPCG01N31/002G01N33/50G01N33/6893G01N2800/34
Inventor 王文健汪延辉谢剑腾文枫王端李真李盛李静黄建中付蕾李锐钊叶智明章斌刘双信梁馨苓
Owner GUANGDONG GENERAL HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products