32 results about "Leg ulcer" patented technology

The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more pieces of collagen biofabric for the treatment of a leg ulcer.

Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and the water has a redox potential of >950 mV. Medicaments based on the super-oxidized water may be in liquid or gel form. The super-oxidized water is able to control the microbial population within the wound and at the same time permit cell proliferation.

The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more pieces of collagen biofabric for the treatment of a leg ulcer.

A knitted therapeutic compression and cushion sock and a method for making such a sock include a terry-knit cushioning layer in selected bottom portions of the sock, allowing for greater ventilation and cooling in the top portion. The sock includes graduated zones of compressive pressures. Gradual changes in compressive pressures from one zone of compressive pressure to another can be provided by compression flaring, or changing the feed rate of elasticized yarn during knitting at or near the interface of two zones having different compressive pressures. Such a sock is useful for padding and compressing foot and leg areas to both prevent and treat vascular and skin conditions such as foot and leg ulcers.

An ulcer, lymphoedema and DVT treatment device (10) comprises a drive unit (12) adapted to deliver mechanical vibrations at its surface in three orthogonal directions at a frequency in each orthogonal direction of between 15 and 75 Hz and with an amplitude in each orthogonal direction of between 0.1 and 0.5 mm. A pad (110) is connected to the drive unit, and a strap (46) enables the pad to be pressed against the limb of the animal or human. The motor drives an eccentrically mounted weight (22) to provide oscillations of the casing in a radial plane. The device is employed to treat a patient suffering from leg ulcers, lymphoedema and DVT by applying three-dimensional vibrations. A cover (150) is provided to protect the pad (110) from contamination.

There is disclosed a method for treating dermatologic diseases caused by microbial overgrowth or inflammation, such as psoriasis, fungal infections, eczema, dandruff, acne, genital herpes lesions, and leg ulcers. There is further disclosed an antiviral lubricating composition that is effective in preventing the transmission of the HIV virus and other sexually transmitted diseases. There is also disclosed systemic and anti-inflammatory compositions and formulations and a method for reducing tissue inflammation in tissues such as the bowel, muscle, bone, tendon and joints (e.g., arthritis).

In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and / or ichthammol and in the presence or absence of antimicrobial agent (inorganic and / or organic). An optional outer layer comprises a short / long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

A novel polypeptide, and an antibacterial agent, antifungal agent and / or antiseptic containing as an effective ingredient the polypeptide are disclosed. The polypeptide of this invention has an amino acid sequence shown in SEQ ID NOs:1 to 12 and 13 to 31. This antibacterial agent, antifungal agent and / or antiseptic is useful for the prevention, amelioration or treatment of diseases such as burn, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliterans, cellulitis, acute lymphangitis, lymphadenitis, erysipelas, skin abscess, necrotizing subcutaneous infection, staphylococcal scalded skin syndrome (SSSS), folliculitis, facial furuncle, suppurative hidradenitis, carbuncle, infectious paronychia, erythrasma and severe infection (sepsis).

The invention discloses a drug for mainly treating leg ulcer. The drug is characterized by being made from the following parts of raw materials by weight: 25-35 parts of yellow lead, 17-23 parts of dragon blood, 13-17 parts of camphor, 17-23 parts of calamine, 13-17 parts of dried alum, 13-17 parts of calcined gypsum, 13-17 parts of ginseng, 13-17 parts of astragalus root, 13-17 parts of Chinese goldthread, 13-17 parts of Chinese teasel root, 13-17 parts of dahurian angelica root, 13-17 parts of manyleaf paris rhizome, 13-17 parts of honeysuckle, 13-17 parts of anomalous wormwood, 13-17 parts of panicled swallowwort root, 17-23 parts of pearl, 17-23 parts of poppy shell, 17-23 parts of pseudo-ginseng, 17-23 parts of cnidium fruit, 17-23 parts of climbing groundsel, 17-23 parts of Chinese lobelia, 17-23 parts of borneol, 17-23 parts of natural indigo and 17-23 parts of leaf of Chinese ilex. The drug has the beneficial effects of good curative effect, convenient use, and simple preparation, and can activate blood circulation to dissipate blood stasis, eliminate necrotic tissues and promote granulation, improve the blood supply of wound surface, cause the granulation to regenerate tissue while expelling rotten materials, and can improve conditions for accelerated wound healing, and has instant effect.

In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and / or ichthammol and in the presence or absence of antimicrobial agent (inorganic and / or organic). An optional outer layer comprises a short / long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

A device which comprises an enclosure of a plastics material, having an opening at an end thereof with fastening means to enable the opening to be closed around a limb or stump with an affected part contained within the enclosure, and including a fluid-absorbent material within the enclosure. The device is particularly suitable for use in the treatment of leg ulcers.

The present invention relates to the use of a composition comprising pentane-1, 5-diol to reduce and / or eliminate odour from a mammal, such as odour from such as urine, faeces, liquids from leg ulcers, decubital ulcers, blood and perspiration. The invention also relates to absorbent and / or sanitary products comprising pentane-1, 5- diol.

A method for preventing and / or treating a disease associated with increased interleukin-1β and / or interleukin-6 and / or interleukin-8 activity and / or disease, in which a reduction in the activity of interleukin-1β and / or interleukin-6 and / or interleukin-8 is beneficial for healing includes utilizing a silicon-containing, biodegradable material containing a polyhydroxysilicic acid ethyl ester compound, with the proviso that wound defects including chronic diabetic-neuropathic ulcer, chronic leg ulcer, bedsores, secondary-healing infected wounds, non-irritating, primary-healing wounds, ablative lacerations and / or abrasions, are excluded from said disease that is prevented and / or treated with the silicon-containing, biodegradable material.

A deproteinized calf blood capsule for treating the nerve function deficiency, artery vessel diseases, leg ulcer, burn, scald, erosion, wound, etc is composed of an enteric shell and a medicine prepared from the extract of deproteinized calf blood, starch and bacterial depressant. Its preparing process is also disclosed.

The present application discloses angiogenic peptides that cause intracellular calcium release in target cells and thereby induce proliferation, migration, and capillary-like tube formation in primary cultured endothelial cells. The angiogenic peptides can be used for preventing and / or treating angiognesis-related conditions, especially wound healing, treating foot and leg ulcers in a subject, etc. In addition, the angiogenic peptides can be used for cosmetics a constituent of cosmetics for aged skin, for examples, anti-wrinkle and skin whitening.

The invention relates to a silica gel application and a using method and application thereof, belongs to the field of medical applications, and particularly relates to a silica gel application and a using method and application thereof. The silica gel application comprises release paper; a wound contact layer, a flow guide layer, a middle water absorption layer and a waterproof protection layer, wherein the wound contact layer is made of silica gel material; the flow guide layer is made of SS non-woven fabrics; the middle water absorption layer is made of a PAS water absorption material; the waterproof layer is made of SMS; and silica gel and the flow guide layer as well as the periphery of the flow guide layer and the periphery of the waterproof layer are bonded together in an ultrasonicheat sealing mode. The silica gel application can be specially used for nursing acute and chronic wounds with moderate to severe exudation. Besides, the silica gel application can be used together with alginate for a cavity hole type wound in the using process, and can be combined with a pressure bandage for pressure therapy for leg ulcer. The silica gel application is rapid in seepage conduction,high in liquid absorption rate, capable of being repeatedly pasted, free of deformation, displacement and falling, transparent, easy to fix and beneficial to wound healing.

The present invention relates to a composition and a method for treatment of injury caused or complicated by infections such as pneumonia, injuries in the respiratory organs caused by burns and / or infections and infected chronic leg ulcers in the patients suffering from diabetes, venous or combined venous / arterial insufficiency, wherein a therapeutically active amount of HGF (hepatocyte growth factor) and at least antibiotic agent, to which the infection in question respond, are administered to a mammal suffering from such injury. The present invention also relates to analysis of excrement with regard to HGF, as well as a kit for carrying out the analysis for the diagnosis of certain illness conditions where HGF has turned out to be an important factor.

A novel polypeptide, and an antibacterial agent, antifungal agent and / or antiseptic containing as an effective ingredient the polypeptide are disclosed. The polypeptide of this invention has an amino acid sequence shown in SEQ ID NOs:1 to 12 and 13 to 31. This antibacterial agent, antifungal agent and / or antiseptic is useful for the prevention, amelioration or treatment of diseases such as burn, decubitus, wound, skin ulcer, leg ulcer, diabetic ulcer, occlusive arterial disease and arteriosclerosis obliterans, cellulitis, acute lymphangitis, lymphadenitis, erysipelas, skin abscess, necrotizing subcutaneous infection, staphylococcal scalded skin syndrome (SSSS), folliculitis, facial furuncle, suppurative hidradenitis, carbuncle, infectious paronychia, erythrasma and severe infection (sepsis).

A device which comprises an enclosure of a plastics material, having an opening at an end thereof with fastening means to enable the opening to be closed around a limb or stump with an affected part contained within the enclosure, and including a fluid-absorbent material within the enclosure. The device is particularly suitable for use in the treatment of leg ulcers.

An ulcer, lymphoedema and DVT treatment device (10) comprises a drive unit (12) adapted to deliver mechanical vibrations at its surface in three orthogonal directions at a frequency in each orthogonal direction of between 15 and 75 Hz and with an amplitude in each orthogonal direction of between 0.1 and 0.5 mm. A pad (110) is connected to the drive unit, and a strap (46) enables the pad to be pressed against the limb of the animal or human. The motor drives an eccentrically mounted weight (22) to provide oscillations of the casing in a radial plane. The device is employed to treat a patient suffering from leg ulcers, lymphoedema and DVT by applying three-dimensional vibrations. A cover (150) is provided to protect the pad (110) from contamination.

The invention discloses new purpose of a human Keratiocyte growth factor 1 applied to treatment of foot ulcers and leg ulcers of diabetes. In the invention, the biological activity of proliferation of epithelial cells is promoted by using the specificity of the human Keratiocyte growth factor 1 to repair the damage of the epithelial, and the structural restoration of the foot ulcers and leg ulcers of diabetes promoted to achieve the treatment of the foot ulcers and leg ulcers of diabetes.

The invention relates to a pharmaceutical composition comprising 2,5-dihydroxybenzenesulfonic acid or a pharmaceutically acceptable salt thereof in the form of personalised supply units and a corresponding manufacturing method. The pharmaceutical composition comprising 2,5-dihydroxybenzenesulfonic acid or a pharmaceutically acceptable salt thereof in the form of personalised supply units, in which part of the 2,5-dihydroxybenzenesulfonic acid is in the form of an immediate-release composition additionally comprising between 8% and 28% microcrystalline cellulose, and the other part of which is in the form of a prolonged-release composition additionally comprising between 10% and 45% hydroxypropylmethylcellulose and between 6.1% and 20% hydroxypropylcellulose. The proportion between the two parts is between 24:76 and 40:60. This allows administration of the composition to the patient once every 24 hours. The composition can be used to treat primary varicose states, chronic venous insufficiency, phlebitis, thrombophlebitis, post-thrombotic syndrome, leg ulcers, pregnancy-related varicose veins. as a coadjuvant for varicectomy, sclerotherapy or as a coadjuvant in the treatment of diabetic retinopathy.

The present disclosure is related to a method of managing diabetic foot ulcers (DFUs), pressure ulcers, venous leg ulcers and associated complications such as bacterial infection, gangrene, tissue necrosis, amputation, proximal limb loss and septicaemia. This method of managing is by administration of pharmaceutical composition comprising pentameric type A procyanidin, trimeric procyanidin and tetrameric procyanidin, optionally along with pharmaceutically acceptable excipient.

The invention discloses a traditional Chinese medicine multi-component liquid wound healing dressing and a preparation method thereof. The traditional Chinese medicine multi-component liquid wound healing dressing is prepared from extracts of traditional Chinese medicine compositions of bletilla striata, pseudo-ginseng, callicarpa bodinieri, pollen typhae, ligusticum wallichii, armadillidiam vulgare and coptis chinensis by taking bletilla striata gum as a film-forming agent. The traditional Chinese medicine multi-component liquid wound healing dressing can be used for all kinds of mechanical skin injuries, chronic infected wounds, leg ulcers, diabetic foot ulcers and other trauma. According to the traditional Chinese medicine multi-component liquid wound healing dressing, the bletilla striata gum is used as a novel film-forming material to replace an existing chemical film-forming agent, is non-toxic and non-irritant, and has the advantages of being degradable, capable of diminishing inflammation and stopping bleeding, rapid in film forming and capable of protecting the wounds and the like; the traditional Chinese medicine composition is combined according to the principle of 'monarch, minister, assistant and guide', all the medicines have a synergistic effect, the effects of sterilizing, relieving pain, diminishing swelling and promoting tissue regeneration are enhanced, and meanwhile, the process route has reasonability, scientificity and reliability.

The invention discloses a traditional Chinese medicine capsule for treating leg ulcer. The traditional Chinese medicine capsule is prepared from the following traditional Chinese medicinal materials in parts by weight: 15 parts of angelica, 15 parts of ligusticum wallichii, 15 parts of peach kernel, 9 parts of herba centellae, 15 parts of morinda angustifolia, 30 parts of raw radix astragalis, 15 parts of eel blood, 9 parts of leaves of purpleflower holly, 5 parts of sapium baccatum, 5 parts of incarvillea younghustandii sprague, 12 parts of aizoon stonecrop herb, 6 parts of mutton tallow, 15 parts of tobaccos, 6 parts of raw liquorice, 6 parts of broken pine pollen and 6 parts of wild sword beans. Clinical experiments prove that the traditional Chinese medicine capsule, by selecting proper medicinal materials and proportions thereof, can achieve a significant effect of treating leg ulcer, and the traditional Chinese medicine capsule is safe and free from toxic or side effect.

The invention relates to a plaster for treating scabies, legs and skin ulcers, which is characterized in that 20 flavors of traditional Chinese medicines such as whole worms and earth elements that have been dried for use are put into sesame oil for heating according to the weight components, and the sesame oil is boiled with a low fire Remove from the heat and let it stand for 3 to 5 days. Boil the medicinal oil on low heat. When the medicinals are all floating on the oil surface, remove from the heat when the medicinals turn yellow. After cooling, filter out the medicinal oil for later use. Then put the spare medicinal oil into the iron pot Boil until water drips into beads, then quickly put Hongshengdan into the medicinal oil according to the weight component, and stir while lowering, when the oil and Dan boil, there will be thick black smoke, until it starts to emit blue-gray smoke, remove from the fire , that is to make a plaster, then pour the crushed and bottled frankincense, myrrh, and musk into the plaster, then add gallnut powder, stir well, and when the temperature of the plaster drops to 35-45°C, pour the plaster slowly Remove the fire and poison in cold water to make this plaster. The invention can not only treat ecthyma, leg ulcers and skin ulcers, but also has small scars after healing, is not easy to relapse, has remarkable curative effect and wide source of medicine, and is not easy to relapse after curing.

A medicine for treating skin diseases or lower extremity ulcers in patients with diabetes. ~50 grams, 1~5 grams of Naoyanghua, 10~100 grams of Smilax smilax, add water to adjust to 1000 ml. When preparing the medicine for the treatment of skin diseases, put Angelica dahurica, Artemisia argyi, Eucalyptus eucalyptus, Flos argyi, and Smilax tuckahoe into a steamer according to the formula, add 1000 ml of water and decoct for 1 to 4 hours, then add alum, and continue steaming. After boiling for a certain period of time, filter the medicinal soup and add water to adjust to 1000 ml. The medicine for treating skin diseases of the present invention has better treatment effect, short cycle, no need to take medicine, injection or operation, and low cost, and is particularly effective for treating diabetic patients with lower extremity ulcers, thereby avoiding the unfortunate amputation of diabetic patients, and preparing the medicine The method is simple.

The invention relates to the technical field of external Chinese patent medicines and especially relates to detoxifying granulation-promoting powder and a preparation method thereof. The detoxifying granulation-promoting powder comprises the following dry Chinese herbal medicine materials in parts by weight: 10-20 parts of herba hyperici japonica, 12-25 parts of bear bile, 10-22 parts of melothria heterophylla, 5-20 parts of dandelion, 11-19 parts of scabrous elephantfoot herb and 5-25 parts of eclipta. The detoxifying granulation-promoting powder prepared from various medicines can effectively neutralize the acidity of wound, can solve various problems caused by acidity, has the effects of comprehensively activating blood, promoting qi circulation, dispersing blood stasis, relieving toxicity, activating channels and collaterals, diminishing inflammation, removing stasis, stopping bleeding and pain, detoxifying, expelling pus, sterilizing, preventing infection and activating surrounding necrotic core nerves, has excellent therapeutic effects for various difficult healed wounds, such as rotten wounds, bedsores, rotten ulcers, leg ulcers, diabetic wound and traumatic wound, is wide in therapeutic range, is short in medication time, can quickly become effective, has a special effect for difficult miscellaneous wound diseases and is free from side effect.

The invention discloses a drug for mainly treating leg ulcer. The drug is characterized by being made from the following parts of raw materials by weight: 25-35 parts of yellow lead, 17-23 parts of dragon blood, 13-17 parts of camphor, 17-23 parts of calamine, 13-17 parts of dried alum, 13-17 parts of calcined gypsum, 13-17 parts of ginseng, 13-17 parts of astragalus root, 13-17 parts of Chinese goldthread, 13-17 parts of Chinese teasel root, 13-17 parts of dahurian angelica root, 13-17 parts of manyleaf paris rhizome, 13-17 parts of honeysuckle, 13-17 parts of anomalous wormwood, 13-17 partsof panicled swallowwort root, 17-23 parts of pearl, 17-23 parts of poppy shell, 17-23 parts of pseudo-ginseng, 17-23 parts of cnidium fruit, 17-23 parts of climbing groundsel, 17-23 parts of Chinese lobelia, 17-23 parts of borneol, 17-23 parts of natural indigo and 17-23 parts of leaf of Chinese ilex. The drug has the beneficial effects of good curative effect, convenient use, and simple preparation, and can activate blood circulation to dissipate blood stasis, eliminate necrotic tissues and promote granulation, improve the blood supply of wound surface, cause the granulation to regenerate tissue while expelling rotten materials, and can improve conditions for accelerated wound healing, and has instant effect.

A deproteinized calf blood capsule for treating the nerve function deficiency, artery vessel diseases, leg ulcer, burn, scald, erosion, wound, etc is composed of an enteric shell and a medicine prepared from the extract of deproteinized calf blood, starch and bacterial depressant. Its preparing process is also disclosed.