10 results about "Methylcyclopentadiene" patented technology

The application discloses a high-activity 8-hydroxyquinoline rhodium complex in vivo and in vitro and a synthesis method and application thereof. The 5,7-dichloro-8-hydroxy-2-methylquinoline, dichloro (pentamethylcyclopentadienyl) rhodium (III) dimer, methanol, dimethyl sulfoxide and triethylamine are taken, and under a closed condition, the reaction is carried out at 80 DEG C for 3 days; after being cooled to 37 DEG C, filtration and drying are carried out, and the 5-chloro-8-hydroxyquinoline rhodium complex is obtained. The 5-chloro-8-hydroxyquinoline rhodium complex has obvious inhibiting effect on SK-OV-3 and SK-OV-3 / DDP cancer cells, shows superior antitumor activity, and has small toxicity to normal HL-7702 cells; the 5-chloro-8-hydroxyquinoline rhodium complex has potential medicinal value and is expected to be used for preparation of various antitumor drugs.

This invention discloses a synthesis process for methylnadic anhydride, comprising the following steps: maleic anhydride is dissolved in a solvent, and methylcyclopentadiene or a starting material containing 60-98 wt% methylcyclopentadiene is added dropwise at a uniform rate at 10-60°C to carry out a synthesis reaction, wherein the mass ratio of methylcyclopentadiene to maleic anhydride is (0.5-1.2):1; after the reaction is completed, light components are removed under reduced pressure, the light components including the solvent, unreacted methylcyclopentadiene and its dimer, and then isomerization is carried out at 140-200°C to obtain methylnadic anhydride.

This invention discloses an anti-drug-resistant lung cancer compound, its preparation method, and its applications. The invention involves reacting 5-chloro-8-hydroxyquinoline, dichloro(pentamethylcyclopentadienyl)rhodium(III) dimer, methanol, dimethyl sulfoxide, and triethylamine under sealed conditions at 80 °C for 3 days. After cooling to 37 °C, the mixture is filtered and dried to obtain the final product. The 5-chloro-8-hydroxyquinoline rhodium complex exhibits superior antitumor activity by targeting and inhibiting the growth of lung cancer cells A549 and cisplatin-resistant lung cancer cells A549 / DDP, while showing low toxicity to normal HL-7702 cells. It possesses potential pharmaceutical value and is expected to be used in the preparation of various antitumor drugs.

This invention provides a method for preparing tris(methylcyclopentadienyl)yttrium. This method can efficiently remove key impurities, simplifying the process while effectively improving the purity and yield of tris(methylcyclopentadienyl)yttrium. The preparation method includes the following steps: S1, under an inert atmosphere, methylcyclopentadiene and a bis(trimethylsilyl)amino potassium salt solution are mixed at a temperature ≤30°C, and then the temperature is raised to 75-85°C for reaction; after the reaction, the mixture is filtered under reduced pressure to obtain a cyclopentadienyl potassium salt intermediate; S2, under an inert atmosphere, yttrium trichloride and the cyclopentadienyl potassium salt intermediate are mixed in the presence of a solvent, and then the temperature is raised for reaction; after the reaction, the mixture is filtered, the filtrate is collected, and the filtrate is concentrated under reduced pressure to obtain a crude product; S3, the crude product is pretreated by reduced pressure distillation to obtain a pretreated product; then, it is sublimated under vacuum to obtain the tris(methylcyclopentadienyl)yttrium.

This invention discloses a method for manufacturing a Y₂O₃ thin film, a method for forming a protective coating material for semiconductor manufacturing components, and a semiconductor manufacturing component. The objective of this invention is to provide a method for manufacturing a Y₂O₃ thin film that exhibits resistance to high-density fluorocarbon-based plasma. To achieve this objective, this invention uses bis(methylcyclopentadienyl)(N'-isopropyl-N-n-propylacetamidinate)yttrium (Y(MeCp)₂(iPr-nPrAMD)) as a precursor to manufacture an ALD-Y₂O₃ thin film.

This invention belongs to the field of chemical production technology, specifically disclosing a purification method for trimethoxy(pentamethylcyclopentadienyl)titanium, comprising the following steps: vacuum distillation of crude trimethoxy(pentamethylcyclopentadienyl)titanium raw material to obtain a crude distillate; adding 5-20 parts by mass of a modifier to 100 parts by mass of the crude distillate, wherein the modifier is at least one selected from triethylene glycol dibutyl ether, tetraethylene glycol dibutyl ether, n-heptadecane, n-octadecane, and mineral oil, and then distilling to obtain the product. This invention achieves large-scale purification of Star-Ti, achieving a distillation yield of over 75%, with a maximum of over 95%, and obtaining a high-purity product with an organic purity of over 99.5%, solving the problems of difficult large-scale purification, difficulty in purity improvement, and low recovery rate of Star-Ti in existing technologies.

The application discloses a method for synthesizing a nickel-modified platinum-based nitrogen-doped graphdiyne catalyst based on an atomic layer deposition technology and application thereof, and the method comprises the following steps: vacuum ball milling and calcining and purifying hexabromobenzene and calcium carbide to obtain a graphdiyne carrier; mixing and calcining the carrier and melamine to realize nitrogen doping of the carrier; using atomic layer deposition technology to load platinum nanoparticles on the nitrogen-doped graphdiyne by taking trimethylcyclopentadienyl platinum (MeCpPtMe3) as a platinum source; and using atomic layer deposition technology to deposit an ultrathin nickel layer on the surface of the platinum nanoparticles by taking nickelocene (NiCp2) as a nickel source to obtain the catalyst. The method utilizes the atomic-level surface regulation characteristics of the atomic layer deposition technology, and realizes effective optimization of the electronic structure of the surface of the platinum nanoparticles by accurately controlling the deposition cycle number of nickel. The nickel-modified platinum-based nitrogen-doped graphdiyne catalyst prepared by the method exhibits excellent electrocatalytic activity and kinetic performance, and provides a high-efficiency low-platinum catalyst solution for a zinc-air battery.

A method for manufacturing a Y2O3 thin film capable of exhibiting resistance to fluorocarbon-based high-density plasma is described. An ALD-Y2O3 thin film is manufactured using bis(methylcyclopentadienyl)(N′-isopropyl-N-n-propylacetamidinate) yttrium (Y(MeCp)2(iPr-nPrAMD)) as a precursor.

The application discloses a method for preparing methyl nadic anhydride by using carbon nine and carbon ten fraction, high-purity methyl cyclopentadiene obtained by cracking and separation of the carbon nine and carbon ten fraction; the methyl cyclopentadiene is used as raw material and is added dropwise into a synthesis reactor, and is subjected to a synthesis reaction with maleic anhydride dissolved and dispersed in a solvent in the synthesis reactor under nitrogen protection and stirring at 10-60 DEG C; the reaction product enters a light component recovery tower, unreacted methyl cyclopentadiene, solvent and methyl cyclopentadiene dimer are removed from the top of the tower, crude methyl nadic anhydride is collected from a side line and enters an isomerization reactor for isomerization reaction; the isomerization reaction product enters an MNA post-treatment device, and is subjected to vacuum distillation / rectification to obtain a methyl nadic anhydride product.

This application relates to a method for preparing carbamate compounds from dioxazolone derivatives, comprising the following steps: reacting a dioxazolone derivative with a hydroxyl-containing compound in the presence of a catalyst to prepare the carbamate compound. The catalyst includes one or more of dichlorobis(4-methylisopropylphenyl)ruthenium(II), tri(acetylacetonate)ruthenium(III), cyclooctadiene ruthenium(II) chloride, and dichloro(pentamethylcyclopentadienyl)iridium(III) dimers. This synthetic method is universally applicable to the synthesis of carbamate compounds with different group types (such as alkyl, aryl, heteroaryl, etc.), and exhibits high yields and mild reaction conditions.