Areca catechu seed flavoured products

Abstract

To provide Areca catechu seed flavored products containing arecoline salts.SOLUTION: Arecoline salt is obtained by neutralizing arecoline with a compounding acid. The compounding acid is at least one of formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, and the like. A product is an aerosol, chewing gum, or filter capsule.SELECTED DRAWING: None

Description

[Technical field]

[0001] [CROSS REFERENCE TO RELATED APPLICATIONS] This application claims priority to Chinese Patent Application No. 202010587899.7, entitled "Betel Nut Flavored Product", filed with the China Patent Office on June 24, 2020, and Chinese Patent Application No. 202010227895.8, entitled "Aerosol-Forming Substrate", filed with the China Patent Office on March 27, 2020, the entire contents of which are incorporated herein by reference.

[0002] The present application is in the technical field of chemical synthesis and relates to areca nut flavored products. [Background technology]

[0003] Arecoline, whose chemical name is 1,2,5,6-tetrahydro-1-methyl-3-methylpicolinate, is an oily liquid with cholinergic properties. Arecoline is a valuable compound, and its preparation method and applications have always been of interest.

[0004] However, the properties of arecoline are unstable, and there are currently no products on the market, so it is not possible to confirm the conversion rate of arecoline, nor is it possible to confirm whether chewing betel nut can achieve a similar effect, and the application of arecoline salts in products has not yet been found. Summary of the Invention

[0005] The present application provides a betel nut flavored product, said product comprising arecoline salt.

[0006] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a compounding acid.

[0007] In some embodiments, the compounding acid of the arecoline salt is At least one of formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0008] In some embodiments, the molar ratio of the arecholine to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0009] In some embodiments, the product is an aerosol-forming substrate for generating an aerosol for inhalation by atomization.

[0010] In some examples, based on the total mass of the aerosol-forming substrate, the mass percentage of the arecholine salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, still more preferably 2% - 10%, still more preferably 2% - 5%, still more preferably 2% - 4%, and more preferably 3% - 4%.

[0011] In some examples, the arecholine salt is arecholine hydrobromide and / or arecholine benzoate.

[0012] In some embodiments, the method for preparing the arecoline salt includes using ethyl acetate as an extractant to extract arecoline from areca nut, adjusting the pH value of the extract to 7.5-8.5, taking the ethyl acetate layer, and further adding hydrobromic acid or benzoic acid to generate arecoline salt crystals, and recrystallizing the arecoline salt crystals to obtain arecoline hydrobromide or arecoline benzoate.

[0013] In some embodiments, the aerosol-forming substrate further comprises a solvent and a fragrance.

[0014] In some embodiments, the solvent is Contains at least one of the following ingredients: propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, palm oil, peanut oil, corn oil, and salad oil.

[0015] In some embodiments, the solvent comprises glycerin, and the mass percentage of glycerin in the aerosol-forming substrate is between 0 and 90%.

[0016] In some embodiments, the solvent comprises propanediol, and the mass percentage of propanediol in the aerosol-forming substrate is between 9% and 99.8%.

[0017] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0018] In some embodiments, the aerosol-forming substrate is in a liquid phase and is used to generate an aerosol by atomization using any one of a heated atomizer, an ultrasonic atomizer, an air compression atomizer, or a pressure spray device.

[0019] In some embodiments, the aerosol-generating substrate is in a solid phase and is configured to generate an aerosol for inhalation when heated below its ignition point.

[0020] In some embodiments, the article is a filter capsule for use in an aerosol-generating article.

[0021] In some embodiments, the product is a chewing gum.

[0022] In some embodiments, the product is a beverage.

[0023] In this application, when using arecoline salt in a product, the user can inhale arecoline when smoking and produce an effect similar to chewing betel nuts, with less irritation.

Embodiments for Carrying out the Invention

[0024] In combination with the following examples, this application will be further described.

[0025] Embodiment 1 Embodiment 1 of this application provides the use of arecoline salt in the preparation of an aerosol-forming substrate.

[0026] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with an acid for formulation. In some embodiments, the acid for formulation of the arecoline salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0027] In some embodiments, the molar ratio of the arecoline to the acid for formulation is n, where the range of the value of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0028] In some embodiments, when the aerosol-forming substrate is prepared, the mass percentage of the arecoline salt relative to the total mass of the aerosol-forming substrate is 0.2% to 15%, preferably 1% to 15%, more preferably 2% to 15%, more preferably 2% to 10%, more preferably 2% to 5%, and even more preferably 2% to 4%.

[0029] In some embodiments, substances that are added to the arecoline salt when preparing the aerosol-forming substrate include a solvent.

[0030] In some embodiments, the solvent is The additive is selected from at least one of 1,2-propanediol, 1,3-propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0031] In some embodiments, the solvent includes glycerin, and the mass percentage of the glycerin is 0 to 90%.

[0032] In some embodiments, the solvent comprises propanediol, and the mass percentage of the propanediol is between 9% and 99.8%.

[0033] In some embodiments, the object to which the arecoline salt is added further comprises a fragrance.

[0034] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0035] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0036] In some embodiments, the substance to which the arecoline salt is added does not include nicotine and / or a nicotine salt.

[0037] EMBODIMENT 2 Embodiment 2 of the present application provides an aerosol-forming substrate, the aerosol-forming substrate comprising: Arecoline salt, A solvent; and an optional fragrance.

[0038] Preferably, the mass percentage of the arecoline salt relative to the total mass of the aerosol-forming substrate is 0.2% to 15%, preferably 1% to 15%, more preferably 2% to 15%, even more preferably 2% to 12%, even more preferably 2% to 10%, even more preferably 2% to 8%, even more preferably 2% to 5%, even more preferably 2% to 4%, even more preferably 2% to 3%, and more preferably 3% to 4%.

[0039] Preferably, the compounding acid of the arecoline salt is At least one of the following acids may be included: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, and histidine.

[0040] Preferably, the arecoline salt is arecoline hydrobromide and / or arecoline benzoate.

[0041] Preferably, the arecoline salt is obtained by neutralizing arecoline extracted from areca nut with the compounding acid.

[0042] Preferably, the arecoline salt is arecoline hydrobromide or arecoline benzoate, and the preparation method involves using ethyl acetate as an extractant to extract arecoline from areca nut, adjusting the pH value of the extract to 7.5-8.5, taking the ethyl acetate layer, and further adding hydrobromic acid or benzoic acid to generate arecoline salt crystals, and recrystallizing the arecoline salt crystals to obtain arecoline hydrobromide or arecoline benzoate.

[0043] Preferably, the solvent is Contains at least one of the following ingredients: propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, palm oil, peanut oil, corn oil, and salad oil.

[0044] Preferably, the solvent contains glycerin, and the mass percentage of glycerin contained in the aerosol-forming substrate is 0 to 90%, preferably 0% to 80%, more preferably 0% to 70%, even more preferably 0% to 60%, even more preferably 10% to 60%, even more preferably 20% to 60%, even more preferably 30% to 60%, even more preferably 40% to 60%, and more preferably 50% to 60%.

[0045] Preferably, the solvent contains propanediol, and the mass percentage of propanediol contained in the aerosol-forming substrate is 9% to 99.8%, preferably 9% to 90%, more preferably 9% to 80%, even more preferably 9% to 70%, even more preferably 9% to 60%, even more preferably 9% to 50%, even more preferably 20% to 50%, even more preferably 30% to 50%, and more preferably 35% to 45%.

[0046] Preferably, the aerosol-forming substrate comprises a fragrance, the fragrance comprising: cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0047] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0048] Test Method: As the arecoline salt, arecoline hydrobromide is selected. As the solvent, a mixture of glycerin and propanediol in a mass ratio of 1:1 is selected.

[0049] A smoker was used according to international standards, and the aerosol atomized from the aerosol-forming substrate was collected by a Cambridge filter and tested, confirming that the mass of arecoline hydrobromide in the aerosol was m1. The mass of arecoline hydrobromide remaining in the aerosol-forming substrate was then confirmed to be m2, and the mass of total arecoline hydrobromide in the aerosol-forming substrate was confirmed to be m0, and the conversion rate k=m1 / (m0-m2) was calculated.

[0050] Here, the relevant international standards are: You may refer to CORESTARE COMMENDED METHODS NO. 81, Afhor standardization XPD90-300-3, International Standard ISO20768:2018 and PDCEN / TR17236:2018.

[0051] The parameters for vaping an e-cigarette are: JPEG2025004112000001.jpg98170

[0052] Puff Experience Test: After the aerosol-forming substrate is atomized, the puff experience of the aerosol-forming substrate can be evaluated from two aspects: the satisfaction after the smoker inhales the arecoline salt, and the discomfort after the smoker inhales the arecoline salt excessively. By combining the puff evaluations of several people and the two aspects of experience, various aerosol-forming substrates are scored with 0-5 points to obtain an embodiment with a better puff experience.

[0053] Test results: JPEG2025004112000002.jpg117170

[0054] As can be seen from the above test results, with the increase in the content of arecoline hydrobromide in the aerosol-forming substrate, the conversion rate tends to decrease, and even when the content of arecoline hydrobromide in the aerosol-forming substrate reaches 15%, the conversion rate is still higher than 50%. In addition, after the aerosol-forming substrates containing different contents of arecoline hydrobromide are atomized into aerosols, the experience of the smoker varies according to the content of arecoline salt in the aerosol. When the content of arecoline salt in the aerosol-forming substrate is lower than 0.2%, the smoker does not feel the satisfaction of inhaling arecoline, and with the increase in the content, the satisfaction increases, but when it exceeds 5%, the discomfort of inhaling arecoline salt begins to appear, and with the increase in the content under the experimental conditions, the discomfort gradually increases, and when the content exceeds 15%, the discomfort becomes unacceptable.

[0055] EMBODIMENT 3 Embodiment 3 of the present application provides an aerosol generating system, comprising an atomizing device and the aerosol-forming substrate according to embodiment 2, The atomizing device is configured to atomize the aerosol-forming substrate to form an aerosol.

[0056] In some embodiments, the atomizer is a heated atomizer.

[0057] In some embodiments, the nebulizer is an ultrasonic nebulizer.

[0058] In some embodiments, the aerosol-forming substrate comprises an arecoline salt, glycerin, and propanediol.

[0059] In some embodiments, the ultrasonic atomizer has an oscillation frequency greater than 1 MHz.

[0060] In some embodiments, the atomizing device is an air compression type atomizing device or a pressure type spray device.

[0061] In some embodiments, the aerosol-forming substrate comprises arecoline salt, ethanol, and water.

[0062] Embodiment 4 Embodiment 4 of the present application provides the use of arecoline salt in the manufacture of aerosol-generating products.

[0063] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with an acid for compounding. In some embodiments, the acid for compounding the arecoline salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0064] In some embodiments, the molar ratio of arecoline to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0065] In some embodiments, when manufacturing the aerosol-generating product, the mass percentage of the arecoline salt relative to the total mass of the raw materials of the aerosol-generating product is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, more preferably 2% - 10%, more preferably 2% - 5%, more preferably 2% - 4%, and more preferably 3% - 4%.

[0066] In some embodiments, objects added to the arecoline salt when producing the aerosol-generating product include atomizing agents, binders, and plant fibers.

[0067] In some embodiments, when producing the aerosol-generating product, the mass percentage of the atomizing agent relative to the total mass of the raw materials of the aerosol-generating product is 5% to 30%, preferably 10% to 30%, more preferably 10% to 25%, and even more preferably 15% to 25%.

[0068] In some embodiments, the atomizing agent is The additive is selected from at least one of 1,2-propanediol, 1,3-propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0069] In some embodiments, when producing the aerosol-generating product, the weight percentage of the binder, relative to the total weight of the raw materials of the aerosol-generating product, is between 1% and 20%, preferably between 1% and 15%, more preferably between 1% and 10%, more preferably between 3% and 10%, and even more preferably between 5% and 10%.

[0070] In some embodiments, the binding agent is The binder is selected from at least one of carboxymethylcellulose, hydroxypropylmethylcellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0071] In some embodiments, when producing the aerosol-generating product, the mass percentage of the plant fiber relative to the total mass of the raw materials of the aerosol-generating product is 40% to 80%, preferably 40% to 70%, more preferably 50% to 70%, even more preferably 50% to 65%, and even more preferably 50% to 60%.

[0072] In some embodiments, the plant fiber is The fiber is selected from at least one of areca nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, and palm pulp fiber.

[0073] In some embodiments, the object to which the arecoline salt is added further comprises a fragrance.

[0074] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0075] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0076] In some embodiments, the object to which the arecoline salt is added does not include tobacco leaf components.

[0077] In some embodiments, the method of making the aerosol-generating product comprises a papermaking process, a dry papermaking process, a thick pulping process, or a roll pressing process.

[0078] EMBODIMENT 5 Embodiment 5 of the present application provides an aerosol-generating product, the raw materials of which include arecoline salt, an atomizing agent, a binder and plant fiber.

[0079] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with an acid for compounding. In some embodiments, the acid for compounding the arecoline salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0080] In some embodiments, the molar ratio of arecoline to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0081] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, still more preferably 2% - 10%, still more preferably 2% - 5%, still more preferably 2% - 4%, and more preferably 3% - 4%.

[0082] In some embodiments, based on the total mass of the raw materials, the mass percentage of the atomizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, still more preferably 15% - 25%.

[0083] In some embodiments, the atomizing agent is The additive is selected from at least one of 1,2-propanediol, 1,3-propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0084] In some embodiments, the mass percentage of the binder relative to the total mass of the raw materials is 1% to 20%, preferably 1% to 15%, more preferably 1% to 10%, more preferably 3% to 10%, and even more preferably 5% to 10%.

[0085] In some embodiments, the binding agent is The binder is selected from at least one of carboxymethylcellulose, hydroxypropylmethylcellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, and shellac.

[0086] In some embodiments, the mass percentage of the plant fiber relative to the total mass of the raw material is 40% to 80%, preferably 40% to 70%, more preferably 50% to 70%, more preferably 50% to 65%, and even more preferably 50% to 60%.

[0087] In some embodiments, the plant fiber is The fiber is selected from at least one of areca nut fiber, wood pulp fiber, hemp pulp fiber, cotton pulp fiber, bagasse pulp fiber, bamboo pulp fiber, and palm pulp fiber.

[0088] In some embodiments, the ingredients further comprise a fragrance.

[0089] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Sweet Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone The composition is selected from at least one of the following: citronellol, concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0090] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0091] In some embodiments, the feedstock does not include tobacco components.

[0092] Example 1 The heated tobacco product is manufactured according to the following steps.

[0093] Step 1: Produce a sheet base material. Immerse the solid residue of the areca nut extract in water, set the water temperature to 60-80°C, soak for 0.5-2 hours, filter, pulp the filtered solid to obtain pulp, weigh out 50-70 parts of pulp and 3-10 parts of solid binder by weight, mix uniformly, send the mixed pulp to a paper machine to be molded, and dry to a moisture content of about 10-15% to obtain a sheet base material.

[0094] Here, the solid binder may be one or more of carboxymethylcellulose, hydroxypropylmethylcellulose, polyvinyl alcohol, rosin, xanthan gum, gum arabic, guar gum, chitosan, pectin, locust bean gum, starch, sodium alginate, shellac.

[0095] Step 2: Prepare the coating solution. Weigh out 1 to 50 parts of arecoline salt, 2 to 20 parts of fragrance, and 40 to 80 parts of atomizing agent by weight, and mix uniformly to obtain the coating solution.

[0096] Here, the atomizing agent is a mixture of glycerin and propanediol in a mixing ratio of 3 to 5:1.

[0097] Step 3: Coating the sheet substrate. Weigh out the coating solution obtained in step 2 according to 25% to 40% of the weight of the sheet substrate obtained in step 1, spray the coating solution onto the sheet substrate, and leave it at constant temperature and humidity for 40 to 60 hours to obtain a plant sheet containing arecoline salt.

[0098] Step 4: Producing a heat-not-burn cigarette The plant sheet obtained in step 3 is produced into a tobacco rod according to size, and the tobacco rod is connected to a filter to obtain a heat-not-burn cigarette containing arecoline salt.

[0099] The heated tobacco produced by the above manufacturing method was heated in an aerosol generating device (which uses resistance heating as the heating method), and the surface temperature of the heating element in the operating state was measured using infrared thermography. The measurement results are as shown in the table below. JPEG2025004112000003.jpg18169

[0100] As can be seen from these measurement results, the arecoline salt contained in tobacco can be atomized at 150°C to 250°C to generate an aerosol for inhalation.

[0101] When the normal heated tobacco was evaluated for suction and sensory quality, the heated tobacco produced by the above manufacturing method was able to produce the same effect as inhaling arecoline and chewing betel nuts, and had less irritation.

[0102] Embodiment 6 Embodiment 6 of the present application provides the use of arecoline salts in the preparation of the liquid composition of the filter capsule, where the filter capsule includes a brittle housing and the liquid composition, and the liquid composition is disposed within the brittle housing.

[0103] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with an acid for compounding.

[0104] In some embodiments, the acid for compounding the arecoline salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0105] In some embodiments, the molar ratio of arecoline to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0106] In some embodiments, the mass percentage of the arecoline salt relative to the total mass of the liquid composition is 0.2% to 15%, preferably 1% to 15%, more preferably 2% to 15%, even more preferably 2% to 10%, even more preferably 2% to 5%, even more preferably 2% to 4%, and more preferably 3% to 4%.

[0107] In some embodiments, objects added to the arecoline salt when preparing the liquid composition include an atomizing agent.

[0108] In some embodiments, the mass percentage of the atomizing agent relative to the total mass of the liquid composition is 5% to 30%, preferably 10% to 30%, more preferably 10% to 25%, and even more preferably 15% to 25%.

[0109] In some embodiments, the atomizing agent is The additive is selected from at least one of 1,2-propanediol, 1,3-propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0110] In some embodiments, the object to which the arecoline salt is added further comprises a fragrance.

[0111] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0112] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0113] In some embodiments, the substance to which the arecoline salt is added does not include nicotine and / or a nicotine salt.

[0114] In some embodiments, the filter capsule is embedded in the aerosol-generating product.

[0115] In some embodiments, the source of the aerosol-generating product does not include tobacco components.

[0116] EMBODIMENT 7

[0023] Embodiment 7 of the present application provides a filter capsule including a frangible housing and a liquid composition, the liquid composition being disposed within the frangible housing, Here, the liquid composition contains arecholine salt and an atomizing agent.

[0117] In some embodiments, the arecholine salt is obtained by neutralizing arecholine with an acid for compounding. In some embodiments, the acid for compounding of the arecholine salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0118] In some embodiments, the molar ratio of arecholine to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0119] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the arecholine salt is 0.2% - 15%, preferably 1% - 15%, more preferably 2% - 15%, still more preferably 2% - 10%, still more preferably 2% - 5%, still more preferably 2% - 4%, and more preferably 3% - 4%.

[0120] In some embodiments, based on the total mass of the liquid composition, the mass percentage of the atomizing agent is 5% - 30%, preferably 10% - 30%, more preferably 10% - 25%, still more preferably 15% - 25%.

[0121] In some embodiments, the atomizing agent is The additive is selected from at least one of 1,2-propanediol, 1,3-propanediol, glycerin, polyethylene glycol 200, polyethylene glycol 400, dipropylene glycol condensed ether, ethanol, water, triethyl citrate, triacetin, caprylic / capric triglyceride, isopropanol, orange oil, lemon oil, peppermint oil, palm oil, peanut oil, corn oil, and salad oil.

[0122] In some embodiments, the liquid composition further comprises a fragrance.

[0123] In some embodiments, the fragrance is cis-3,7-dimethyl-2,6-octadienol, trans-2-hexenol, linalool, benzyl alcohol, 1-hexanol, leaf alcohol, α-terpineol, citronellol, phenethyl alcohol, epoxydihydrolinalool, geraniol, isoamyl alcohol, octanol, hexanol, decanol, cinnamyl alcohol, heptanol, eugenol, maltol, ethyl maltol, thymol, isoeugenol, 2-methylbutyrate, malic acid, n-valeric acid, hexanoic acid, edible acetic acid, n-octanoic acid, berry acid, butyric acid, citric acid, propionic acid, 3-methylvaleric acid, isovaleric acid, isoamyl acetate, pentyl formate, geranyl formate, butyl formate, formic acid Benzyl, cis-3-hexenyl formate, γ-decalactone, δ-nonanelactone, γ-octalactone, γ-heptalactone, γ-undecanolactone, δ-dodecalactone, benzaldehyde, strawberry aldehyde, cinnamaldehyde, furfural, citral, acetaldehyde, 3-methylthiopropanal, natural 3-mercapto-2-methylpentanal, isobutyraldehyde, trans-2-octenal, trans-2-nonenal, trans-2-decenal, trans,trans-2,4-heptadienal, 2,5-dimethylpyrazine, 2-acetylfuran, 2-ethyl-3(5 or 6)-dimethylpyrazine, 2,3,5,6-tetramethylpyrazine, 2,3,5-Trimethylpyrazine, 2-Acetylpyrazine, Acetophenone, β-Ionone, Damascenone No. 2 (Firmenich), Butanedione, α-Ionone, Acetoin (Acetyl Methyl Carbinol), Sulcatone, Vanillin, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, Anisole, Cedrol Methyl Ether, Methyl-2-Methyl-3-Furyl Disulfide, Wintergreen Oil, Clove Bud Oil, 10x Orange Oil, Rosewood Oil, Geranium Oil, Bitter Almond Oil, Clove Basil Oil, Ethyl Vanillin, Dihydrocoumarin, Raspberry Ketone, At least one of the following may be selected: concentrated vanillin, torresinoids, peruvian extract, oak extract, espresso supercritical extract (water soluble), cocoa extract, coffee tincture, angelica polyclada tincture, pandan extract, vanilla extract, labdanum concrete, orris oil / orris root absolute, jasmine concrete, wood moss concrete (amber scent), tamarind extract, zimbabwe tobacco extract, tobacco essential oil, burley tobacco extract, tobacco leaf absolute A, roasted tobacco leaf top note extract, sun-dried tobacco leaf top note extract.

[0124] In addition, the air freshener is not limited to the above, and any air freshener that complies with the FEMA number or CAS number is applicable.

[0125] In some embodiments, the liquid composition does not include nicotine and / or nicotine salts.

[0126] EMBODIMENT 8 Embodiment 8 of the present application provides an aerosol-generating product comprising the filter capsule described in embodiment 7.

[0127] In some embodiments, the source of the aerosol-generating product does not include tobacco components.

[0128] In this embodiment, the aerosol-generating product can be manufactured by a papermaking method, a dry papermaking method, a thick pulping method, or a roll press method. Specifically, the raw materials and manufacturing steps of the aerosol-generating product may refer to the contents described in the above embodiment.

[0129] The filter capsule is embedded in the filter portion (not limited to this location) of the heated tobacco product using filter rod embedding technology (not limited to this technology), and when in use, the smoker can inhale substances such as arecoline by applying pressure to break the filter capsule.

[0130] In this embodiment, the components of the brittle housing and the manufacturing process thereof, and the manufacturing process of the filter capsule are not particularly limited, and techniques known to those skilled in the art can be used.

[0131] Example 1 A liquid composition contained in a filter capsule is prepared according to the following formula:

[0132] Arecoline salt 10wt%, Caprylic / Capric Triglyceride 80wt%, Menthol 10wt%.

[0133] Preparation method: Weigh out the arecoline salt in the above-mentioned amount, add caprylic / capric triglyceride and menthol while stirring, and mix uniformly.

[0134] When the inhalation and sensory quality were evaluated for a heated cigarette containing the filter capsule of Example 1 and a heated cigarette without a filter capsule, it was found that the heated cigarette containing the filter capsule of Example 1 produced an effect similar to that of inhaling arecoline and chewing betel nut, and was less irritating.

[0135] EMBODIMENT 9 Embodiment 9 of the present application provides the use of arecoline salt in the manufacture of chewing gum.

[0136] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with an acid for compounding. In some embodiments, the acid for compounding the arecoline salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0137] In some embodiments, the molar ratio of arecoline to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0138] In some embodiments, when manufacturing the chewing gum, the mass percentage of the arecoline salt relative to the total mass of the raw materials of the chewing gum is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, still more preferably 0.02% - 1%, still more preferably 0.1% - 1%, still more preferably 0.2% - 1%, still more preferably 0.4% - 1%.

[0139] In some embodiments, when manufacturing the chewing gum, the object added to the arecoline salt includes a gum base.

[0140] In some embodiments, when producing the chewing gum, the mass percentage of the gum base relative to the total mass of the raw materials of the chewing gum is 20% to 75%, preferably 20% to 70%, more preferably 20% to 60%, even more preferably 20% to 50%, even more preferably 25% to 50%, even more preferably 30% to 50%, even more preferably 35% to 50%, and even more preferably 35% to 45%.

[0141] In some embodiments, the object to which the arecoline salt is added further comprises a sweetener.

[0142] In some embodiments, the sweetener is The sugar is selected from at least one of white sugar, crystal sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame, sucralose, stevioside, and neotame. In some embodiments, when producing the chewing gum, the mass percentage of the sweetener relative to the total mass of the raw materials of the chewing gum is 20% to 75%, preferably 20% to 70%, more preferably 20% to 60%, even more preferably 20% to 50%, even more preferably 25% to 50%, even more preferably 25% to 40%, even more preferably 25% to 35%, and even more preferably 30% to 35%.

[0143] In some embodiments, the object to which the arecoline salt is added further comprises a filler material.

[0144] In some embodiments, the filler comprises: The calcium carbonate is selected from at least one of sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, and sodium dihydrogen phosphate.

[0145] In some embodiments, when producing the chewing gum, the mass percentage of the filler relative to the total mass of the raw materials of the chewing gum is 0.03% to 23%, preferably 0.03% to 20%, more preferably 0.03% to 15%, even more preferably 0.03% to 10%, even more preferably 0.5% to 10%, even more preferably 1% to 10%, even more preferably 1.5% to 10%, even more preferably 2% to 8%, and even more preferably 2% to 6%.

[0146] In some embodiments, the object to which the arecoline salt is added further comprises a flavor enhancer.

[0147] In some embodiments, the seasoning comprises: Choose from at least one of the following: mint, spearmint, cinnamon, ice chips, and essence.

[0148] EMBODIMENT 10 A tenth embodiment of the present application provides a chewing gum, the ingredients of which include arecoline salt and a gum base.

[0149] In some embodiments, the arecoline salt is obtained by neutralizing arecoline with a compounding acid. In some embodiments, the arecoline salt is formulated with at least one acid selected from the group consisting of formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, and histidine.

[0150] In some embodiments, the molar ratio of the arecoline to the acid for compounding is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, and even more preferably 0 < n ≤ 2.

[0151] In some embodiments, based on the total mass of the raw materials, the mass percentage of the arecoline salt is 0.02% - 2%, preferably 0.02% - 1.6%, more preferably 0.02% - 1.2%, still more preferably 0.02% - 1%, still more preferably 0.1% - 1%, still more preferably 0.2% - 1%, and even more preferably 0.4% - 1%.

[0152] In some embodiments, based on the total mass of the raw materials, the mass percentage of the gum base is 20% - 75%, preferably 20% - 70%, more preferably 20% - 60%, still more preferably 20% - 50%, still more preferably 25% - 50%, still more preferably 30% - 50%, still more preferably 35% - 50%, and even more preferably 35% - 45%.

[0153] In some embodiments, the raw materials further include a sweetening agent.

[0154] In some embodiments, the sweetening agent is selected from at least one of granulated sugar, rock sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame, sucralose, stevioside, and neotame.

[0155] In some embodiments, based on the total mass of the raw materials, the mass percentage of the sweetening agent is 20% - 75%, preferably 20% - 70%, more preferably 20% - 60%, still more preferably 20% - 50%, still more preferably 25% - 50%, still more preferably 25% - 40%, still more preferably 25% - 35%, and even more preferably 30% - 35%.

[0156] In some embodiments, the ingredients further comprise a filler.

[0157] In some embodiments, the filler comprises: The calcium carbonate is selected from at least one of sodium carbonate, sodium bicarbonate, potassium carbonate, calcium carbonate, dicalcium phosphate, and sodium dihydrogen phosphate.

[0158] In some embodiments, the mass percentage of the filler relative to the total mass of the raw materials is 0.03% to 23%, preferably 0.03% to 20%, more preferably 0.03% to 15%, even more preferably 0.03% to 10%, even more preferably 0.5% to 10%, even more preferably 1% to 10%, even more preferably 1.5% to 10%, even more preferably 2% to 8%, and even more preferably 2% to 6%.

[0159] In some embodiments, the ingredients further comprise a seasoning.

[0160] In some embodiments, the seasoning comprises: Choose from at least one of the following: mint, spearmint, cinnamon, ice chips, and essence.

[0161] Example 1 A chewing gum is manufactured according to the following recipe:

[0162] Gum base 54wt%, powdered sugar 23wt%, glucose syrup 14wt%, potassium carbonate 4wt%, mint flavoring 3wt%, menthol 1wt%, arecoline salt 1wt%.

[0163] Manufacturing method: The gum base is heated to 70-105°C, then mixed in a mixer, powdered sugar is added, the temperature is lowered to 60-80°C, buffer pairs, additives, glucose syrup, and arecoline salt are added, and finally the gum base is made into tablets and shaped to produce the finished product.

[0164] Example 2 Xylitol chewing gum is manufactured according to the following formula:

[0165] Gum base 54wt%, xylitol 23wt%, non-sucrose 14wt%, potassium carbonate 4wt%, mint flavoring 3wt%, menthol 1wt%, arecoline salt 1wt%.

[0166] Manufacturing method: The gum base is heated to 70-105℃, then mixed in a mixer, xylitol and non-sucrose are added, and the temperature is lowered to 60-80℃. Buffer pairs, additives, and arecoline salt are then added, and the gum base is made into tablets and shaped to produce the finished product.

[0167] The chewing gum produced by the above-mentioned method and a normal chewing gum were evaluated for edible and sensory qualities, and it was found that the chewing gum produced by the above-mentioned method can produce the same effect as chewing betel nut, is less irritating, and has a good texture. The chewing gum does not contain lime powder or cellulose, so it can avoid problems such as abrasion and irritation of the oral mucosa and induction of oral diseases that occur when chewing betel nut.

[0168] EMBODIMENT 11 Embodiment 11 of the present application provides the use of arecoline salt in the preparation of beverages.

[0169] In some embodiments, the arecholine salt is obtained by neutralizing arecholine with a compounding acid. In some embodiments, the compounding acid for the arecholine salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0170] In some embodiments, the molar ratio of arecholine to the compounding acid is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, more preferably 0 < n ≤ 5, more preferably 0 < n ≤ 3, more preferably 0 < n ≤ 2.

[0171] In some embodiments, when preparing the beverage, the mass percentage of the arecholine salt relative to the total mass of the beverage is 0.01% - 0.5%, preferably 0.01% - 0.4%, more preferably 0.01% - 0.3%, more preferably 0.01% - 0.2%, more preferably 0.05% - 0.2%.

[0172] In some embodiments, when preparing the beverage, the object added to the arecholine salt contains water.

[0173] In some embodiments, when preparing the beverage, the mass percentage of water relative to the total mass of the beverage is 75% - 90%.

[0174] In some embodiments, the subject matter added to the arecoline salt when preparing the beverage further comprises a functional ingredient.

[0175] In some embodiments, the functional ingredient is: The active ingredient is selected from at least one of monk fruit concentrate, natural menthol, licorice concentrate, honeysuckle concentrate, chrysanthemum extract, kudzu root extract, and loquat puree.

[0176] In some embodiments, the mass percentage of the functional ingredient is between 0.5% and 2% based on the total mass of the beverage.

[0177] In some embodiments, the subject matter added to the arecoline salt when preparing the beverage further comprises an acidity regulator.

[0178] In some embodiments, the acidity regulator is The acid is selected from at least one of tartaric acid, malic acid, citric acid, and sodium citrate.

[0179] In some embodiments, when the beverage is prepared, the mass percentage of the acidity regulator is between 0.1% and 5% based on the total mass of the beverage.

[0180] In some embodiments, the objects to which the arecoline salt is added when preparing the beverage further include a sweetener.

[0181] In some embodiments, the sweetener is The sugar is selected from at least one of white sugar, crystal sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame, sucralose, stevioside, and neotame.

[0182] In some embodiments, when the beverage is prepared, the mass percentage of the sweetener is between 0.5% and 5% based on the total mass of the beverage.

[0183] In some embodiments, the subject matter added to the arecoline salt when preparing the beverage further comprises an antioxidant.

[0184] In some embodiments, the antioxidant is At least one of ascorbic acid, sodium erythorbate, vitamin C, and vitamin E is selected.

[0185] In some embodiments, when the beverage is prepared, the weight percentage of the antioxidant is between 0.05% and 0.15%, based on the total weight of the beverage.

[0186] In some embodiments, the objects added to the arecoline salt when preparing the beverage further include a preservative.

[0187] In some embodiments, the preservative is It is selected from at least one of sodium benzoate, sodium sorbate, and potassium sorbate.

[0188] In some embodiments, when the beverage is prepared, the mass percentage of the preservative is 0.01% to 0.05%, based on the total mass of the beverage.

[0189] In some embodiments, the objects added to the arecoline salt when preparing the beverage further include edible essences.

[0190] In some embodiments, when the beverage is prepared, the mass percentage of the edible essence is between 0.5% and 5% based on the total mass of the beverage.

[0191] EMBODIMENT 12 Embodiment 12 of the present application provides a beverage, the raw materials of which include arecholine salt and water. In some embodiments, the arecholine salt is obtained by neutralizing arecholine with a compounding acid. In some embodiments, the compounding acid for the arecholine salt is at least one selected from formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, histidine.

[0192] In some embodiments, the molar ratio of arecholine to the compounding acid is n, where the value range of n is 0 < n ≤ 10, preferably 0 < n ≤ 8, more preferably 0 < n ≤ 6, still more preferably 0 < n ≤ 5, still more preferably 0 < n ≤ 3, still more preferably 0 < n ≤ 2.

[0193] In some embodiments, based on the total mass of the beverage, the mass percentage of the arecholine salt is 0.01% - 0.5%, preferably 0.01% - 0.4%, more preferably 0.01% - 0.3%, still more preferably 0.01% - 0.2%, still more preferably 0.05% - 0.2%.

[0194] In some embodiments, based on the total mass of the beverage, the mass percentage of the water is 75% - 90%.

[0195] In some embodiments, the raw materials further include functional components.

[0196] In some embodiments, the functional components are The active ingredient is selected from at least one of monk fruit concentrate, natural menthol, licorice concentrate, honeysuckle concentrate, chrysanthemum extract, kudzu root extract, and loquat puree.

[0197] In some embodiments, the weight percentage of the functional ingredient is 0.5% to 2%.

[0198] In some embodiments, the ingredient further comprises an acidity adjuster.

[0199] In some embodiments, the acidity regulator is The acid is selected from at least one of tartaric acid, malic acid, citric acid, and sodium citrate.

[0200] In some embodiments, the weight percentage of the acidity regulator is between 0.1% and 5%.

[0201] In some embodiments, the ingredient further comprises a sweetener.

[0202] In some embodiments, the sweetener is The sugar is selected from at least one of white sugar, crystal sugar, sucrose, maltose, corn syrup, glucose syrup, fructose, maltodextrin, polydextrose, xylitol, sorbitol, maltitol, erythritol, aspartame, acesulfame, sucralose, stevioside, and neotame.

[0203] In some embodiments, the weight percentage of the sweetener is between 0.5% and 5%.

[0204] In some embodiments, the ingredient further comprises an antioxidant.

[0205] In some embodiments, the antioxidant is At least one of ascorbic acid, sodium erythorbate, vitamin C, and vitamin E is selected.

[0206] In some embodiments, the weight percentage of the antioxidant is between 0.05% and 0.15%.

[0207] In some embodiments, the ingredients further comprise a preservative.

[0208] In some embodiments, the preservative is It is selected from at least one of sodium benzoate, sodium sorbate, and potassium sorbate.

[0209] In some embodiments, the weight percentage of the preservative is between 0.01% and 0.05%.

[0210] In some embodiments, the ingredients further comprise an edible essence.

[0211] In some embodiments, the mass percentage of the edible essence is between 0.5% and 5%.

[0212] Example 1 A beverage is prepared according to the following formula:

[0213] Arecoline salt 0.1wt%, water 88wt%, honeysuckle concentrate juice 1wt%, licorice concentrate juice 1wt%, citric acid 2wt%, sodium citrate 2wt%, steviol glycosides 3wt%, vitamin C 0.05wt%, sodium sorbate 0.05wt%, edible essence 2.8wt%.

[0214] Preparation method: thoroughly mix arecoline salt with water, honeysuckle juice concentrate, licorice juice concentrate, citric acid, sodium citrate, steviol glycosides, vitamin C, sodium sorbate, and edible essence to prepare a beverage.

[0215] The beverage prepared by the above-mentioned method retains various nutrients found in honeysuckle and licorice that are beneficial to the human body, is rich in ingredients such as arecoline and areca nut polyphenols, has a good texture, and has the effects of invigorating the spleen, nourishing qi, clearing fever and detoxifying, expelling phlegm, relieving coughs, and relieving acute pain.

[0216] This document discloses the present application using examples, including the best mode, to enable any person skilled in the art to make and use the present application. The patentable scope of this application is limited by the claims, and may include other examples that occur to those skilled in the art. Such other examples are intended to be within the scope of the claims if they have structural elements that do not differ from the literal language of the claims, or if they include equivalent structural elements that do not differ substantially from the literal language of the claims. Unless inconsistent, all content cited herein is incorporated by reference.

Claims

1. 1. A betel nut flavored product, the product being an aerosol-forming substrate, the aerosol-forming substrate comprising an arecoline salt, and a mass percentage of the arecoline salt relative to a total mass of the aerosol-forming substrate is between 1% and 10%.

2. 2. The product of claim 1, wherein the mass percentage of the arecoline salt relative to the total mass of the aerosol-forming substrate is between 2% and 10%, or between 2% and 5%, or between 2% and 4%, or between 3% and 4%.

3. 1. A betel nut flavored product, the product being a chewing gum, the chewing gum comprising an arecoline salt, the mass percentage of the arecoline salt being 0.05% to 2% based on the total mass of ingredients of the chewing gum.

4. 4. The product of claim 3, wherein the weight percentage of the arecoline salt is from 0.1% to 1%, or from 0.2% to 1%, or from 0.4% to 1%, based on the total weight of the chewing gum ingredients.

5. A betel nut flavored product, the product being a filter capsule, the filter capsule containing a liquid composition, the liquid composition containing an arecoline salt, and the mass percentage of the arecoline salt relative to the total mass of the liquid composition is 1% to 10%.

6. 6. The product of claim 5, wherein the weight percentage of the arecoline salt is between 2% and 10%, or between 2% and 5%, or between 2% and 4%, or between 3% and 4%, relative to the total weight of the liquid composition.

7. The product according to any one of claims 1 to 6, wherein the arecoline salt is obtained by neutralizing arecoline with a compounding acid.

8. The compounding acid of the arecoline salt is 8. The product of claim 7, which is at least one of the following: formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, proline, tryptophan, serine, tyrosine, cysteine, methionine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine, and histidine.

9. 8. The product of claim 7, wherein the molar ratio of arecoline to the blending acid is n, where the range of values ​​of n is 0<n≦10, or 0<n≦8, or 0<n≦6, or 0<n≦5, or 0<n≦3, or 0<n≦2.

10. A product according to any one of claims 1 to 6, wherein the arecoline salt is arecoline hydrobromide and / or arecoline benzoate.

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