The invention discloses a preparation method of Azilsartan tablets and belongs to the technical field of medicine. The preparation method comprises the following steps: 1, micronizing the Azilsartan, controlling D90 less than 15 micrometers, and conducting weighing according to formula dosage; 2, screening lactose monohydrate with a 60-mesh screen, and conducting weighing according to formula dosage; 3, screening a disintegrating agent and diluent with a 60-mesh screen respectively, and conducting weighing according to formula dosage; 4, mixing the auxiliary ingredients in the step 1, 2 and 3, adding solubilizer, conducting mixing, and screen the mixture with a 60-mesh screen; mixing the auxiliary ingredients uniformly, and adding adhesion agents for soft materials; conducting sieving, granulating, drying and arranging, adding lubricating agents, mixing the mixture uniformly, and tabletting. According to the preparation method, by controlling the particle diameter of the Azilsartan and the weight ratio between the Azilsartan and the lactose monohydrate and the varieties and adjusting the proportion of the disintegrating agents, the lubricating agents, the diluent, the solubilizer and the binding agents, the problem of dissolution rate can be solved, and the problem of external consistent dissolution is solved as well.