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208 results about "Profile analysis" patented technology

Methods and compositions for detecting rare cells from a biological sample

The present invention provides methods and compositions for isolating and detecting rare cells from a biological sample containing other types of cells. In particular, the present invention includes a debulking step that uses a microfabricated filters for filtering fluid samples and the enriched rare cells can be used in a downstream process such as identifies, characterizes or even grown in culture or used in other ways. The invention also include a method of determining the aggressiveness of the tumor or of the number or proportion of cancer cells in the enriched sample by detecting the presence or amount of telomerase activity or telomerase nucleic acid or telomerase expression after enrichment of rare cells. This invention further provides an efficient and rapid method to specifically remove red blood cells as well as white blood cells from a biological sample containing at least one of each of red blood cells and white blood cells, resulting in the enrichment of rare target cells including circulating tumor cells (CTC), stromal cells, mesenchymal cells, endothelial cells, fetal cells, stem cells, non-hematopoietic cells etc from a blood sample. The method is based upon combination of immuno-microparticles (antibody coated microparticles) and density-based separation. The final enriched target cells can be subjected to a variety of analysis and manipulations, such as flowcytometry, PCR, immunofluorescence, immunocytochemistry, image analysis, enzymatic assays, gene expression profiling analysis, efficacy tests of therapeutics, culturing of enriched rare cells, and therapeutic use of enriched rare cells. In addition, depleted plasma protein and white blood cells can be optionally recovered, and subjected to other analysis such as inflammation studies, gene expression profiling, etc.
Owner:AVIVA BIOSCI

Programmable phase velocity in an ultrasonic imaging system

An ultrasonic image scanning system for scanning an organic object includes a beam former that provides a phase velocity adjustment function for producing an ultrasonic image with a programmable phase velocity. The ultrasonic image scanning system further includes a beam profile analysis function for calculating an optimal phase velocity with a user controller to adjust the phase velocity until a scan image of best image quality is achieved. Alternately, the system may provide an automatic phase velocity-scanning controller for automatically scanning through a range of phase velocities and selecting a best phase velocity generating a scanning image of a best quality. The system further includes a region of interest (ROI) controller for a user to select a region for scanning with a specific focal area for optimizing the phase velocity. The system may further provide a maximum gradient analyzer for selecting an image of a best quality in optimizing the phase velocity. A digital controller may also provide a real time programmable control by applying different control algorithms with combination of phase velocity and attenuation adjustment. A hardness computational processor is implemented to determine a tissue hardness using the phase velocity and in combination with the attenuation parameter.
Owner:SONOWISE

Building facade three-dimensional reconstruction method based on knapsack type three-dimensional laser point cloud data

The invention discloses a building facade three-dimensional reconstruction method based on knapsack type three-dimensional laser point cloud data, and relates to the technical field of geographic information. The method comprises the following steps: S1, acquiring building point cloud data; S2, automatically extracting building facade point cloud data; S3, automatically segmenting the single buildings; S4, acquiring a geometric position boundary of the building facade; and S5, building facade three-dimensional reconstruction. A point cloud filtering algorithm based on voxel projection densityis adopted to effectively filter non-building targets such as the ground and vegetation while a relatively complete building target is reserved, and then automatic segmentation of a single building isrealized by utilizing an image global search and profile analysis method. An RANSAC algorithm is used to carry out facade automatic segmentation and redundant facade elimination on the single building point cloud to obtain a building facade geometric position boundary; and the two-dimensional boundary line is used to constrain the original point cloud data and an RANSAC algorithm is combined tocarry out facade three-dimensional boundary straight line fitting so as to obtain a building facade geometric frame model.
Owner:SUZHOU IND PARK SURVEYING MAPPING & GEOINFORMATION CO LTD

Small sand body boundary identification method and small sand body space quantitative description method

The invention discloses a small sand body boundary identification method and a small sand body space quantitative description method. The small sand body boundary identification method comprises the following steps: summarizing the development rules and scale of a sand body according to the geological situation of a region; summarizing the seismic response characteristics of a reservoir and carrying out seismic profile identification and interpretation through seismic forward modeling; processing earthquake in a frequency division way, extracting seismic attributes of different frequency bands, and adopting known well data analysis to preferably select seismic attributes better corresponding to the reservoir and the sand body; and finely describing the sand body by comprehensively adopting the geological rules, sand body seismic response characteristics and frequency-division seismic attribute analysis. The small sand body space quantitative description method comprises the steps of drawing the boundary of a sand body and determining a favorable area of a reservoir by the above method, and quantitatively describing the spatial shape of the sand body through well logging constrained inversion. The boundary of a described small sand body is accurate and quick to describe, and the accuracy of reservoir predication can be improved.
Owner:CHINA PETROLEUM & CHEM CORP +1

Flood forecasting method based on water level sample

The invention relates to a flood forecasting method based on a water level sample. The flood forecasting method is characterized by comprising the following steps of S01: simulating a runoff formation process by adopting a water tank mode, and abstracting the process of converting rainfall into runoff into a relation between the water storage and the outflow of a drainage basin; S02: establishing a function relation between the flow and the water level, performing function fitting on the water level and the average velocity of the cross section first by adopting a zero-crossing power function, and then establishing a relation between the water level of the cross section and the flow; S03: obtaining a relation between the rainfall capacity and the outflow water level; S04: continuously improving the accuracy of a hydrological model by comparing an obtained outflow water level process with an actually measured water level value and adjusting parameters of the hydrological model; S05: inputting the rainfall capacity and the surface evaporation quantity of the upstream drainage basin by aiming at the calibrated hydrological model, so as to obtain the downstream outlet water level process, judging whether a forecasting area is flooded according to a water level peak value, and analyzing the lag time between a rainfall peak and a flood peak according to existing water level rainfall data, so as to determine the peak time.
Owner:连承锴

System for measuring scattering function of water body wide-angle body

The invention provides a measuring system for a wide-angle volume scattering function of water body. The structure of the invention mainly comprises: a measuring device for volume scattering function of water body and a data acquisition circuit of the measuring system, wherein, the measuring device for volume scattering function of water body is composed of a light source, a transmitted light detecting probe and a plurality of scattered light detecting probes which are equipped on different positions of the toroidal radius of a semi-toroidal frame respectively so as to detect the transmitted light and scattering light signals from different directions ranging from 0 DEG to 180 DEG., the light source, the transmitted light detecting probe and all scattered light detecting probes are connected with the data acquisition circuit of the measuring system by a watertight cable, and the data acquisition and storage process of the measuring device is controlled by the data acquisition circuit of the measuring system. The measuring system can measure the transparency of water body and the volume scattering function of water body in different directions ranging from 0 DEG to 180 DEG synchronously both on-line and on-site, and can be used for profile analysis on scattering and inherent optical properties of water body on-site.
Owner:SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI

Method for diagnosing internal damage of cereal grains based on micro-CT (computed tomography) technology

The invention relates to a method for diagnosing internal damage of cereal grains based on a micro-CT (computed tomography) technology. Micro-CT equipment is utilized for performing X-ray micro-CT scanning on unhulled cereal grains, a profile scanning sequence image of a damaged grain is obtained, threshold segmentation is utilized for processing the profile scanning sequence image, three-dimensional images of a grain body and cracks are reconstructed respectively, calculation is performed with a volumetric reconstruction method to obtain the volume of a grain body target and the volume of the cracks, the internal damage degree of the grain is measured based on the volume of the grain body target and the volume of the cracks, the three-dimensional image of the cereal grain body is subjected to multi-angle profile analysis and crack three-dimensional image analysis, a distribution situation of the cracks in the cereal grain is visually represented, and the number and sectional area of cracks are quantified. Due to the adoption of the technical scheme, a structure for analyzing the internal damage degree of the cereal grains is obtained, a three-dimensional internal result image of a sample is further obtained, and the internal damage degree of the cereal grains can be quickly and accurately identified without removing cereal grain hulls and changing shapes and internal structures of the cereal grains.
Owner:JIANGSU UNIV

Completion design method by bottom water reservoir horizontal well segregated water control

InactiveCN102953713AExtended oil recovery periodMeet the needs of rapid completion designFluid removalBreakthrough timeData information
A completion design method by bottom water reservoir horizontal well segregated water control includes the steps of determining horizontal well water control well sections by analyzing and determining the well sections needing to be packed during segregated completion according to collected data information, and defining final water control well sections; performing optimization design of a segregated scheme by determining reasonable segregated number and segregated length according to the final water control well sections; performing optimization design of a completion scheme by taking minimum difference of water breakthrough time of the water control well sections of the segregated scheme and minimum completion total additional percolating resistance as a principle, optimizing to obtain reasonable liquid production capacity and additional resistance values of the water control well sections, and determining throttling passage parameters of the water control well sections; and performing horizontal well segregated water control completion construction by performing construction of the water control completion scheme according to the reasonable liquid production capacity, the additional resistance values and the throttling passage parameters, and controlling the liquid production capacity of each water control well section to achieve water control and oil stabilization.
Owner:CHINA UNIV OF PETROLEUM (EAST CHINA)

Seismic source inversion method based on micro seismic data and SPSA optimization algorithm

The invention relates to a seismic source inversion method based on micro seismic data and an SPSA optimization algorithm. The method comprises the following steps: building a horizontal layered velocity model according to the analysis of logging data and underground rock property data; fast modeling a micro seismic event, adjusting the angle of ray in a dichotomy approach to optimize the ray tracking path, calculating the first-arrival travel time, and then calculating the travel time difference between two adjacent detectors; adding the travel time difference to random perturbation as an observed value; using an SPSA algorithm to calculate the first-arrival travel time difference in the same way based on the location of a micro seismic source obtained through iterative updating, constantly optimizing the location of the seismic source by fitting calculated data and the observed value, and checking the difference between the calculated data and the observed value; if the precision is satisfied or the maximum number of iterations is achieved, stopping updating, outputting a result, and completing positioning; or, continuing next iteration. By calculating out a micro seismic event source rapidly and efficiently, the accuracy of seismic source locating is improved.
Owner:CHINA UNIV OF PETROLEUM (EAST CHINA)
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