Multi-mode ionization source and application thereof

An ionization source and multi-mode technology, applied in the direction of ion source/gun, circuit, discharge tube, etc., can solve the problems of poor ionization ability of non-polar or weak polar compounds, low analytical sensitivity, and inability to obtain molecular data, etc. Achieve the effects of small size, fast analysis speed, and avoid the process of disassembly and replacement
CN107154337AActive Publication Date: 2017-09-12INST OF CHEM CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF CHEM CHINESE ACAD OF SCI
Publication Date
2017-09-12

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Abstract

The invention discloses a multi-mode ionization source, a multi-mode ionization source system, a mass spectrum, and a method for analyzing a to-be-tested sample with the mass spectrum. The multi-mode ionization source comprises a capillary tube, an internal electrode, an insulating tube, an external electrode, a tee fitting, an insulating sleeve, a metal ring, a conductive member and a regulating member, wherein the outlet of the internal electrode in the axial direction is located between the insulating tube and the outlet of the outer electrode. The multi-mode ionization source can be easily switched between two modes of electrospray ionization and plasma ionization, which can effectively improve the efficiency of analysis and detection, avoid the complicated dismounting process of the ionization source and realize the highly sensitive detection of components in the complex sample. The multi-mode ionization source is especially suitable for a variety of polar and non-polar small molecule compounds.
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Description

technical field

[0001] The invention relates to a multi-mode ionization source and its application, in particular to a multi-mode ionization source, a multi-mode ionization source system, a mass spectrometer, and a method for analyzing samples to be measured by using the mass spectrometer. Background technique

[0002] Atmospheric desorption ionization mass spectrometry (Ambient mass spectrometry) can directly ionize the sample rapidly under atmospheric pressure (the sample can be subjected to no pretreatment or minimal pretreatment), so as to achieve high-throughput and high-specificity mass spectrometry or quantitative analysis. In recent years, atmospheric pressure desorption ionization mass spectrometry has attracted wide attention. At present, dozens of atmospheric pressure desorption ionization techniques and multi-ionization source coupling techniques have been developed. These techniques are now widely used in food safety, drug analysis, and environmental analysis. ...

Claims

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