39 results about "Tumor surgery" patented technology

The present invention relates to the technical field of medical drainage tubes, in particular to an abdominal drainage device for tumor surgery. The abdominal drainage device comprises a negative pressure drainage device, wherein a control apparatus is provided on the negative pressure drainage device; a negative pressure drainage assembly is provided at the front end of the negative pressure drainage device; a drainage connecting tube is fixedly mounted at a drainage tube connection end of the negative pressure drainage assembly; and an abdominal drainage tube assembly is provided at one end of the drainage connecting tube. The beneficial effects are as follows: by means of designing a rigid adjustment branch tube below an abdominal drainage main tube, and cooperatively designing an adjustment fixing ring and an adjustment fixing assembly, a pushing spacer is moved to make a movable adjustment tube rotate as a whole, and then the pushing spacer is pressed to pull a tightening line, such that a gate plate presses adjustment bumps, shifting hollow spherical tubes above the rigid adjustment branch tube and deflecting hollow spherical tubes below the rigid adjustment branch tube, thereby driving the adjustments of the positions of a rigid connection branch tube and an abdominal drainage branch tube by means of the deflection below the rigid adjustment branch tube, and facilitating the adjustments of drainage positions.

The embodiment of the invention discloses a gynecological malignant tumor postoperative home nursing and system. The method comprises the following steps: determining patient information corresponding to a patient to be nursed, wherein the patient information comprises physiological data and malignant tumor postoperative data; determining a real-time health state of the to-be-nursed patient based on the physiological data and the malignant tumor postoperative data; inputting the real-time health state into a preset nursing method atlas database, and determining a home nursing method corresponding to the patient to be nursed based on the preset nursing method atlas database; and obtaining personalized data of the to-be-nursed patient, and correcting the home nursing method based on the personalized data to obtain a target home nursing method corresponding to the to-be-nursed patient. According to the application, the scientificity, safety and patient compliance of home care can be remarkably improved, and rehabilitation support which has higher clinical value and meets individual requirements is provided for malignant tumor postoperative patients.

The utility model discloses a novel injection device capable of adjusting injection depth. The novel injection device comprises two injection tubes with different lengths, a propelling mechanism arranged on the inner sides of the injection tubes, and an injection mechanism arranged on one side of the propelling mechanism, the injection tube is arranged in a straight tube shape with one sealed end and is hollow, threads are formed in the injection tube, and the propelling mechanism and the injection mechanism are both arranged on the inner side of the injection tube; the propelling mechanism comprises a propelling block, a rotating ring in sliding connection with the propelling block, and a first spring fixedly connected with the propelling block; the two ends of the first spring are fixedly connected with the injection tube and the pushing block respectively, and a fixing piece is arranged in the pushing block. The injection mechanism comprises a base, an injection part arranged on the base and a medicine bin in threaded connection with the inner side of the injection tube; the base is fixedly connected to one side of the pushing block; by means of rotation of the traction shaft in the injection part, the withdrawing effect can be achieved by rotating the traction shaft in the malignant tumor operation process.

The invention relates to a medical instrument for gynecologic operation, in particular to a uterus traction device capable of avoiding tumor cell diffusion and a using method thereof.The traction device comprises a bag, the bag is provided with a closed end used for wrapping the bottom of the uterus and an open end used for facing the cervix uteri opening, and the bag is provided with an opening. The open end is provided with an adjusting and tightening mechanism, the cervix uteri, the uterus body and the double accessories of the cervix uteri and the uterus body can be wrapped in the bag by pulling the open end, and then the open end is tightened through the adjusting and tightening mechanism. A wrapping path in the direction from the bottom of the uterus to the cervix uteri opening is adopted, it is ensured that the uterus and contents of the uterus are completely wrapped and isolated in the bag by tightening the opening end, the operation concept that isolation is carried out in advance is achieved, the operation view is protected in the whole process, and tumor-free traction in the operation process is facilitated; in addition, the risks of incision planting and abdominal cavity spreading in malignant tumor surgery can be greatly reduced, the possibility of tumor cell spreading is avoided, and iatrogenic injury is reduced.

The application discloses a radio-positioning glove and belongs to the technical field of medical devices. The glove comprises an elastic inner layer glove and a non-elastic outer layer glove sleeved on the outer side of the inner layer glove, and both of them are made of X-ray non-developing material. The surface of the non-elastic outer layer glove is provided with a surface developing coordinate grid formed by developing material, and physical mark holes penetrating through the outer layer and the inner layer along the thickness direction are arranged at the intersection points of the longitudinal and transverse coordinate lines of the grid. The inner layer glove and the outer layer glove are connected through magic tape at the hand insertion end, and the remaining parts are in a superimposed and relatively slidable state. The application effectively eliminates the interference of the sliding of the soft tissue and the skin of the hand on the positioning accuracy by using the rigid constraint of the non-elastic outer layer. After locking the lesion coordinates through the X-ray image, the doctor can directly use the physical mark holes to accurately mark on the skin of the patient, realizes 1:1 lossless conversion of the image coordinates to the body surface mark, greatly improves the accuracy of the hand tumor surgery and reduces the surgical damage.

The application belongs to the technical field of fluorescent probe, and particularly relates to an aminopeptidase fluorescent probe and a preparation method and application thereof. In order to develop an APN near-infrared fluorescent probe suitable for in vivo imaging, a center-position ester group substituted pentamethine cyanine dye platform (Cy5-COOM) is used, and based on an "ester group to carboxyl group" conversion strategy, an aminopeptidase (APN) fluorescent probe Cy5-APN is developed. The probe is firstly hydrolyzed by APN, then a 1,6-elimination reaction occurs, and finally a strong fluorescent center-position carboxyl group substituted pentamethine cyanine dye Cy5-COO is released. In addition, in view of the characteristics that cancer cell surfaces overexpress APN, the probe can distinguish cancer cells / tissues and normal cells / tissues with high contrast, and therefore has great application potential in fluorescence-guided tumor surgery.

This utility model discloses a bipolar radiofrequency electrode for bone tumor surgery, which includes a cable assembly, a handle, a scalpel, and a scalpel head connected in sequence. The scalpel head includes a suction tube and an outer steel tube that is spaced and sleeved on the suction tube, with a water outlet channel formed between the suction tube and the outer steel tube. The scalpel head includes an insulating head fixed to the distal end of the outer steel tube. The insulating head is provided with a first strip electrode and a second strip electrode arranged side by side. The insulating head located at the first strip electrode and the second strip electrode has several suction holes, which are connected to the suction tube. Several water outlet holes connected to the water outlet channel are provided on both sides of the distal end of the outer steel tube. This solution uses radiofrequency electrodes to irrigate the incision after the resection of benign spinal tumors, which can accurately stop bleeding at soft tissue bleeding points, effectively reducing the amount of bleeding. Furthermore, by utilizing the circulating supply of physiological saline, the first strip electrode and the second strip electrode are effectively wrapped by physiological saline, thereby ensuring the plasma excitation efficiency.

The invention discloses an auxiliary walking frame used after gynecological tumor operation, and belongs to the technical field of medical auxiliary instruments. The walking frame comprises a main support, wheel portion supports are symmetrically and fixedly installed at the lower end of the main support, and walking wheels are rotationally installed at the front ends and the rear ends of the wheel portion supports; a multifunctional chair piece which can be folded and spliced is arranged on the outer side of the main support, and the multifunctional chair piece can be adjusted to switch a back supporting and protecting mode and a seat mode; the main support is further provided with a gravity center monitoring assembly, the wheel support is rotationally provided with a lateral anti-inclination assembly used for auxiliary supporting, and the lateral anti-inclination assembly is driven and adjusted through the gravity center monitoring assembly. According to the walking assisting frame, a drainage bag and an infusion bag can be conveniently hung, the supporting and temporary sitting and leaning functions can be provided for a patient by adjusting the folding chair plate, meanwhile, the auxiliary supporting and body supporting functions can be automatically started when lateral inclination occurs, the toppling accident is effectively prevented, and the use safety is high.

The invention relates to the technical field of health-care food, in particular to a polysaccharide and fungus extract synergistic protein nutrient enrichment composition for postoperative recovery of tumor patients and a preparation method of the polysaccharide and fungus extract synergistic protein nutrient enrichment composition. The invention relates to a polysaccharide and fungus extract synergistic protein nutrition fortification composition for postoperative and tumor patient recovery. Comprising the following components in percentage by weight: 20-27% of coconut oil powder, 35-45% of protein powder, 16-24% of a prebiotic dietary composition, 4-8% of carbohydrates, 2-3% of compound minerals, 0.01-0.2% of fish oil powder, 3.5-6% of an immunity composition, 0.2-1.5% of vegetable powder, 0.01-0.08% of concentrated milk flavor powder essence and the balance of compound vitamins. The composition prepared by the invention is applied to postoperative tumor patients, can enhance the immunity of the postoperative tumor patients, can also reduce inflammatory factors in serum, is suitable for the postoperative tumor patients to take, is relatively good in taste, easy to accept by the patients, scientific in proportion, convenient to take, free of toxic and side effects and capable of being eaten for a long time.

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a gynecological tumor operation picking device which comprises a connecting plate, a handle is fixedly connected to one end of the connecting plate, a sliding block is slidably connected to one side of the connecting plate, a displacement plate is fixedly connected to one side of the sliding block, clamping rods are slidably connected to the two sides of the displacement plate, and the clamping rods are slidably connected to the two sides of the displacement plate. The end part of the clamping rod is fixedly connected with a picking block; the device further comprises a picking and storing assembly. According to the tumor picking and storing device, by means of the picking and storing assembly, every time one tumor is picked, the tumor can be placed in the storing barrel, each tumor has an independent placing area, and the situation that the placed tumor falls out until all the tumors are picked due to the fact that the next tumor is placed is avoided. In the whole process, the picking block does not need to go in and out of the body of a patient repeatedly, so that the operation time is remarkably shortened, meanwhile, additional trauma caused by frequent friction of incision tissue is avoided, and the pain degree of the patient after an operation is relieved.

This invention belongs to the field of nanomedicine technology, specifically relating to a pH / hypoxia dual-responsive polymer, nanomicelles, their preparation method, and applications. The pH / hypoxia dual-responsive polymer is a hydroxyethyl deacetylated chitosan modified with p-nitrobenzyl chloroformate and cinnamaldehyde. Ropivacaine is loaded onto it and prepared into nanomicelles for use as a drug delivery system after tumor surgery. Due to its acid sensitivity and hypoxia response, it can intelligently identify the tumor microenvironment, achieving precise drug delivery.

The invention relates to the technical field of tissue specimen preservation, in particular to tumor specimen auxiliary storage equipment for tumor surgery. The device comprises a base, the top of the base is rotationally connected with an adjusting sealing cover, a low-temperature cavity is defined by the interior of the adjusting sealing cover and the top of the base, and the top of the adjusting sealing cover communicates with an air inlet; when the tumor specimen in the low-temperature cavity is taken out, the top of the side, away from the axis, of the specimen temporary storage piece is in sliding fit with the inner bottom wall of the sealing block, it is ensured that the space size of the buffer cavity is gradually reduced, and it is ensured that the upper portion of the buffer cavity is always kept sealed, so that a positive pressure space is formed in the buffer cavity; cold air originally coming from the low-temperature cavity in the inner part is discharged from an opening which is opened due to the rising of the sealing block; when a new clinical tumor specimen is stored in the low-temperature cavity, external air in a buffer cavity space below the low-temperature cavity is driven away through the downwards-pressed sealing block.

The invention relates to the technical field of gynecological tumor, and provides tumor stripping equipment for gynecological tumor surgery, which comprises a rod body, a stripping end for mounting a stripping assembly and a control end for mounting a control assembly are respectively arranged at two ends of the rod body, and the control end and the stripping end are connected through a connecting straight rod. A handle is further fixedly connected to one side of the control end, a guide assembly used for guiding a pull rope is arranged between the stripping assembly and the control assembly, through arrangement of a damper, a centering guide wheel and other structures, the damper and a spring act synergistically, the impact force generated when the clamping jaw is opened and closed is effectively absorbed, tissue damage is prevented, and the service life of the clamping jaw is prolonged. And the centering guide wheel groups which are uniformly distributed on the circumference ensure that the pull rope is always conveyed along a central path through rolling support, so that transmission deviation and clamping stagnation are avoided, the stability and the safety of equipment operation are obviously improved, and the problems of instability and insufficient precision in the prior art are solved.

The invention relates to the field of biomedical materials, in particular to a biodegradable medical magnesium-copper-germanium alloy and a preparation method and application thereof, and the biodegradable medical magnesium-copper-germanium alloy is particularly suitable for implantation and intervention products in the tumor surgery department and can play multiple biological functions such as antibiosis and anti-tumor functions. The copper alloy comprises the following components in percentage by weight: 0.1-0.3% of Cu, 0.5-1.5% of Ge and inevitable impurity element lt, 0.01%, and the balance of Mg. The germanium element with an excellent anti-tumor effect is added into the magnesium alloy, the germanium content is 1.5% or below, the biodegradable medical magnesium-copper-germanium alloy is prepared through vacuum purification smelting, meanwhile, the existence form of the germanium element in the magnesium alloy is changed, the microstructure of the magnesium alloy is regulated and controlled, and then the degradation speed of the germanium-containing magnesium alloy is controlled; the anti-tumor effect is achieved by changing the tumor tissue microenvironment, promoting tumor inhibition protein expression and the like.

A method for preparing a bionic injectable polypeptide hydrogel is provided. The hydrogel is formed using a brain extracellular matrix laminin-derived peptide DDIKVAV modified with 9-fluorenylmethoxycarbonyl (Fmoc) (Fmoc-DDIKVAV) and an immunostimulatory peptide FTKPRF modified with Fmoc (Fmoc-FTKPRF) as hydrogel monomers. These monomers further utilize non-covalent bond forces such as hydrogen bonds, hydrophobic interactions, and x-x stacking to co-assemble into a hydrogel within a short time at 37° C. The bionic hybrid polypeptide hydrogel is injectable and can serve as a drug reservoir implanted into cavities formed after tumor surgery. The drugs loaded in the hydrogel are slowly released at a stable and controlled rate and appropriate concentration within the post-surgical cavity, thereby effectively killing residual tumor cells while avoiding the toxic side effects of systemic drug administration.

The invention belongs to the technical field of bone repair materials, and discloses a preparation method of a cross-scale gradient structure, a bone repair material and an application method. The preparation method comprises the following steps: preparing a semiconductor biological material into a biological heterojunction suspension, and mixing the biological heterojunction suspension with photocuring hydrogel to form a system; a bone implant base material and a conductive material are respectively used as a positive electrode and a negative electrode to be placed in a system, an electric field is applied to enable the biological heterojunction particles to directionally deposit to form a gradient, the bone repair material with a cross-scale gradient structure is obtained through photo-curing fixation, and a porous scaffold can be preset as required. The material prepared by the method simulates a natural gradient structure of a human skeleton, has composite functions of electric conduction, antibiosis and the like, can give consideration to mechanical support and biological activity, is adaptive to scenes of spine repair, tumor postoperative bone defects and the like, solves the problems that a traditional bone repair material is not matched in structure and single in function, and improves osseointegration efficiency and clinical safety.

This invention provides a wound healing dressing for postoperative care of tumor patients and its preparation method, belonging to the field of postoperative dressing technology. The dressing comprises boric acid-grafted GelMA, caffeoyl tartaric acid-grafted CSMA, aldehyde-modified diallyl tartaramide, sodium alginate, catechins, ferric chloride, and calcium chloride. Its preparation process utilizes dynamic imine bonds, UV-induced covalent cross-linking, ionic cross-linking, and metal coordination to construct a multi-layered cross-linked interpenetrating network structure. The resulting dressing possesses both high strength and good toughness, allowing it to closely adhere to irregular wound surfaces. The rapid initial release of catechins provides immediate antioxidant and hemostatic effects, while catechols are continuously and slowly released under the influence of the microenvironment. Simultaneously, cationic chitosan, catechins, and iron ions synergistically provide antibacterial effects, and calcium alginate promotes coagulation, while GelMA promotes cell adhesion and proliferation, comprehensively promoting wound healing, reducing the risk of infection, and making it suitable for the care of complex wounds after tumor surgery.

The application discloses a composite nano-silicon ball drug delivery system and a preparation method and application thereof. The system takes mesoporous silica nanoparticles as a carrier, loads gefitinib, and is coated with a PD-L1 antibody modified platelet membrane on the surface. The application prepares a composite multifunctional mesoporous silica nanoparticle which loads gefitinib and is coated with a PD-L1 antibody modified platelet membrane on the surface, so that the composite multifunctional mesoporous silica nanoparticle can be directed to reach a tumor surgery blood vessel damage site, kill residual tumor cells, reduce matrix hardness in the microenvironment, enhance the permeability and toxicity of immune cells, the two effects are interdependent and mutually enhanced, and the application overcomes the invalidity of colorectal tumor immunotherapy and prolongs the survival period of patients.

The invention relates to a DLL4-VEGF (vascular endothelial growth factor) dual-targeting aggregation-induced emission nanoprobe, a preparation method thereof and application of the DLL4-VEGF dual-targeting aggregation-induced emission nanoprobe in tumor surgical navigation, the DLL4-VEGF dual-targeting aggregation-induced emission nanoprobe comprises a VEGF target targeting peptide, a self-assembly polypeptide and a DLL4 target targeting peptide which are connected in sequence, and fluorescence imaging molecules are connected to the VEGF target targeting peptide. The probe can effectively permeate into a deep tumor area due to the small-size characteristic, so that high permeability is realized; meanwhile, DLL4 and VEGF overexpressed on the surfaces of cancer cells can be specifically combined, tumor boundaries and tiny metastases are accurately recognized, and the enrichment capacity of tumors at target sites is remarkably enhanced; meanwhile, the probe carries a fluorophore and is suitable for real-time fluorescence navigation of laparoscope / robot-assisted tumor resection; the probe exists in the form of nanoparticles in body fluid circulation, forms change and gather to form nanofibers when reaching a tumor microenvironment, and can realize long-acting retention of a target part, so that high-resolution fluorescence imaging and precise surgical navigation are realized.

The utility model relates to the technical field of tumor surgery, in particular to a pediatric clinical treatment catheter limiting device. The utility model provides a pediatric clinical treatment catheter limiting device capable of improving the comfort level of a patient. The pediatric clinical treatment catheter limiting device comprises a soft mounting plate, an elastic band, a silica gel strip, a first sliding block, a rubber guide ring, a fixing frame, a rotating shaft, a first sliding guide wheel, a second sliding block, a second sliding guide wheel and the like. An elastic band is connected to the soft body mounting plate, a first sliding block is slidably connected to the soft body mounting plate, a rubber guide ring is fixedly connected to the first sliding block, two fixing frames are connected to the bottom of the soft body mounting plate, and a rotating shaft is rotatably connected between the two fixing frames. The guide tube is limited through the first sliding guide wheel and the second sliding guide wheel, the guide tube is prevented from deviating, medical staff can be reminded that the guide tube moves too fast through the cam, the contact rod, the alarm and other components, the skin and organs of a child are prevented from being damaged when the guide tube is inserted into the child, and the comfort of a patient is improved.

The present invention relates to a method and reagents for detecting DNA methylation. Specifically, the present invention relates to a method for diagnosing the presence or absence of a tumor in a subject, a method for diagnosing the presence of microresidual lesions after tumor surgery, a method for determining the postoperative prognosis of a subject with a tumor, a method for predicting postoperative recurrence in a subject with a tumor, or a method for evaluating the therapeutic effect on a subject with a tumor, by detecting a methylation marker in free DNA in a sample derived from the subject and determining the methylation level of the DNA. The present invention also relates to a marker, a kit, and a detection reagent used in the above method.

This application discloses a method, system, and device for in-situ 3D reconstruction of tumor surgical boundaries and intraoperative navigation, relating to the medical field. The method includes: obtaining a set of two-dimensional pixel coordinates of key points of the tumor tissue detection probe based on image frame data using a constructed key point detection model; calculating the 3D coordinates of the probe detection focus in the camera coordinate system using a determined rigid body transformation matrix and pre-calibrated probe detection focus model coordinates; generating a point cloud with cancerous / non-cancerous pathological attributes based on timestamps, spectral data, and 3D coordinates; connecting the point cloud with cancerous pathological attributes in chronological order to form a continuous spatial contour line; and dynamically overlaying this contour line onto the current image frame based on camera intrinsic parameters to achieve intraoperative navigation. This application overcomes the limitations of current methods, such as being limited to single-point detection and unable to construct continuous spatial geometric information, as well as the pain point of the detection probe's tip being easily occluded during continuous movement close to the affected area, leading to positioning loss.

This invention relates to the field of surgical navigation technology for tumor treatment, specifically to an intelligent navigation system for nasal skull base tumor surgery based on multimodal image fusion. The system includes an image acquisition module for acquiring and rigidly registering CT and MRI images to determine the initial tumor region; a tumor invasion degree acquisition module for quantifying the local tumor invasion degree by combining CT grayscale distribution characteristics and MRI apparent diffusion coefficient characteristics; an invasion path acquisition module for simulating a fully covered digital invasion path based on anisotropic diffusion of image features; a risk infiltration degree acquisition module for comprehensively considering distance, direction, and invasive activity to assess the risk of invasion path infiltrating key structures; and a tumor boundary acquisition module for obtaining the tumor biological boundary by correcting the anatomical boundary through risk infiltration degree. This invention effectively improves the accuracy and safety of nasal skull base tumor surgery by acquiring the tumor biological boundary.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a medicated pack for local edema after tumor surgery and radiotherapy, and its preparation method. The medicated pack comprises the following raw materials in parts by weight: Astragalus membranaceus 20-30 parts, Paeonia lactiflora 20-30 parts, Glauber's salt 20-30 parts, Poria cocos 15-20 parts, Curcuma longa 15-20 parts, Borneol 10-15 parts, Typha pollen 10-15 parts, self-heating matrix 20-40 parts, hyaluronic acid 30-70 parts, and glycerin 50-80 parts. The traditional Chinese medicines used have the effects of promoting diuresis and reducing swelling, promoting blood circulation and removing blood stasis, and anti-inflammatory and analgesic properties. The prepared self-heating matrix has the characteristics of continuous and controllable hygroscopic and heat-releasing properties, which can promote the formation of a gel state in the medicated pack during use, providing a warm environment for the transdermal transdermal absorption of the active ingredients of the traditional Chinese medicine, effectively improving the symptoms of local edema after tumor surgery and radiotherapy, and has high clinical application value.

The utility model relates to the technical field of hemostasis equipment, and discloses a hemostasis device for a clinical operation in the oncology surgery department, which comprises two plastic plates, rubber bodies are respectively arranged below the two plastic plates, a medicine pad is arranged between the two rubber bodies, the upper end of one plastic plate is fixedly connected with a connecting block, and the lower end of the other plastic plate is fixedly connected with a connecting rod. One side of the connecting block is fixedly connected with soft cloth, the lower end of the soft cloth is fixedly connected with a son hook-and-loop fastener, the lower end of the son hook-and-loop fastener is bonded with a mother hook-and-loop fastener, the mother hook-and-loop fastener is fixedly connected with the other plastic plate, the two plastic plates are bonded to the two sides of the wound through the colloid, and the medicine pad makes contact with the wound. The device is used for fixing the two plastic plates, so that the hemostasis effect is achieved, then the soft cloth is pulled, the two plastic plates are positioned under the cooperation of the son hook-and-loop fastener and the mother hook-and-loop fastener, then the wound is prevented from being broken open, and the device is a disposable product, so that the hemostasis effect is effectively achieved, and secondary pollution to the affected part of a patient is prevented.

The invention provides a method for generating a three-dimensional CT (computed tomography) image from a cross-modal dual-view DR (digital radiography) image based on structure guidance, which comprises the following steps of: constructing a dual-branch encoder network guided by structure prior, respectively extracting dual-view image features, and fusing direction difference perception information to enhance three-dimensional structure perception; cT volume data are generated step by step through a layer-by-layer voxel growth reconstruction module, and the fuzzy problem caused by traditional overall regression is avoided; a global-local collaborative attention mechanism is introduced to strengthen detail expression of a key anatomical region, and a multi-objective loss function driven by structural consistency is designed, so that the clinical availability and anatomical precision of a synthesized image are effectively improved. The method has the advantages that the three-dimensional CT image consistent in structure and reliable in density can be accurately synthesized through the double-angle DR image on the premise that additional three-dimensional scanning is not needed. The method can be widely applied to surgical planning of orthopedics, tumors and the like, dependence on traditional three-dimensional images is remarkably reduced, and reliable image support is provided for surgical navigation.

The utility model relates to the technical field of medical instruments, in particular to a gastrointestinal tumor surgery diversion device. The gastrointestinal tumor surgery diversion device comprises a diversion bottle, a thickening layer is arranged at the bottom of the diversion bottle, and a plurality of clamping grooves distributed in the circumferential direction are formed in the thickening layer; a rotating shaft is fixed on the thickening layer, and a limiting rotating disc is rotationally connected to the rotating shaft; a thickening layer is additionally arranged at the bottom of an original flow guide bottle, and a supporting mechanism, a supporting ring, a sleeving piece, anti-skid lines, a hand screwing bolt, a connecting strip, a limiting rotating disc, a rotating shaft, a limiting groove, an embedding opening, an elastic clamping head, a positioning groove and a clamping groove are arranged, so that the sleeving piece can be fixed to an infusion support, and therefore the flow guide bottle is placed in a suspended mode; and moreover, the flow guide bottle is fixed on the infusion support, so that medical staff can conveniently observe the internal liquid amount, diagnosis and treatment of the patient are facilitated, and the infusion support is high in practicability.

The application discloses a nerve tumor surgery postoperative rehabilitation nursing device, and relates to the technical field of nerve tumor surgery, which comprises a nursing helmet, and an air bag neck ring is arranged at the bottom of the nursing helmet. The nerve tumor surgery postoperative rehabilitation nursing device can continuously cool the top of the head of a patient, so that the wound site is kept in a dry state at all times, a good nursing and healing environment is provided for the rapid recovery of the wound site, the head of the patient is helped to dissipate heat in a large area, the feeling of stuffiness and discomfort of the head caused by long-time wearing of the nursing helmet is eliminated, the wound site is prevented from being excessively pressed, a child lock mode is provided, direct scratching of the wound site by the hands of children is effectively prevented, the normal recovery of the wound site is protected, wound healing is accelerated, scarring is prevented, automatic diffusion type medicine application wet nursing effect on the wound site of the head of the patient is realized, and slow medicine application on the wound site is realized.

The utility model relates to the technical field of medical instruments, and provides a radioablation device for tumor surgery, which comprises a device main body, a servo motor I is fixedly connected to the top of an inner cavity of the device main body, a support plate I is fixedly connected inside the device main body, the servo motor I is fixedly connected with a reciprocating screw rod I through an output shaft, and the reciprocating screw rod I is fixedly connected with a support plate II through an output shaft. A first reciprocating lead screw is fixedly connected to the upper portion of the base, a first bearing seat is arranged outside the first reciprocating lead screw, the first reciprocating lead screw and the first bearing seat are connected through a ball nut pair, a movable table is fixedly connected to one side of the outer portion of the first bearing seat, a second servo motor is fixedly connected to one side of the inner cavity wall of the movable table, and a second supporting plate is fixedly connected to the interior of the movable table. By means of the technical scheme, the problems that in the prior art, the position and height of a traditional tumor ablation device are generally manually adjusted, the precision of the manually adjusted device can be reduced, and therefore the effect after ablation treatment is poor, and the expected effect cannot be achieved are solved.

The invention discloses a composition based on a paclitaxel derivative as well as a preparation method and application of the composition, and belongs to the technical field of biological medicines. The composition is formed by dynamically assembling phenylboronic acid modified paclitaxel and saccharides through boric acid ester bonds, and the dosage form of the composition comprises gel, injection or freeze-dried powder. According to the composition, the dissolving property of the paclitaxel is remarkably improved, the solubility of the paclitaxel reaches the milligram level for direct intravenous injection, and the composition does not need to depend on a solubilizer. In addition, based on the dynamic assembly characteristic, micromolecule self-assembly gel can be constructed and is suitable for tumor postoperative local treatment. The invention provides a new thought for development of an indissolvable drug delivery system, and provides a safe and effective drug delivery strategy for tumor treatment.