Health-care product for preventing and treating premature ovarian failure and preparation method thereof

A technology for premature ovarian insufficiency and health care products, which is applied in food preparation, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve the effects of promoting follicle development, good ovarian function, and regulating responsiveness

Inactive Publication Date: 2011-02-02
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the method of preventing and treating premature ovarian failure by combining medicine and food.

Method used

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  • Health-care product for preventing and treating premature ovarian failure and preparation method thereof
  • Health-care product for preventing and treating premature ovarian failure and preparation method thereof
  • Health-care product for preventing and treating premature ovarian failure and preparation method thereof

Examples

Experimental program
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Effect test

experiment example

[0026] Experimental Materials:

[0027] Galactose feed: D-galactose was mixed into common rat feed at a concentration of 35%.

[0028] Experimental animals: 72 healthy female SD rats, aged 8 to 12 weeks, weighing 200 to 250 g, raised at a temperature of 23 to 25°C, with a relative humidity of 50 to 60%, free access to water and food, and 12 hours of light per day. Adaptive feeding.

[0029] experimental method:

[0030] After one week of adaptive feeding, 72 rats were randomly divided into 6 groups, 12 in each group, respectively blank control group, model group, oral liquid group, granule group, ointment group, and pill group. Rats in the model group were fed with 35% D-galactose feed for modeling, and rats in other groups were fed with normal rat feed. The rats in the blank control group and the model group were gavaged with purified water once a day, the rats in the oral liquid group were gavaged with oral liquid once a day, and the rats in the granule group, ointment gr...

Embodiment 1

[0051] Embodiment 1: the oral liquid preparation of health product of the present invention

[0052] Lycium barbarum 100g, Ligustrum lucidum 100g, Rehmannia glutinosa 100g, Epimedium 150g, Psoralen 100g, Cuscuta 100g, soak in 10 times the amount of 60% ethanol for 8 hours, then reflux extraction for 2.5 hours, filter, the filtrate is set aside, and the filter residue continues Reflux extraction twice, reflux extraction with 8 times the amount of 60% ethanol for 1.5 hours each time, filter, and use the filtrate for later use, combine the above filtrates, and concentrate until there is no alcohol smell to obtain an alcohol extract. The filter residue is decocted twice with water, the first time is decocted with 10 times the amount for 2 hours, the second time is decocted with 8 times the amount for 1 hour, and filtered to obtain the water extract. Combine the alcohol extract and the water extract, put it in a configuration tank, add simple syrup, honey, sodium benzoate, and dist...

Embodiment 2

[0053] Embodiment 2: the oral liquid preparation of health care product of the present invention

[0054] 100g medlar, 100g privet fruit, 100g rehmannia glutinosa, 150g epimedium, 100g psoralen, 100g raspberry, 100g dodder, 200g peanut, 200g red date, 200g soybean, soak in 10 times the amount of 60% ethanol for 8 hours, Then reflux extraction for 2.5 hours, filter, and the filtrate is set aside, and the filter residue is refluxed and extracted twice, each time with 8 times the amount of 60% ethanol for reflux extraction for 1.5 hours, filtered, and the filtrate is set aside, the above filtrates are combined, and concentrated until no alcohol smell, to obtain alcohol Extraction. The filter residue is decocted twice with water, the first time is decocted with 10 times the amount for 2 hours, the second time is decocted with 8 times the amount for 1 hour, and filtered to obtain the water extract. Combine the alcohol extract and the water extract, put it in a configuration tank, ...

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Abstract

The invention discloses a health-care product for preventing and treating premature ovarian failure and a preparation method thereof. The health-care product comprises medlar, glossy privet fruit, prepared rehmannia, epimedium, malaytea scurfpea fruit, Chinese dodder seeds, raspberry, peanut, Chinese date and soy. The preparation method comprises the following steps of: weighing raw materials according to a weight proportion; soaking with ethanol; performing reflux extraction; filtering, and keeping the filtrate for later use; performing reflux extraction on the residue twice with ethanol; re-filtering, and keeping the filtrate for later use; combining the filtrate, and concentrating the filtrate until ethanol odor does not exist so as to obtain ethanol extract; and decocting the residue twice, filtering to obtain water extract, and combining the ethanol extract and the water extract to obtain the health-care product. The health-care product has excellent effect of improving the ovary function, and has the effects of improving the ovary function, achieving the effect of estrogen, improving the symptoms of weight loss, desudation and the like caused by ovarian failure, regulating the response of the ovary to gonadotropin, promoting follicular development and the like for 40-year-old women particularly.

Description

technical field [0001] The invention relates to a health food and a preparation method thereof, in particular to a health product for preventing and treating premature ovarian failure and a preparation method thereof. Background technique [0002] Premature ovarian failure (POF) refers to women who have established regular menstruation. Before the age of 40, persistent amenorrhea and sexual organ atrophy occur due to ovarian function decline. There is often an increase in gonadotropin levels and a decrease in estrogen. Symptoms related to menopausal syndrome: varying degrees of hot flashes, hyperhidrosis, dizziness, mood swings, insomnia and decreased libido, and other clinical manifestations of low ovarian function. [0003] Western medicine believes that the related etiology of POF is complex, its pathogenesis is still unclear, and its treatment is also quite difficult. Currently recognized etiologies include genetic factors, immune factors, iatrogenic factors, environmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61P15/00A61K9/16A61K9/06A61K36/815A61K9/20A23L1/29A23L33/00
Inventor 王旭东葛盛沈健晏婷婷
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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