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63 results about "Genetic profile" patented technology
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Genetic profiling - the procedure of analyzing the DNA in samples of a person's body tissue or body fluid for the purpose of identification.
Transcriptome microarray technology and methods of using the same
InactiveUS20060134663A1Stable designFacilitates cross-validation studiesBioreactor/fermenter combinationsBiological substance pretreatmentsTissue sampleDiagnoses diseases
Arrays containing a transcriptome of a diseased tissue and methods of using the arrays for diagnosis, prognosis, screening, and identification of disease are provided herein. The transcriptome arrays from diseased tissue are useful for diagnosis of a disease by analysis of the genetic profile of a tissue sample specific to a disease state. The genetic profiles are then correlated with data on the effectiveness of specific therapeutic agents. Correlating expression profiles to the effectiveness of therapeutic agents provides a way to screen and select further patients predicted to respond to those therapeutic agents, thereby minimizing needless exposure to ineffective therapy.
Owner:ALMAC DIAGNOSTICS LIMITED
Sample Preparation, Processing and Analysis Systems
ActiveUS20130115607A1Small footprintFast timeBioreactor/fermenter combinationsBiological substance pretreatmentsGenetic profileBioinformatics
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.
Owner:INTEGENX
Sample preparation, processing and analysis systems
ActiveUS20150024436A1Small footprintFast timeSludge treatmentVolume/mass flow measurementAnalyteAllele
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.
Owner:INTEGENX
Cancer profiles
InactiveUS20030165954A1Great advantageMicrobiological testing/measurementRecombinant DNA-technologyCancer typeOncology
The present invention relates to genetic profiles and markers of cancers and provides systems and methods for screening drugs that are effective for specific patients and types of cancers. In particular, the present invention provides personalized treatment customized to an individual's cancer.
Owner:THIRD WAVE TECH
Sample preparation, processing and analysis systems
ActiveUS8894946B2Small footprintFast timeBioreactor/fermenter combinationsHeating or cooling apparatusAnalyteAllele
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.
Owner:INTEGENX
Sample preparation, processing and analysis systems
InactiveUS20150136604A1Small footprintFast timeElectrolysis componentsVolume/mass flow measurementAnalyteAllele
This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.
Owner:INTEGENX
System, method and DEVICE for making AND DELIVERING Genetic-based personalized NUTRIENT AND SUPPLEMENT MIXTURES
InactiveUS20070073557A1Reduce deliveryNutrition controlPayment architecturePersonalizationUser input
A system for preparing a genetically-based personalized mixture of nutrients and other ingredients that includes an input device to input genetic information of a user into the system, an identifying device to identify a genetic profile of the user based on the user input information, and a processing device to process the information inputted by the user and identify a mix and concentration of ingredients stored in the system to be prepared based on the genetic profile of the user. The system also includes a mixing device to mix a customized beverage to deliver to the user where the customized beverage includes the mix and concentration of ingredients prepared based on the genetic profile of the user.
Owner:ALPHAGENICS
Transcriptome microarray technology and methods of using the same
InactiveUS20090221437A1Stable designFacilitates cross-validation studiesMicrobiological testing/measurementLibrary screeningTissue sampleDisease status
Owner:ALMAC DIAGNOSTICS LIMITED
Class I and Class II MHC Profiling for Social and Sexual Matching of Human Partners
An improved process of matching people with one another, for social and / or sexual purposes, based on the profiles of the participants' Class I and Class II MHC genes. The quality of this human matching is inversely proportional to the number of common alleles of said genetic profiles of the individuals. Higher quality matches of this type result in greater sexual attraction, more attractive physical odor, and offspring with more robust immune systems among matched participants.
Owner:HOLZLE ERIC
Method for preparing and using personal and genetic profiles
Method and system for preparing a personal genetic profile includes collecting genetic data from an individual, assigning the data to a coordinate system, storing the data, and providing access for retrieval by the individual from whom the genetic data were collected, after receipt of an Identifier that adequately authenticates the identity of the data requestor. Locations of genetic markers are provided as three-dimensional coordinates, described with matrix relationships that are consistent with the primary and secondary chemical structure of molecular constituents of a DNA chain for the individual.
Owner:RATHJEN ALICEMARIE G +9
Medical literature database search tool
InactiveUS20050086078A1Data processing applicationsMedical equipmentDisease classificationLibrary science
In some embodiments, disease classification system identifiers are received; disease classification system identifiers are translated into medical literature classification system identifiers; a medical literature database is filtered based on relevance to evidence-based medicine; and medical literature articles are identified from a medical literature database based on medical literature classification system identifiers. Various embodiments add, delete, and modify portions of the claimed methods and apparatuses. In other embodiments, genetic profiles of patients are received; genetic profiles are translated into medical literature classification system identifiers; a medical literature database is filtered based on relevance to evidence-based medicine; and medical literature articles are identified from a medical literature database based on medical literature classification system identifiers. Various embodiments add, delete, and modify portions of the claimed methods and apparatuses. Some embodiments include code on a computer readable medium.
Owner:COGENT MEDICINE
Social genetics network for providing personal and business services
InactiveUS20140108527A1Data processing applicationsMultiple digital computer combinationsGenetic networkGenetic data
Creation of a social genetics network that provides personal and business services includes: receiving non-genetic data and genetic data about a user and storing the non-genetic data and genetic data in a database; analyzing the genetic data and the non-genetic data to i) assign traits to the user based at least in part on phenotypic and / or genotypic relationships found in the genetic data and the non-genetic data, and ii) determine trait connections between the user and other users in the network based on a similarity of the traits that are common to the user and the other users; and generating and displaying on an electronic device a social genetics profile that includes at least a portion of the non-genetic data, at least a portion of the traits assigned to the user, and at least a portion of the trait connections of the user to the other users.
Owner:FABRIC MEDIA
METHOD FOR DETECTING IGF1R/Chr 15 in CIRCULATING TUMOR CELLS USING FISH
InactiveUS20090258365A1Microbiological testing/measurementBiological material analysisFluorescenceCirculating cancer cell
The present invention describes methods and probe composition for an automated FISH assay of a blood sample containing circulating tumor cells expressing the IGF-1R gene. The assay provides genetic analysis of suspect circulating tumor cells that have been identified after immunomagnetic selection and fluorescent labeling. Using unique, repeat-free probes to the IGF-1R locus and a chromosome 15 reference probe, cell lines expressing an aberrant number of IGF-1R and Chr 15 signals were detected, including one cell line with a low level of IGF-1R amplification. The ability to directly examine the genetic profile of IGF-1R on circulating tumor cells may provide an automated means for assessing disease and patient response to therapy.
Owner:VERIDEX LCC
Individualized, genetically-determined dietary supplementation and exercise recommendation with container and dispenser for same
A method, system, and device for providing nutritional detailed dietary (menu planning), exercise, and life coaching guidance and nutritional supplements to maximize Wellness (health and fitness) to a person based on a portion of the person's genetic SNP profile, taking account of at least about 30 genes and variations therein. The person provides a tissue sample to a genetic analysis laboratory, which issues its SNP report. That report, together with the person's responses to a personal habits questionnaire, is analyzed by a nutritionist and also an exercise therapist and a monthly dietary supplementation plan and recommended lifestyle changes are provided to the person. A supplements box is provided to the person with daily and intra-daily doses of prescriptions and supplements, the box containing at least 4 weeks' worth of supplements. The box is filled and refilled monthly to the specifications of the nutritionist, exercise therapist, and lifestyle coach to assist the person in achieving optimum health and vitality, i.e., wellness.
Owner:HUGHES TIMOTHY P
Genetic profile imaging and data-sharing device and methodology for socially relevant traits
The present invention generally relates to genetic profiling and genetic data-sharing and, more particularly, is concerned with a system and method for genetic profile imaging and for determining and sharing information about a person's socially relevant traits. The present invention provides a means by which a person can safely share information about his or her genetic makeup, where the information is related to normal functions and unrelated to disease or illness.
Owner:ALPHAGENICS
Genome-Wide Association Study Identifying Determinants Of Facial Characteristics For Facial Image Generation
InactiveUS20130039548A1Promote generationBiometric pattern for forensic purposeImage enhancementA-DNAOrganism
The present invention relates to a method for the generation of a facial composite from the genetic profile of a DNA-donor. The method comprises the steps of a) subjecting a biological sample to genotyping thereby generating a profile of genetic markers associated to numerical facial descriptors (NFD) for said sample, b) reverse engineer a NFD from the profile of the associated genetic variants and constructing a facial composite from the reverse engineered numerical facial descriptors (NFDs). The present invention also relates to a method for identifying genetic markers and / or combinations of genetic markers that are predictive of the facial characteristics, (predictive facial markers) of a person, said method comprising the steps of: a) capturing images of a group of individual faces; b) performing image analysis on facial images of said group of individual faces thereby extracting phenotypical descriptors of the faces; c) obtaining data on genetic variation from said group of individual and d) performing a genome-wide association study (GWAS) to identify said predictive facial markers.
Owner:DANMARKS TEKNISKE UNIV
System for Tracking and Optimizing Health Indices
ActiveUS20150100350A1Data processing applicationsHealth-index calculationHealth indexComputer science
A system and method for tracking and optimizing health indices is provided. In some embodiments the system provides for tracking and / or optimizing health indices of one or more individuals having a particular genetic profile and adaptively managing external factors the individual experiences so as to optimize a change in one or more health indices based on the individual's genetic profile.
Owner:MINVIELLE EUGENIO
Use of Mass Labelled Probes to Detect Target Nucleic Acids Using Mass Spectrometry
InactiveUS20070292861A1Sugar derivativesMicrobiological testing/measurementBiological bodyMass Spectrometry-Mass Spectrometry
The invention relates to the use of mass labelled probes to characterise nucleic acids by mass spectrometry. Thus the invention provides methods of detecting the presence of a target nucleic acid in a sample, using a circularising probe in which a mass tag is present in the probe. Further methods of detecting the presence of a target nucleic acid are provided, which in contrast use a probe detection sequence in the circularising probe, wherein the probe detection sequence is detected with a probe attached to a mass tag. Methods for determining a genetic profile from the genome of an organism also form part of the invention.
Owner:TRILLION GENOMICS
Method And System For Comprehensive Knowledge-Based Anonymous Testing And Reporting, And Providing Selective Access To Test Results And Report
InactiveUS20080195326A1Prevent and delay and decrease chanceStimulate physical activityBioreactor/fermenter combinationsBiological substance pretreatmentsThird partyAnonymous Testing
A method and system (100) for comprehensive knowledge-based genetic and other testing and for providing selective access to testing results (120) thereof. In particular, a method and system is provided for the personal, anonymous and confidential examination of the genetic profile of any gene or combination of genes and examining any mutations of such genes to assess the risk of developing a condition, such as a medical disease, or to identify personal characteristics and / or traits. Other data, such as chemical analysis, environmental, personal and family history of medical, behavioral, and other factors can be incorporated to generate a comprehensive knowledge-based assessment. The method and system also include features for providing secure confidential access to such assessments to third parties (160).
Owner:MUNZER MARTIN +3
Process for improved protein expression by strain engineering
ActiveUS20140162279A1Increasing recombinant protein productionReduce energy consumptionMicrobiological testing/measurementFermentationBiotechnologyFusion Protein Expression
This invention is a process for improving the production levels of recombinant proteins or peptides or improving the level of active recombinant proteins or peptides expressed in host cells. The invention is a process of comparing two genetic profiles of a cell that expresses a recombinant protein and modifying the cell to change the expression of a gene product that is upregulated in response to the recombinant protein expression. The process can improve protein production or can improve protein quality, for example, by increasing solubility of a recombinant protein.
Owner:PFENEX
Use of mass labeled probes to detect target nucleic acids using mass spectrometry
InactiveUS20090156424A1Microbiological testing/measurementLibrary screeningBiological bodyMass Spectrometry-Mass Spectrometry
The invention relates to the use of mass labeled probes to characterise nucleic acids by mass spectrometry. Thus the invention provides methods of detecting the presence of a target nucleic acid in a sample, using a circularising probe in which a mass tag is present in the probe. Further methods of detecting the presence of a target nucleic acid are provided, which in contrast use a probe detection sequence in the circularising probe, wherein the probe detection sequence is detected with a probe attached to a mass tag. Methods for determining a genetic profile from the genome of an organism also form part of the invention.
Owner:TRILLION GENOMICS
Method for preparing and using personal and genetic profiles
ActiveUS7089498B1Microbiological testing/measurementData visualisationChemical structureGenetic data
Method and system for preparing a personal genetic profile includes collecting genetic data from an individual, assigning the data to a coordinate system, storing the data, and providing access for retrieval by the individual from whom the genetic data were collected, after receipt of an Identifier that adequately authenticates the identity of the data requester. Locations of genetic markers are provided as three-dimensional coordinates, described with matrix relationships that are consistent with the primary and secondary chemical structure of molecular constituents of a DNA chain for the individual.
Owner:THOMAS XAVIER +9
Sample preparation, processing and analysis systems
ActiveUS20170197213A1Small footprintFast timeHeating or cooling apparatusTransportation and packagingAnalyteAllele
Owner:INTEGENX
Apparatus and method for processing and/or for providing healthcare information and/or healthcare-related information with or using an electronic healthcare record and genetic information and/or genetic-related information
Owner:JOAO RAYMOND ANTHONY +2
Genes and polymorphisms associated with AMD
InactiveUS20100303832A1Decreased and increased riskIncreased riskOrganic active ingredientsSenses disorderCvd riskFhit gene
The invention relates to genes, gene polymorphisms, and genetic profiles associated with an elevated or a reduced risk of alternative complement cascade deregulation disease such as AMD. The invention provides methods and reagents for determination of risk, diagnosis and treatment of such diseases. In an embodiment, the present invention provides methods and reagents for determining sequence variants in the genome of a patient which facilitate assessment of risk for developing such diseases.
Owner:UNIV OF IOWA RES FOUND
System, method and device for making and delivering genetic-based personalized nutrient and supplement mixtures
A system for preparing a genetically-based personalized mixture of nutrients and other ingredients that includes an input device to input genetic information of a user into the system, an identifying device to identify a genetic profile of the user based on the user input information, and a processing device to process the information inputted by the user and identify a mix and concentration of ingredients stored in the system to be prepared based on the genetic profile of the user. The system also includes a mixing device to mix a customized beverage to deliver to the user where the customized beverage includes the mix and concentration of ingredients prepared based on the genetic profile of the user.
Owner:ALPHAGENICS
Genetic Based Health Management Systems for Weight and Nutrition Control
InactiveUS20130151270A1Easy to useEliminate ‘ fuzzy logic ’Data processing applicationsHealth-index calculationNutritionGenotype
Systems have been devised for health management based upon genetic markers. Specifically, systems are arranged to compute genetic risk for several factors relating to metabolism and weight gain in view of various genotypes at particular markers in an individual's genome. An algorithm which depends upon these risk calculations and in further view of the presence of additional variants in the genome under test is executed to arrive at a diet type selection for the particular user. In additions to diet type selections, specific supporting diet related recommendations related to eating behaviors, food reactions and nutritional needs, based upon markers found in the genetic profile, are additionally included in a diet action plan.
Owner:PATHWAY GENOMICS
Methods and materials for determining the source of waste
InactiveUS20130071847A1Bioreactor/fermenter combinationsBiological substance pretreatmentsUnknown SourceDNA
A method for identifying the source of animal waste is provided. The method includes taking DNA samples from a known group of animals, conducting DNA analysis on the DNA samples to prepare a genetic profile for each animal from the group, preparing a database of the genetic profiles, collecting a specimen of waste from an unknown source, conducting DNA analysis on the specimen, and comparing the DNA analysis from the specimen to the database to determine the source of the waste.
Owner:BIOPET VET LAB
Methods of improving genetic profiles of dairy animals and products
The present invention provides methods for improving desirable dairy traits through the use of a genetic profile. Also provided are methods for determining an animal's genotype with respect to multiple markers used in the analysis of the genetic profile. In some embodiments, the genetic profile includes at least one marker associated with the polled trait. The invention also provides methods for selecting or allocating animal for predetermined uses, for picking potential parent animal for breeding, and for producing improved dairy products.
Owner:PFIZER INC
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