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137 results about "Vagal nerve" patented technology

The vagus nerve is so named because it “wanders” like a vagabond, sending out sensory fibers from your brainstem to your visceral organs. The vagus nerve, the longest of the cranial nerves, controls your inner nerve center— the parasympathetic nervous system. ... THE VAGUS NERVE PREVENTS INFLAMMATION. A certain amount of inflammation after injury or illness is normal.

Vagus nerve stimulation via unidirectional propagation of action potentials

Methods of stimulating a vagus nerve include providing at least one implantable stimulator with at least two electrodes, configuring the electrodes to apply stimulation that unidirectionally propagates action potentials along a vagus nerve, and applying the stimulation to the vagus nerve to effectively select afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. At least one of the electrodes comprises a leadsless electrode.
Owner:BOSTON SCI NEUROMODULATION CORP

System and method for providing electrical pulses to the vagus nerve(s) to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders with a stimulator, comprising bi-directional communication and network capabilities

A system and method for providing pulsed electrical stimulation to one or both vagus nerve(s) of a patient to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders. The electrical pulses can be provided either unilaterally or bilaterally (left and right vagus nerves) and can be supra-diaphramatic or be sub-diaphramatic. The system comprising implantable stimulator, lead(s), an external stimulator, and a programmer. The implantable stimulator, comprising a pulse generator module, and a stimulus-receiver module which is used in conjunction with an external stimulator. Control circuitry ensures selective operation of one of the modules of the implanted stimulator, at a time. Further, the external stimulator comprises a telemetry module for remotely activating (or de-activating) programs over the internet, to arrive at the optimal program for each patient. Once the optimal “dose” is titrated using the external stimulator, the implanted pulse generator can then be programmed to similar parameters. The external stimulator in conjunction with the implanted stimulus-receiver can override the implanted pulse generator module, to provide extra dose of therapy, and also to conserve the implanted battery. The external stimulator is networked to other computers. Using the networking, a physician situated remotely can monitor and program the devices, as well as, automatically generate invoicing. In one embodiment, the external stimulator also comprises GPS circuitry for locating patient.
Owner:NEURO & CARDIAC TECH

Controlled vagal blockage therapy

A method for treating at least one of a plurality of disorders characterized at least in part by vagal activity includes positioning an electrode around a body organ innervated by the vagus. An electrical signal is applied to the electrode to modulate vagal activity. The electrical signal is applied at a frequency selected for the signal to create a neural conduction block to the vagus with the neural conduction block selected to at least partially block nerve impulses on the vagus. The application of the electrical signal is discontinued. The application of the signal and the discontinuing of the signal are repeated with durations of the discontinuing and the application selected to treat the disorder.
Owner:RESHAPE LIFESCIENCES INC

High frequency vagal blockage therapy

A method for treating at least one of a plurality of disorders characterized at least in part by vagal activity includes positioning an electrode at a body organ innervated by the vagus. An electrical signal is applied to the electrode to modulate vagal activity. The electrical signal is applied at a frequency in excess of 3,000 Hz for the signal to create a neural conduction block to the vagus with the neural conduction block selected to at least partially block nerve impulses on the vagus.
Owner:RESHAPE LIFESCIENCES INC

Stimulating cranial nerve to treat pulmonary disorder

ActiveUS20070027496A1Spinal electrodesDiseaseRight vagus nerve
A method for stimulating a portion of a vagus nerve of a patient to treat a pulmonary disorder is provided. At least one electrode is coupled to at least one portion of a left vagus nerve and / or a right vagus nerve of the patient. An electrical signal is applied to the portion of the vagus nerve using the electrode to treat the pulmonary disorder. The electrical signal may perform a blocking of an intrinsic neural activity on said at least one portion of the left vagus nerve and said right vagus nerve.
Owner:LIVANOVA USA INC

Vagal nerve stimulation using vascular implanted devices for treatment of atrial fibrillation

An abnormally rapid ventricular cardiac rate that results from atrial fibrillation can be reduced by stimulating a vagal nerve of the heart. An apparatus for such stimulation includes a power transmitter that emits a radio frequency signal. A stimulator, implanted in a blood vessel adjacent the vagal nerve, has a pair of electrodes and an electrical circuit thereon. The electrical circuit receives the radio frequency signal and derives an electrical voltage from the energy of that signal. The electrical voltage is applied in the form of pulses to the pair of electrodes, thereby stimulating the vagal nerve. The pattern of that stimulating pulses can be varied in response to characteristics of the atrial fibrillation or the ventricular contractions.
Owner:KENERGY INC

Gastric constriction device

A gastric constriction device (160) comprises a sheet (131) extending over part of the wall of the stomach (24). Five bands (151) extend around the stomach (24) to fix the sheet (131) in position relative to the stomach (24). The lower two bands (151) extend from the first side (152) of the sheet (131) around the stomach (24) only partially towards the second side (153). These lower two bands (151) are not fixed to the second side (153). This arrangement results in an unconstricted portion of the stomach (161). In this manner, the device (160) restricts expansion of the majority of the stomach wall while facilitating expansion of this unconstricted portion (161). The unconstricted portion (161) is therefore free to expand or bulge outwardly upon ingestion. This expansion may trigger the feeling of satiation due to the presence of the vagal nerves in this portion (161) of the stomach (24).
Owner:PROXY BIOMEDICAL

Vagal nerve stimulation techniques for treatment of epileptic seizures

The present invention uses electrical stimulation of the vagus nerve to treat epilepsy with minimized or no effect on the heart. Treatment is carried out by an implantable signal generator, one or more implantable electrodes for electrically stimulating a predetermined stimulation site of the vagus nerve, and a sensor for sensing characteristics of the heart such as heart rate. The heart rate information from the sensor can be used to determine whether the vagus nerve stimulation is adversely affecting the heart. Once threshold parameters are met, the vagus nerve stimulation may be stopped or adjusted. In an alternative embodiment, the invention may include a modified pacemaker to maintain the heart in desired conditions during the vagus nerve stimulation. In yet another embodiment, the invention may be simply a modified pacemaker having circuitry that determines whether a vagus nerve is being stimulated. In the event that the vagus nerve is being stimulated, the modified pacemaker may control the heart to maintain it within desired conditions during the vagus nerve stimulation.
Owner:OSORIO IVAN +1

Systems and methods for implantable leadless nerve stimulation

Systems and methods are disclosed to stimulate nerves to treat medical conditions such as pain, and other conditions, such as, CHF, obesity, incontinence, etc., that could be controlled by the stimulation of the vagal nerves. The invention uses electrical stimulation of the nerve, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined nerve site. The vibrational energy is generated by a controller-transmitter, which could be implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on or around the nerve that needs to be stimulated. The implantable receiver-stimulator stimulates different nerves and regions of a nerve to provide therapeutic benefit.
Owner:EBR SYST

Neural stimulation devices and systems for treatment of chronic inflammation

A system for treating chronic inflammation may include an implantable microstimulator, a wearable charger, and optionally an external controller. The implantable microstimulator may be implemented as a leadless neurostimulator implantable in communication with a cervical region of a vagus nerve. The microstimulator can address several types of stimulation including regular dose delivery. The wearable charger may be worn around the subject's neck to rapidly (<10 minutes per week) charge an implanted microstimulator. The external controller may be configured as a prescription pad that controls the dosing and activity of the microstimulator.
Owner:SETPOINT MEDICAL CORP

Device and Method for Treating Weight Disorders

An apparatus and a method for treating a weight disorder in a subject are provided. The apparatus comprising an implantable device such as an inflatable balloon and electrodes capable of sensing a physiological change associated with food ingestion or hunger and a mechanism adapted for directly stimulating a region such as the duodenum which is responsive to a gastrointestinal satiety agent, such a mechanism can be a drug reservoir containing a drug such as CCK or analogs thereof which is contained within an inflatable balloon being implantable in a stomach of the subject. The apparatus and method provided here combine synergistic approaches to limiting meal size, i.e., chemo and mechano receptor activation of vagal satiety stimuli, electric stimulation of specific vagal pathways and limitations of gastric space.
Owner:DUOCURE

Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s)

A method and system to provide pre-determined electrical pulses for neuromodulating vagus nerve(s) or its branches to provide therapy for bulimia / eating disorders, comprises implantable and external components. The electrical pulses to vagus nerve(s) may be stimulating and / or blocking. The pulsed electrical stimulation / blocking to vagus nerve(s) may be provided using one of the following stimulation systems, such as: a) an implanted stimulus-receiver with an external stimulator; b) an implanted stimulus-receiver comprising a high value capacitor for storing charge, used in conjunction with an external stimulator; c) a programmer-less implantable pulse generator (IPG) which is operable with a magnet; d) a microstimulator; e) a programmable implantable pulse generator; f) a combination implantable device comprising both a stimulus-receiver and a programmable implantable pulse generator (IPG); and g) an implantable pulse generator (IPG) comprising a rechargeable battery. In one embodiment, the external components such as the programmer or external stimulator may comprise a telemetry means for networking. The telemetry means therefore allows for interrogation or programming of implanted device, from a remote location over a wide area network.
Owner:NEURO & CARDIAC TECH

Method and system to provide therapy or alleviate symptoms of involuntary movement disorders by providing complex and/or rectangular electrical pulses to vagus nerve(s)

A method and system for providing rectangular and / or complex electrical pulses for neuromodulating vagus nerve(s) and / or its branches, to provide therapy for involuntary movement disorders (including Parkinson's disease and epilepsy), comprises implantable and external components. Complex electrical pulses comprises pulses which are configured to be one of non-rectangular, multi-level, biphasic, or pulses with varying amplitude during the pulse. The electrical pulses to vagus nerve(s) may be stimulating and / or blocking. The stimulation and / or blocking to vagus nerve(s) may be provided using one of the following pulse generation means: a) an implanted stimulus-receiver with an external stimulator; b) an implanted stimulus-receiver comprising a high value capacitor for storing charge, used in conjunction with an external stimulator; c) a programmer-less implantable pulse generator (IPG) which is operable with a magnet; d) a microstimulator; e) a programmable implantable pulse generator; f) a combination implantable device comprising both a stimulus-receiver and a programmable implantable pulse generator (IPG); and g) an implantable pulse generator (IPG) comprising a rechargeable battery. The pulse generator means comprises predetermined / pre-packaged programs. In one embodiment, the pulse generation means may also comprise telemetry means, for remote interrogation and / or programming of said pulse generation means utilizing a wide area network.
Owner:BOVEJA BIRINDER R +1

Method of using endoscopic truncal vagoscopy with gastric bypass, gastric banding and other procedures

Methods and devices for treating obesity by combining known bariatric surgeries with a method for disrupting the vagal nerve. The method for disrupting the vagal nerve comprises use of a high energy delivery device which is positioned within the esophagus to deliver transesophageal energy to interrupt the function of one or both branches of the vagal nerves. Combination of this method with known methods, such as gastric bypass and gastric banding, may increase weight loss by the patient in comparison to a single treatment on its own. In addition, methods and devices for disposing a restrictive structure such as a mesh around a selected segment of the gastrointestinal tract prevents enlargement of the segment.
Owner:ENDOVX

Vagus nerve stimulation via unidirectional propagation of action potentials

Methods of using unidirectionally propagating action potentials (UPAPs) for vagus nerve stimulation and for certain disorders are provided. Stimulators capable of creating such UPAPs include, but are not limited to, miniature implantable stimulators (i.e., microstimulators), possibly with programmably configurable electrodes.
Owner:BOSTON SCI NEUROMODULATION CORP

Method and system for providing therapy for bulimia/eating disorders by providing electrical pulses to vagus nerve(s)

A method and system to provide pre-determined electrical pulses for neuromodulating vagus nerve(s) or its branches to provide therapy for bulimia / eating disorders, comprises implantable and external components. The electrical pulses to vagus nerve(s) may be stimulating and / or blocking. The pulsed electrical stimulation / blocking to vagus nerve(s) may be provided using one of the following stimulation systems, such as: a) an implanted stimulus-receiver with an external stimulator; b) an implanted stimulus-receiver comprising a high value capacitor for storing charge, used in conjunction with an external stimulator; c) a programmer-less implantable pulse generator (IPG) which is operable with a magnet; d) a microstimulator; e) a programmable implantable pulse generator; f) a combination implantable device comprising both a stimulus-receiver and a programmable implantable pulse generator (IPG); and g) an implantable pulse generator (IPG) comprising a rechargeable battery. In one embodiment, the external components such as the programmer or external stimulator may comprise a telemetry circuit for networking. The telemetry circuit therefore allows for interrogation or programming of implanted device, from a remote location over a wide area network.
Owner:NEURO & CARDIAC TECH

Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

A non-invasive electrical stimulator shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in contact with the electrodes. The conducting medium is also in contact with an interface element that may conform to the contour of a target body surface of the patient when the interface element is applied to that surface. When the interface element is made of insulating (dielectric) material, and disclosed stimulation waveforms are used, the power source need not supply high voltage, in order to capacitively stimulate the target nerve. The stimulator is configured to produce a peak pulse that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie in the vicinity of the target nerve and patient's skin.
Owner:ELECTROCORE

System and method for providing electrical pulses to the vagus nerve(s) to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders with a stimulator, comprising bi-directional communication and network capabilities

A system and method for providing pulsed electrical stimulation to one or both vagus nerve(s) of a patient to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders. The electrical pulses can be provided either unilaterally or bilaterally (left and right vagus nerves) and can be supra-diaphramatic or be sub-diaphramatic. The system comprising implantable stimulator, lead(s), an external stimulator, and a programmer. The implantable stimulator, comprising a pulse generator module, and a stimulus-receiver module which is used in conjunction with an external stimulator. Control circuitry ensures selective operation of one of the modules of the implanted stimulator, at a time. Further, the external stimulator comprises a telemetry module for remotely activating (or de-activating) programs over the internet, to arrive at the optimal program for each patient. Once the optimal “dose” is titrated using the external stimulator, the implanted pulse generator can then be programmed to similar parameters. The external stimulator in conjunction with the implanted stimulus-receiver can override the implanted pulse generator module, to provide extra dose of therapy, and also to conserve the implanted battery. The external stimulator is networked to other computers. Using the networking, a physician situated remotely can monitor and program the devices, as well as, automatically generate invoicing. In one embodiment, the external stimulator also comprises GPS circuitry for locating patient.
Owner:NEURO & CARDIAC TECH

Selective neurostimulation for treating epilepsy

A method and device for treating epilepsy are disclosed which provide for electrical, chemical or magnetic stimulation of certain areas of the brain to modulate neuronal activity of areas associated with symptoms of epilepsy. Deep brain stimulation is combined with vagus nerve stimulation to enhance symptomatic relief of the disorder. Some embodiments also employ a sensing capability to optimize the therapeutic treatment regimen.
Owner:LIVANOVA USA INC

Devices and Methods for Screening of Vagal Nerve Stimulation

InactiveUS20100286553A1Good effectElectroencephalographySensorsRight carotid sheathSacral nerve stimulation
The present disclosure provides systems and methods for screening vagus nerve stimulation to determine the potential efficacy of permanent stimulation systems. In one aspect, the system includes temporary electrode assemblies adapted for temporary placement on or in the body adjacent the vagus nerve. In another aspect, a method is provided to place a stimulating electrode adjacent the posterior of the carotid sheath.
Owner:DECAF

Method and system for providing therapy for migraine/chronic headache by providing electrical pulses to vagus nerve(s)

A method and system for providing predetermined electrical pulses for neuromodulating vagus nerve(s) or its branches to provide therapy for migraine / chronic headache, comprises implantable and external components. The electrical pulses to vagus nerve(s) may be stimulating and / or blocking. The pulsed electrical stimulation / blocking to vagus nerve(s) may be provided using one of the following stimulation systems, such as: a) an implanted stimulus-receiver with an external stimulator; b) an implanted stimulus-receiver comprising a high value capacitor for storing charge, used in conjunction with an external stimulator; c) a programmer-less implantable pulse generator (IPG) which is operable with a magnet; d) a microstimulator; e) a programmable implantable pulse generator; f) a combination implantable device comprising both a stimulus-receiver and a programmable implantable pulse generator (IPG); and g) an implantable pulse generator (IPG) comprising a rechargeable battery. The pulse generator system comprises predetermined / pre-packaged programs. In one embodiment, the external components such as the programmer or external stimulator may comprise a telemetry means for networking. The telemetry means therefore allows for interrogation or programming of implanted device, from a remote location over a wide area network.
Owner:BOVEJA BIRINDER R +1

Method and apparatus for detecting vagus nerve stimulation

A method and apparatus for monitoring the application of a vagus nerve stimulation signal includes a detection circuit having an amplifier, a filter, and a signal prolongation circuit. The signal prolongation circuit rectifies a detected vagus nerve signal and provides the signal to a Schmitt trigger extending the length of the signal. Because of the prolongation of the signal, the signal can be sampled at a relatively low rate, and real time data illustrating the response of various physiological signals to the application of the vagus nerve signal can be monitored, thereby providing clinical data for monitoring and adjusting the applied stimulation.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Methods and apparatus for treatment of obesity with an ultrasound device movable in two or three axes

Method and apparatus for treating obesity by an energy delivery device, such as a high focus ultrasound transducer, mounted for movement along two or three axes relative to the esophagus to deliver transesophageal energy to interrupt the function of vagal nerves. Preferably, movement along a longitudinal axis of the esophagus changes the site to which the energy is directed and movement transversely along a radius of the esophagus focuses the energy on a vagal nerve. The third degree of freedom relative to the esophagus is to rotate the transducer about the longitudinal axis of the esophagus.
Owner:ENDOVX

Novel method for the adjustment of human and animal vagus nerve stimulation

The present invention relates to vagus nerve stimulation techniques and more particularly to techniques for providing a more effective monitoring of vagus nerve stimulation and for the adjustment of vagus nerve stimulation (VNS). Specifically, the present invention relates to methods for adjusting and controlling the vagal nerve stimulation (VNS) signal induced by a stimulus generator. The method of the invention takes advantage of monitoring respiratory parameters which correspond to the VNS intensity, whereby the stimulation intensity is set in response to the respiratory parameter.
Owner:NEUROTRONICS

Methods and apparatus for treatment of obesity

Method and apparatus for treating obesity by use of transesophageal delivery of energy to interrupt the function of vagal nerves. The energy, which may be highly focused ultrasound energy or other types of energy is delivered through the wall of the esophagus by a device placed in the esophagus. The energy delivered is sufficient to ablate a vagal nerve on the outer wall of the esophagus.
Owner:ENDOVX
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