8results about How to "Improve limitations" patented technology

The present application relates to the field of pharmaceutical preparations, in particular to a long-acting eye composite preparation for improving the symptoms of blepharitis. The preparation comprises a combination of two active ingredients in a therapeutically effective amount, and one or more ion-sensitive polymers or their complex systems, which are used to treat the symptoms of blepharitis caused by Demodex through a special double-cavity drug delivery bottle. By using a specific ion gel matrix concentration and regulating the viscosity of the drug solution before it reaches the eye, the limitations of traditional eye preparations are overcome, the retention time of the drug in the eye is prolonged, the bioavailability is improved, the probability of adverse events is reduced, and the medication compliance is increased.

The application discloses a kind of for the method, device, equipment and medium of tab abnormality detection in battery cell production process, comprising: the tab area image collected in battery cell production process is segmented to generate tab mask;Based on the tab mask extraction multi-scale pixel-level feature vector, and the multi-scale pixel-level feature vector is input into unsupervised probability GMM model to identify pixel-level abnormal point;The pixel-level abnormal point is analyzed to obtain candidate abnormal area, and the parameter index of the candidate abnormal area is obtained;Determine whether the parameter index meets the set tab abnormality judgment rule, if meet, it is judged as tab abnormality, and tab abnormality result is output.Therefore, the application can be widely applied to the detection of tab folding, crease, fracture, misplacement and other abnormalities on battery cell production line.

This invention discloses a method for identifying land cover in highly heterogeneous areas. The method includes: collecting heterogeneous historical land cover products of the target area and obtaining stable regions of different cover types through overlay analysis; dividing the target area into blocks based on its latitude and longitude information with a spatial constraint of 1°×1°, then setting three thresholds of 50, 70, and 100, and using a stratified sampling strategy to obtain uniformly distributed sample data of the target area; acquiring temporal optical, radar, and digital elevation data of the target area, and addressing the influence of clouds and rain through data synthesis; and finally constructing a tile-based classification model for classification. The tile-based classification model constructed in this invention addresses the heterogeneity of plateau regions, fully considering the similarity of adjacent land features and the large climate span of the plateau. Simultaneously, a strategy for stable, rapid, and uniform sample data generation is developed, saving material and financial resources. The mapping results provide data support for ecological civilization construction and biodiversity conservation.

This invention discloses a novel method and system for constructing a three-dimensional numerical model of the foot and shoe. The method first acquires foot and shoe data from a subject wearing footwear in three postures: toe-landing, static standing, and heel-landing, using spiral CT scans. Based on the acquired scan data, and after mesh generation and material property assignment, a three-dimensional finite element numerical model of the foot and shoe is established. Static simulations are performed by inputting different ligament elastic moduli and Poisson's ratio parameters into the three-dimensional finite element numerical model of the foot and shoe, and setting boundary conditions for the corresponding postures, to obtain simulated values ​​of peak pressure on the sole and shoe sole and deformation in specific areas. Simultaneously, physical tests are conducted to obtain measured values. Error analysis is performed between the simulated and measured values, and the optimal set of parameters with the smallest total error is selected by adjusting the ligament parameters to construct a standard three-dimensional numerical model of the foot and shoe. This invention combines multi-posture mechanical response and ligament parameter optimization to achieve high-precision verification and correction of the foot and shoe model.

This invention relates to the fields of biomedical technology and pharmaceutical formulations, and discloses a sustained-release powder spray for oral ulcers based on milk exosomes and its preparation method. The spray uses milk exosomes as the active ingredient, combined with an extracellular matrix-simulated network composed of sodium hyaluronate and collagen, and the stabilizer trehalose. It is prepared into a dry powder with a particle size of 2-15 μm through a microdroplet freeze-drying process. During preparation, the components are mixed and formed into microdroplets using a microfluidic device, then instantaneously frozen in liquid nitrogen at -80°C, and finally freeze-dried to obtain the powder. This formulation can be stably stored for a long time at 2-8°C. When used, it is sprayed onto the ulcer surface using a quantitative spray device. Upon contact with moisture, the gel network is reconstructed in situ, achieving sustained release and protection of the exosomes. It has the advantages of convenient use, accurate dosage, and long-lasting healing promotion.

This invention relates to an integrally woven pile sandwich mesh fabric and its weaving method. The integrally woven pile sandwich mesh fabric is woven in one piece using a warp knitting machine equipped with no fewer than seven ground comb bars. It includes a face layer, a middle layer, and a bottom layer. The face layer is woven using the chain blocks of the jacquard or ground comb on the machine in any weave pattern. The middle layer is woven using yarns connected to the face and bottom layers in a weave pattern. The bottom layer is woven using the chain blocks of the jacquard or ground comb on the machine in any weave pattern. This invention, through reasonable process design of each comb bar, fully utilizes the advantages of jacquard and ground combs, combines the variations in yarn threading of the comb bars, and employs precise design and the use of synthetic fibers to produce an integrally woven sandwich three-dimensional pile mesh fabric with characteristics of being skin-friendly and soft, lightweight, high-performance, and structurally stable.

This application discloses an image filtering method, apparatus, electronic device, and computer storage medium. The method calculates pixel values ​​of a target image using multiple filters in a preprocessing sub-model of the image filtering model to obtain a residual image. This residual image is then input into a filtering sub-model of the image filtering model. The filtering sub-model uses convolution kernels and a general feature extractor to calculate multiple statistical features, which are then used to determine the filtering result of the target image. By using multiple filters, the limitations of using a single filter to capture the dependencies between adjacent pixels are avoided, allowing for better capture of these dependencies and thus better understanding of the impact of secondary processing on the image. The multiple statistical features output by the filtering sub-model determine the filtering information used to indicate whether the target image has been modified, thereby improving the efficiency of the image filtering method.