43 results about "Tumor suppressor gene" patented technology

A tumor suppressor gene, or antioncogene, is a gene that regulates a cell during cell division and replication. If the cells grow uncontrollably it could result in cancer. When a tumor suppressor gene is mutated it results in a loss or reduction in its function; in combination with other genetic mutations this could allow the cell to grow abnormally. The loss of function for these genes may be even more important than proto-oncogene/oncogene activation in the development of many different human cancer cells. Tumor suppressor genes can be grouped into categories including caretaker genes, gatekeeper genes, and landscaper genes; the classification schemes are evolving as medicine advances, learning from fields including molecular biology, genetics, and epigenetics.