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5 results about "Hydrolase inhibitor" patented technology

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AdOx is an AdoHcy hydrolase inhibitor that causes the accumulation of intracellular AdoHcy levels. This increase in AdoHcy levels results in feedback inhibition of most methylation reactions. MTA, a nucleoside inhibitor of methyltransferases, blocks the transfer of methyl groups from AdoMet to PRMT substrates.