81 results about "Transcatheter aortic" patented technology

Inflatable medical devices and methods for making and using the same are disclosed. The devices can be medical invasive balloons, such as those used for transcutaneous heart valve implantation, such as balloons used for transcatheter aortic-valve implantation. The balloons can have high strength, fiber-reinforced walls.

A guide catheter (30) is described for introduction into a patient's vasculature, to provide a substantially continuous guide lumen (28) within the vasculature to the ascending aorta (34), through which one or more other functional catheters (44) may be introduced and removed during the procedure. The guide catheter includes an aligner (70) at its distal region for aligning the position and/or inclination of the distal region of the guide catheter with respect to the ascending aorta. The aligner includes an embolic protection filter (88). The guide catheter is made of material collapsible/distensible in cross section to adopt a small shape when no catheter is present inside, and to distend to a large shape to accommodate passage of functional catheter therethrough. The cross-section shape collapses/distends by folding/unfolding of material without elastic stretching of the material.

The invention is a prosthetic device for improving function of a mitral valve. The device includes a sealing member configured for positioning between mitral valve leaflets. The device also includes an expandable anchor frame configured to be positioned within one or more heart chambers, for maintaining the sealing member at a desired position between valve leaflets. The sealing member reduces mitral regurgitation be filling the gap that can occur between opposing leaflets of a damaged mitral valve, thus restoring proper mitral valve closure.

A clip used to repair the tissue of a heart valve leaflet may include a shaft having a barb and a plurality of legs connected to the shaft. The plurality of legs may extend away from the barb in a first condition, and may extend towards the barb in a use condition. The clips may be delivered to the heart valve leaflet and applied to the same in a minimally invasive procedure using a transcatheter device. The device may be used to apply a single clip to the leaflet tissue or multiple clips.

A transcatheter atria-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.

An atrial sealing skirt for transcatheter valves and an atrial sealing skirt with an integrated valve to reduce paravalvular regurgitation, with or without the presence of intracardiac leads. The atrial sealing skirt includes a top brim which is positioned to conform to the atrial floor at the deployment site.

A method (10) to compensate for cardiac and respiratory motion in cardiac imaging during minimal invasive (e.g., trans-catheter) AVI procedures by image-based tracking (20, 25) on fluoroscopic images.

A method and system for transcatheter aortic valve implantation (TAVI) planning is disclosed. An anatomical surface model of the aortic valve is estimated from medical image data of a patient. Calcified lesions within the aortic valve are segmented in the medical image data. A combined volumetric model of the aortic valve and calcified lesions is generated. A 3D printed model of the heart valve and calcified lesions is created using a 3D printer. Different implant device types and sizes can be placed into the 3D printed model of the aortic valve and calcified lesions to select an implant device type and size for the patient for a TAVI procedure. The method can be similarly applied to other heart valves for any type of heart valve intervention planning.

A medical assembly and methods for endovascularly implanting a valve in the heart having a valve and an anchor assembly for positioning and restraining the valve. An anchor delivery system introduces and implants the anchor into the implantation site and a valve delivery system introduces and seals the valve at the deployment site. The present invention also relates to methods of implantation of the medical assembly and the valve.

A preformed guidewire particularly well-suited for use in percutaneous medical procedures, such as transcatheter aortic valve replacement, includes an inner corewire of discontinuous, tapered stiffness that is surrounded along a portion of its length by a flexible, outer casing of uniform cross-section, such as a tightly wound, stainless steel, spring coil wire. The inner corewire is constructed of a shape-memory material, such as a nickel-titanium alloy, that is preformed into an encircled S-shaped configuration in its atraumatic distal region. Specifically, the distal region includes an enlarged, stiffened, proximate segment that encircles a smaller, more flexible, distal segment. As a feature of the invention, the distal and proximal segments project along fixed-radial arcuate paths that extend in opposite directions from one another. As a result, the distal region is optimally configured to limit the risk of trauma to the immediate site of treatment when inserted through a straightened guide catheter.

A catheter for positioning a valve during a transcatheter aortic valve replacement is formed from a resilient hollow body conformable to a guide wire when a guide wire is passed in through an upper opening in the hollow body and through the hollow body. When the guide wire is retracted, the catheter deploys to form a substantially straight upper shaft portion that extends downwardly from the upper opening and a distal ring perpendicular to the upper shaft portion. The distal ring approximates the size and shape of the patient's aortic valve annulus. A lower loop connects the upper shaft portion of the catheter to the distal ring. An outer surface of the distal ring is radiopaque, and the distal ring comprises openings for dispersing radio opaque medium used in imaging of the patient's aortic valve annulus. The deployed catheter is retracted until it snugly contacts the aortic valve annulus. The distal ring will be viewed as a straight line when the x-ray C-arm is properly aligned with the aortic valve annulus.

An intracorporeal device for delivery into a patient is provided. The intracorporeal device includes a proximal end and a distal end. The distal end is detachably coupled from the transcatheter delivery device. The device relates to a transcatheter system and corresponding devices and methods of treatment, and is particularly useful for the delivery and implantation into the body of a patient of medical devices, such as mechanical circulatory support devices, but also has a wider variety of applications.

Under one aspect of the present invention, a system for performing renal denervation in a patient having an aorta and a renal artery and a branchpoint therebetween includes a flexible catheter comprising a main section, first and second arms, and a bifurcation between the first and second arms, the main section having a proximal end and a distal end, the distal end configured to be disposed in the aorta, the first arm being coupled to the distal end of the main section and configured to be disposed in the renal artery, the second arm being coupled to the distal end of the main section and configured to be disposed in the aorta, the bifurcation between the first and second arms being configured to engage the branchpoint between the aorta and the renal artery.

A system and apparatus comprising a multisensor guidewire for use in interventional cardiology, e.g. for Transcatheter Valve Therapies (TVT), comprises a plurality of optical sensors for direct measurement of cardiovascular parameters, e.g. transvalvular blood pressure gradients and flow. A conventional outer coil contains a shaped core wire having a cross-section defining helical grooves extending along its length, which accommodate optical fibers and optical sensors within a diameter D_core of the core wire. Advantageously, the diameter and material of the core wire provides the guidewire with sufficient stiffness for use as a support guidewire for valve replacement, e.g. Transcatheter Aortic Valve Implantation (TAVI), while accommodating multiple sensors and optical fibers within a guidewire of outside diameter ≦0.89 mm. An optical connector couples the guidewire to a control system. Optionally, the guidewire includes a contact force sensor; a pre-formed tip; and/or a separable micro-connector for proximal mounting of over-the-guidewire components.

A delivery device for a collapsible prosthetic heart valve includes a support shaft around which a compartment for the valve is defined, a distal sheath adapted to selectively cover and uncover the compartment and the valve, and a marker cage having a collapsed condition when the distal sheath covers the compartment and an expanded condition when the compartment is uncovered. The marker cage includes at least one rib having a radiopaque marker for determining the positioning of the valve as it is deployed. The valve may be assembled around the marker cage so that the marker cage does not interfere with the radial expansion of the valve during deployment.

A delivery device (100) includes a support member (128), a distal sheath (130), an outer shaft (120) and a strengthening member (140). The support member is adapted to hold a prosthetic heart valve. The distal sheath is slidable relative to the support member between a first position in which the distal sheath is adapted to maintain the prosthetic heart valve in a collapsed condition, and a second position in which the distal sheath is adapted to expose the prosthetic heart valve. The outer shaft is connected to the distal sheath and has a curved portion (134). The straightening member is slidable on the outer shaft between a proximal position in which the straightening member does not cover the curved portion of the outer shaft, and a distal position in which the straightening member covers and substantially straightens at least a portion of the curved portion of the outer shaft.

The invention discloses an artificial aortic valve ring system, which is used for taking effects of supporting and fixing in trans-catheter aortic valve replacement on patients of aortic valve regurgitation without calcification. The system comprises a valve ring scaffold at distal end and anchoring legs at proximal end, wherein the valve ring scaffold is fixedly connected to the anchoring legs; the valve ring scaffold is of a tubular structure and has a gridding structure; the anchoring legs are arranged along the periphery of the valve ring scaffold and are embedded in a cavity structure on ascending aortic root so as to fix the system; and the system is capable of transforming between a first form of radial expansion and a second form of radial shrinkage. With the implantation of the system, the trans-catheter aortic valve replacement on patients of aortic valve regurgitation without calcification becomes possible.

A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base and a restrictive distal opening which is stretchable to larger sizes. A self-expanding frame is attached to the proximal base of the membrane for securing the membrane within the pulmonary artery.

In various embodiments, provided herein are methods, devices and systems to optimize annular orientation of transcatheter valves and thereby facilitate transcatheter aortic valve replacement in the setting of challenging cardiovascular anatomy. These methods, devices and systems are used to treat patients with valvular diseases. To solve these problems, described herein is a Device to Optimize aNnUlar orientation of Transcathether valves (DONUT). DONUT can correct large differences between a native valve's anatomical dimensions and the external dimensions of a transcatheter valve stent frame.