256 results about "Vitamine e" patented technology

The invention belongs to the technical field of gene engineering, and particularly relates to fusion vitamin D hydroxylase and application thereof in preparation of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3. The fusion vitamin D hydroxylase comprises a Vdh-K1 heme structural domain of which the amino acid sequence is shown as SEQ ID NO.1, a CYP116B65 redox structural domain of which the amino acid sequence is shown as SEQ ID NO.3, and a linker for connecting the Vdh-K1 heme structural domain and the CYP116B65 redox structural domain. The fusion vitamin D hydroxylase is a self-sufficiency enzyme, and can realize stable catalytic conversion of vitamin D2 and vitamin D3 on the premise of not depending on an Fdx and Fdr assisted electron transfer system.

The invention relates to the technical field of flammulina velutipes planting, in particular to a flammulina velutipes culture method and compost, which comprises the following steps: S1, preparing purple sweet potato water; the preparation method comprises the following steps: washing fresh purple sweet potatoes, mixing with water in proportion, boiling, cooling, filtering, and taking filtrate as purple sweet potato water for later use; s2, preparing a culture material; the raw materials comprise corncobs, rice bran, bran, cottonseed hulls, sugar beet pulp, soybean hulls, corn flour, brewer's grains, calcium carbonate and shellfish fossils. The preparation method comprises the following steps: weighing solid raw materials in proportion, stirring the raw materials in a stirrer for 10 minutes to obtain a mixture, uniformly mixing the mixture, adding the purple sweet potato water prepared in the step S1, fully stirring the mixture until the mixture is uniformly mixed, and controlling the water content of a final culture material to be 62-68% to obtain the culture medium. The purple sweet potato water is used for completely replacing tap water to serve as a culture material component, the purple sweet potato water is not only a solvent, but also a natural nutrient solution rich in anthocyanin, polysaccharide, vitamins and mineral substances, flammulina velutipes hyphae can absorb and convert the substances, and the anthocyanin content in sporocarp is remarkably increased.

The invention relates to the technical field of functional food preparation, in particular to an instant sugar-free vitamin mineral composition and a preparation method thereof. The composition comprises vitamin microcapsule powder, vitamin mineral particles, maltodextrin and a food additive. The composition is prepared by a three-step method comprising the following steps: firstly, preparing fat-soluble vitamin, natural colloid, protein and the like into microcapsules; carrying out superfine grinding on water-soluble vitamins and mineral substances, granulating with maltodextrin and the like, and controlling the particle size of particles; and finally, mixing the components in proportion. Sugar-free wall materials such as natural vegetable gum, protein and fibers are adopted, traditional saccharides are not used, and the sugar-free wall materials have good instant solubility, dispersity and stability, can effectively cover bitter taste and metal taste of vitamins and mineral substances, are suitable for different people, especially people needing sugar control, and achieve comprehensive, stable and easy-to-absorb nutritional supplement.

The invention provides a feed premix for improving chicken quality. The fresh-keeping agent is prepared from the following components in percentage by weight: 5%-15% of a flavor enhancing component, 10%-25% of a tenderness improving component, 3%-10% of an antioxidant fresh-keeping component, 2%-3% of a function enhancing component and the balance of a carrier and a diluent, the function strengthening component is prepared from beta-alanine embedded citronella essential oil and konjac glucomannan zymolyte; the flavor enhancing component comprises a rosemary extract, a yeast culture and curcumin in a mass ratio of (2-4): (1-3): 1; the tenderness improving component comprises conjugated linoleic acid, L-carnitine modified by glutamine transaminase and betaine in a mass ratio of (3-5): (2-4): 1; the antioxidant fresh-keeping component is vitamin E and tea polyphenol in a mass ratio of (1-2): 1. Through multi-component synergism and functional targeting optimization, a three-dimensional quality improvement system with enhanced flavor, improved tenderness, oxidation resistance and fresh keeping is constructed, so that the chicken quality is comprehensively upgraded.

The invention discloses a qualitative and quantitative detection method for vitamin A and vitamin E in food. The qualitative and quantitative detection method comprises the following steps: step 1, pre-treating a sample and accurately adding an isotope internal standard: adding d6-alpha-tocopheryl acetate and d8-retinol acetate into the sample before saponification and preparing a blank matrix; 2, pre-treatment parameter QbD-DOE collaborative optimization, wherein a response surface method is adopted for conducting center composite design on the saponification temperature, time and BHT concentration, and the interaction effect of all the factors is analyzed to determine an optimal operation window; step 3, intelligently optimizing chromatography-mass spectrometry conditions and tuning parameters; step 4, constructing a matrix matching calibration curve and performing WLS quantitative analysis: performing gradient dilution on a standard substance by utilizing a blank matrix extracting solution, adding an isotope internal standard to prepare a 5-7-point matrix matching calibration curve, fitting the curve by adopting a weighted least square method, and verifying the correlation and intercept change of the calibration curve every day; and 5, multi-dimensional qualitative confirmation and intelligent diagnosis system operation.

This invention discloses a cardioprotective compound composition and its preparation based on improving the absorption rate of coenzyme Q10, relating to the fields of pharmaceuticals and functional foods. The core active ingredients of this composition consist of coenzyme Q10, vitamin E, and black pepper extract, with a specific mass ratio range for each. It can also be combined with pharmaceutically acceptable carriers and antioxidant synergists to prepare various oral formulations. This invention, through the construction of a ternary active component with a specific ratio, achieves in vivo synergistic effects on absorption promotion and antioxidant regeneration, solving the technical problems of low oral bioavailability and insufficient accumulation of myocardial-targeted activity in existing coenzyme Q10 preparations. It significantly improves the conversion efficiency of coenzyme Q10 into a usable active form for cardiomyocytes and can be widely applied in the preparation of drugs and functional foods for the prevention or treatment of heart diseases.

The invention relates to the technical field of preparation of health-care products, in particular to a fat-soluble component nano-emulsion and a preparation method thereof. The preparation method comprises the following steps: stirring and dissolving the antioxidant and the caprylic / capric triglyceride, adding the vitamin D3 and the retinyl palmitate, and stirring and dissolving to obtain an oil phase; stirring the starch sodium octenylsuccinate in purified water until the starch sodium octenylsuccinate is dissolved, adding glycerol, and uniformly stirring and mixing to obtain a water phase; adding a small amount of water phase into the oil phase, and stirring at high speed to obtain primary emulsion; adding the primary emulsion into the residual water phase, stirring at a high speed, shearing and homogenizing to obtain a nano embedding emulsion; adding citric acid, cane sugar and sodium ascorbate into purified water, adding the nano embedding emulsion, and uniformly stirring to obtain a concentrated solution; and diluting the concentrated solution and adjusting the pH value to obtain the fat-soluble component nano-emulsion. The fat-soluble component nano-emulsion provided by the invention has good safety; the product can be easily absorbed and utilized by a human body, and is convenient for people to quickly supplement vitamin A and vitamin D3 required by the body.

The invention relates to the field of detection, in particular to a method for simultaneously detecting multiple fat-soluble vitamins, which comprises the following steps: (S.1) carrying out protein precipitation and liquid-liquid extraction on a sample to be detected to obtain an extract containing fat-soluble vitamins; (S.2) carrying out derivatization reaction on the extract by using a PTAD derivatization reagent; and (S.3) analyzing the derivatized product by adopting a liquid chromatography-tandem mass spectrometry method, wherein the detected target fat-soluble vitamins comprise vitamin A, vitamin E, 25-hydroxy vitamin D2, 25-hydroxy vitamin D3, vitamin K1, vitamin K2 and vitamin K2. According to the application, PTAD is creatively adopted as a unified derivatization reagent, simultaneous and efficient derivatization of seven fat-soluble vitamins is successfully realized, the detection sensitivity of low-content targets, especially vitamin D, K2 and the like, is greatly improved, and the core problems of weak signal response and difficulty in accurate quantification are solved.

The present invention provides a homocysteine-reducing composition that rapidly lowers blood homocysteine ​​levels to an appropriate level without causing any concerns about side effects. [Solution] A composition for reducing homocysteine ​​levels, comprising one or more B vitamins selected from vitamin B6, vitamin B12, and folic acid, and β-NMN as active ingredients. The β-NMN content is in the range of 22.32% to 89.29% by weight. Vitamin C and vitamin B2 may also be added.

The application provides probiotic oral burst balls and a preparation process, and belongs to the technical field of probiotic embedding. The probiotic oral burst balls comprise core materials and wall materials. The core materials comprise probiotic raw materials, a flavoring agent, mannose, xylitol, mannose oligosaccharide, glycine, vitamin E and a solvent 1, and the solvent 1 is an oily solvent. The wall materials comprise trehalose, gelatin, cyclic dextrin and a solvent 2, and the solvent 2 is an oily solvent. The probiotic oral burst balls prepared by the preparation process have the characteristics of temperature resistance, acid resistance and storage resistance.

The invention relates to the technical field of treatment of eczema-like skin symptoms, in particular to an essential oil composition for treating eczema-like skin symptoms and application thereof, and the essential oil composition comprises the following components in parts by weight: 10-20 parts of lavender essential oil, 5-10 parts of tea tree essential oil, 30-40 parts of olive oil, 5-10 parts of squalane, 0.5-1 part of vitamin E and 1-5 parts of plant extract. The lavender essential oil and the tea tree essential oil are compounded, and the olive oil, the squalane, the vitamin E and the plant extract are supplemented, so that symptoms such as skin erythema, papule and pruritus caused by eczema can be effectively relieved, and good anti-inflammatory, antibacterial, moisturizing and repairing effects are achieved. The composition has the advantages of simple components, simplified preparation process, low production cost and wide application range, and can better meet clinical requirements.

The invention provides a soft capsule helpful for improving the function of chloasma as well as a preparation method and application thereof, and relates to the technical field of health care products. The soft capsule comprises a mulberry leaf extract, a seville orange flower extract, a grape seed extract, an almond extract, donkey-hide gelatin powder, vitamin C and vitamin E. The soft capsule provided by the invention exerts the overall effect of improving chloasma through a multi-target synergistic mechanism from inside to outside: the mulberry leaf extract and the grape seed extract block melanogenesis from the source and resist ultraviolet damage by inhibiting tyrosinase activity and strongly resisting oxidation; the seville orange flower extract is used for soothing liver and regulating qi, and regulating internal pathogenesis; the almond extract and the donkey-hide gelatin powder have the effects of promoting blood circulation to remove blood stasis and nourishing yin and blood, improve microcirculation and nourish skin; vitamin C and vitamin E form an anti-oxidation cycle, so that melanin intermediates are directly reduced, and cell membranes are protected. All the raw materials supplement each other to jointly achieve the comprehensive effects of fading stains, brightening the skin color and improving the skin quality.

The invention belongs to the technical field of high polymer materials, and particularly relates to a polyolefin compound containing vitamin E and attapulgite at the same time. The compound disclosed by the invention comprises a polyolefin matrix, and vitamin E and attapulgite are added at the same time, and the compound comprises the following components in parts by mass: 100 parts of polyolefin; 0.03 to 2.0 parts of vitamin E; and 0.02 to 3.0 parts of attapulgite. In addition to the vitamin E and the attapulgite, the compound can also contain other auxiliaries or modifiers. The polyolefin compound has excellent thermal oxidation stability.

The invention relates to the technical field of frying oil treatment, in particular to a frying oil purification method which comprises the following steps: preparing an antioxidant part; wherein the anti-oxidation piece is composed of stainless steel, a microporous silicon dioxide layer, vitamin E and a slow-release film; putting the antioxidant part into the frying oil in advance to start frying operation, after the frying operation is finished, taking out the antioxidant part, carrying out separation treatment, and removing food residues to obtain roughly filtered oil; and adding the modified adsorbent into the coarsely filtered oil, heating and stirring for adsorption and purification, taking out after adsorption and purification are finished, and filtering. Wherein the modified adsorbent is prepared from activated clay and magnesium silicate. The modified adsorbent is prepared from the activated clay, the sodium silicate and the magnesium sulfate, so that the activated clay and the magnesium silicate are compounded; wherein the activated clay is high in deacidification and decolorization capacity, the magnesium silicate is selective in depolarity and low in oil loss, and the activated clay and the magnesium silicate are compounded to complement each other in advantages, so that efficient purification of the frying oil is realized.

The present invention relates to a solid composition comprising a lipophilic drug (such as a cannabinoid or Vitamin E) and a cyclodextrin wherein the lipophilic drug and the cyclodextrin are in the form of a combined complexation, and the lipophilic drug and the cyclodextrin in the combined complexation are either at a molar ratio of about 1:2; and methods of obtaining the same.

The invention belongs to the technical field of high-calcium dairy products, and particularly relates to low-sodium high-calcium long-term stable vitamin-containing cheese. The vitamin A and the vitamin D are added into the casein milk, calcium absorption and utilization are promoted, inorganic calcium salt does not need to be additionally added, the content of primary milk calcium is increased through a concentration technology, the high-calcium and low-sodium standard is achieved, and therefore the absorption advantage of the primary milk calcium is brought into play. Through improvement and deep coupling of three aspects of processes of secondary differential homogenization, steam direct injection instantaneous sterilization and reduced pressure flash evaporation, the shelf life, the stability and the flavor coordination of the plateau raw milk calcium cheese are obviously prolonged unexpectedly, and the product is good in fluidity and suitable for being sucked.

The disclosure relates to an oral composition comprising an active ingredient consisting essentially of alpha tocotrienol, gamma tocotrienol, delta tocotrienol, alpha tocopherol and phospholipid in specific percentages for use in liver health optimization. The compositions are stable at room temperature & accelerated storage conditions.

The invention discloses a preparation method of a vitamin C steady-state plant-based lactobacillus beverage, and belongs to the technical field of functional foods and beverages. Aiming at the technical problem that vitamin C in a plant-based beverage is extremely unstable in an acidic environment containing polyphenol and metal ions, an ascorbic acid derivative with a specific structure is innovatively adopted as a vitamin C source, and the derivative is ascorbic acid-2-O-phosphoramido amino acid choline salt; the preparation method comprises the steps of plant raw material treatment, enzymolysis, blending, homogenizing and degassing, ultrahigh-temperature instantaneous sterilization, fermentation, filling and the like. After the product is stored in a dark place at 25 DEG C for 12 months, the retention rate of vitamin C is greater than or equal to 90%, the viable count of lactic acid bacteria is greater than or equal to 1 * 10 < 7 > CFU / mL, and the long-term technical problem of bistabilization of vitamin C and probiotics in the plant-based lactic acid bacteria beverage is solved.

The invention provides a pharmaceutical composition for improving bone mineral density and a preparation method thereof, and belongs to the technical field of biological medicine, the pharmaceutical composition comprises lactarius vomica extract peptide, winged yam rhizome peel extract, rainbow trout extract, calcium citrate-glycine chelate, vitamin K2 and vitamin D3. The lactarius volemus extract peptide is obtained by sequentially carrying out enzymolysis on lactarius volemus by bromelain and subtilisin and purifying and extracting enzymatic hydrolysate through an LH-60 sephadex column. The winged yam rhizome peel extract is obtained by extracting the peels of winged yam rhizome tubers with an ethanol water solution and purifying and extracting the extracting solution with an AB-8 macroporous adsorption resin column. The rainbow trout extract is a product below 5kDa obtained by sequentially performing enzymolysis on fish heads, fish skins and fish scales of rainbow trout through trypsin and lumbrukinase. All the components are compounded according to a specific proportion, and the core effect of improving the bone mineral density is achieved through two-way regulation and control of bone metabolism, optimization of calcium utilization and improvement of safety.

The application discloses a multi-effect repairing and anti-allergy toothpaste composition and a preparation method thereof. The toothpaste comprises the following raw material components in percentage by mass: hydroxyapatite 1.0-10.0%, zeolite 0.02-0.8%, vitamin E 0.02-0.5%, lactoferrin 0.0005-0.02%, and the rest is base. When harmful bacteria form a biofilm in the oral cavity, the zeolite can destroy the biofilm formed by the harmful bacteria, so that the vitamin E and the lactoferrin enter the biofilm. The lactoferrin adsorbs iron ions near the harmful bacteria, so that the harmful bacteria cannot form a biofilm again. After rinsing, a large amount of water can take away the harmful bacteria, and finally the hydroxyapatite repairs. The effective synergistic closed loop of the hydroxyapatite, the zeolite, the vitamin E and the lactoferrin reconstructs a healthy oral micro-ecology from the source.

Provided herein are formulations to promote optimized workouts and enhance exercise results. The formulations provided herein can be in the form of a gummy and optionally can include stimulants, flavoring agents, bitter blocking agents, vitamins, and additional ingredients. Methods of making these formations are also provided herein. The formulations can be administered before a workout to enhance exercise performance.

The present invention relates to an aptamer set forth in SEQ ID NO: 1, and a composition for improving cognitive function and anti-aging comprising vitamin C the aptamer as active ingredients, wherein the aptamer of the present invention has a superior oxidative delay effect on vitamin C compared to other known aptamers, and the aptamer and / or vitamin C complex has improved cognitive function and anti-aging effects in aging animal models, and thus may be used in pharmaceutical, food, and / or cosmetic fields.

The invention relates to the technical field of in-vitro detection, in particular to a sample pretreatment method and a method for detecting VK2 and VD in serum. According to the specific technical scheme, the method comprises the following steps: carrying out protein precipitation after carrying out enzymolysis on serum, taking supernate, mixing the supernate with activated magnetic beads, enabling the magnetic beads to adsorb a target object, finally eluting the magnetic beads adsorbed with the target object by using eluent, collecting the eluent, and detecting the eluent to obtain vitamin K2 (VK2) and 25-hydroxy vitamin D (VD) at the same time. The problems that pretreatment operation is tedious, health is harmed and flux is low are solved by adopting an automatic magnetic bead method; the problems that detection equipment is expensive and difficult to popularize are solved by adapting to a conventional mass spectrum platform; the technical path is not only suitable for detection of vitamin K2 and 25-hydroxyvitamin D, but also provides a solution normal form with popularization value for detection of trace micromolecular markers which are difficult to popularize due to complex pretreatment or high equipment threshold.

The invention provides a milk flavor essence and a preparation method thereof. The method comprises the following steps: preparing an activated bacterium solution from German-type lactobacillus bulgaricus subspecies; anhydrous cream and whey powder are prepared into a fermentation substrate; adding the activated bacterial liquid into the fermentation substrate, and performing sealed fermentation to obtain a fermentation product; and carrying out first sterilization treatment on the fermentation product, carrying out centrifugal separation, and taking supernate as the milk-flavored essence. Whey powder is added when a fermentation substrate is prepared, the whey powder is rich in whey protein, lactose, vitamins and mineral substances, and glycometabolism, protein metabolism and lipid metabolism pathways are activated in the fermentation process, so that a fermentation product not only can be rich in target milk flavor substances, but also can synergistically contain various flavor compounds such as esters, alcohols and aldehydes, and the richness of the flavor substances is improved; the anhydrous cream and the whey powder are prepared into the fermentation substrate, so that a comprehensive and balanced growth environment is provided for the German-type lactobacillus bulgaricus subspecies, and the fermentation efficiency is improved.

The invention belongs to the technical field of aquaculture, and particularly relates to a decapterus maruadsi breeding feed and application thereof in improving the quality of decapterus maruadsi fertilized eggs. The invention provides a decapterus maruadsi breeding feed. The feed comprises a first feed and a second feed which are mutually independent, the first feed comprises a basal feed, fish cream and a nutrition enhancer; the second feed comprises the first feed and oyster meat; the nutrition enhancer contains calcium pantothenate, vitamin B1, vitamin B2, vitamin B6, vitamin C and vitamin F. When the culture feed for the decapterus maruadsi is used for performing nutrient enrichment on parent fishes of the decapterus maruadsi, synchronous development of sexual glands of male and female parent fishes of the decapterus maruadsi can be promoted, the quality of fertilized eggs of the decapterus maruadsi is improved, the good egg rate of the fertilized eggs of the decapterus maruadsi reaches 88.50% and is 39.15% higher than that of a control group, and the fertilization rate of the fertilized eggs reaches 79.58% and is 19.46% higher than that of the control group.

The present disclosure relates to compositions, nutraceutical compositions, and dietary supplements that improve gut health, enhance energy, improve focus and energy, reduce cravings, improve stress management, improve overall health, promote healthy aging, replenish nutrients, support immune health, promote healthy skin, promote hair and nail growth, and enhance recovery after physical activity. The compositions comprise one or more of each of seaweeds, enzymes, and protein; two or more of each of adaptogens, botanicals, extracts, fibers, microalgae, micronutrients, minerals, vitamins, and whole fruit or vegetable powders; and three or more probiotics.

The invention discloses a pet hair beautifying food and a preparation method thereof. The pet hair beautifying food is prepared from the following raw materials in percentage by weight: 85.0%-88.0% of fresh chicken breast, 5.0%-6.0% of fresh chicken liver, 2.0%-3.0% of krill oil, 1.5%-2.5% of krill meal, 1.0%-2.0% of fish oil and an additive, the additive comprises 0.2% of sodium hyaluronate, 0.1% of natural vitamin E and 0.1% of vitamin B. The pet hair beautifying food is good in palatability and has a hair beautifying effect.

The invention provides a plant foliar organic fertilizer and a preparation and use method thereof, and relates to the technical field of crop planting. The organic fertilizer solves the problem that an existing foliar fertilizer is difficult to consider crop yield, quality and ecological safety at the same time. The nutrient base liquid contains pomelo kernel pulp, shrimp shell cold soaking liquid, wood root bark suspension liquid, a vitamin composition and a potassium element additive. The preparation method comprises the following steps: preparing the component solutions, mixing, adding the vitamin and potassium additive, stirring at 5-16 DEG C to obtain the nutrient base solution, and mixing with water. The application method comprises the following steps: adjusting the spraying amount according to seasons, wherein the basic amount is 150-200L / hectare; potassium additives are proportioned according to growth parts, and vitamins are added seasonally; the basic amount in spring is increased by 10% in summer and reduced by 10% in autumn, and the vitamin C is doubled; atomization spraying is carried out in the morning or at dusk, and high temperature, strong light and rain are avoided; spraying is performed once every 7-10 days, and 2-3 times is a cycle. Natural organic chromium is adopted, activity is kept through a low-temperature process, seasonal part differentiated matching is achieved, and environment friendliness and high efficiency are achieved.

An anti-tumor pharmaceutical composition based on immune checkpoint blocking and a use thereof. The anti-tumor pharmaceutical composition comprises: paroxetine hydrochloride and a T cell enhancer, the T cell enhancer being at least one of vitamin E and thymosin. By means of a series of in vivo and in vitro experiments, it was found for the first time that cannabidiol and paroxetine hydrochloride can effectively reduce the expression of PD-L1 on a tumor cell membrane, thereby blocking the PD-1 / PD-L1 signaling pathway and enhancing the effect of T cells in killing tumor cells. T cell enhancer added on this basis can further increase the number and activity of T cells and significantly enhance the killing ability of T cells after relief from immunosuppression, greatly improving the anti-tumor effect of a drug. The components cannabidiol, paroxetine hydrochloride, and vitamin E+thymosin of the pharmaceutical composition can have a synergistic effect to improve the anti-tumor effect.

The present invention discloses a heart-protective complex composition for improving the absorption rate of Coenzyme Q10 and a preparation method thereof, relating to the technical field of medicine and functional foods. The core active ingredients comprise Coenzyme Q10, Vitamin E, and black pepper extract within a specific mass ratio range. Pharmaceutically acceptable carriers and antioxidant synergists may also be combined to prepare various oral dosage forms. By constructing a ternary active component system with a specific ratio, the present invention achieves temporal synergy between absorption promotion and antioxidant regeneration in vivo, thereby solving the technical problems of low oral bioavailability and insufficient myocardial targeted accumulation of existing Coenzyme Q10 preparations. It significantly enhances the conversion efficiency of Coenzyme Q10 into the active form available to myocardial cells, and can be widely used in the preparation of drugs or functional foods for preventing or treating heart diseases.