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705 results about "Vitamine e" patented technology

Novel association of active ingredients, pharmaceutical and / or nutraceutical compositions containing it and their use in the prevention and repair of damage to the central and peripheral nervous system

PCT designated stage expiredWO2025146608A1Nervous disorderAntipyreticNervous systemNutrition
The present invention relates to a novel association or combination of active ingredients useful in the prevention and repair of neuronal damage, both centrally and peripherally. In greater detail, the present invention relates to an association or combination of i) an extract of Gastrodia elata and ii) at least one ingredient selected from the group comprising or, alternatively, consisting of citicoline, L-acetylcarnitine and, preferably, at least one vitamin of group D, and / or mixtures thereof, and / or at least one vitamin of group B, and / or mixtures thereof. Furthermore, the invention also relates to the pharmaceutical compositions and / or compositions for medical devices (Regulation (EU) 2017 / 745) and / or nutraceutical and / or food compositions comprising that association and to their use in therapy, in particular in the protection of the functionality of the nervous system and in the prevention and / or treatment of central and peripheral neuropathies.
Owner:FUTURA S R L SOVICO

Zhejiang camellia japonica clone tissue culture and rapid propagation method

The invention discloses a Zhejiang camellia japonica clone tissue culture and rapid propagation method. A Zhejiang camellia japonica clone tissue culture and rapid propagation technical system is established by taking a non-lignified tender stem as an explant, sterilizing and then performing primary induction, subculture multiplication, strong bud culture and rooting culture. The explants are soaked before primary inoculation, and vitamin C and polyvinylpyrrolidone with certain concentration are added into a primary induction culture medium, so that browning of the explants can be effectively inhibited; hormone regulation and control and nutrient addition are combined, so that the primary induction rate reaches up to 95.3%, the multiplication coefficient reaches about 6.8, the rooting rate reaches 83.5%, efficient and rapid propagation can be realized, and the method is not limited by factors such as seasons, climate and regions. The rapid propagation offspring obtained by the system can maintain all excellent characters of a stock plant, and the strong bud obtained in the process can be used as a scion for grafting propagation, so that a technical support is provided for protection, development and utilization of rare germplasm resources and excellent clone of the Zhejiang red camellia.
Owner:RES INST OF SUBTROPICAL FORESTRY CHINESE ACAD OF FORESTRY

Natural mixed feed additive and preparation method thereof

The invention relates to the technical field of feed formulas, and particularly discloses a natural mixed feed additive and a preparation method thereof. The natural mixed feed additive comprises the following raw materials in parts by mass: 4-7 parts of vitamin E, 5-15 parts of beta-carotene, 10-16 parts of soybean oil, 20-35 parts of deionized water, 5-8 parts of modified probiotic microcapsules and 1-5 parts of an emulsifier, wherein the modified probiotic microcapsules contain sodium alginate-pectin composite microencapsulated probiotics; the preparation method comprises the following steps: heating 10-16 parts of soybean oil to 35-45 DEG C, then adding 4-7 parts of vitamin E and 5-15 parts of beta-carotene, and stirring; adding 1-5 parts of an emulsifier into 20-35 parts of deionized water, heating to 45-55 DEG C, stirring, and then slowly adding into the mixed solution obtained in the step S1; 5-8 parts of modified probiotic microcapsules are added, and stirring is conducted for 8-12 min under the condition of 100-200 r / min. The natural mixed feed additive disclosed by the invention has the advantage that the defect that the feed additive still has defects in the aspect of reducing intestinal diseases of animals can be overcome.
Owner:SHANDONG NEW ELEMENT BIOTECHNOLOGY CO LTD

Fusion vitamin D hydroxylase and application thereof in preparation of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3

The invention belongs to the technical field of gene engineering, and particularly relates to fusion vitamin D hydroxylase and application thereof in preparation of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3. The fusion vitamin D hydroxylase comprises a Vdh-K1 heme structural domain of which the amino acid sequence is shown as SEQ ID NO.1, a CYP116B65 redox structural domain of which the amino acid sequence is shown as SEQ ID NO.3, and a linker for connecting the Vdh-K1 heme structural domain and the CYP116B65 redox structural domain. The fusion vitamin D hydroxylase is a self-sufficiency enzyme, and can realize stable catalytic conversion of vitamin D2 and vitamin D3 on the premise of not depending on an Fdx and Fdr assisted electron transfer system.
Owner:SICHUAN UNIV

Dietary nutrition balance collocation generation method and system based on individualized difference demands, electronic equipment and storage medium

The embodiment of the invention discloses a dietary nutrition balance matching generation method and system based on individualized difference requirements, electronic equipment and a storage medium, and relates to the technical field of clinical nutriology. Comprising the following steps: calculating the basal metabolic rate of a user by using a human basal metabolic rate formula according to the age, gender, weight and height of the user; calculating daily required total energy consumption of the user according to the basal metabolic rate and the daily activity state; preliminarily determining intake proportions of carbohydrates, proteins, fats, vitamins and minerals of the user according to national or international nutrition standards on the basis of daily required total energy consumption; the intake proportion is adjusted according to the health condition and the allergy history of the user, and the target intake proportion of carbohydrate, protein and fat is determined; and obtaining nutritional ingredient information of the food materials based on the target intake ratio, and generating an optimal dietary nutrition collocation combination by using a genetic algorithm. The method is suitable for hospital clinical nutrition departments and ward patient nutrition management scenes.
Owner:山西医科大学第二医院(山西医科大学第二临床医学院)

Application of pediococcus pentosaceus in preparation of products for improving pork quality and intestinal flora

PendingCN120188846ABacteriaAnimal feeding stuffBiotechnologyTibetan pig
The invention provides application of pediococcus pentosaceus in preparation of a product for improving pork quality and intestinal flora, and relates to the technical field of animal feeding. The pediococcus pentosaceus disclosed by the invention is pediococcus pentosaceus LL2018368, is separated from the digestive tract of a Diqing Tibetan pig and is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.18709. The pediococcus pentosaceus disclosed by the invention has the advantages that the pediococcus pentosaceus can be used for preparing the pediococcus pentosaceus; the pediococcus pentosaceus LL2018368 is added into drinking water of the Du-Si pigs, the influence of the pediococcus pentosaceus LL2018368 on archaea, meat quality, tissue fat-soluble vitamins and excrement metabolite composition in the excrement of the Du-Si pigs is studied, and the result shows that the pediococcus pentosaceus LL2018368 enables the species of the archaea in the excrement to tend to be consistent, so that the content of the archaea in the excrement of the Du-Si pigs in the excrement of the Du-Si pigs in the excrement of the Du-Si pigs is increased. The contents of vitamin A and all-trans-retinol in kidney tissues are increased, and the probiotic functions of amino acid and fat metabolism related bacteria and enzymes are improved.
Owner:YUNNAN ANIMAL SCI & VETERINARY INST

Microbial composite reagent and preparation method thereof, and method for removing perfluorooctanoic acid

A microbial composite reagent, a preparation method thereof, and a method for removing perfluorooctanoic acid are disclosed. The preparation method of the microbial composite reagent includes steps of: preparing a glucose-based carbonaceous material by pyrolyzing glucose at 400° C. to 1000° C. for at least 0.5 hours under a protective atmosphere; mixing perfluorooctanoic acid-contaminated soil with a basal medium, molasses, a vitamin B, and water, and subjecting the mixture to microbial acclimation under an anaerobic condition to obtain an acclimated microorganism solution; subjecting the glucose-based carbonaceous material to microbial loading by anaerobically mixing the glucose-based carbonaceous material with the acclimated microorganism solution, thereby obtaining the microbial composite reagent.
Owner:TSINGHUA UNIVERSITY

Whitening and repairing composition containing PDRN and polypeptide and application of whitening and repairing composition

The invention relates to a whitening and repairing composition containing PDRN and polypeptide and application of the whitening and repairing composition. The composition comprises sodium hyaluronate, PDRN, polypeptide, vitamin C and cane sugar. Sodium hyaluronate, nucleic acid and polypeptide are adopted, so that the activity of collagen in the skin is enhanced, the moisture of cuticle and the integrity of a fiber structure are kept, the content of melanin in the epidermis is reduced, the skin barrier is repaired, the skin blood circulation is improved, anti-oxidation and anti-inflammatory treatment is performed, the skin color is brightened, and chromatosis is relieved, and sodium hyaluronate, nucleic acid and polypeptide are matched with one another; meanwhile, the release rate of nutritional ingredients is slowed down after the composition is injected into the skin, the action time is prolonged, and a better anti-degradation effect is achieved.
Owner:SUZHOU BOCHUANG TONGKANG PHARM TECH CO LTD

Preparation method of Witzia coagulans IOB502 microbial inoculum and application of Witzia coagulans IOB502 microbial inoculum in recovery of intestinal motility

The invention provides a preparation method of a Witzia ciliaris IOB502 microbial inoculum and an application of the Witzia ciliaris IOB502 microbial inoculum in the aspect of recovering intestinal motility, the Witzia ciliaris IOB502 microbial inoculum is prepared by adopting a method of carrying out low-oxygen stress staged fermentation on chickpeas by adopting the Witzia ciliaris IOB502, and the generation of vitamins B1 and B2 can be promoted. The microbial inoculum does not affect physiological development of important organs such as liver, spleen and small intestine of mice, can improve defecation symptoms of the mice with constipation, increase defecation times and water content of excrement, improve intestinal movement of the mice with constipation, promote smooth passage of intestinal contents, effectively improve colon injury of the mice with constipation, and improve the constipation rate of the mice with constipation. Comprising mucous membrane layer thinning and mucus secretion reduction.
Owner:TIANJIN MEDICAL UNIVERSITY GENERAL HOSPITAL +1

Method for improving nutritional quality of germinated brown rice through ultrasonic-assisted salt induction

The invention aims to provide a method for improving nutritional quality of germinated brown rice through ultrasonic-assisted salt induction. Brown rice is a whole-grain product and is rich in nutritional ingredients such as starch, protein, dietary fibers, vitamins and mineral substances and active functional factors. The nutritional ingredients of the germinated brown rice change drastically, and the nutritional value of the brown rice is greatly improved. According to the method, brown rice is taken as a raw material, the brown rice is soaked in a CaCl2 salt solution under the assistance of ultrasound, the germination temperature and time are optimized, the concentration of the CaCl2 salt solution is taken as an influence factor, and the change rule of nutritional ingredients and functional factors of the brown rice in the germination process is researched. Results show that after ultrasonic-assisted salt induction treatment, the contents of vitamin B2 and vitamin B6 in the germinated brown rice are increased to 58.2 mu g / 100g and 0.438 mg / 100g, and the content of gamma-aminobutyric acid is increased to 42.6 mg / 100g (dry basis). The germination of the brown rice promotes the activation and release of hydrolases such as amylase, protease and phytase, and nutritional ingredients in the brown rice are migrated, degraded, accumulated and the like, so that the nutritional quality of the brown rice is remarkably improved.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Vitamin D3 inclusion compound as well as preparation and preparation method thereof

The invention discloses a vitamin D3 clathrate compound and a preparation method thereof, and further discloses a calcium carbonate D3 tablet containing the vitamin D3 clathrate compound and a preparation method of the calcium carbonate D3 tablet. The vitamin D3 inclusion compound disclosed by the invention comprises the following components in percentage by mass: 0.05-0.75% of vitamin D3; 80.00 to 99.5 percent of hydroxypropyl-beta-cyclodextrin, and the balance of water; 1.00% to 10.00% of an antioxidant; 0.00 to 5.00% of an anti-sticking agent; wherein the antioxidant is butylated hydroxytoluene (BHT), vitamin E and sodium ascorbate. The invention also provides a preparation method of the vitamin D3 clathrate compound. The preparation method comprises the following steps: dissolving the vitamin D3 and the antioxidant in ethanol; the preparation method comprises the following steps: dissolving hydroxypropyl-beta-cyclodextrin in purified water, and then adding an anti-sticking agent; mixing the two solutions; and drying by using a spray dryer to prepare the vitamin D3 inclusion compound. The vitamin D3 inclusion compound prepared by the invention is high in inclusion rate and yield and can be stably stored for a long time, and a preparation (such as a calcium carbonate D3 tablet) prepared from the inclusion compound meets medicinal requirements, and is good in long-term stability, high in uniformity, simple to prepare and relatively low in cost.
Owner:REGENEX PHARMA LTD

Flammulina velutipes culture method and culture material

The invention relates to the technical field of flammulina velutipes planting, in particular to a flammulina velutipes culture method and compost, which comprises the following steps: S1, preparing purple sweet potato water; the preparation method comprises the following steps: washing fresh purple sweet potatoes, mixing with water in proportion, boiling, cooling, filtering, and taking filtrate as purple sweet potato water for later use; s2, preparing a culture material; the raw materials comprise corncobs, rice bran, bran, cottonseed hulls, sugar beet pulp, soybean hulls, corn flour, brewer's grains, calcium carbonate and shellfish fossils. The preparation method comprises the following steps: weighing solid raw materials in proportion, stirring the raw materials in a stirrer for 10 minutes to obtain a mixture, uniformly mixing the mixture, adding the purple sweet potato water prepared in the step S1, fully stirring the mixture until the mixture is uniformly mixed, and controlling the water content of a final culture material to be 62-68% to obtain the culture medium. The purple sweet potato water is used for completely replacing tap water to serve as a culture material component, the purple sweet potato water is not only a solvent, but also a natural nutrient solution rich in anthocyanin, polysaccharide, vitamins and mineral substances, flammulina velutipes hyphae can absorb and convert the substances, and the anthocyanin content in sporocarp is remarkably increased.
Owner:ANHUI KANGHENG BIOTECHNOLOGY CO LTD

Functional eye-protecting soft sweets capable of resisting oxidation and reducing apoptosis of eye cells and preparation method of functional eye-protecting soft sweets

The invention discloses functional eye-protecting soft sweets capable of resisting oxidation and reducing apoptosis of eye cells and a preparation method. The functional eye-protecting soft sweets comprise the following components in percentage by weight: 2-10% of functional components and the balance of auxiliary materials, the functional components comprise at least one of blueberry anthocyanin, lutein ester, zeaxanthin, astaxanthin, lycopene and beta-carotene, as well as vitamin C and / or vitamin E. The functional soft sweets provided by the invention have the effects of removing DPPH free radicals and reducing eye apoptotic cells, and compared with soft sweets without vitamin C / vitamin E, the vitamin C / vitamin E added in the formula can reduce the attenuation degree of functional nutrients in the effective period.
Owner:BIOSTIME GUANGZHOU HEALTH PROD

A natural plant extract composition for preventing hair loss and strengthening hair, and its preparation method and application

The present invention discloses a natural plant extract composition for preventing hair loss and fixing hair. Through the reasonable proportion and synergistic effect of seven kinds of plant extracts, including Hypericum perforatum extract, Guaiacaceae extract, Mangostana mangosteen peel extract, mango leaf extract, Polygonum multiflorum extract, Platycladus orientalis leaf extract, and ginger extract, 5α-reductase and main microorganisms such as Malassezia furfur, Propionibacterium acnes and Staphylococcus aureus that cause seborrheic alopecia are effectively inhibited, thereby reducing the probability of seborrheic alopecia. The beneficial ingredients in the seven kinds of plant extracts have the effects of promoting blood circulation and regulating scalp oil secretion, can promote hair growth, and improve the scalp environment. In addition, mango leaf extract and Polygonum multiflorum extract are rich in vitamins and nutrients, can nourish hair, enhance the elasticity and gloss of hair, and reduce hair breakage and shedding. The present invention also discloses the preparation method and application of the above-mentioned natural plant extract composition for preventing hair loss and fixing hair.
Owner:广州市比柔生物科技有限公司

Livestock water heater with a controlled composition dispenser and related method

A portable submersible livestock water quality dispensing device and design for a livestock drinking station is provided. The portable submersible livestock water quality dispensing device has a heating element and a variable pressure pump with internal compartments or inserts for accommodating biocides, minerals, vitamins and medicaments and preferably a rotatable circulation device and method for their controlled release and dosing.
Owner:CHAMBERLAIN MATTHEW +2

Ascorbic acid-S-glutathione conjugate and derivative as well as preparation method and application of ascorbic acid-S-glutathione conjugate

The invention provides an ascorbic acid-S-glutathione conjugate, a derivative, a preparation method and application of the ascorbic acid-S-glutathione conjugate. The conjugate is obtained by activating ascorbic acid-6-hydroxyl by halogenation or sulfo group and then connecting the activated ascorbic acid-6-hydroxyl with sulfydryl of glutathione through thioether. The invention also discloses derivatives such as salts, esters, N-acylates, N-alkylates and the like of the compound. The stability of the series of compounds is greatly improved compared with that of vitamin C, and the whitening effect is obviously better than that of vitamin C and glutathione monomers. The invention also discloses a preparation method of the series of compounds and application of the series of compounds as antioxidants, whitening agents, nutritional supplements and the like in cosmetics, foods, feeds and medicines.
Owner:NANJING SHENG DE BAI TAI BIOLOGY SCI & TECH CO LTD

Vitamin D3 injection pharmaceutical composition and application thereof

The invention provides a vitamin D3 liquid composition, the vitamin D3 liquid composition comprises vitamin D3 and polyethylene glycol-15-hydroxystearate, the pH value of the vitamin D3 liquid composition is 7.1-7.6, and the vitamin D3 liquid composition does not contain ethanol, propylene glycol, polyethylene glycol, poloxamer or polyvinylpyrrolidone. The aqueous solution composition is stable and uniform, is more suitable for injection compared with an oil solution, and can be used for preventing and treating vitamin D deficiency.
Owner:ANHUI IPCKE PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO LTD

Method for determining squalene content in white spirit

The invention relates to the technical field of detection, and particularly provides a method for determining the content of squalene in baijiu, the method utilizes gas chromatography-triple quadrupole mass spectrometry to determine the content of squalene in baijiu with different flavors, and the content of squalene in baijiu with different flavors is determined by adding reagents such as vitamin C and vitamin E and adopting effective treatment measures such as parallel concentration in a sample pretreatment process. The method improves the detection result repeatability and the detection efficiency, reduces the detection limit, has the advantages of good repeatability, high sensitivity, high detection efficiency and small organic solvent dosage, and is beneficial to environmental protection and occupational health and safety.
Owner:JING BRAND

Instant sugar-free vitamin mineral composition and preparation method thereof

The invention relates to the technical field of functional food preparation, in particular to an instant sugar-free vitamin mineral composition and a preparation method thereof. The composition comprises vitamin microcapsule powder, vitamin mineral particles, maltodextrin and a food additive. The composition is prepared by a three-step method comprising the following steps: firstly, preparing fat-soluble vitamin, natural colloid, protein and the like into microcapsules; carrying out superfine grinding on water-soluble vitamins and mineral substances, granulating with maltodextrin and the like, and controlling the particle size of particles; and finally, mixing the components in proportion. Sugar-free wall materials such as natural vegetable gum, protein and fibers are adopted, traditional saccharides are not used, and the sugar-free wall materials have good instant solubility, dispersity and stability, can effectively cover bitter taste and metal taste of vitamins and mineral substances, are suitable for different people, especially people needing sugar control, and achieve comprehensive, stable and easy-to-absorb nutritional supplement.
Owner:NANTONG LICHENG BIOLOGICAL ENG CO LTD +1

Feed premix for improving chicken quality

The invention provides a feed premix for improving chicken quality. The fresh-keeping agent is prepared from the following components in percentage by weight: 5%-15% of a flavor enhancing component, 10%-25% of a tenderness improving component, 3%-10% of an antioxidant fresh-keeping component, 2%-3% of a function enhancing component and the balance of a carrier and a diluent, the function strengthening component is prepared from beta-alanine embedded citronella essential oil and konjac glucomannan zymolyte; the flavor enhancing component comprises a rosemary extract, a yeast culture and curcumin in a mass ratio of (2-4): (1-3): 1; the tenderness improving component comprises conjugated linoleic acid, L-carnitine modified by glutamine transaminase and betaine in a mass ratio of (3-5): (2-4): 1; the antioxidant fresh-keeping component is vitamin E and tea polyphenol in a mass ratio of (1-2): 1. Through multi-component synergism and functional targeting optimization, a three-dimensional quality improvement system with enhanced flavor, improved tenderness, oxidation resistance and fresh keeping is constructed, so that the chicken quality is comprehensively upgraded.
Owner:BAIHE (SHANGHAI) BIOTECHNOLOGY CO LTD

Hawk tea beverage and preparation method thereof

The invention relates to the field of tea beverages, in particular to a litsea coreana beverage and a preparation method thereof.The litsea coreana beverage is composed of litsea coreana soup, baking soda, vitamins and water, the sugar degree of the litsea coreana beverage is 0.04-0.17%, and the pH value of the litsea coreana beverage is 5.5-6.5. The problems that an existing hawk tea beverage lacks the characteristic flavor of hawk tea and contains many additives can be solved.
Owner:CHONGQING PINZHENG FOOD CO LTD

Methods of administering vitamin A and lactic acid to gilts

The present disclosure relates to the field of livestock farming, and specifically provides a feeding method for gilts in batch for promoting onset of puberty and alleviating estrus disorder of gilts, which is aiming at an industrial problem that a large number of gilts are culled due to delayed puberty onset or estrus disorder. The method includes: feeding, prior to onset of puberty for gilts with vitamin A combined with lactic acid; and performing, subsequent to the puberty onset of gilts, estrus synchronization treatment and insemination treatment on the gilts. By applying vitamin A combined with lactic acid, the present disclosure alleviates the delayed puberty onset or estrus disorder of the gilts, reduces the feeding duration and feeding cost of the gilts, facilitates synchronous estrus treatment of the gilts.
Owner:CHINA AGRI UNIV

A method for restoring egg production of parent pigeons after typhoon disaster in Hainan

The present invention belongs to the technical field of feed preparation, and specifically relates to a method for restoring the egg production of parent pigeons after a typhoon disaster in Hainan. The present invention prepares parent pigeon feed by mixing corn, quinoa, cricket powder, Scenedesmus, almonds, shell powder, salt, vitamin A and vitamin E, and adds a composite bacterial agent to the parent pigeon feed, which is beneficial to the remodeling of the intestinal microbial flora of the parent pigeons, maintaining their metabolism, and enhancing their immunity. Therefore, the above substances are fed to parent pigeons after the disaster, and Chinese medicine extracts are added to the drinking water of the parent pigeons after the disaster for feeding. The egg production of parent pigeons after the typhoon disaster can be significantly restored, the morbidity of parent pigeons after the disaster is reduced, and a scientific basis is provided for restoring the production performance of parent pigeons after the typhoon.
Owner:ANIMAL HUSBANDRY & VETERINARY RES INST OF HAINAN ACAD OF AGRI SCI

Vitamin D3 and 7-dehydrocholesterol eutectic and preparation method and application thereof

The invention relates to a vitamin D3 and 7-dehydrocholesterol eutectic as well as a preparation method and application thereof. The eutectic is prepared from the following raw materials: vitamin D3 and 7-dehydrocholesterol in a molar ratio of (1-1.2): (1-1.2). The yield of the obtained eutectic substance is high, the preparation method is easy to operate, high-toxicity raw materials and waste residues difficult to treat do not exist, and the vitamin D3 eutectic method is more environmentally friendly and high in eutectic efficiency.
Owner:INNOBIO CORP LTD

Culture medium for gamma delta T cells and culture method of gamma delta T cells

The invention provides a culture medium for gamma delta T cells and a culture method of the gamma delta T cells, and belongs to the technical field of cell culture. According to the culture medium of the gamma delta T cells, OpTmizer serves as a basic culture medium, and the OpTmizer culture medium further contains IL-2 with the concentration being 150-250 IU / mL, IL-6 with the concentration being 40-60 [mu] mol / L, vitamin C with the concentration being 40-60 [mu] mol / L, vitamin B3 with the concentration being 8-12 [mu] mol / L and coenzyme Q10 with the concentration being 3-7 [mu] mol / L. The prepared gamma delta T cell culture medium is used for culturing gamma delta T cells with improved killing activity, and the killing rate of the cultured gamma delta T cells on A549 cells and HepG2 cells can be remarkably improved.
Owner:广东壹加再生医学研究院有限公司

Nutrition enhancer beneficial to bone health of middle-aged and elderly people, preparation method of nutrition enhancer and application of nutrition enhancer in preparation of medial care food

The invention provides a nutrition enhancer beneficial to bone health of middle-aged and elderly people, a preparation method of the nutrition enhancer and application of the nutrition enhancer in preparation of medial care food, and belongs to the field of nutritious food. The nutrient supplement comprises a plant fermentation product, osteopontin peptide, collagen peptide, N-acetylglucosamine and calcium, vitamins and mineral substances can be added, and the plant fermentation product is obtained by performing anaerobic fermentation on rhizoma drynariae and chestnuts through a complex microbial inoculant composed of lactobacillus reuteri and bifidobacterium longum subsp. Longum; the collagen peptide is prepared by performing enzymolysis on bovine bones through alkaline protease and flavourzyme; the hydrogel is prepared by adopting a sodium alginate-calcium chloride-carboxymethyl chitosan micro-capsule embedding process. An in-vitro experiment shows that the nutrition enhancer can remarkably promote osteoblast proliferation, differentiation and mineralization; animal experiments show that the bone mineral density of osteoporosis model mice can be effectively improved. The nutrition enhancer disclosed by the invention is suitable for preparing care food and bone health products, and has a remarkable effect of improving bone health of middle-aged and elderly people.
Owner:HENAN UNIVERSITY OF TECHNOLOGY

High-stability vitamin D3 granules and preparation method thereof

The invention belongs to the technical field of medicines, and particularly relates to high-stability vitamin D3 granules and a preparation method thereof. The preparation method of the vitamin D3 granules provided by the invention comprises the following steps: (1) mixing vitamin D3 and an oil-phase solvent to obtain an oil phase; (2) mixing an emulsifier, a film-forming agent, a thickening agent and water to obtain a water phase; (3) mixing, shearing and homogenizing the oil phase and the water phase to obtain a vitamin D3 emulsion, and (4) performing spray drying to obtain vitamin D3 particles; the viscosity of the vitamin D3 emulsion ranges from 350 mPa.s to 400.9 mPa.s; in the spray drying, the feeding speed of the vitamin D3 emulsion is 160 to 180 mL / h; the preparation method is simple and convenient, low in cost and easy for industrial production; the prepared vitamin D3 particles are uniform in particle size, good in content uniformity and controllable in specification.
Owner:CHINA RESOURCES SANJIU MEDICAL & PHARMA CO LTD

Microcapsule, preparation method therefor, and use thereof in preventing and / or treating damage to salivary glands caused by radiation therapy

A microcapsule containing vitamin C and nitrate, said capsule comprising a wall material and a core material encapsulated in the wall material. The wall material comprises pectin and sodium carboxymethyl cellulose, and the core material comprises vitamin C, nitrate, and chitosan. The raw materials of the microcapsule comprise, in parts by weight: pectin 0.7-1.2 parts by weight, sodium carboxymethyl cellulose 0.7-1.2 parts by weight, chitosan 1 part by weight, and vitamin C and nitrate in a total amount of 0.3-1.2 parts by weight, the molar ratio of vitamin C to nitrate ions being 1:1-1:5. A use of the microcapsule in the preparation of a drug for preventing and / or treating damage to the salivary glands caused by radiation therapy, in particular a use in the preparation of a drug for preventing and / or treating damage to the salivary glands caused by radiation therapy for nasopharyngeal carcinoma.
Owner:CAPITAL UNIVERSITY OF MEDICAL SCIENCES +1

Nutritional composition for neurodegeneration and neurotrauma

PCT designated stage expiredWO2025003349A1Nervous disorderDispersion deliveryInjury brainNutrition
The invention relates to a nutritional composition comprising a combination of (i) omega-3 fatty acid DHA with (ii) vitamin B2 and (iii) vitamin D3 and one or more from (iv) choline or a salt thereof and / or choline esters; and (v) dietary fibres and / or dietary butyrate for use in the treatment of neurodegenerative diseases and / or neurotrauma, brain injury and / or brain damage. The invention also relates to a composition comprising a combination of DHA, vitamin B2, vitamin D3 with one or more from (iv) choline or a salt thereof and / or choline esters; and (v) dietary fibres and / or dietary butyrate.
Owner:NV NUTRICIA