78 results about "Vitamin d 3" patented technology

A method for administering an antioxidant composition to humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple antioxidant micronutrient composition comprising vitamin A (palmitate), beta carotene (from natural d. salina), vitamin C (calcium ascorbate), vitamin D-3 (cholecalciferol), natural source vitamin E including both d-alpha tocopheryl and d-alpha tocopheryl acid succinate, thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid (folacin), d-biotin, selenium (1-seleno methionine), chromium picolinate, zinc glycinate, calcium citrate, and magnesium citrate. For persons over the age of about 51, the composition preferably further comprises one or more of co-enzyme Q10, N-acetyl cysteine, and alpha lipoic acid. Preferably, also, vitamin D is added for women over the age of about 36.

Methods and pharmaceutical compositions for use in the treatment of a benign and / or a malignant proliferative pathologies are disclosed. The methods comprise administration of nicotinamide or its analogs and / or cADPR or its analogs, optionally in combination with a vitamin D3 analog or a Vitamin A analog.

The invention provides a feed additive for improving the quality of the fur of a furry animal. The additive is obtained by mixing a semi-finished vitamin product, a semi-finished trace element product, dihydropyridine, methionine, cystine and corn gluten meal according to a weight ratio of 1:1:0.3-1:0.2-0.9:0.1-0.6:2, wherein the semi-finished vitamin product is prepared by uniformly mixing the following components: 5-22 parts of vitamin A, 3-8 parts of vitamin D, 10-25 parts of vitamin E, 3-8 parts of vitamin B1, 8-15 parts of biotin, 1-3 parts of vitamin B6, and 120-160 parts of the corn gluten meal, and the semi-finished trace element product is prepared by uniformly mixing the following components: 10-20 parts of methionine chelated zinc, 2-5 parts of methionine chelated copper, and 70-90 parts of zeolite powder. The additive of the invention allows the quality of the fur of the furry animals (martens, foxes and raccoon dogs) to be substantially improved, the hair density to be increased, the hair length to be improved, the hide toughness to be increased and the culture benefit to be improved.

The invention provides 1,3 acylated, 24-keto vitamin D3 compounds of formula I: wherein: X1 and X1 are each independently H2 or ═CH2, provided X1 and X1 are not both ═CH2; R1 and R2 are each independently, hydroxyl, OC(O)C1-C4 alkyl, OC(O)hydroxyalkyl, OC(O)haloalkyl, provided that R1 and R2 are not both hydroxyl; R3 and R4 are each independently hydrogen, C1-C4 alkyl, hydroxyalkyl, or haloalkyl, or R3 and R4 taken together with C20 form C3-C6 cylcoalkyl; and R5 and R6 are each independently C1-C4 alkyl, hydroxyalkyl, or haloalkyl; and pharmaceutically acceptable esters, salts, and prodrugs thereof. Methods for using the compounds to treat vitamin D3 associated states, and phar,aceutical compositions containing the compounds are also disclosed.

The invention discloses honeysuckle rooting liquid. Each liter of solution comprises the following ingredients in parts by weight: 3 to 6 parts of ABT rooting powder, 20 to 30 parts of heteroauxin, 20 to 30 parts of naphthylacetic acid, 2 to 3 parts of potassium nitrate, 1 to 2 parts of copper sulfate, 2 to 4 parts of zinc sulfate, 5 to 10 parts of polyving akohol, 10 to 20 parts of ammonium nitrate, 3 to 5 parts of vitamin D, 5 to 8 parts of 4-iodiphenoxyaceticacid, 20 to 30 parts of 6-benzylaminopurine and 20 to 30 parts of gibberellin. The honeysuckle rooting liquid has the advantages that the cutting seedling rooting of honeysuckles can be promoted, the rooting time is shortened, the rooting rate is improved, the honeysuckle rooting liquid also contain trace elements, the vegetative growth can be accelerated, deep roots and luxuriant leaves are realized, and crop individuals develop strongly, so the survival rate of the cutting seedlings of the honeysuckles can be improved.

The present invention relates to methods of co-administration of various vitamin and mineral compositions, and in a specific embodiment, said methods comprise co-administering one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states; and kits provided for co-administration of various vitamin and mineral compositions, and in a specific embodiment, said kits comprise one composition comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and a second composition comprising omega-3 fatty acids such as DHA, to supplement the nutritional needs of individuals within physiologically stressful states.

The invention provides Gemini vitamin D3 compounds, methods for using the compounds to treat vitamin D3 associated states and pharmaceutical compositions containing the compounds.

Oral and topical pharmaceutical compositions, kits and methods of treatment thereof for treating various skin disorder including acne, psoriasis, ichthyosis, photoaging, photodamaged skin, and, skin cancer. Exemplary vitamin D analogs as active pharmaceutical ingredients include 2-methylene-19-nor-20(S)-1α-hydroxy-bishomopregnacalciferol, 19-nor-26,27-dimethylene-20(S)-2-methylene-1α,25-dihydroxyvitamin D3, 2-methylene-1α,25-dihydroxy-(17E)-17(20)-dehydro-19-nor-vitamin D3, 2-methylene-19-nor-(24R)-1α,25-dihydroxyvitamin D2, 2-methylene-(20R,25S)-19,26-dinor-1α,25-dihydroxyvitamin D3, 2-methylene-19-nor-1α-hydroxy-pregnacalciferol, 1α-hydroxy-2-methylene-19-nor-homopregnacalciferol, (20R)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol, 2-methylene-19-nor-(20S)-1α-hydroxy-trishomopregnacalciferol, 2-methylene-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnacalciferol, 2-methylene-(20S)-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnancalciferol, (2-(3′hydroxypropyl-1′,2′-idene)-19,23,24-trinor-(20S)-1α-hydroxyvitamin D3, 2-methylene-18,19-dinor-(20S)-1α,25-dihydroxyvitamin D3, a stereoisomer thereof, a prodrug thereof in oral compositions, a salt thereof, and / or a solute thereof. Compounds that activate retinoic acid receptors, such as retinoyls and retinoyl esters, include 13-cis-retinoic acid, all-trans-retinoic acid, (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexeneyl)nona-2,4,6,8-tetraenoic acid, 9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid, 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-napthoic acid, 4-[1-(3,5,5,8,8-pentamethyl-tetralin-2-yl)ethenyl]benzoic acid, retinobenzoic acid, ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]pyridine-3-carboxylate, retinoyl t-butyrate, retinoyl pinacol, retinoyl cholesterol, an isomer thereof, a prodrug thereof for oral compositions, an ester thereof, a salt thereof, and / or, a solute thereof. Combinations of such active ingredients demonstrate synergistic efficacy.

The invention discloses a halotolerant bacteria culture medium nutrient, a preparation method, a domestication method and an application thereof. The halotolerant bacteria culture medium nutrient contains the following components in parts by weight: water, sodium alginate, kelp powder, fish meal, bean pulp, expanded bean flour, yeast, gulfweed, spirulina, vitamin C, choline chloride, nicotinic acid, calcium pantothenate, 3 parts of vitamin D, vitamin E, inositol, vitamin A, vitamin H2, vitamin B1, vitamin B2, vitamin B12, vitamin K3, bone protein powder, calcium hydrophosphate, flour, dry seamud and mineral substance microelement metal salt compound. The halotolerant bacteria culture medium nutrient can be used for domesticating various halotolerant bacteria, so that the treatment requirement of high salinity wastewater complex environment can be met and a better purifying effect and higher stability can be achieved.

The invention discloses an leucine-containing infant drinking water, characterized by that, each liter of RO pure water contains leucine 15-16mg, vitamin D 3-5ug, vitamin A 100-200ug, íóvitamin B1 30-50ug, vitamin B2 20-40ug, nicotinic acid 1-2mg, and glucose 100-250g. The leucine-containing nutritious drinking water according to the invention can be supplied to infants for direct drinking or as modulation food.

The present invention relates to a calcium carbonate vitamin D3 composition and water-free-swallowing granules thereof, and belongs to the field of pharmaceutical preparations. According to the present invention, in the calcium carbonate vitamin D3 composition and the calcium carbonate vitamin D3 water-free-swallowing granules containing the composition or prepared from the composition, vitamin D3is fed in a vitamin D3 carrier manner; compared to the granules in the prior art, the granules of the present invention have the following advantages that the rapid water-free swallowing of the granules in the oral cavity cam be achieved, the taste is good, and the compliance of the user can be improved, such that the problems of poor content uniformity and poor stability of vitamin D3 in the preparation can be solved; and particularly compared to the existing calcium carbonate vitamin D3 preparation, the preparation of the present invention has the following advantages that the calcium carbonate content in the unit preparation is increased while the loading is lower than the loading of the traditional dosage form.

The invention relates to a multi-vitamin gunk for poultry and a preparation method thereof and in particular to a multi-vitamin gunk suitable for pigs and production process thereof. Each kilogram gunk contains vitamin A >=32000000 IU, vitamin D3>=10000000 IU, vitamin E>=90 g, vitamin K3>=10 g, vitamin B1>=10 g, vitamin B2>=25 g, vitamin B6>=10 g, vitamin B12 >=75 mg, biotin>=600 mg, folic acid>=5 g, nicotinamide>=100 g, pantothenic acid>=50 g, antioxidant>=5 g, ethoxyquin>=0.75 g, and the rest is rice chaff. The multi-vitamin gunk for poultry lowers feed meet ratio of pigs and improves growing performance and immunity performance. For breeding pigs, the multi-vitamin gunk for poultry can improve breed performance of the pigs, weaning weight and immunity of piglets and survival rate of the piglets.

Uses of a vitamin D compound in the preparation of drugs for preventing or treating cystitis, urethritis and / or urinary tract infection, as well as a pharmaceutical composition, a pharmaceutical preparation and a kit that comprise the vitamin D compound, the vitamin D compound comprising a vitamin D2, a vitamin D3, an active form of the vitamin D3 or a similar substance, and the active form of the vitamin D3 being 25-hydroxyvitamin D3 or 1,25-dihydroxyvitamin D3.

The invention relates to complex vitamin premix for poultry and a preparation method therefore, in particular to a premix additive of feeds. The complex vitamin premix comprises the following components of: not less than 32,000,000 IU of vitamin A, not less than 10,000,000 IU of vitamin D3, not less than 120g of vitamin E, not less than 10g of vitamin K3, not less than 10g of vitamin B1, not lessthan 30g of vitamin B2, not less than 15g of vitamin B6, not less than 100mg of vitamin B12, not less than 500g of biotin, not less than 5g of folic acid, not less than 200g of nicotinic acid, not less than 60g of pantothenic acid, not less than 0.75g of ethoxy quinoline and not more than 274.95g of rice chaff. The complex vitamin premix for poultry has the functions of improving the growth speedand the immunization performance of the poultry, improving the propagation performance of breeding poultry, increasing the survival rate of chicken and reducing the death rate of the poultry in laying period.

Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1α(OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3-β-hydroxyl group of 1α(OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds.

A blueberry protein nutrition powder consists of the following materials in parts by weight: 30 equal parts of blueberry powder, 40 equal parts of soy protein isolate powder, 15 equal parts of skimmedmilk powder, 3 equal parts of vitamin D3, 2 equal parts of tricalcium phosphate, 4 equal parts of fructose and 6 equal parts of maltodextrin. A preparation method of the blueberry protein nutrition powder adopts altogether four steps to prepare a finished product of the blueberry protein nutrition powder. The method adopts the blueberry powder and the soy protein isolate powder as main raw materials, and is scientific in compatibility and simple and reasonable in preparation process. The prepared nutrition powder effectively reserves the color, flavor and nutrient components of the raw materials, and has little nutrient loss. The method enables blueberry foods to be more diversified, and overcomes the defects that fresh blueberry fruits are not easy to store and are not convenient for people to eat in any season and at any time. Based on the above advantages, the nutrition powder has a good prospect.

The invention discloses a nutritional supplement food formula for pregnant women and wet nurses. The nutritional supplement food formula comprises the following components by mass: 10-25g of alpha-whey protein, 6-15 [mu]g of nucleotide, 4-13 [mu]g of xanthophyll, 5-10g of lactose, 400-700 [mu]g of vitamin A, 1.3-4.8 [mu]g of vitamin B, 60-230 mg of vitamin C, 3-10 [mu]g of vitamin D, 140-400 [mu]gof folic acid, 5-14 mg of vitamin E, 26-80 mg of vitamin K, 2.8-12 mg of pantothenic acid and 200-840 mg of choline. The nutrients of the nutritional supplement food formula for pregnant women and wet nurses can meet nutrient requirements for bodies and foetuses, can promote proper development of the foetuses, can prevent and reduce complication during a pregnancy period, can solve the problems of low birth weight infants and the like, and can achieve a certain effect on improvement on nutrients of the pregnant women and wet nurses.

Methods of increasing the thickness of the epidermal layer in the skin of a human comprising topically administering a therapeutically effective dose of an active pharmaceutical ingredient comprising a vitamin D analog including 2-methylene-19-nor-20(S)-1α-hydroxy-bishomopregnacalciferol, 19-nor-26,27-dimethylene-20(S)-2-methylene-1α,25-dihydroxyvitamin D3, 2-methylene-19-nor-(24R)-1α,25-dihydroxyvitamin D2, 2-methylene-1α,25-dihydroxy-(17E)-17(20)-dehydro-19-nor-vitamin D3, 2-methylene-(20R,25S)-19,26-dinor-1α,25-dihydroxyvitamin D3, 2-methylene-18,19-dinor-(20S)-1α,25-dihydroxyvitamin D3, 2-methylene-19-nor-1α-hydroxy-pregnacalciferol, 1α-hydroxy-2-methylene-19-nor-homopregnacalciferol, (20R)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol, 2-methylene-(20S)-19-nor-1α-hydroxy-trishomopregnacalciferol, 2-methylene-(20R)-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnacalciferol, 2-methylene-(20S)-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnacalciferol, 2-(3′hydroxypropyl-1′,2′-idene)-19,23,24-trinor-(20S)-1α-hydroxyvitamin D3, or 13,13-dimethyl-des-C,D analog of (20S)-2-methylene-1α,25-dihydroxy-19-nor-vitamin D3, and pharmaceutical topical formulations and topical dosage forms thereof using a pharmaceutically suitable carrier vehicle.

The invention provides vitamin D3 analogs of cholecalciferol, substituted at carbons-26 and 27 with deuterated alkyl groups, e.g., trideuteromethyl, wherein carbon-16 is a single or double bond, and carbon-23 is a single, double, or triple bond. The invention provides pharmaceutically acceptable esters, salts, and prodrugs thereof. Methods for using the compounds to treat vitamin D3 associated states, and pharmaceutical compositions containing the compounds are also disclosed.

The invention relates to the field of cosmetics, and especially relates to a moistening oil-controlling face washing lotion containing aster tataricus extractive and a preparation method thereof. The moistening oil-controlling face washing lotion containing aster tataricus extractive is prepared from the following raw materials in parts by weight: 10-15 parts of aster tataricus extractive, 10-15 parts of a natural extractive, 5-10 parts of aloe gel juice, 20-35 parts of deionized water, 10-20 parts of nanometer bamboo charcoal powder, 2-6 parts of alkyl polyglucoside, 3-5 parts of hydrolyzed collagen, 3-5 parts of hydrolyzed vegetable protein, 5-8 parts of sodium alginate, 3-5 parts of vitamin B2, 3-5 parts of vitamin D3, 3-5 parts of vitamin C, and 2-5 parts of natural essence. The provided face washing lotion has the various physical and chemical indexes reaching or exceeding national standards, the production technology of the provided face washing lotion is same to that of a conventional face washing lotion, the face washing lotion employs fully natural compositions, has the sensory indexes and the physical and chemical indexes all according with prescribed requirements, and is good in usage effect and free of adverse influence on human body.

The invention belongs to the technical field of health-care food, and provides a calcium and vitamin soft capsule. The calcium and vitamin soft capsule comprises capsule skin and a content substance; the content substance comprises, by weight, 20 to 25 parts of an edible calcium agent, 30 to 40 parts of corn oil, 3 to 7 parts of vitamin D, 2 to 5 parts of vitamin K2, 5 to 10 parts of water soluble pearl powder, 3 to 5 parts of beeswax, and 3 to 6 parts of an antioxidant; and the capsule skin comprises, by weight, 5 to 15 parts of gelatin, and 10 to 15 parts of glycerin. The calcium and vitamin soft capsule is capable of providing human with abundant calcium and vitamins; the composition is scientific and reasonable; interaction of vitamin K2, vitamin D, and calcium is achieved, health care effect is improved greatly; vitamin D and vitamin K2 are capable of promoting calcium absorption and mineralization deposition on skeleton effectively, and possess excellent effect on prevention of diseases such as osteoporosis and atherosclerosis; water soluble pearl powder is capable of inhibiting generation of melanin, and whitening skin; synergistic effects of the ingredients are achieved; and no side effect is caused.

The invention provides a feed additive with a mould-proof, anti-oxidization and detoxifying function. The feed additive comprises the following ingredients in parts by weight: 4 to 7 parts of glucose oxidase, 4 to 7 parts of edible tannin, 4 to 7 parts of glucuronic acid lactone, 2 to 5 parts of tert-butylhydroquinone, 5 to 8 parts of beta-carotene, 3 to 5 parts of methionine, 3 to 5 parts of vitamin E, 3 to 5 parts of vitamin D, 3 to 5 parts of vitamin A, 3 to 5 parts of selenium and 40 to 50 parts of sepiolite clay. The feed additive is added to the feed, so that not only can mildew and oxidization of the feed be prevented, but also the feed which is slightly mildewed can be continuously fed because the feed additive has a function of eliminating the mycotoxin of a body, and the waste of the feed can be reduced.

A radioactive protection micronutrient formulation system is provided and the system comprises: a formulation consisting essentially of antioxidants, the antioxidants are selected from the group consisting essentially of vitamin C, vitamin E, N-acetyl cysteine, natural mixed carotenoids, and alpha-lipoic acid, vitamin A (palmitate), vitamin D-3 (cholecalciferol), thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid, D-Biotin, selenium (1-seleno-methionine), chromium picolinate, zinc glycinate, calcium citrate and magnesium citrate and mixtures thereof; and plus a booster formulation selected from a group consisting essentially of vitamin C, d-alpha tocopheryl acid succinate, alpha tocopherol, N-acetyl cysteine, natural mixed carotenoids and alpha lipoic acid, the formulation is designed to reduce the risk in humans exposed to doses of ionizing radiation of becoming subjected to at least one condition selected from the group consisting essentially of radiation-induced acute leukemia, breast cancer, thyroid cancer and other somatic and heritable mutations.

The invention is suitable for the technical field of feeds, and provides a feed for improving the propagation properties of breeding white-feather male broilers. The feed consists of the following raw materials in percentage by mass: 65-70% of corn, 9-11% of soybean meal, 14-18% of wheat bran, 0-2% of soybean oil, and 5% of a premix feed, and after the raw materials are mixed, 200-300mg of zinc fumarate is added to every kilogram of the feed, wherein every kilogram of the premix feed comprises 180000-200000IU of vitamin A, 80000-100000IU of vitamin D3, 4000-6000IU of vitamin E, 100-150mg of vitamin K3, 100-150mg of vitamin B1, 500-700mg of vitamin B2, 150-200mg of vitamin B6, 1-2.0mg of vitamin B12, 1000-1500mg of nicotinamide, 350-500mg of pantothenic acid, 50-150mg of folic acid, 5-10mg of biotin, 10000-15000mg of choline, 10-20% of calcium element, 4-6% of phosphorus element, 2500-3000mg of manganese element, 20-40mg of iodine element and 8-10mg of selenium element. The feed disclosed by the invention can improve the quality of the semen of the breeding male broilers, and finally the purpose of improving the propagation properties of the breeding white-feather male broilers is reached.