33 results about "Thiamine mononitrate" patented technology

A method for optimizing the health of humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple antioxidant micronutrient composition comprising vitamin A (palmitate), beta-carotene (from natural d. salina), vitamin C (calcium ascorbate), vitamin D-3 (cholecalciferol), natural source vitamin E including both d-alpha tocopherol and d-alpha tocopheryl acid succinate, thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid (folacin), d-biotin, selenium (l-seleno methionine), chromium picolinate, zinc glycinate, calcium citrate, and magnesium citrate. For persons over the age of about 51, the composition preferably further comprises one or more of co-enzyme Q10, N-acetyl cysteine, and alpha lipoic acid. Preferably, also, vitamin D is added for women over the age of about 36.

The invention discloses an 8-amino acid / 11-vitamin containing micro granule capsule and a preparation method thereof, wherein the micro granule capsule contains 7 ball micro granules consisting of the following raw materials in part by weight: 2.66-9.9 parts of thiamine mononitrate micro granule, 16.35-20.5 parts of vitamin micro granule a, 35.0-44.1 parts of amino acid micro granule a, 11.4-14.4parts of vitamin micro granule b, 6.65-10.5 parts of amino acid micro granule b, 12.73-16.0 parts of vitamin C micro granule and 5.7-9.36 parts of vitamin AD micro bead. The method has the advantages of scientific and reasonable proportion, good stability of products, no toxicity and side effect and excellent biological effect, and can be used for the preparation of medicines treating chronic liver and kidney diseases and of food alleviating and eliminating physical fatigue caused by sports training.

The invention discloses a fermented-type dairy product which includes an exercise functional element comprising: vitamin D3, vitamin E acetate, thiamine mononitrate, pyridoxine hydrochloride, nicotinamide, an iron agent, a zinc agent and taurine. The invention also provides two preparation methods of two different fermented-type dairy products, wherein the preparation methods can be respectively used for preparing a milk beverage and yogurt containing the exercise functional element. When the dairy product is prepared, the exercise functional element, a metal chelating agent and a stabilizing agent are added to the dairy product at a certain ratio, so that the dairy product is reduced in fermentation time and fermentation risk, is improved in production efficiency, is reduced in production cost and is relatively increased in nutritional value. In addition, a large amount of nutrients in fermented milk can be digested and absorbed more easily after exercises, and the fermented-type dairy product is ensured in stability during selling and storing.

The invention discloses a water-soluble vitamin freeze-dried preparation for injection. 1000 bottles of freeze-dried preparations are prepared from the following raw materials: 2.8-3.4g of thiamine mononitrate, 36-44g of nicotinamide, 4.4-5.4g of pyridoxine hydrochloride, 14.8-18.1g of sodium pantothenate compound, 4.4-5.4g of riboflavin sodium phosphate, 102-124g of sodium ascorbate, 54-66mg of biotin, 0.36-0.44g of folic acid, 4.5-6.0mg of vitamin B12, 0.4-0.6g of methyl p-hydroxybenzoate, 280-320g of glycine, 0.4-0.6g of ethylene diamine tetraacetic acid disodium salt and 2000-3000ml of water for injection. The stability of existing sodium pantothenate is obviously improved by the obtained sodium pantothenate compound, thus ensuring that the sodium pantothenate containing water-soluble vitamin freeze-dried preparation for injection has ideal stability and curative effect and further ensuring medication safety of the patients.

The invention discloses a method for preparing a thiamine hydrochloride crystal product. Thiamine mononitrate is dispersed into a solvent, and thiamine mononitrate turbid liquid with the concentration of 0.05 g / ml to 0.2 g / ml is obtained, and heated to 50 DEG C to 70 DEG. Chlorosulfonic acid is dropwise added to concentrated hydrochloric acid to generate hydrogen chloride gas, and the gas is introduced into to concentrated sulfuric acid to be dried, and is introduced into the thiamine mononitrate turbid liquid under stirring action. After introduction of the hydrogen chloride gas is completed, heat preservation is carried out for 15 min to 30 min, then the temperature is reduced to 10 DEG C, the cooling rate ranges from 0.1 DEG C / min to 0.5 DEG C / min, filtering, washing and drying are carried out, and then thiamine hydrochloride crystals are prepared. The crystals are rhabdolith, the angle of repose ranges from 31 DEG C to 36.4 DEG C, and the bulk density ranges from 0.50 g / ml to 0.608 g / ml. The thiamine hydrochloride crystal product is good in liquidity. According to the method, the process that thiamine hydrochloride methyl alcohol solvent compounds are formed firstly, then drying is carried out to remove methyl alcohol is avoided, and therefore environmental pollution is reduced, and cost and solvent residues are reduced. The method can be suitable for large-scale production.

The invention relates to a compound amino acid capsule (8-11) and a preparation method thereof, specifically to a capsule including pellets of eight amino acids and eleven vitamins and a preparation method thereof. The capsule comprises 7 spherical pellets which are composed of the following raw materials by weight: 2.66 to 9.9 parts of a thiamine mononitrate pellet, 16.35 to 20.5 parts of a vitamin pellet a, 35.0 to 44.1 parts of an amino acid pellet a, 11.4 to 14.4 parts of a vitamin pellet b, 6.65 to 10.5 parts of an amino acid pellet b, 12. 73 to 16.0 parts of a vitamin C pellet and 5.7 to 9.36 parts of a vitamin AD bead. The capsule provided by the invention has the advantages of a scientific and reasonable ratio, good stability, no toxic and side effects, high security and good biological effects and can be applied in preparation of medicines used for treating chronic liver and kidney diseases and of foodstuffs used for alleviating and eliminating physical fatigue caused by exercise training. The capsule provided by the invention has characteristics superior to those of the prior art.

The invention discloses a water-soluble vitamin composition freeze-drying preparation for injection. The freeze-drying preparation comprises the following raw materials and is prepared into 1,000 bottles: 2.8 to 3.4 grams of thiamine mononitrate, 36 to 44 grams of nicotinamide, 4.4 to 5.4 grams of pyridoxine hydrochloride, 14.8 to 18.1 grams of sodium pantothenate, 4.4 to 5.4 grams of riboflavin sodium phosphate, 102 to 124 grams of sodium vitamin C, 54 to 66 milligrams of biotin, 0.36 to 0.44 gram of folic acid, 124.5 to 6.0 milligrams of vitamin B, and 0.4 to 0.6 gram of methyl-p-hydroxy benzoate, wherein the nicotinamide is nicotinamide hydrate, and the sodium pantothenate is sodium pantothenate hydrate. The water-soluble vitamin for injection has adjustable grain size, concentrated grain size distribution, glabrous surface, high product fluidity, greatly improved stability and high dissolution rate, and a preparation process of the preparation is simple and is favorable for popularization and use.

A method and composition for inhibiting aged skin by topically applying to human skin a topical anti-aging composition. The method involves applying the human skin of afflicted area with an effective amount of the anti-aging composition containing chromium chloride, thiamine mononitrate, magnesium sulfate, and dmae bitartrate for a period of time sufficient to impart the appearance of aged skin. The topical composition is formulated into a pharmaceutically acceptable medium to optimize glucose uptake into the skin cells to properly replace iron production of skin cells, thereby inhibiting the appearance of aged skin.

A radioactive protection micronutrient formulation system is provided and the system comprises: a formulation consisting essentially of antioxidants, the antioxidants are selected from the group consisting essentially of vitamin C, vitamin E, N-acetyl cysteine, natural mixed carotenoids, and alpha-lipoic acid, vitamin A (palmitate), vitamin D-3 (cholecalciferol), thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid, D-Biotin, selenium (1-seleno-methionine), chromium picolinate, zinc glycinate, calcium citrate and magnesium citrate and mixtures thereof; and plus a booster formulation selected from a group consisting essentially of vitamin C, d-alpha tocopheryl acid succinate, alpha tocopherol, N-acetyl cysteine, natural mixed carotenoids and alpha lipoic acid, the formulation is designed to reduce the risk in humans exposed to doses of ionizing radiation of becoming subjected to at least one condition selected from the group consisting essentially of radiation-induced acute leukemia, breast cancer, thyroid cancer and other somatic and heritable mutations.

The invention relates to a water-soluble vitamin pharmaceutical composition for injection. The water-soluble vitamin pharmaceutical composition for injection is prepared from 3.1g of thiamine mononitrate, 40g of nicotinamide, 16.5g of sodium pantothenate, 60mg of biotin, 5.0mg of vitamin B12, 0.5g of disodium ethylene diamine tetraacetate, 4.9g of riboflavin sodium phosphate, 4.9g of pyridoxine hydrochloride, 113g of sodium vitamin C, 0.4g of folic acid, 300g of glycine, 0.5g of methyl parahydroxybenzoate, 1.2g of poloxamer 188, 0.5g of sodium lactate, 1.0g of L-malic acid and water for injection, wherein the water for injection is added until the total volume is 2000ml. The water-soluble vitamin pharmaceutical composition for injection, disclosed by the invention, is good in stability and greatly improved in medication safety.