33 results about "Thiamine mononitrate" patented technology

A method for administering an antioxidant composition to humans according to their age and sex is disclosed wherein the method comprises administering to said humans a daily dose of a multiple antioxidant micronutrient composition comprising vitamin A (palmitate), beta carotene (from natural d. salina), vitamin C (calcium ascorbate), vitamin D-3 (cholecalciferol), natural source vitamin E including both d-alpha tocopheryl and d-alpha tocopheryl acid succinate, thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid (folacin), d-biotin, selenium (1-seleno methionine), chromium picolinate, zinc glycinate, calcium citrate, and magnesium citrate. For persons over the age of about 51, the composition preferably further comprises one or more of co-enzyme Q₁₀, N-acetyl cysteine, and alpha lipoic acid. Preferably, also, vitamin D is added for women over the age of about 36.

The invention provides a novel method for synthesizing a vitamin B1 hydrochloride. The method comprises the following steps of: treating a vitamin B1 sulfate aqueous solution by adopting an ion exchange resin; removing sulfate radicals; and concentrating and crystalizing to prepare the vitamin B1 hydrochloride. Due to the adoption of the method, the conventional process for producing a vitamin B1 hydrochloride by transforming from thiamine mononitrate is eliminated, residues of an organic solvent in a product are avoided since an organic solvent is not adopted, a process for preparing acid methanol from hydrochloric acid gas by using chlorosulfonic acid is eliminated simultaneously, and environmental pollution is lowered.

The invention relates to a compound amino acid capsule (8-11) and a preparation method thereof, specifically to a capsule including pellets of eight amino acids and eleven vitamins and a preparation method thereof. The capsule comprises 7 spherical pellets which are composed of the following raw materials by weight: 2.66 to 9.9 parts of a thiamine mononitrate pellet, 16.35 to 20.5 parts of a vitamin pellet a, 35.0 to 44.1 parts of an amino acid pellet a, 11.4 to 14.4 parts of a vitamin pellet b, 6.65 to 10.5 parts of an amino acid pellet b, 12. 73 to 16.0 parts of a vitamin C pellet and 5.7 to 9.36 parts of a vitamin AD bead. The capsule provided by the invention has the advantages of a scientific and reasonable ratio, good stability, no toxic and side effects, high security and good biological effects and can be applied in preparation of medicines used for treating chronic liver and kidney diseases and of foodstuffs used for alleviating and eliminating physical fatigue caused by exercise training. The capsule provided by the invention has characteristics superior to those of the prior art.

The invention discloses a water-soluble vitamin composition freeze-drying preparation for injection. The freeze-drying preparation comprises the following raw materials and is prepared into 1,000 bottles: 2.8 to 3.4 grams of thiamine mononitrate, 36 to 44 grams of nicotinamide, 4.4 to 5.4 grams of pyridoxine hydrochloride, 14.8 to 18.1 grams of sodium pantothenate, 4.4 to 5.4 grams of riboflavin sodium phosphate, 102 to 124 grams of sodium vitamin C, 54 to 66 milligrams of biotin, 0.36 to 0.44 gram of folic acid, 124.5 to 6.0 milligrams of vitamin B, and 0.4 to 0.6 gram of methyl-p-hydroxy benzoate, wherein the nicotinamide is nicotinamide hydrate, and the sodium pantothenate is sodium pantothenate hydrate. The water-soluble vitamin for injection has adjustable grain size, concentrated grain size distribution, glabrous surface, high product fluidity, greatly improved stability and high dissolution rate, and a preparation process of the preparation is simple and is favorable for popularization and use.

The invention discloses a water-soluble vitamin freeze-dried preparation for injection. 1000 bottles of freeze-dried preparations are prepared from the following raw materials: 2.8-3.4g of thiamine mononitrate, 36-44g of nicotinamide, 4.4-5.4g of pyridoxine hydrochloride, 14.8-18.1g of sodium pantothenate compound, 4.4-5.4g of riboflavin sodium phosphate, 102-124g of sodium ascorbate, 54-66mg of biotin, 0.36-0.44g of folic acid, 4.5-6.0mg of vitamin B12, 0.4-0.6g of methyl p-hydroxybenzoate, 280-320g of glycine, 0.4-0.6g of ethylene diamine tetraacetic acid disodium salt and 2000-3000ml of water for injection. The stability of existing sodium pantothenate is obviously improved by the obtained sodium pantothenate compound, thus ensuring that the sodium pantothenate containing water-soluble vitamin freeze-dried preparation for injection has ideal stability and curative effect and further ensuring medication safety of the patients.

A radioactive protection micronutrient formulation system is provided and the system comprises: a formulation consisting essentially of antioxidants, the antioxidants are selected from the group consisting essentially of vitamin C, vitamin E, N-acetyl cysteine, natural mixed carotenoids, and alpha-lipoic acid, vitamin A (palmitate), vitamin D-3 (cholecalciferol), thiamine mononitrate, riboflavin, niacinamide ascorbate, d-calcium pantothenate, pyridoxine hydrochloride, cyanocobalamin, folic acid, D-Biotin, selenium (1-seleno-methionine), chromium picolinate, zinc glycinate, calcium citrate and magnesium citrate and mixtures thereof; and plus a booster formulation selected from a group consisting essentially of vitamin C, d-alpha tocopheryl acid succinate, alpha tocopherol, N-acetyl cysteine, natural mixed carotenoids and alpha lipoic acid, the formulation is designed to reduce the risk in humans exposed to doses of ionizing radiation of becoming subjected to at least one condition selected from the group consisting essentially of radiation-induced acute leukemia, breast cancer, thyroid cancer and other somatic and heritable mutations.

The invention discloses a concentrated feed for pigs. The concentrated feed for pigs is prepared from the following raw materials in parts by weight: 3-4 parts of calcium dihydrogen phosphate, 0.5-0.6 part of zinc sulfate, 0.03-0.05 part of riboflavin, 0.3-0.5 part of thiamine mononitrate, 2-4 parts of sodium chloride, 270-300 parts of bean pulp, 10-14 parts of lychee exocarp, 1-2 parts of prepared rehmannia roots, 40-50 parts of palm kernel meal, 3-5 parts of dregs of fat, 28-30 parts of a chelated emulsion, 10-13 parts of barley vinegar residues, 1-2 parts of sodium hydrogen sulfite, 30-40 parts of potato slurry residue and 0.1-0.2 part of tocopheryl acetate. Trace elements added into the concentrated feed are less than that in a conventional feed, so that the cost is low; however, the feed still can meet the demand on normal growth and development of pigs.

The invention discloses a method for preparing a thiamine hydrochloride crystal product. Thiamine mononitrate is dispersed into a solvent, and thiamine mononitrate turbid liquid with the concentration of 0.05 g/ml to 0.2 g/ml is obtained, and heated to 50 DEG C to 70 DEG. Chlorosulfonic acid is dropwise added to concentrated hydrochloric acid to generate hydrogen chloride gas, and the gas is introduced into to concentrated sulfuric acid to be dried, and is introduced into the thiamine mononitrate turbid liquid under stirring action. After introduction of the hydrogen chloride gas is completed, heat preservation is carried out for 15 min to 30 min, then the temperature is reduced to 10 DEG C, the cooling rate ranges from 0.1 DEG C/min to 0.5 DEG C/min, filtering, washing and drying are carried out, and then thiamine hydrochloride crystals are prepared. The crystals are rhabdolith, the angle of repose ranges from 31 DEG C to 36.4 DEG C, and the bulk density ranges from 0.50 g/ml to 0.608 g/ml. The thiamine hydrochloride crystal product is good in liquidity. According to the method, the process that thiamine hydrochloride methyl alcohol solvent compounds are formed firstly, then drying is carried out to remove methyl alcohol is avoided, and therefore environmental pollution is reduced, and cost and solvent residues are reduced. The method can be suitable for large-scale production.

The invention relates to an improvement in a crystallization method of thiamine mononitrate. A traditional method comprises the following steps: mixing a crude nitric acid B1, namely, thiamine sulfate solution with an ammonium nitrate aqueous solution in a matched amount, then adding 20%-25% ammonia dropwise until the PH of the mixture reaches 7.2 to 7.5, performing cooling, and separating the solid-liquid mixture to obtain crystals of nitric acid B1. The invention relates to the improvement in the crystallization method of thiamine mononitrate, the mixing sequence and the proportion of three solutions (the thiamine sulfate solution, the ammonium nitrate solution and ammonia) are adjusted, the three solutions are mixed simultaneously, and accordingly, the crystal form of thiamine mononitrate is changed with adoption of the crystallization method. The crystallization method of thiamine mononitrate is improved to replace a traditional crystallization process, the crystal form of a product is changed from the original needle shape into a rod or ball shape, the product particles become larger, the bulk density increases, the packaging volume decreases, and great benefit is provided for reducing the transportation cost and the operating cost and improving the market competitiveness of the product.

The invention relates to a water-soluble vitamin pharmaceutical composition for injection. The water-soluble vitamin pharmaceutical composition for injection is prepared from 3.1g of thiamine mononitrate, 40g of nicotinamide, 16.5g of sodium pantothenate, 60mg of biotin, 5.0mg of vitamin B12, 0.5g of disodium ethylene diamine tetraacetate, 4.9g of riboflavin sodium phosphate, 4.9g of pyridoxine hydrochloride, 113g of sodium vitamin C, 0.4g of folic acid, 300g of glycine, 0.5g of methyl parahydroxybenzoate, 1.2g of poloxamer 188, 0.5g of sodium lactate, 1.0g of L-malic acid and water for injection, wherein the water for injection is added until the total volume is 2000ml. The water-soluble vitamin pharmaceutical composition for injection, disclosed by the invention, is good in stability and greatly improved in medication safety.

The invention discloses a fermented-type dairy product which includes an exercise functional element comprising: vitamin D3, vitamin E acetate, thiamine mononitrate, pyridoxine hydrochloride, nicotinamide, an iron agent, a zinc agent and taurine. The invention also provides two preparation methods of two different fermented-type dairy products, wherein the preparation methods can be respectively used for preparing a milk beverage and yogurt containing the exercise functional element. When the dairy product is prepared, the exercise functional element, a metal chelating agent and a stabilizing agent are added to the dairy product at a certain ratio, so that the dairy product is reduced in fermentation time and fermentation risk, is improved in production efficiency, is reduced in production cost and is relatively increased in nutritional value. In addition, a large amount of nutrients in fermented milk can be digested and absorbed more easily after exercises, and the fermented-type dairy product is ensured in stability during selling and storing.

The invention relates to a preparation method of an enzyme detergent for laboratory ware. According to the technical scheme, the enzyme detergent for laboratory ware is prepared by mixing thiamine mononitrate, protease, bifidobacterium infantis, lipid-soluble coenzyme Q10, polyquaternium, bisabolol, seabuckthorn seed oil, green tea essence, AES, probiotics, tocopheryl phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, okra-seed oil, alkyl polyglucosides(APG0810), enzyme, acetic acid, sweet osmanthus flavor and water.

The invention discloses a preparation method of an enzyme cleanser for air conditioners. According to the technical scheme, the enzyme cleanser for air conditioners is prepared by mixing thiamine mononitrate, protease, bifidobacterium infantis, oat polypeptide, quaternary ammonium salt, bisabolol, avocado oil, green tea essence, AES, probiotics, tocopherol phosphate, capryloyl salicylic acid, azelaic acid, pyridoxine, Kathon 2, fatty alcohol ether sulfate, enzymes, acetic acid, rose flavor, and water.

A water-suspensible, dry, vitamin-hormone horticultural product for promoting plant root growth comprising a combination of one or more plant growth regulators, mycorrhizae, vitamins B1 and B6, sea kelp and beneficial microbes in a carrier. In one embodiment the product is a dry powder of about 2.00 wt % indole-3-butyric acid in crystalline solid form; about 0.20 wt % thiamine mononitrate (B1) in water-soluble powder form; about 0.20 wt % pyridoxine HCl (B6) in water-soluble powder form; about 2.64 wt % Mycorrhizae in water-soluble powder form; about 1.06 wt % sea kelp extract in brown flake form; about 0.88 wt % Bacillus amyloliquefaciens in water-soluble powder form; about 0.07 wt % sodium lauryl sulfoacetate in water-soluble powder form; and about 92.35 wt % maltodextrin in water-soluble powder form.

The invention discloses an enzyme stove cleaning agent. The technical scheme is achieved as follows: the enzyme stove cleaning agent is prepared by mixing thiamine mononitrate, protease, bifidobacterium infantis, tea saponin, ceramide, wheat germ, patchouli oil, green tea flavor, AES, probiotic flora, methylethyl ester, fish collagen protein, citric acid, trehalose, disodium hydrogen phosphate, docusate sodium, an enzyme, ethylic acid, an apple flavor and water.

The invention discloses a fodder for promoting black carp quality. The fodder is prepared from the following components in parts by weight: 35-45 parts of shrimp meal, 10-15 parts of ardisia crenata sims, 16-19 parts of tabernaemontana divaricata, 12-14 parts of leek, 18-24 parts of fructus forsythia, 20-25 parts of schisandra chinensis, 19-23 parts of brucea javanica, 6-9 parts of parmelia tinctourium, 2-5 parts of red halloysite, 15-17 parts of spongilla, 13-19 parts of mussel, 10-16 parts of pig spleen, 6-8 parts of swimming bladder, 0.1-0.3 part of thiamine mononitrate, 0.2-0.4 part of sodium polyacrylate and 0.2-0.5 part of L-carnitine fumarate. The fodder provided by the invention is suitable for the black carp which is heavier than 90g and can supply various nutrient substances required by the black carp in a growth process. After the black carp is fed with the fodder for a long time, the growth speed of the black carp can be effectively increased, the quality of the black carp can be effectively improved, and the nutrition value of the black carp can be greatly increased.