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Compound amino acid capsule including eight amino acids and eleven vitamins

A vitamin and amino acid technology, applied in capsule delivery, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as poor product stability, poor product stability of amino acid oral preparations, and decreased product content.

Active Publication Date: 2014-11-05
SHENZHEN WANHE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the instability of amino acids, the stability of amino acid oral preparations is poor, which restricts the application of amino acid oral preparations
Chinese patent CN1781486, the name of the invention is: a compound amino acid and vitamin capsule preparation and its preparation method. The formula and preparation method of this invention are different from those of the product of the present invention. After testing, it is found that the product prepared by this invention The stability is not good, at 12 months, the appearance of the product changes color obviously and the product content drops obviously
However, the inventors found that the different properties of the 7 kinds of micropills caused the phenomenon that the content of individual micropills was obviously uneven when the micropills were mixed and filled into capsules.

Method used

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  • Compound amino acid capsule including eight amino acids and eleven vitamins
  • Compound amino acid capsule including eight amino acids and eleven vitamins
  • Compound amino acid capsule including eight amino acids and eleven vitamins

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0106] The formula of 8 kinds of amino acids and 11 kinds of vitamin pellet capsules of the present invention is: wherein thiamine nitrate pellets, vitamin pellets a, amino acid pellets a, vitamin pellets b, amino acid pellets b, vitamin C pellets and vitamin AD The weight ratio of these seven kinds of micropill circular micropills of microbead is:

[0107] Thiamine nitrate pellets 6.88 Vitamin pellets a 17.1 Amino Acid Pellets a 36.8 Vitamin pellets b 12 Amino acid pellets b 7.56 Vitamin C Pellets 13.4 Vitamin AD microbeads 6.2

[0108] 1. The formula of thiamine nitrate pellets is:

[0109] Thiamine nitrate 250g lactose 450g starch 45g Calcium Carboxymethyl Cellulose 75g Methylcellulose 22g Hydroxypropyl Cellulose 19g Titanium dioxide 23g microcrystalline cellulose 116g

[0110] 2. The formula of vitamin micropills a is:

[0111] Nicotinamide 360g thbr...

Embodiment 2

[0131] The formula of 8 kinds of amino acids of the present invention and 11 kinds of vitamin micropill capsules is:

[0132] Wherein the weight ratio of these seven pellets of thiamine nitrate pellets, vitamin pellets a, amino acid pellets a, vitamin pellets b, amino acid pellets b, vitamin C pellets and vitamin AD pellets is:

[0133] Thiamine nitrate pellets 2.66 Vitamin pellets a 16.35 Amino Acid Pellets a 35.0 Vitamin pellets b 11.4 Amino acid pellets b 6.65 Vitamin C Pellets 12.73 Vitamin AD microbeads 5.7

[0134] 1. The formula of thiamine nitrate pellets is:

[0135] Thiamine nitrate 76g lactose 225g starch 9g Calcium Carboxymethyl Cellulose 15g Methylcellulose 4.4g Hydroxypropyl Cellulose 3.8g Titanium dioxide 4.6g microcrystalline cellulose 58g

[0136] 2. The formula of vitamin micropills a is:

[0137] Nicotinamide 245g thbrthdrexvbdr 62g ...

Embodiment 3

[0158] The formula of 8 kinds of amino acids and 11 kinds of vitamin micropellets capsules is:

[0159] Thiamin nitrate pellets, vitamin pellets a, amino acid pellets a, vitamin pellets b, amino acid pellets b, vitamin C pellets and vitamin AD pellets, the weight ratio of these seven pellets is:

[0160] Thiamine nitrate pellets 9.9

[0161] Vitamin pellets a 20.5 Amino Acid Pellets a 44.1 Vitamin pellets b 14.4 Amino acid pellets b 10.5 Vitamin C Pellets 16.0 Vitamin AD microbeads 9.36

[0162] 1. The formula of thiamine nitrate pellets is:

[0163] Thiamine nitrate 300g lactose 675g starch 81g Calcium Carboxymethyl Cellulose 135g Methylcellulose 39.6g Hydroxypropyl Cellulose 34.2g Titanium dioxide 41.4g microcrystalline cellulose 174g

[0164] 2. The formula of vitamin micropills a is:

[0165] Nicotinamide 580g thbrthdrexvbdr 145g Vita...

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Abstract

The invention relates to a compound amino acid capsule (8-11) and a preparation method thereof, specifically to a capsule including pellets of eight amino acids and eleven vitamins and a preparation method thereof. The capsule comprises 7 spherical pellets which are composed of the following raw materials by weight: 2.66 to 9.9 parts of a thiamine mononitrate pellet, 16.35 to 20.5 parts of a vitamin pellet a, 35.0 to 44.1 parts of an amino acid pellet a, 11.4 to 14.4 parts of a vitamin pellet b, 6.65 to 10.5 parts of an amino acid pellet b, 12. 73 to 16.0 parts of a vitamin C pellet and 5.7 to 9.36 parts of a vitamin AD bead. The capsule provided by the invention has the advantages of a scientific and reasonable ratio, good stability, no toxic and side effects, high security and good biological effects and can be applied in preparation of medicines used for treating chronic liver and kidney diseases and of foodstuffs used for alleviating and eliminating physical fatigue caused by exercise training. The capsule provided by the invention has characteristics superior to those of the prior art.

Description

technical field [0001] The present invention relates to a micropill capsule and a preparation method thereof. Specifically, it relates to a capsule containing 8 kinds of amino acids and 11 kinds of vitamin micropills, which can also be called compound amino acid capsule (8-11), and also relates to the capsule method of preparation. Background technique [0002] Protein is the material basis of human life activities. Various physiological functions of the human body, especially immune function, cell damage repair function and growth and development function, are closely related to the normality of its metabolism. Under normal circumstances, the human body obtains various amino acids through the protein in food to ensure the normal protein metabolism of the body. Among the 20 kinds of amino acids needed for human protein synthesis, 8 kinds of amino acids are essential amino acids for the human body. These 8 kinds of amino acids cannot be synthesized by the body itself and mus...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/714A61K31/59A61K31/525A61K31/519A61K31/51A61K31/455A61K31/4415A61K31/405A61K31/375A61K31/355A61K31/198A61K31/197A61K31/195A61K31/07A61K9/48A61P3/02
Inventor 衷期群曾德文姚向红杨松林
Owner SHENZHEN WANHE PHARMA
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