The invention relates to a health food with functions of detoxifying and losing weight and a preparation method thereof. According to the health food, 10-20 percent of maca powder, 10-30 percent of konjaku flour, 10-20 percent of aloe powder, 5-10 percent of grape seed extract, 5-15 percent of hawthorn extract and 5-15 percent of jelly fungi extract by weight percent are selected as main raw materials, and 0-45 percent of auxiliary material allowable in health foods is added, the main raw material added with the auxiliary material is prepared into tablets, soft capsules, capsules or granules. The health food has the advantages of natural raw materials, scientific ratio, convenience in taking, security and nontoxicity, the synergistic effect is achieved through all ingredients, and the health food has multiple efficacy of supplementing intestinal fiber, lubricating intestines and detoxifying, losing weight and lowering lipid, and is a green health food for patients suffering from hyperlipidemia, constipation and obesity.