11 results about "Thiamine Hydrochloride" patented technology

The application provides a sulfate-reducing bacteria culture medium and application thereof, and components of the culture medium include: a carbon source, a nitrogen source, a phosphorus source, calcium chloride, magnesium chloride, an inorganic sulfur source, an organic sulfur compound with reducibility, inorganic trace elements, agar and water; wherein the mass content of the organic sulfur compound with reducibility is 5-30 mg / L, the mass content of the inorganic trace elements is 152-365 mg / L; the organic sulfur compound with reducibility includes lipoic acid and / or thiamine hydrochloride; and the inorganic trace elements include a combination of zinc elements, manganese elements, molybdenum elements and boron elements. The application introduces inorganic trace elements required by biological cell metabolism and rich sulfur electron acceptor species, promotes the growth and metabolism process of sulfate-reducing bacteria, and enables SRB cells to form visible colonies at a faster speed.

The invention relates to a high-yield vitamin B12 strain with improved robustness and application of the high-yield vitamin B12 strain, and belongs to the technical field of microbial fermentation and metabolic engineering. According to the invention, a pseudomonas denitrificans original production strain capable of synthesizing the vitamin B12 is evolved by a long-term adaptive laboratory taking the vitamin B12 and a structural analogue thiamine hydrochloride thereof as selection pressure. The evolved strain shows significantly enhanced growth ability and fermentation stability in a high stress environment, and the highest yield of vitamin B12 can reach 314 mg / L, which is 38.7% higher than that of an original strain, which is the highest level reported at present. Moreover, stable production can be realized on a 7 L fermentation tank, and good batch stability is realized. The invention also provides application of the strain in industrial production of the vitamin B12, and the strain has important significance in reducing the production cost of the vitamin B12 and improving the fermentation efficiency.

This invention belongs to the field of biomedical technology, and specifically relates to a nutrient composition for the prevention and / or treatment of post-traumatic stress disorder (PTSD). This invention utilizes metabolomics technology to screen and identify metabolite changes occurring during the pathophysiological process of PTSD, and then designs a nutrient composition comprising five components: α-ketoglutarate, thiamine hydrochloride, L-serine, L-tryptophan, and L-tyrosine. Combined supplementation of these five nutrient components effectively improves anxiety-like behavior and promotes the extinction of fear memories in PTSD model mice. Furthermore, the nutrient composition of this invention exhibits extremely high safety, with side effects far lower than traditional chemically synthesized drugs, and is expected to improve long-term patient adherence.

The application relates to the technical field of microbial culture medium, and discloses a chemical component limited culture medium for supporting growth of bifidobacterium and application thereof. The CDM comprises a carbon source, salts, amino acids, vitamins and water; the carbon source is selected from at least one of glucose, fructose, lactose, maltose and galactooligosaccharide, the salts comprise sodium acetate, potassium hydrogen phosphate, ammonium acetate, magnesium sulfate heptahydrate, ferrous sulfate heptahydrate, sodium chloride and manganese sulfate monohydrate, the amino acids comprise alanine, cystine, cysteine, tryptophan and asparagine, and the vitamins comprise pyridoxine hydrochloride, nicotinic acid, calcium pantothenate, thiamine hydrochloride, riboflavin, p-aminobenzoic acid, folic acid and biotin. The CDM of the application is a liquid culture medium, only comprises 21 definite components, is simple in components, convenient in preparation, and is high in universality, and can effectively support growth of bifidobacterium.

The invention relates to the field of compound preparation, in particular to a method for preparing thiamine hydrochloride. The method comprises the following steps: carrying out contact reaction on thiamine nitrate, ammonium chloride and hydrogen chloride under the condition of an organic solvent, and separating reaction liquid to obtain thiamine hydrochloride solid. Compared with the prior art, ammonium chloride is used for replacing part of hydrochloric acid to participate in the reaction in the thiamine hydrochloride production process, so that the dosage of hydrochloric acid is reduced, equipment corrosion can be reduced, subsequent wastewater treatment steps are simplified, the product yield is not influenced, the content of other impurities is not increased, new production equipment is not added, and the production cost is effectively saved; furthermore, the materials are recycled, so that a more environment-friendly and cost-saving process route can be realized.

The invention discloses a culture medium for promoting germination of saussurea involucrata seeds and increasing the flavone content in a cell culture and application of the culture medium. Multivitamins for promoting germination of saussurea involucrata seeds and increasing the flavone content in the cell culture comprise thiamine hydrochloride VB1, nicotinic acid and pyridoxine hydrochloride VB6; wherein the concentration of thiamine hydrochloride VB1 is 1000 mg / L, the concentration of nicotinic acid is 500 mg / L, and the concentration of pyridoxine hydrochloride VB6 is 500 mg / L. A mixed mother solution (V3 vitamin for short) of three vitamins is prepared for filtration, sterilization and addition, the concentrations of the three vitamins are thiamine hydrochloride VB11000 mg / L, nicotinic acid 500 mg / L and pyridoxine hydrochloride VB6500 mg / L respectively, the overall addition amount of V3 is 1 mL / L, the germination rate of saussurea involucrata seeds can be effectively improved, and the germination rate of the seeds is 40.58%.

The present application relates to a kind of method for improving the content of meaty substance in thiamine degradation product and the application of degradation product, belong to food processing technical field.Through the thiamine hydrochloride, food additive and solvent are added in closed reaction container, stirring reaction 10-180min under 80-140 ℃, after reaction, cooling, obtain thiamine degradation product.The method can greatly improve the generation amount of meaty compound in thiamine degradation process, thiamine degradation product can be directly used in reaction essence preparation, enhance meaty, reduce cost.In addition, by edible oil or capric caprylic acid glyceride, thiamine degradation product is extracted, separated and dried, obtain meaty seasoning oil, remove bitter substance in taste, for meaty reaction or flavoring product, also can play the role of enhancing meaty, reducing cost, with wide application prospect.

Provided is a transfection reagent, comprising a solvent, organic substances, amino acids, vitamins and inorganic salts, wherein the organic substances comprise D-glucose, sodium pyruvate, i-inositol, phenol red and choline chloride; the amino acids comprise glycine, L-glutamine, L-valine, L-isoleucine, L-leucine, L-threonine, L-lysine hydrochloride, L-phenylalanine, L-serine, L-tyrosine disodium salt, L-arginine hydrochloride, L-methionine, L-cystine dihydrochloride, L-histidine hydrochloride and L-tryptophan; the vitamins comprise nicotinamide, pyridoxine hydrochloride, thiamine hydrochloride, folic acid, D-calcium pantothenate and riboflavin; and the inorganic salts comprise sodium chloride, sodium bicarbonate, potassium chloride, calcium chloride, sodium dihydrogen phosphate, magnesium sulfate, hydrochloric acid and ferric nitrate. The transfection reagent is suitable for a wide range of applications, achieves the rapid onset of transfection, and has a good transfection effect.

The invention relates to the technical field of brightener processing, in particular to an acid copper plating brightener, an acid copper plating electroplating solution and an electroplating technology of the acid copper plating brightener. The cleaning agent is prepared from the following raw materials by concentration: 50-100 g / L of octadecylamine polyoxyethylene ether, 10-20 g / L of thiamine hydrochloride, 5-30 g / L of polydiaminourea, 20-40 g / L of aspirin sodium and 80-120 g / L of a surfactant. According to the brightening agent, through the synergistic effect of all the components, the problems that a traditional brightening agent is prone to scorching, fogging and coarse crystallization under the high current density are effectively solved, the contradiction between deep hole filling and plate surface brightness is balanced, the dog-bone-shaped distribution and cavity defects in high-thickness-diameter-ratio through hole electroplating are overcome, and overplating and stripes in a low-current area are avoided. The obtained copper plating layer is fine in crystallization, bright and flat, the interlayer interconnection reliability and the microscopic uniform plating capacity are remarkably improved, the method is matched with the VCP vertical continuous electroplating technology, and the light, thin and high-frequency manufacturing requirements of high-density and fine circuit PCBs are met.

This invention provides a low-salt flavored pork bone paste and its preparation method, belonging to the field of food processing technology. The preparation method includes the following steps: using pork bone paste as raw material, a basic enzymatic hydrolysate is prepared by low-temperature ultrasound-assisted papain hydrolysis; thiamine hydrochloride, D-xylose, and L-cysteine ​​hydrochloride are sequentially added to the basic enzymatic hydrolysate to conduct a Maillard reaction, resulting in a hot reaction solution; a flavor regulator and a thickener are added to the hot reaction solution to obtain the low-salt flavored pork bone paste. This invention efficiently prepares an enzymatic hydrolysate substrate rich in small molecule peptides and amino acids through low-temperature intermittent ultrasound-assisted enzymatic hydrolysis; it employs a three-step Maillard reaction with stepwise feeding to directionally generate core meat flavor substances and avoid sulfurous odors; furthermore, a low-salt formula with potassium chloride as the main salt and synergistic stability of compound phosphate and calcium lactate can be used to significantly reduce sodium content and give the product a delicate and stable paste texture.

This invention discloses a bergamot effervescent tablet based on microencapsulation technology and its preparation method, relating to the field of solid beverage technology. The invention comprises, based on a total feed weight of 100 kg, the following components: bergamot extract; 3 kg; anhydrous citric acid; 18 kg; sodium bicarbonate; 15 kg; dextrin; 45 kg; gum arabic; 0.6 kg; tragacanth gum; 0.15 kg; taurine; 1.58 kg; zinc gluconate; 0.75 kg; zinc citrate; 0.25 kg; calcium gluconate; 0.25 kg; ascorbic acid C; 0.1 kg; ferrous gluconate; 0.11 kg; thiamine hydrochloride; 0.058 kg; riboflavin; 0.03 kg; pyridoxine hydrochloride; 0.02 kg; cyanocobalamin; 0.001 kg; folic acid; 0.001 kg; isomaltitol; 15 kg; sucralose; 0.1 kg. The advantages are: through systematic screening of key factors such as the inclusion of aromatic oil components in bergamot extract, the ratio of acid-base disintegrants, the ratio of flavoring agents and food fortifiers, the type of fillers, the preparation method of acid-base particles, and the tableting process parameters.