The invention discloses a cultivation method of dendrobium officinale and a special nutrient solution thereof. The nutrient solution is composed of solutes and a solvent. The solvent is water, and the solutes include an N source, a P source, a K source, a Ca source, a Mg source, a Fe source, a B source, an Mn source, a Zn source, a Cu source and a Mo source, wherein the mass ratio of N element, P element, K element, Ca element and Mg element in the N source, the P source, the K source, the Ca source, the Mg source is (3-5): (1-4): (1-4): (1.5-2.5): 1. According to the cultivation method of the dendrobium officinale, solid culture can be performed under suitable artificial light or natural light, growth and development of the dendrobium officinale can be promoted, production cycle can be shortened, and yield and quality of the dendrobium officinale can be improved finally. Therefore, the cultivation method of the dendrobium officinale and the special nutrient solution thereof have broad application prospects.